Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: Conditional skin tumorigenesis recapitulates the hair growth cycle

Genes and Development

Volumn 19, Issue 2, 2005, Pages 214-223

  Hutchin, Mark E ^a   Kariapper, Muhammed S T ^a   Grachtchouk, Marina ^a   Wang, Aiqin ^a   Wei, Lebing ^a   Cummings, Donelle ^a   Liu, Jianhong ^a   Evan Michael, L ^a   Glick, Adam ^b   Dlugosz, Andrzej A ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Basal cell carcinoma; Gli2; Hair follicle; Hedgehog signaling; Organogenesis; Tumorigenesis

Indexed keywords

SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BASAL CELL CARCINOMA; CARCINOGENESIS; CELL LINEAGE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GENE INACTIVATION; HAIR FOLLICLE; HAIR GROWTH; MOUSE; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENE;

ANIMALS; APOPTOSIS; CARCINOMA, BASAL CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HAIR FOLLICLE; HEDGEHOG PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; STEM CELLS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ANIMALIA; ERINACEIDAE;

EID: 19944429892     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1258705     Document Type: Article

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