-
1
-
-
0035480050
-
TGF-β signalling pathways in early Xenopus development
-
Hill, C. S. (2001) TGF-β signalling pathways in early Xenopus development. Curr. Opin. Genet. Dev. 11, 533-540
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 533-540
-
-
Hill, C.S.1
-
2
-
-
0035504887
-
Intracellular BMP signaling regulation in vertebrates: Pathway or network?
-
von Bubnoff, A. and Cho, K. W. (2001) Intracellular BMP signaling regulation in vertebrates: pathway or network? Dev. Biol. 239, 1-14
-
(2001)
Dev. Biol.
, vol.239
, pp. 1-14
-
-
Bubnoff, A.1
Cho, K.W.2
-
3
-
-
0032529159
-
Smads and early developmental signaling by the TGFβ superfamily
-
Whitman, M. (1998) Smads and early developmental signaling by the TGFβ superfamily. Genes Dev. 12, 2445-2462
-
(1998)
Genes Dev.
, vol.12
, pp. 2445-2462
-
-
Whitman, M.1
-
4
-
-
0038682002
-
Mechanisms of TGF-β signaling from cell membrane to the nucleus
-
Shi, Y. and Massague, J. (2003) Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 113, 685-700
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
5
-
-
40849133772
-
Role of transforming growth factor-β superfamily signaling pathways in human disease
-
Gordon, K. J. and Blobe, G. C. (2008) Role of transforming growth factor-β superfamily signaling pathways in human disease. Biochim. Biophys. Acta 1782, 197-228
-
(2008)
Biochim. Biophys. Acta
, vol.1782
, pp. 197-228
-
-
Gordon, K.J.1
Blobe, G.C.2
-
7
-
-
2442706881
-
Alterations of cell signaling pathways in pancreatic cancer
-
Freeman, J. W., DeArmond, D., Lake, M., Huang, W., Venkatasubbarao, K. and Zhao, S. (2004) Alterations of cell signaling pathways in pancreatic cancer. Front. Biosci. 9, 1889-1898
-
(2004)
Front. Biosci.
, vol.9
, pp. 1889-1898
-
-
Freeman, J.W.1
DeArmond, D.2
Lake, M.3
Huang, W.4
Venkatasubbarao, K.5
Zhao, S.6
-
8
-
-
7244253108
-
Transforming growth factor-β (TGF-β) activates cytosolic phospholipase A2α (cPLA2α)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-γ (PPAR-γ)/Smad signaling pathways in human liver cancer cells. A novel mechanism for subversion of TGF-β-induced mitoinhibition
-
Han, C., Demetris, A. J., Liu, Y., Shelhamer, J. H. and Wu, T. (2004) Transforming growth factor-β (TGF-β) activates cytosolic phospholipase A2α (cPLA2α)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-γ (PPAR-γ)/Smad signaling pathways in human liver cancer cells. A novel mechanism for subversion of TGF-β-induced mitoinhibition. J. Biol. Chem. 279, 44344-44354
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44344-44354
-
-
Han, C.1
Demetris, A.J.2
Liu, Y.3
Shelhamer, J.H.4
Wu, T.5
-
9
-
-
0242499448
-
Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
-
Siegel, P. M. and Massague, J. (2003) Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer. Nat. Rev. Cancer 3, 807-821
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 807-821
-
-
Siegel, P.M.1
Massague, J.2
-
10
-
-
2942519197
-
Antifibrotic therapy in scleroderma: Extracellular or intracellular targeting of activated fibroblasts?
-
Varga, J. (2004) Antifibrotic therapy in scleroderma: extracellular or intracellular targeting of activated fibroblasts? Curr. Rheumatol. Rep. 6, 164-170
-
(2004)
Curr. Rheumatol. Rep.
, vol.6
, pp. 164-170
-
-
Varga, J.1
-
11
-
-
0036467496
-
TGF-β signaling: Positive and negative effects on tumorigenesis
-
Wakefield, L. M. and Roberts, A. B. (2002) TGF-β signaling: positive and negative effects on tumorigenesis. Curr. Opin. Genet. Dev. 12, 22-29
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 22-29
-
-
Wakefield, L.M.1
Roberts, A.B.2
-
12
-
-
33847716712
-
Negative regulation of TGF-β receptor/Smad signal transduction
-
Itoh, S. and ten Dijke, P. (2007) Negative regulation of TGF-β receptor/Smad signal transduction. Curr. Opin. Cell Biol. 19, 176-184
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 176-184
-
-
Itoh, S.1
Ten Dijke, P.2
-
13
-
-
0037351880
-
The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly
-
DOI 10.1016/S1097-2765(03)00094-7
-
Greenwald, J., Groppe, J., Gray, P., Wiater, E., Kwiatkowski, W., Vale, W. and Choe, S. (2003) The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly. Mol. Cell 11, 605-617 (Pubitemid 36385117)
-
(2003)
Molecular Cell
, vol.11
, Issue.3
, pp. 605-617
-
-
Greenwald, J.1
Groppe, J.2
Gray, P.3
Wiater, E.4
Kwiatkowski, W.5
Vale, W.6
Choe, S.7
-
14
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning, G., Whyte, D. B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science 298, 1912-1934
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
15
-
-
0034043106
-
Crystal structure of the BMP-2-BRIA ectodomain complex
-
Kirsch, T., Sebald, W. and Dreyer, M. K. (2000) Crystal structure of the BMP-2-BRIA ectodomain complex. Nat. Struct. Biol. 7, 492-496
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 492-496
-
-
Kirsch, T.1
Sebald, W.2
Dreyer, M.K.3
-
16
-
-
0036069143
-
The 1.1 A crystal structure of human TGF-β type II receptor ligand binding domain
-
Boesen, C. C., Radaev, S., Motyka, S. A., Patamawenu, A. and Sun, P. D. (2002) The 1.1 A crystal structure of human TGF-β type II receptor ligand binding domain. Structure 10, 913-919
-
(2002)
Structure
, vol.10
, pp. 913-919
-
-
Boesen, C.C.1
Radaev, S.2
Motyka, S.A.3
Patamawenu, A.4
Sun, P.D.5
-
17
-
-
34248584887
-
Src phosphorylates Tyr284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during breast cancer cell proliferation and invasion
-
Galliher, A. J. and Schiemann, W. P. (2007) Src phosphorylates Tyr284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during breast cancer cell proliferation and invasion. Cancer Res. 67, 3752-3758
-
(2007)
Cancer Res.
