Synthesis and antiproliferative evaluation of certain indeno[1,2-c] quinoline derivatives. Part 2

Journal of Medicinal Chemistry

Volumn 53, Issue 16, 2010, Pages 6164-6179

  Tseng, Chih Hua ^a   Tzeng, Cherng Chyi ^a   Yang, Chiao Li ^a   Lu, Pei Jung ^b   Chen, Hui Ling ^b   Li, Hao Yi ^c   Chuang, You Chung ^c   Yang, Chia Ning ^c   Chen, Yeh Long ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL UNIVERSITY OF KAOHSIUNG   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

6 HYDROXY 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE; 6 HYDROXY 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 (DIMETHYLAMINO)ETHYL OXIME; 6 HYDROXY 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 (PIPERIDIN 1 YL)ETHYL OXIME; 6 HYDROXY 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 (PYRROLIDIN 1 YL)ETHYL OXIME; 6 HYDROXY 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 MORPHOLINOETHYL OXIME; 6 HYDROXY 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 3 (DIMETHYLAMINO)PROPYL OXIME; 6 HYDROXY 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE OXIME; 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE; 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 (DIMETHYLAMINO)ETHYL OXIME; 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 (PIPERDIN 1 YL)ETHYL OXIME; 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 (PYRROLIDIN 1 YL)ETHYL OXIME; 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 MORPHOLINOETHYL OXIME; 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE O 3 (DIMETHYLAMINO)PROPYL OXIME; 9 METHOXY 11H INDENO[1,2 C]QUINOLIN 11 ONE OXIME; 9 METHOXY 6 (PIPERAZIN 1 YL) 11H INDENO[1,2 C]QUINOLIN 11 ONE O 2 (PYRROLIDIN 1 YL)ETHYL OXIME; ANTINEOPLASTIC AGENT; CASPASE 3; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); HISTONE H2AX; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; DNA FRAGMENTATION; DRUG BLOOD LEVEL; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; SINGLE DRUG DOSE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; DNA; DNA FRAGMENTATION; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDROXYQUINOLINES; INDENES; MALE; MICE; MICE, NUDE; MODELS, MOLECULAR; NEOPLASM TRANSPLANTATION; OXIMES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINOLINES; STEREOISOMERISM; TRANSPLANTATION, HETEROLOGOUS;

EID: 77955894751     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm1005447     Document Type: Article

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