-
1
-
-
0346254671
-
New class of transforming growth factors potentiated by epidermal growth factor: Isolation from non-neoplastic tissues
-
A. B. Roberts, M. A. Anzano, L. C. Lamb, J. M. Smith, M. B. Sporn, New class of transforming growth factors potentiated by epidermal growth factor: Isolation from non-neoplastic tissues. Proc. Natl. Acad. Sci. U.S.A. 78, 5339-5343 (1981).
-
(1981)
Proc. Natl. Acad. Sci. U.S.A.
, vol.78
, pp. 5339-5343
-
-
Roberts, A.B.1
Anzano, M.A.2
Lamb, L.C.3
Smith, J.M.4
Sporn, M.B.5
-
2
-
-
0031685620
-
TGF-β signal transduction
-
J. Massague, TGF-β signal transduction. Annu. Rev. Biochem. 67, 753-791 (1998).
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
3
-
-
0028180315
-
The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
-
D. M. Kingsley, The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8, 133-146 (1994).
-
(1994)
Genes Dev.
, vol.8
, pp. 133-146
-
-
Kingsley, D.M.1
-
4
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
C. H. Heldin, K. Miyazono, P. ten Dijke, TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471 (1997).
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
5
-
-
0036888335
-
Integration of the TGF-β pathway into the cellular signalling network
-
M. Lutz, P. Knaus, Integration of the TGF-β pathway into the cellular signalling network. Cell. Signal. 14, 977-988 (2002).
-
(2002)
Cell. Signal
, vol.14
, pp. 977-988
-
-
Lutz, M.1
Knaus, P.2
-
6
-
-
21244479759
-
Fine tuning and cross-talking of TGF-β signal by inhibitory Smads
-
S. H. Park, Fine tuning and cross-talking of TGF-β signal by inhibitory Smads. J. Biochem. Mol. Biol. 38, 9-16 (2005).
-
(2005)
J. Biochem. Mol. Biol.
, vol.38
, pp. 9-16
-
-
Park, S.H.1
-
7
-
-
23044466047
-
Specificity and versatility in TGF-β signaling through Smads
-
X. H. Feng, R. Derynck, Specificity and versatility in TGF-β signaling through Smads. Annu. Rev. Cell Dev. Biol. 21, 659-693 (2005).
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
8
-
-
0024419833
-
Transforming growth factor-β regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts
-
A. Kimura, O. Katoh, H. Hyodo, A. Kuramoto, Transforming growth factor-β regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts. Br. J. Haematol. 72, 486-491 (1989).
-
(1989)
Br. J. Haematol.
, vol.72
, pp. 486-491
-
-
Kimura, A.1
Katoh, O.2
Hyodo, H.3
Kuramoto, A.4
-
9
-
-
0029616117
-
Cell type-specific modulation of cell growth by transforming growth factor β 1 does not correlate with mitogen-activated protein kinase activation
-
Y. Chatani, S. Tanimura, N. Miyoshi, A. Hattori, M. Sato, M. Kohno, Cell type-specific modulation of cell growth by transforming growth factor β 1 does not correlate with mitogen-activated protein kinase activation. J. Biol. Chem. 270, 30686-30692 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 30686-30692
-
-
Chatani, Y.1
Tanimura, S.2
Miyoshi, N.3
Hattori, A.4
Sato, M.5
Kohno, M.6
-
10
-
-
0034104591
-
Smads as transcriptional co-modulators
-
L. Attisano, J. L. Wrana, Smads as transcriptional co-modulators. Curr. Opin. Cell Biol. 12, 235-243 (2000).
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 235-243
-
-
Attisano, L.1
Wrana, J.L.2
-
11
-
-
28944444185
-
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells
-
H. Azuma, S. Ehata, H. Miyazaki, T. Watabe, O. Maruyama, T. Imamura, T. Sakamoto, S. Kiyama, Y. Kiyama, T. Ubai, T. Inamoto, S. Takahara, Y. Itoh, Y. Otsuki, Y. Katsuoka, K. Miyazono, S. Horie, Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells. J. Natl. Cancer Inst. 97, 1734-1746 (2005).