, vol.67
, pp. 3752-3758
-
-
Galliher, A.J.1
Schiemann, W.P.2
-
18
-
-
0030972496
-
Positive and negative regulation of type II TGF-β receptor signal transduction by autophosphorylation on multiple serine residues
-
Luo, K. and Lodish, H. F. (1997) Positive and negative regulation of type II TGF-β receptor signal transduction by autophosphorylation on multiple serine residues. EMBO J. 16, 1970-1981
-
(1997)
EMBO J.
, vol.16
, pp. 1970-1981
-
-
Luo, K.1
Lodish, H.F.2
-
19
-
-
0030978105
-
The type II transforming growth factor-β receptor autophosphorylates not only on serine and threonine but also on tyrosine residues
-
Lawler, S., Feng, X. H., Chen, R. H., Maruoka, E. M., Turck, C. W., Griswold-Prenner, I. and Derynck, R. (1997) The type II transforming growth factor-β receptor autophosphorylates not only on serine and threonine but also on tyrosine residues. J. Biol. Chem. 272, 14850-14859
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14850-14859
-
-
Lawler, S.1
Feng, X.H.2
Chen, R.H.3
Maruoka, E.M.4
Turck, C.W.5
Griswold-Prenner, I.6
Derynck, R.7
-
20
-
-
0028170226
-
Mechanism of activation of the TGF-β receptor
-
Wrana, J. L., Attisano, L., Wieser, R., Ventura, F. and Massague, J. (1994) Mechanism of activation of the TGF-β receptor. Nature 370, 341-347
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Wieser, R.3
Ventura, F.4
Massague, J.5
-
21
-
-
1442299193
-
Lateral signaling enhances TGF-β response complexity
-
Byfield, S. D. and Roberts, A. B. (2004) Lateral signaling enhances TGF-β response complexity. Trends Cell Biol. 14, 107-111
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 107-111
-
-
Byfield, S.D.1
Roberts, A.B.2
-
22
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signalling
-
Derynck, R. and Zhang, Y. E. (2003) Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425, 577-584
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
23
-
-
23044466047
-
Specificity and versatility in TGF-β signaling through Smads
-
Feng, X. H. and Derynck, R. (2005) Specificity and versatility in TGF-β signaling through Smads. Annu. Rev. Cell. Dev. Biol. 21, 659-693
-
(2005)
Annu. Rev. Cell. Dev. Biol.
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
24
-
-
0034678908
-
Transcriptional control by the TGF-β/Smad signaling system
-
Massague, J. and Wotton, D. (2000) Transcriptional control by the TGF-β/Smad signaling system. EMBO J. 19, 1745-1754 (Pubitemid 30204386)
-
(2000)
EMBO Journal
, vol.19
, Issue.8
, pp. 1745-1754
-
-
Massague, J.1
Wotton, D.2
-
25
-
-
2342488852
-
New insights into TGF-β-Smad signalling
-
ten Dijke, P. and Hill, C. S. (2004) New insights into TGF-β-Smad signalling. Trends Biochem. Sci. 29, 265-273
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 265-273
-
-
Ten Dijke, P.1
Hill, C.S.2
-
26
-
-
0029931509
-
A human Mad protein acting as a BMP-regulated transcriptional activator
-
Liu, F., Hata, A., Baker, J. C., Doody, J., Carcamo, J., Harland, R. M. and Massague, J. (1996) A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620-623
-
(1996)
Nature
, vol.381
, pp. 620-623
-
-
Liu, F.1
Hata, A.2
Baker, J.C.3
Doody, J.4
Carcamo, J.5
Harland, R.M.6
Massague, J.7
-
27
-
-
0034252221
-
Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal
-
Watanabe, M., Masuyama, N., Fukuda, M. and Nishida, E. (2000) Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal. EMBO Rep. 1, 176-182
-
(2000)
EMBO Rep.
