A switch from life to death in endoplasmic reticulum stressed β-cells

Diabetes, Obesity and Metabolism

Volumn 12, Issue SUPPL. 2, 2010, Pages 58-65

  Oslowski, C M ^a   Urano, F ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Beta cell death; Binary switch; Diabetes; Endoplasmic reticulum stress; Unfolded protein response; Wolfram syndrome

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; INOSITOL REQUIRING 1; INSULIN; PKR LIKE ENDOPLASMIC RETICULUM KINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHOSPHORYLATION; CELL DEATH; CELL FATE; CELL SURVIVAL; CELLULAR STRESS RESPONSE; ENDOPLASMIC RETICULUM STRESS; ENVIRONMENTAL FACTOR; FEEDBACK SYSTEM; GENE CONTROL; HEREDITY; HOMEOSTASIS; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PATHOGENESIS; PROTEIN FOLDING; PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; WOLFRAM SYNDROME;

EID: 77957303908     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2010.01277.x     Document Type: Article

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