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 1734-1746
-
-
Azuma, H.1
Ehata, S.2
Miyazaki, H.3
Watabe, T.4
Maruyama, O.5
Imamura, T.6
Sakamoto, T.7
Kiyama, S.8
Kiyama, Y.9
Ubai, T.10
Inamoto, T.11
Takahara, S.12
Itoh, Y.13
Otsuki, Y.14
Katsuoka, Y.15
Miyazono, K.16
Horie, S.17
-
12
-
-
27844514155
-
Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo
-
D. Javelaud, V. Delmas, M. Moller, P. Sextius, J. Andre, S. Menashi, L. Larue, A. Mauviel, Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo. Oncogene 24, 7624-7629 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 7624-7629
-
-
Javelaud, D.1
Delmas, V.2
Moller, M.3
Sextius, P.4
Andre, J.5
Menashi, S.6
Larue, L.7
Mauviel, A.8
-
13
-
-
33947265488
-
Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis
-
D. Javelaud, K. S. Mohammad, C. R. McKenna, P. Fournier, F. Luciani, M. Niewolna, J. Andre, V. Delmas, L. Larue, T. A. Guise, A. Mauviel, Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis. Cancer Res. 67, 2317-2324 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 2317-2324
-
-
Javelaud, D.1
Mohammad, K.S.2
McKenna, C.R.3
Fournier, P.4
Luciani, F.5
Niewolna, M.6
Andre, J.7
Delmas, V.8
Larue, L.9
Guise, T.A.10
Mauviel, A.11
-
14
-
-
0345275872
-
Smad7 but not Smad6 cooperates with oncogenic ras to cause malignant conversion in a mouse model for squamous cell carcinoma
-
X. Liu, J. Lee, M. Cooley, E. Bhogte, S. Hartley, A. Glick, Smad7 but not Smad6 cooperates with oncogenic ras to cause malignant conversion in a mouse model for squamous cell carcinoma. Cancer Res. 63, 7760-7768 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 7760-7768
-
-
Liu, X.1
Lee, J.2
Cooley, M.3
Bhogte, E.4
Hartley, S.5
Glick, A.6
-
15
-
-
51449104812
-
Smad7 induces hepatic metastasis in colorectal cancer
-
S. K. Halder, G. Rachakonda, N. G. Deane, P. K. Datta, Smad7 induces hepatic metastasis in colorectal cancer. Br. J. Cancer 99, 957-965 (2008).
-
(2008)
Br. J. Cancer
, vol.99
, pp. 957-965
-
-
Halder, S.K.1
Rachakonda, G.2
Deane, N.G.3
Datta, P.K.4
-
16
-
-
19544368435
-
Smad7 induces tumorigenicity by blocking TGF-β-induced growth inhibition and apoptosis
-
S. K. Halder, R. D. Beauchamp, P. K. Datta, Smad7 induces tumorigenicity by blocking TGF-β-induced growth inhibition and apoptosis. Exp. Cell Res. 307, 231-246 (2005).
-
(2005)
Exp. Cell Res.
, vol.307
, pp. 231-246
-
-
Halder, S.K.1
Beauchamp, R.D.2
Datta, P.K.3
-
17
-
-
16344378397
-
TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
-
U. Valcourt, M. Kowanetz, H. Niimi, C. H. Heldin, A. Moustakas, TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Mol. Biol. Cell 16, 1987-2002 (2005).