, vol.1
, pp. 176-182
-
-
Watanabe, M.1
Masuyama, N.2
Fukuda, M.3
Nishida, E.4
-
28
-
-
0034608799
-
A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation
-
Xiao, Z., Liu, X., Henis, Y. I. and Lodish, H. F. (2000) A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation. Proc. Natl. Acad. Sci. U.S.A. 97, 7853-7858
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 7853-7858
-
-
Xiao, Z.1
Liu, X.2
Henis, Y.I.3
Lodish, H.F.4
-
29
-
-
0034253480
-
The nuclear import function of Smad2 is masked by SARA and unmasked by TGFβ-dependent phosphorylation
-
Xu, L., Chen, Y. G. and Massague, J. (2000) The nuclear import function of Smad2 is masked by SARA and unmasked by TGFβ-dependent phosphorylation. Nat. Cell Biol. 2, 559-562
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 559-562
-
-
Xu, L.1
Chen, Y.G.2
Massague, J.3
-
30
-
-
0033956131
-
Signaling inputs converge on nuclear effectors in TGF-β signaling
-
ten Dijke, P., Miyazono, K. and Heldin, C. H. (2000) Signaling inputs converge on nuclear effectors in TGF-β signaling. Trends Biochem. Sci. 25, 64-70
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 64-70
-
-
Ten Dijke, P.1
Miyazono, K.2
Heldin, C.H.3
-
31
-
-
0033380665
-
TGF-β signaling from receptors to the nucleus
-
Roberts, A. B. (1999) TGF-β signaling from receptors to the nucleus. Microbes Infect. 1, 1265-1273
-
(1999)
Microbes Infect.
, vol.1
, pp. 1265-1273
-
-
Roberts, A.B.1
-
32
-
-
70450187617
-
The regulation of TGFβ signal transduction
-
Moustakas, A. and Heldin, C. H. (2009) The regulation of TGFβ signal transduction. Development 136, 3699-3714
-
(2009)
Development
, vol.136
, pp. 3699-3714
-
-
Moustakas, A.1
Heldin, C.H.2
-
33
-
-
33745188200
-
Smad7 and protein phosphatase 1α are critical determinants in the duration of TGF-β/ALK1 signaling in endothelial cells
-
Valdimarsdottir, G., Goumans, M. J., Itoh, F., Itoh, S., Heldin, C. H. and ten Dijke, P. (2006) Smad7 and protein phosphatase 1α are critical determinants in the duration of TGF-β/ALK1 signaling in endothelial cells. BMC Cell Biol. 7, 16
-
(2006)
BMC Cell Biol.
, vol.7
, pp. 16
-
-
Valdimarsdottir, G.1
Goumans, M.J.2
Itoh, F.3
Itoh, S.4
Heldin, C.H.5
Ten Dijke, P.6
-
34
-
-
58249089671
-
Holding their own: The noncanonical roles of Smad proteins
-
Hoover, L. L. and Kubalak, S. W. (2008) Holding their own: the noncanonical roles of Smad proteins. Sci. Signaling 1, pe48
-
(2008)
Sci. Signaling
, vol.1
, pp. 48
-
-
Hoover, L.L.1
Kubalak, S.W.2
-
35
-
-
35048875855
-
TGF-β signaling: A tale of two responses
-
Rahimi, R. A. and Leof, E. B. (2007) TGF-β signaling: a tale of two responses. J. Cell. Biochem. 102, 593-608
-
(2007)
J. Cell. Biochem.
, vol.102
, pp. 593-608
-
-
Rahimi, R.A.1
Leof, E.B.2
-
36
-
-
55449107515
-
Regulation of TGF-β family signaling by E3 ubiquitin ligases
-
Inoue, Y. and Imamura, T. (2008) Regulation of TGF-β family signaling by E3 ubiquitin ligases. Cancer Sci. 99, 2107-2112
-
(2008)
Cancer Sci.
, vol.99
, pp. 2107-2112
-
-
Inoue, Y.1
Imamura, T.2
-
37
-
-
0033549789
-
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation
-
Zhu, H., Kavsak, P., Abdollah, S., Wrana, J. L. and Thomsen, G. H. (1999) A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature 400, 687-693
-
(1999)
Nature
, vol.400
, pp. 687-693
-
-
Zhu, H.1
Kavsak, P.2
Abdollah, S.3
Wrana, J.L.4
Thomsen, G.H.5
-
38
-
-
0034711290
-
Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-β signaling
-
Lin, X., Liang, M. and Feng, X. H. (2000) Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-β signaling. J. Biol. Chem. 275, 36818-36822
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36818-36822
-
-
Lin, X.1
Liang, M.2
Feng, X.H.3
-
39
-
-
0035970096
-
Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase
-
Zhang, Y., Chang, C., Gehling, D. J., Hemmati-Brivanlou, A. and Derynck, R. (2001) Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A. 98, 974-979
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 974-979
-
-
Zhang, Y.1
Chang, C.2
Gehling, D.J.3
Hemmati-Brivanlou, A.4
Derynck, R.5
-
40
-
-
15944370597
-
NEDD4-NEDD2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-β (transforming growth factor-β) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-β type I receptor
-
Kuratomi, G., Komuro, A., Goto, K., Shinozaki, M., Miyazawa, K., Miyazono, K. and Imamura, T. (2005) NEDD4-NEDD2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-β (transforming growth factor-β) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-β type I receptor. Biochem. J. 386, 461-470
-
(2005)
Biochem. J.
