Structure-activity relationships for the antileishmanial and antitrypanosomal activities of 1'-substituted 9-anilinoacridines

Journal of Medicinal Chemistry

Volumn 40, Issue 16, 1997, Pages 2634-2642

  Gamage, Swarna A ^a   Figgitt, David P ^b   Wojcik, Stanley J ^b   Ralph, Raymond K ^b   Ransijn, Adriana ^c   Mauel, Jacques ^c   Yardley, Vanessa ^d   Snowdon, Diane ^d   Croft, Simon L ^d   Denny, William A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

9 ANILINOACRIDINE DERIVATIVE; MEPACRINE;

ARTICLE; ELECTRON TRANSPORT; ENZYME ACTIVITY; FLAGELLATE; LEISHMANIA DONOVANI; LEISHMANIASIS; LIPOPHILICITY; MALARIA; PROMASTIGOTE; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

AMSACRINE; ANIMALS; ANTIPROTOZOAL AGENTS; HUMANS; LEISHMANIA DONOVANI; LEISHMANIA MAJOR; MACROPHAGES; MICE; MICE, INBRED CBA; MODELS, CHEMICAL; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA CRUZI; TUMOR CELLS, CULTURED;

EID: 0001161484     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970232h     Document Type: Article

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