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 1987-2002
-
-
Valcourt, U.1
Kowanetz, M.2
Niimi, H.3
Heldin, C.H.4
Moustakas, A.5
-
18
-
-
53049085564
-
Smad7 stabilizes β-catenin binding to E-cadherin complex and promotes cell-cell adhesion
-
Y. Tang, Z. Liu, L. Zhao, T. L. Clemens, X. Cao, Smad7 stabilizes β-catenin binding to E-cadherin complex and promotes cell-cell adhesion. J. Biol. Chem. 283, 23956-23963 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 23956-23963
-
-
Tang, Y.1
Liu, Z.2
Zhao, L.3
Clemens, T.L.4
Cao, X.5
-
19
-
-
0141557542
-
Regulation of transforming growth factor-β signaling by protein inhibitor of activated STAT, PIASy through Smad3
-
S. Imoto, K. Sugiyama, R. Muromoto, N. Sato, T. Yamamoto, T. Matsuda, Regulation of transforming growth factor-β signaling by protein inhibitor of activated STAT, PIASy through Smad3. J. Biol. Chem. 278, 34253-34258 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34253-34258
-
-
Imoto, S.1
Sugiyama, K.2
Muromoto, R.3
Sato, N.4
Yamamoto, T.5
Matsuda, T.6
-
20
-
-
84890053819
-
-
and http://phospho.elm.eu.org
-
http://www.thebiogrid.org and http://phospho.elm.eu.org
-
-
-
-
21
-
-
0344926331
-
Identification of novel Smad binding proteins
-
D. R. Warner, E. A. Roberts, R. M. Greene, M. M. Pisano, Identification of novel Smad binding proteins. Biochem. Biophys. Res. Commun. 312, 1185-1190 (2003).
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.312
, pp. 1185-1190
-
-
Warner, D.R.1
Roberts, E.A.2
Greene, R.M.3
Pisano, M.M.4
-
22
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
B. N. Davis, A. C. Hilyard, G. Lagna, A. Hata, SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454, 56-61 (2008).
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
23
-
-
41749113108
-
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
-
I. A. Asangani, S. A. Rasheed, D. A. Nikolova, J. H. Leupold, N. H. Colburn, S. Post, H. Allgayer, MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27, 2128-2136 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 2128-2136
-
-
Asangani, I.A.1
Rasheed, S.A.2
Nikolova, D.A.3
Leupold, J.H.4
Colburn, N.H.5
Post, S.6
Allgayer, H.7
-
24
-
-
38149042783
-
Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
-
L. B. Frankel, N. R. Christoffersen, A. Jacobsen, M. Lindow, A. Krogh, A. H. Lund, Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem. 283, 1026-1033 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1026-1033
-
-
Frankel, L.B.1
Christoffersen, N.R.2
Jacobsen, A.3
Lindow, M.4
Krogh, A.5
Lund, A.H.6
-
25
-
-
40249092910
-
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
-
S. Zhu, H. Wu, F. Wu, D. Nie, S. Sheng, Y. Y. Mo, MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res. 18, 350-359 (2008).
-
(2008)
Cell Res.
, vol.18
, pp. 350-359
-
-
Zhu, S.1
Wu, H.2
Wu, F.3
Nie, D.4
Sheng, S.5
Mo, Y.Y.6
-
26
-
-
27644583784
-
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads
-
B. Schmierer, C. S. Hill, Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads. Mol. Cell. Biol. 25, 9845-9858 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9845-9858
-
-
Schmierer, B.1
Hill, C.S.2
-
27
-
-
0034023371
-
Functions of mammalian Smad genes as revealed by targeted gene disruption in mice
-
M. Weinstein, X. Yang, C. Deng, Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. Cytokine Growth Factor Rev. 11, 49-58 (2000).
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 49-58
-
-
Weinstein, M.1
Yang, X.2
Deng, C.3
-
28
-
-
2642605344
-
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
-
M. P. de Caestecker, W. T. Parks, C. J. Frank, P. Castagnino, D. P. Bottaro, A. B. Roberts, R. J. Lechleider, Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev. 12, 1587-1592 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 1587-1592
-
-
De Caestecker, M.P.1
Parks, W.T.2
Frank, C.J.3
Castagnino, P.4
Bottaro, D.P.5
Roberts, A.B.6
Lechleider, R.J.7
-
29
-
-
0033969934
-
Microtubule binding to Smads may regulate TGF β activity
-
C. Dong, Z. Li, R. Alvarez Jr., X. H. Feng, P. J. Goldschmidt-Clermont, Microtubule binding to Smads may regulate TGF β activity. Mol. Cell 5, 27-34 (2000).