, vol.386
, pp. 461-470
-
-
Kuratomi, G.1
Komuro, A.2
Goto, K.3
Shinozaki, M.4
Miyazawa, K.5
Miyazono, K.6
Imamura, T.7
-
41
-
-
70350785179
-
Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-β signaling
-
Gao, S., Alarcon, C., Sapkota, G., Rahman, S., Chen, P. Y., Goerner, N., Macias, M. J., Erdjument-Bromage, H., Tempst, P. and Massague, J. (2009) Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-β signaling. Mol. Cell 36, 457-468
-
(2009)
Mol. Cell
, vol.36
, pp. 457-468
-
-
Gao, S.1
Alarcon, C.2
Sapkota, G.3
Rahman, S.4
Chen, P.Y.5
Goerner, N.6
Macias, M.J.7
Erdjument-Bromage, H.8
Tempst, P.9
Massague, J.10
-
42
-
-
0034767430
-
Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins
-
Fukuchi, M., Imamura, T., Chiba, T., Ebisawa, T., Kawabata, M., Tanaka, K. and Miyazono, K. (2001) Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins. Mol. Biol. Cell 12, 1431-1443
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1431-1443
-
-
Fukuchi, M.1
Imamura, T.2
Chiba, T.3
Ebisawa, T.4
Kawabata, M.5
Tanaka, K.6
Miyazono, K.7
-
43
-
-
20144385807
-
CHIP controls the sensitivity of transforming growth factor-β signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation
-
Xin, H., Xu, X., Li, L., Ning, H., Rong, Y., Shang, Y., Wang, Y., Fu, X. Y. and Chang, Z. (2005) CHIP controls the sensitivity of transforming growth factor-β signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation. J. Biol. Chem. 280, 20842-20850
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20842-20850
-
-
Xin, H.1
Xu, X.2
Li, L.3
Ning, H.4
Rong, Y.5
Shang, Y.6
Wang, Y.7
Fu, X.Y.8
Chang, Z.9
-
44
-
-
0347986662
-
CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription
-
Li, L., Xin, H., Xu, X., Huang, M., Zhang, X., Chen, Y., Zhang, S., Fu, X. Y. and Chang, Z. (2004) CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription. Mol. Cell. Biol. 24, 856-864
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 856-864
-
-
Li, L.1
Xin, H.2
Xu, X.3
Huang, M.4
Zhang, X.5
Chen, Y.6
Zhang, S.7
Fu, X.Y.8
Chang, Z.9
-
45
-
-
4344619927
-
Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2
-
Liang, M., Liang, Y. Y., Wrighton, K., Ungermannova, D., Wang, X. P., Brunicardi, F. C., Liu, X., Feng, X. H. and Lin, X. (2004) Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2. Mol. Cell. Biol. 24, 7524-7537
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7524-7537
-
-
Liang, M.1
Liang, Y.Y.2
Wrighton, K.3
Ungermannova, D.4
Wang, X.P.5
Brunicardi, F.C.6
Liu, X.7
Feng, X.H.8
Lin, X.9
-
46
-
-
0036198412
-
Jab1 antagonizes TGF-β signaling by inducing Smad4 degradation
-
Wan, M., Cao, X., Wu, Y., Bai, S., Wu, L., Shi, X. and Wang, N. (2002) Jab1 antagonizes TGF-β signaling by inducing Smad4 degradation. EMBO Rep. 3, 171-176
-
(2002)
EMBO Rep.
, vol.3
, pp. 171-176
-
-
Wan, M.1
Cao, X.2
Wu, Y.3
Bai, S.4
Wu, L.5
Shi, X.6
Wang, N.7
-
47
-
-
20444439172
-
Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases
-
Moren, A., Imamura, T., Miyazono, K., Heldin, C. H. and Moustakas, A. (2005) Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases. J. Biol. Chem. 280, 22115-22123
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 22115-22123
-
-
Moren, A.1
Imamura, T.2
Miyazono, K.3
Heldin, C.H.4
Moustakas, A.5
-
48
-
-
0042858169
-
Differential ubiquitination defines the functional status of the tumor suppressor Smad4
-
Moren, A., Hellman, U., Inada, Y., Imamura, T., Heldin, C. H. and Moustakas, A. (2003) Differential ubiquitination defines the functional status of the tumor suppressor Smad4. J. Biol. Chem. 278, 33571-33582
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33571-33582
-
-
Moren, A.1
Hellman, U.2
Inada, Y.3
Imamura, T.4
Heldin, C.H.5
Moustakas, A.6
-
49
-
-
58149093172
-
FAM/USP9x, a deubiquitinating enzyme essential for TGFβ signaling, controls Smad4 monoubiquitination
-
Dupont, S., Mamidi, A., Cordenonsi, M., Montagner, M., Zacchigna, L., Adorno, M., Martello, G., Stinchfield, M. J., Soligo, S., Morsut, L. et al. (2009) FAM/USP9x, a deubiquitinating enzyme essential for TGFβ signaling, controls Smad4 monoubiquitination. Cell 136, 123-135
-
(2009)
Cell
, vol.136
, pp. 123-135
-
-
Dupont, S.1
Mamidi, A.2
Cordenonsi, M.3
Montagner, M.4
Zacchigna, L.5
Adorno, M.6
Martello, G.7
Stinchfield, M.J.8
Soligo, S.9
Morsut, L.10
-
50
-
-
0037805684
-
Activation of transforming growth factor-β signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4
-
Lin, X., Liang, M., Liang, Y. Y., Brunicardi, F. C., Melchior, F. and Feng, X. H. (2003) Activation of transforming growth factor-β signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4. J. Biol. Chem. 278, 18714-18719
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18714-18719
-
-
Lin, X.1
Liang, M.2
Liang, Y.Y.3
Brunicardi, F.C.4
Melchior, F.5
Feng, X.H.6
-
51
-
-
0042867243
-
Sumoylation of Smad4, the common Smad mediator of transforming growth factor-β family signaling
