SCOPUS 정보 검색 플랫폼

Volumn 45, Issue 1, 2002, Pages 242-249

Synthesis of new dihydroindeno[1,2-c]isoquinoline and indenoisoquinolinium chloride topoisomerase I inhibitors having high in vivo anticancer activity in the hollow fiber animal model

(6) Jayaraman, M a Fox, B M a Hollingshead, M b Kohlhagen, G c Pommier, Y c Cushman, M a

a PURDUE UNIVERSITY (United States)

b NATIONAL CANCER INSTITUTE (United States)

c NATIONAL CANCER INSTITUTE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIMETHOXY 8,9 (METHYLENEDIOXY) 6 (1 PROPYL) 11H INDENOL[1,2 C]ISOQUINOLINIUM CHLORIDE; CAMPTOTHECIN; CYTOTOXIC AGENT; DIHYDROINDENO[1,2 C]ISOQUINOLINE; DNA TOPOISOMERASE INHIBITOR; INDENOISOQUINOLINE DERIVATIVE; ISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; DNA CLEAVAGE; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; DNA TOPOISOMERASES, TYPE I; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; ISOQUINOLINES; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0037011905 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm000498f Document Type: Article

Times cited : (96)

References (16)

1
- 0033047992
- Synthesis of cytotoxic indenoisoquinoline topoisomerase I poisons
- (1999) J. Med. Chem. , vol.42 , pp. 446-457
- Strumberg, D.¹ Pommier, Y.² Paull, K.³ Jayaraman, M.⁴ Nagafuji, P.⁵ Cushman, M.⁶

2
- 33947087705
- Phosphorus entoxide-methansulfonic acid. A convenient alternative to polyphosphoric acid
- (1973) J. Org. Chem. , vol.38 , pp. 4071-4073
- Eaton, R.E.¹ Carlson, G.R.² Lee, J.T.³

3
- 0002474961
- Structures of new benzophenanthridine alkaloids from Zanthoxylum nitidum
- (1958) Chem. Ind. (London) , pp. 1514
- Arthur, H.R.¹ Hui, W.H.² Ng, Y.L.³

4
- 0002745795
- Examination of rutaceae of Hong Kong. II. Alkaloids, nitidine, and oxynitidine, from Zanthoxylum nitidum
- (1959) J. Chem. Soc. , pp. 1840-1845
- Arthur, H.R.¹ Hui, W.H.² Ng, Y.L.³

5
- 0016423038
- Preparation and antileukemic activity of some alkoxybenzo[c]phenanthridinium salts and corresponding dihydro derivatives
- (1975) J. Med. Chem. , vol.18 , pp. 66-71
- Zee-Cheng, R.¹ Cheng, K.-Y.²

6
- 0015421973
- Fagaronine, a new tumor inhibitor isolated from Fagara zanthoxyloides Lam. (Rutaceae)
- (1972) J. Pharm. Sci. , vol.61 , pp. 1858-1859
- Messmer, W.M.¹ Tin-Wa, M.² Pong, H.H.S.³ Bevelle, C.⁴ Farnsworth, N.R.⁵ Abraham, D.J.⁶ Trojanek, J.⁷

7
- 0016799530
- Synthesis and biological activity of some antitumor benzophenanthridinium salts
- (1975) J. Med. Chem. , vol.18 , pp. 708-713
- Stermitz, P.R.¹ Gillespie, J.P.² Amoros, L.G.³ Romero, R.⁴ Stermitz, T.A.⁵ Larson, K.A.⁶ Earl, S.⁷ Ogg, J.E.⁸

8
- 0021260108
- Synthesis and biological activity of structural analogues of the anticancer benzophenanthridine alkaloid nitidine chloride
- (1984) J. Med. Chem. , vol.27 , pp. 544-547
- Cushman, M.¹ Mohan, P.² Smith, E.C.R.³

9
- 0032539981
- Mammalian DNA topoisomerase I activity and poisoning by camptothecin are inhibited by simian virus 40 large T antigen
- (1998) Biochemistry , vol.37 , pp. 3818-3823
- Pommier, Y.¹ Kohlhagen, G.² Wu, C.³ Simmons, D.T.⁴

10
- 0034609859
- Synthesis of new indeno[1,2-c]isoquinolines: Cytotoxic non-camptothecin topoisomerase I inhibitors
- (2000) J. Med. Chem. , vol.43 , pp. 3688-3698
- Cushman, M.¹ Jayaraman, M.² Vroman, J.A.³ Fukunaga, A.K.⁴ Fox, B.M.⁵ Kohlhagen, G.⁶ Strumberg, D.⁷ Pommier, Y.⁸

11
- 0001852317
- Teicher, B., Ed.; Humana Press: Totowa, NJ
- (1997) Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval , pp. 101-125
- Plowman, J.¹ Dykes, D.J.² Hollingshead, M.³ Simpson-Herren, L.⁴ Alley, M.C.⁵

12
- 0000393418
- The hollow fiber assay
- (1999) Contrib. Oncol. , vol.54 , pp. 109-120
- Hollingshead, M.¹ Plowman, J.² Alley, M.³ Mayo, J.⁴ Sausville, E.⁵

13
- 0028225471
- Comparison of topoisomerase I inhibition, DNA damage, and cytotoxocity of camptothecin derivatives presently in clinical trials
- (1994) J. Natl. Cancer Inst. , vol.86 , pp. 836-842
- Tanizawa, A.¹ Fujimori, A.² Fujimori, Y.³ Pommier, Y.⁴

14
- 0001604814
- Novel oxidative transformation of indenoisoquinolines to isoquinoline-3-spiro-3-phthalides in the presence of osmium tetroxide and 4-methylmorpholine N-oxide
- (1998) J. Org. Chem. , vol.63 , pp. 5736-5737
- Jayaraman, M.¹ Fanwick, P.E.² Cushman, M.³

15
- 0033605675
- Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7,8-dihydro-8-oxoguanine and 5-hydroxycytosine
- (1999) J. Biol. Chem. , vol.274 , pp. 8516-8523
- Pourquierm, P.¹ Ueng, L.-M.² Fertala, J.³ Wang, D.⁴ Park, H.-J.⁵ Essigmann, J.M.⁶ Bjornsti, M.-A.⁷ Pommier, Y.⁸

16
- 0031815336
- Protein-linked DNA strand breaks induced by NSC 314622, a novel noncamptothecin topoisomerase I poison
- (1998) Mol. Pharmacol. , vol.54 , pp. 50-58
- Kohlhagen, G.¹ Paull, K.² Cushman, M.³ Nagafuji, P.⁴ Pommier, Y.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.