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Volumn 1587, Issue 2-3, 2002, Pages 155-163
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Self-association and unique DNA binding properties of the anti-cancer agent TAS-103, a dual inhibitor of topoisomerases I and II
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Author keywords
DNA binder; Dual inhibitor; Self association; TAS 103; Topoisomerase
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Indexed keywords
6 [2 (DIMETHYLAMINO)ETHYLAMINO] 3 HYDROXY 7H INDENO[2,1 C]QUINOLIN 7 ONE;
DNA TOPOISOMERASE;
DNA TOPOISOMERASE (ATP HYDROLYSING);
DNA TOPOISOMERASE INHIBITOR;
ETHIDIUM BROMIDE;
AQUEOUS SOLUTION;
CHROMATOPHORE;
DNA BINDING;
DRUG DNA BINDING;
DRUG POTENCY;
HYDROPHOBICITY;
MELTING POINT;
PHOSPHORUS NUCLEAR MAGNETIC RESONANCE;
PRIORITY JOURNAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
REVIEW;
STRUCTURE ACTIVITY RELATION;
TITRIMETRY;
ULTRAVIOLET SPECTROSCOPY;
AMINOQUINOLINES;
ANIMALS;
ANTINEOPLASTIC AGENTS;
BASE SEQUENCE;
BINDING SITES;
CATTLE;
DIMERIZATION;
DNA;
DNA TOPOISOMERASES, TYPE I;
DNA TOPOISOMERASES, TYPE II;
ENZYME INHIBITORS;
INDENES;
MODELS, MOLECULAR;
NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;
OLIGODEOXYRIBONUCLEOTIDES;
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EID: 0037130278
PISSN: 09254439
EISSN: None
Source Type: Journal
DOI: 10.1016/S0925-4439(02)00078-9 Document Type: Review |
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Times cited : (36)
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References (31)
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