-
Lee, P. S., Chang, C., Liu, D. and Derynck, R. (2003) Sumoylation of Smad4, the common Smad mediator of transforming growth factor-β family signaling. J. Biol. Chem. 278, 27853-27863
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27853-27863
-
-
Lee, P.S.1
Chang, C.2
Liu, D.3
Derynck, R.4
-
52
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
-
Ebisawa, T., Fukuchi, M., Murakami, G., Chiba, T., Tanaka, K., Imamura, T. and Miyazono, K. (2001) Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation. J. Biol. Chem. 276, 12477-12480
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, G.3
Chiba, T.4
Tanaka, K.5
Imamura, T.6
Miyazono, K.7
-
53
-
-
0038363366
-
Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-β signaling by Smad7
-
Tajima, Y., Goto, K., Yoshida, M., Shinomiya, K., Sekimoto, T., Yoneda, Y., Miyazono, K. and Imamura, T. (2003) Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-β signaling by Smad7. J. Biol. Chem. 278, 10716-10721
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10716-10721
-
-
Tajima, Y.1
Goto, K.2
Yoshida, M.3
Shinomiya, K.4
Sekimoto, T.5
Yoneda, Y.6
Miyazono, K.7
Imamura, T.8
-
54
-
-
0032582672
-
Transforming growth factor β1 induces nuclear export of inhibitory Smad7
-
Itoh, S., Landstrom, M., Hermansson, A., Itoh, F., Heldin, C. H., Heldin, N. E. and ten Dijke, P. (1998) Transforming growth factor β1 induces nuclear export of inhibitory Smad7. J. Biol. Chem. 273, 29195-29201
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29195-29201
-
-
Itoh, S.1
Landstrom, M.2
Hermansson, A.3
Itoh, F.4
Heldin, C.H.5
Heldin, N.E.6
Ten Dijke, P.7
-
55
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF β receptor for degradation
-
Kavsak, P., Rasmussen, R. K., Causing, C. G., Bonni, S., Zhu, H., Thomsen, G. H. and Wrana, J. L. (2000) Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF β receptor for degradation. Mol. Cell 6, 1365-1375
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
56
-
-
0037131283
-
Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane
-
Suzuki, C., Murakami, G., Fukuchi, M., Shimanuki, T., Shikauchi, Y., Imamura, T. and Miyazono, K. (2002) Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane. J. Biol. Chem. 277, 39919-39925
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39919-39925
-
-
Suzuki, C.1
Murakami, G.2
Fukuchi, M.3
Shimanuki, T.4
Shikauchi, Y.5
Imamura, T.6
Miyazono, K.7
-
57
-
-
48249099342
-
Critical regulation of TGFβ signaling by Hsp90
-
Wrighton, K. H., Lin, X. and Feng, X. H. (2008) Critical regulation of TGFβ signaling by Hsp90. Proc. Natl. Acad. Sci. U.S.A. 105, 9244-9249
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 9244-9249
-
-
Wrighton, K.H.1
Lin, X.2
Feng, X.H.3
-
58
-
-
0036753547
-
Control of Smad7 stability by competition between acetylation and ubiquitination
-
DOI 10.1016/S1097-2765(02)00639-1
-
Gronroos, E., Hellman, U., Heldin, C. H. and Ericsson, J. (2002) Control of Smad7 stability by competition between acetylation and ubiquitination. Mol. Cell 10, 483-493 (Pubitemid 35284169)
-
(2002)
Molecular Cell
, vol.10
, Issue.3
, pp. 483-493
-
-
Gronroos, E.1
Hellman, U.2
Heldin, C.-H.3
Ericsson, J.4
-
59
-
-
20444474176
-
The balance between acetylation and deacetylation controls Smad7 stability
-
Simonsson, M., Heldin, C. H., Ericsson, J. and Gronroos, E. (2005) The balance between acetylation and deacetylation controls Smad7 stability. J. Biol. Chem. 280, 21797-21803
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 21797-21803
-
-
Simonsson, M.1
Heldin, C.H.2
Ericsson, J.3
Gronroos, E.4
-
60
-
-
2942581416
-
Protein tyrosine phosphatases in the human genome
-
DOI 10.1016/j.cell.2004.05.018, PII S0092867404005343
-
Alonso, A., Sasin, J., Bottini, N., Friedberg, I., Osterman, A., Godzik, A., Hunter, T., Dixon, J. and Mustelin, T. (2004) Protein tyrosine phosphatases in the human genome. Cell 117, 699-711 (Pubitemid 38748887)
-
(2004)
Cell
, vol.117
, Issue.6
, pp. 699-711
-
-
Alonso, A.1
Sasin, J.2
Bottini, N.3
Friedberg, I.4
Friedberg, I.5
Osterman, A.6
Godzik, A.7
Hunter, T.8
Dixon, J.9
Mustelin, T.10
-
61
-
-
15044348175
-
Protein serine/threonine phosphatases: Life, death, and sleeping
-
Gallego, M. and Virshup, D. M. (2005) Protein serine/threonine phosphatases: life, death, and sleeping. Curr. Opin. Cell Biol. 17, 197-202
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, pp. 197-202
-
-
Gallego, M.1
Virshup, D.M.2
-
62
-
-
70350340056
-
Serine/threonine phosphatases: Mechanism through structure
-
Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell 139, 468-484
-
(2009)
Cell
, vol.139
, pp. 468-484
-
-
Shi, Y.1
-
63
-
-
0035489955
-
Control of RNA polymerase II activity by dedicated CTD kinases and phosphatases
-
Majello, B. and Napolitano, G. (2001) Control of RNA polymerase II activity by dedicated CTD kinases and phosphatases. Front. Biosci. 6, D1358-D1368
-
(2001)
Front. Biosci.
