Review: Targeting the Hedgehog pathway in cancer

Therapeutic Advances in Medical Oncology

Volumn 2, Issue 4, 2010, Pages 237-250

  Gupta, Sachin ^a   Takebe, Naoko ^b   Lorusso, Patricia ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

basal cell carcinoma; cancer stem cells; GDC 0449; Hedgehog; medulloblastoma

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; BMS 833923; CYCLOPAMINE; ERLOTINIB; GDC 0449; GEMCITABINE; HH ANTAG 691; IPI 926; ITRACONAZOLE; MK 4101; N (3 METHOXYBENZYL) 3,3 DIMETHYL N [1 (3,4 METHYLENEDIOXYBENZYL) 2 (1 PIPERAZINYLCARBONYL) 4 PYRROLIDINYL]BUTYRAMIDE; PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG;

ADVANCED CANCER; AUTOCRINE EFFECT; BASAL CELL CARCINOMA; BASAL CELL NEVUS SYNDROME; BRAIN TUMOR; BREAST TUMOR; CANCER STEM CELL; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; COLORECTAL CANCER; DYSPEPSIA; EPITHELIAL MESENCHYMAL TRANSITION; ESOPHAGUS TUMOR; FATIGUE; HAIR LOSS; HEART ATRIUM FIBRILLATION; HUMAN; HYPONATREMIA; LEUKEMIA; LIVER TUMOR; LUNG SMALL CELL CANCER; LUNG TUMOR; LYMPHOMA; MEDULLOBLASTOMA; MOLECULARLY TARGETED THERAPY; MULTIPLE MYELOMA; MUSCLE SPASM; MUTATION; NAUSEA AND VOMITING; NONHUMAN; OVARY CANCER; PANCREAS CANCER; PANCREAS TUMOR; PARACRINE SIGNALING; PRIORITY JOURNAL; PROSTATE TUMOR; REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; SOLID TUMOR; STOMACH TUMOR; TASTE DISORDER; WEIGHT REDUCTION;

EID: 78649247495     PISSN: 17588340     EISSN: None     Source Type: Journal    
DOI: 10.1177/1758834010366430     Document Type: Review

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