Synthesis and antiproliferative evaluation of 6-arylindeno[1,2-c]quinoline derivatives

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 21, 2009, Pages 7465-7476

  Tseng, Chih Hua ^a   Chen, Yeh Long ^a   Chung, Kuin Yu ^a   Cheng, Chih Mei ^a   Wang, Chi Huei ^a   Tzeng, Cherng Chyi ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

6 arylindeno 1,2 c quinoline derivatives; Antiproliferative activity; DNA fragmentation apoptotic induction

Indexed keywords

2,9 BIS[3 (DIMETHYLAMINO)PROPOXY] 6 [4 [3 (DIMETHYLAMINO)PROPOXY]PHENYL] 11H INDENO[1,2 C]QUINOLIN 11 ONE; 9 [3 (DIMETHYLAMINO)PROPOXY] 6 [4 [3 (DIMETHYLAMINO)PROPOXY]PHENYL] 2 FLUORO 11H INDENO[1,2 C]QUINOLIN 11 ONE; IRINOTECAN; QUINOLINE DERIVATIVE; TOPOTECAN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; INDENE DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TUBULIN;

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG SCREENING; DRUG SYNTHESIS; HEP 2 CELL; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; CHEMISTRY; METABOLISM; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; G2 PHASE; HUMANS; INDENES; POLY(ADP-RIBOSE) POLYMERASES; QUINOLINES; TUBULIN;

EID: 73949126608     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.09.021     Document Type: Article

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