, vol.6
-
-
Majello, B.1
Napolitano, G.2
-
64
-
-
0036699073
-
PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster
-
Bennett, D. and Alphey, L. (2002) PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster. Nat. Genet. 31, 419-423
-
(2002)
Nat. Genet.
, vol.31
, pp. 419-423
-
-
Bennett, D.1
Alphey, L.2
-
65
-
-
1642539976
-
GADD34-PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor
-
Shi, W., Sun, C., He, B., Xiong, W., Shi, X., Yao, D. and Cao, X. (2004) GADD34-PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor. J. Cell Biol. 164, 291-300
-
(2004)
J. Cell Biol.
, vol.164
, pp. 291-300
-
-
Shi, W.1
Sun, C.2
He, B.3
Xiong, W.4
Shi, X.5
Yao, D.6
Cao, X.7
-
66
-
-
53349156578
-
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-β/Activin/Nodal signalling
-
Batut, J., Schmierer, B., Cao, J., Raftery, L. A., Hill, C. S. and Howell, M. (2008) Two highly related regulatory subunits of PP2A exert opposite effects on TGF-β/Activin/Nodal signalling. Development 135, 2927-2937
-
(2008)
Development
, vol.135
, pp. 2927-2937
-
-
Batut, J.1
Schmierer, B.2
Cao, J.3
Raftery, L.A.4
Hill, C.S.5
Howell, M.6
-
68
-
-
0031741865
-
Physical and functional interactions between type I transforming growth factor β receptors and Bα, a WD-40 repeat subunit of phosphatase 2A
-
Griswold-Prenner, I., Kamibayashi, C., Maruoka, E. M., Mumby, M. C. and Derynck, R. (1998) Physical and functional interactions between type I transforming growth factor β receptors and Bα, a WD-40 repeat subunit of phosphatase 2A. Mol. Cell. Biol. 18, 6595-6604
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6595-6604
-
-
Griswold-Prenner, I.1
Kamibayashi, C.2
Maruoka, E.M.3
Mumby, M.C.4
Derynck, R.5
-
69
-
-
77950471243
-
Hypoxia-activated Smad3-specific dephosphorylation by PP2A
-
Heikkinen, P. T., Nummela, M., Leivonen, S. K., Westermarck, J., Hill, C. S., Kahari, V. M. and Jaakkola, P. M. (2010) Hypoxia-activated Smad3-specific dephosphorylation by PP2A. J. Biol. Chem. 285, 3740-3749
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 3740-3749
-
-
Heikkinen, P.T.1
Nummela, M.2
Leivonen, S.K.3
Westermarck, J.4
Hill, C.S.5
Kahari, V.M.6
Jaakkola, P.M.7
-
70
-
-
0036670339
-
Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-β receptor activity
-
Inman, G. J., Nicolas, F. J. and Hill, C. S. (2002) Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-β receptor activity. Mol. Cell 10, 283-294
-
(2002)
Mol. Cell
, vol.10
, pp. 283-294
-
-
Inman, G.J.1
Nicolas, F.J.2
Hill, C.S.3
-
71
-
-
27644583784
-
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads
-
Schmierer, B. and Hill, C. S. (2005) Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads. Mol. Cell. Biol. 25, 9845-9858
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9845-9858
-
-
Schmierer, B.1
Hill, C.S.2
-
72
-
-
0036670359
-
Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFβ signaling complexes in the cytoplasm and nucleus
-
Xu, L., Kang, Y., Col, S. and Massague, J. (2002) Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFβ signaling complexes in the cytoplasm and nucleus. Mol. Cell 10, 271-282
-
(2002)
Mol. Cell
, vol.10
, pp. 271-282
-
-
Xu, L.1
Kang, Y.2
Col, S.3
Massague, J.4
-
73
-
-
33947617324
-
Termination of TGF-β superfamily signaling through SMAD dephosphorylation: A functional genomic view
-