-
(2000)
Mol. Cell
, vol.5
, pp. 27-34
-
-
Dong, C.1
Li, Z.2
Alvarez Jr., R.3
Feng, X.H.4
Goldschmidt-Clermont, P.J.5
-
30
-
-
34547108860
-
Activation of Mps1 promotes transforming growth factor-β- independent Smad signaling
-
S. Zhu, W. Wang, D. C. Clarke, X. Liu, Activation of Mps1 promotes transforming growth factor-β- independent Smad signaling. J. Biol. Chem. 282, 18327-18338 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 18327-18338
-
-
Zhu, S.1
Wang, W.2
Clarke, D.C.3
Liu, X.4
-
31
-
-
55049117137
-
Retinoids regulate TGFβ signaling at the level of Smad2 phosphorylation and nuclear accumulation
-
L. L. Hoover, E. G. Burton, M. L. O'Neill, B. A. Brooks, S. Sreedharan, N. A. Dawson, S. W. Kubalak, Retinoids regulate TGFβ signaling at the level of Smad2 phosphorylation and nuclear accumulation. Biochim. Biophys. Acta 1783, 2279-2286 (2008).
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 2279-2286
-
-
Hoover, L.L.1
Burton, E.G.2
O'neill, M.L.3
Brooks, B.A.4
Sreedharan, S.5
Dawson, N.A.6
Kubalak, S.W.7
-
32
-
-
0026682845
-
Interactions between retinoids and TGF β s in mouse morphogenesis
-
R. Mahmood, K. C. Flanders, G. M. Morriss-Kay, Interactions between retinoids and TGF β s in mouse morphogenesis. Development 115, 67-74 (1992).
-
(1992)
Development
, vol.115
, pp. 67-74
-
-
Mahmood, R.1
Flanders, K.C.2
Morriss-Kay, G.M.3
-
33
-
-
30144440756
-
All-trans retinoic acid inhibited chondrogenesis of mouse embryonic palate mesenchymal cells by down-regulation of TGF-β/Smad signaling
-
Z. Yu, Y. Xing, All-trans retinoic acid inhibited chondrogenesis of mouse embryonic palate mesenchymal cells by down-regulation of TGF-β/Smad signaling. Biochem. Biophys. Res. Commun. 340, 929-934 (2006).
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.340
, pp. 929-934
-
-
Yu, Z.1
Xing, Y.2
-
34
-
-
0025506964
-
TGF-β and retinoic acid: Regulators of growth and modifiers of differentiation in human epidermal cells
-
Y. Choi, E. Fuchs, TGF-β and retinoic acid: Regulators of growth and modifiers of differentiation in human epidermal cells. Cell Regul. 1, 791-809 (1990).
-
(1990)
Cell Regul.
, vol.1
, pp. 791-809
-
-
Choi, Y.1
Fuchs, E.2
-
35
-
-
39549116113
-
On the role of transforming growth factor-β in the growth inhibitory effects of retinoic acid in human pancreatic cancer cells
-
B. Singh, R. F. Murphy, X. Z. Ding, A. B. Roginsky, R. H. Bell Jr., T. E. Adrian, On the role of transforming growth factor-β in the growth inhibitory effects of retinoic acid in human pancreatic cancer cells. Mol. Cancer 6, 82 (2007).
-
(2007)
Mol. Cancer
, vol.6
, pp. 82
-
-
Singh, B.1
Murphy, R.F.2
Ding, X.Z.3
Roginsky, A.B.4
Bell Jr., R.H.5
Adrian, T.E.6
-
36
-
-
58249089671
-
Holding their own: The noncanonical roles of Smad proteins
-
L. L. Hoover, S. W. Kubalak, Holding their own: The noncanonical roles of Smad proteins. Sci. Signal. 1, pe48 (2008).
-
(2008)
Sci. Signal
, vol.1
-
-
Hoover, L.L.1
Kubalak, S.W.2
|