Lin, X., Chen, Y., Meng, A. and Feng, X. (2007) Termination of TGF-β superfamily signaling through SMAD dephosphorylation: a functional genomic view. J. Genet. Genomics 34, 1-9
-
(2007)
J. Genet. Genomics
, vol.34
, pp. 1-9
-
-
Lin, X.1
Chen, Y.2
Meng, A.3
Feng, X.4
-
74
-
-
33646950265
-
PPM1A functions as a Smad phosphatase to terminate TGFβ signaling
-
Lin, X., Duan, X., Liang, Y. Y., Su, Y., Wrighton, K. H., Long, J., Hu, M., Davis, C. M., Wang, J., Brunicardi, F. C. et al. (2006) PPM1A functions as a Smad phosphatase to terminate TGFβ signaling. Cell 125, 915-928
-
(2006)
Cell
, vol.125
, pp. 915-928
-
-
Lin, X.1
Duan, X.2
Liang, Y.Y.3
Su, Y.4
Wrighton, K.H.5
Long, J.6
Hu, M.7
Davis, C.M.8
Wang, J.9
Brunicardi, F.C.10
-
75
-
-
61749096309
-
Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-β signaling
-
Dai, F., Lin, X., Chang, C. and Feng, X. H. (2009) Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-β signaling. Dev. Cell 16, 345-357
-
(2009)
Dev. Cell
, vol.16
, pp. 345-357
-
-
Dai, F.1
Lin, X.2
Chang, C.3
Feng, X.H.4
-
76
-
-
77950874802
-
MTMR4 attenuates TGFβ signaling by dephosphorylating R-Smads in endosomes
-
Yu, J., Pan, L., Qin, X., Chen, H., Xu, Y., Chen, Y. and Tang, H. (2010) MTMR4 attenuates TGFβ signaling by dephosphorylating R-Smads in endosomes. J. Biol. Chem. 285, 8454-8462
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 8454-8462
-
-
Yu, J.1
Pan, L.2
Qin, X.3
Chen, H.4
Xu, Y.5
Chen, Y.6
Tang, H.7
-
77
-
-
33846002754
-
Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway
-
Duan, X., Liang, Y. Y., Feng, X. H. and Lin, X. (2006) Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway. J. Biol. Chem. 281, 36526-36532
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36526-36532
-
-
Duan, X.1
Liang, Y.Y.2
Feng, X.H.3
Lin, X.4
-
78
-
-
33747044916
-
Unique players in the BMP pathway: Small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling
-
Knockaert, M., Sapkota, G., Alarcon, C., Massague, J. and Brivanlou, A. H. (2006) Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling. Proc. Natl. Acad. Sci. U.S.A. 103, 11940-11945
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 11940-11945
-
-
Knockaert, M.1
Sapkota, G.2
Alarcon, C.3
Massague, J.4
Brivanlou, A.H.5
-
79
-
-
33644996932
-
Identification of phosphatases for Smad in the BMP/DPP pathway
-
Chen, H. B., Shen, J., Ip, Y. T. and Xu, L. (2006) Identification of phosphatases for Smad in the BMP/DPP pathway. Genes Dev. 20, 648-653
-
(2006)
Genes Dev.
, vol.20
, pp. 648-653
-
-
Chen, H.B.1
Shen, J.2
Ip, Y.T.3
Xu, L.4
-
80
-
-
24944497786
-
Non-Smad TGF-β signals
-
Moustakas, A. and Heldin, C. H. (2005) Non-Smad TGF-β signals. J. Cell Sci. 118, 3573-3584
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
81
-
-
3142546336
-
Cyclin-dependent kinases regulate the antiproliferative function of Smads
-
Matsuura, I., Denissova, N. G., Wang, G., He, D., Long, J. and Liu, F. (2004) Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature 430, 226-231
-
(2004)
Nature
, vol.430
, pp. 226-231
-
-
Matsuura, I.1
Denissova, N.G.2
Wang, G.3
He, D.4
Long, J.5
Liu, F.6
-
82
-
-
0033106484
-
A mechanism of repression of TGFβ/ Smad signaling by oncogenic Ras
-
Kretzschmar, M., Doody, J., Timokhina, I. and Massague, J. (1999) A mechanism of repression of TGFβ/ Smad signaling by oncogenic Ras. Genes Dev. 13, 804-816
-
(1999)
Genes Dev.
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massague, J.4
-
83
-
-
0036829567
-
Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase
-
Funaba, M., Zimmerman, C. M. and Mathews, L. S. (2002) Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase. J. Biol. Chem. 277, 41361-41368
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41361-41368
-
-
Funaba, M.1
Zimmerman, C.M.2
Mathews, L.S.3
-
84
-
-
0033601179
-
Interdependent SMAD and JNK signaling in transforming growth factor-β-mediated transcription
-
Engel, M. E., McDonnell, M. A., Law, B. K. and Moses, H. L. (1999) Interdependent SMAD and JNK signaling in transforming growth factor-β-mediated transcription. J. Biol. Chem. 274, 37413-37420
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37413-37420
-
-
Engel, M.E.1
McDonnell, M.A.2
Law, B.K.3
Moses, H.L.4
-
85
-
-
6044261233
-
TGF-β and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions
-
Mori, S., Matsuzaki, K., Yoshida, K., Furukawa, F., Tahashi, Y., Yamagata, H., Sekimoto, G., Seki, T., Matsui, H., Nishizawa, M. et al. (2004) TGF-β and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions. Oncogene 23, 7416-7429
-
(2004)
Oncogene
, vol.23
, pp. 7416-7429
-
-
Mori, S.1
Matsuzaki, K.2
Yoshida, K.3
Furukawa, F.4
Tahashi, Y.5
Yamagata, H.6
Sekimoto, G.7
Seki, T.8
Matsui, H.9
Nishizawa, M.10
-
86
-
-
12544257249
-
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-β-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo
-
Kamaraju, A. K. and Roberts, A. B. (2005) Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-β-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo. J. Biol. Chem. 280, 1024-1036
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1024-1036
-
-
Kamaraju, A.K.1
Roberts, A.B.2
-
87
-
-
19944429743
-
2-terminal kinase during human colorectal carcinogenesis
-
2- terminal kinase during human colorectal carcinogenesis. Cancer Res. 65, 157-165
-
(2005)
Cancer Res.
, vol.65
, pp. 157-165
-
-
Yamagata, H.1
Matsuzaki, K.2
Mori, S.3
Yoshida, K.4
Tahashi, Y.5
Furukawa, F.6
Sekimoto, G.7
Watanabe, T.8
Uemura, Y.9
Sakaida, N.10
-
88
-
-
46849092804
-
To (TGF)β or not to (TGF)β: Fine-tuning of Smad signaling via post-translational modifications
-
Wrighton, K. H. and Feng, X. H. (2008) To (TGF)β or not to (TGF)β: fine-tuning of Smad signaling via post-translational modifications. Cell. Signalling 20, 1579-1591
-
(2008)
Cell. Signalling
, vol.20
, pp. 1579-1591
-
-
Wrighton, K.H.1
Feng, X.H.2
-
89
-
-
58149239730
-
Phospho-control of TGF-β superfamily signaling
-
Wrighton, K. H., Lin, X. and Feng, X. H. (2009) Phospho-control of TGF-β superfamily signaling. Cell. Res. 19, 8-20
-
(2009)
Cell. Res.
, vol.19
, pp. 8-20
-
-
Wrighton, K.H.1
Lin, X.2
Feng, X.H.3
-
90
-
-
0030773834
-
Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1
-
Kretzschmar, M., Doody, J. and Massague, J. (1997) Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1. Nature 389, 618-622
-
(1997)
Nature
, vol.389
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massague, J.3
-
91
-
-
2942650916
-
In vivo convergence of BMP and MAPK signaling pathways: Impact of differential Smad1 phosphorylation on development and homeostasis
-
Aubin, J., Davy, A. and Soriano, P. (2004) In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis. Genes Dev. 18, 1482-1494
-
(2004)
Genes Dev.
, vol.18
, pp. 1482-1494
-
-
Aubin, J.1
Davy, A.2
Soriano, P.3
-
92
-
-
33846688094
-
Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker
-
DOI 10.1016/j.molcel.2007.01.006, PII S109727650700010X
-
Sapkota, G., Alarcon, C., Spagnoli, F. M., Brivanlou, A. H. and Massague, J. (2007) Balancing BMP signaling through integrated inputs into the Smad1 linker. Mol. Cell 25, 441-454 (Pubitemid 46199289)
-
(2007)
Molecular Cell
, vol.25
, Issue.3
, pp. 441-454
-
-
Sapkota, G.1
Alarcon, C.2
Spagnoli, F.M.3
Brivanlou, A.H.4
Massague, J.5
-
93
-
-
36248995245
-
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
-
Fuentealba, L. C., Eivers, E., Ikeda, A., Hurtado, C., Kuroda, H., Pera, E. M. and De Robertis, E. M. (2007) Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 131, 980-993
-
(2007)
Cell
, vol.131
, pp. 980-993
-
-
Fuentealba, L.C.1
Eivers, E.2
Ikeda, A.3
Hurtado, C.4
Kuroda, H.5
Pera, E.M.6
De Robertis, E.M.7
-
94
-
-
33846028557
-
Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-β signaling
-
Wrighton, K. H., Willis, D., Long, J., Liu, F., Lin, X. and Feng, X. H. (2006) Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-β signaling. J. Biol. Chem. 281, 38365-38375
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 38365-38375
-
-
Wrighton, K.H.1
Willis, D.2
Long, J.3
Liu, F.4
Lin, X.5
Feng, X.H.6
-
95
-
-
33845970267
-
Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-β pathways
-
Sapkota, G., Knockaert, M., Alarcon, C., Montalvo, E., Brivanlou, A. H. and Massague, J. (2006) Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-β pathways. J. Biol. Chem. 281, 40412-40419
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 40412-40419
-
-
Sapkota, G.1
Knockaert, M.2
Alarcon, C.3
Montalvo, E.4
Brivanlou, A.H.5
Massague, J.6
|