메뉴 건너뛰기




Volumn 17, Issue 25, 2010, Pages 2729-2745

Organometallic complexes: New tools for chemotherapy

Author keywords

Bioorganometallic chemistry; Chemotherapy; Metallocenes; Organometallic complexes

Indexed keywords

ANSA TITANOCENE DERIVATIVE; ANTINEOPLASTIC AGENT; ARSPHENAMINE; ARTEMISININ; BENZENE; CHLOROQUINE; CISPLATIN; FERROCENE; FERROCENE DERIVATIVE; FERROCIFEN DERIVATIVE; FERROCIPHEN DERIVATIVE; FERROCIPHENOL DERIVATIVE; INDAZOLIUM TETRACHLOROBIS(INDAZOLE)RUTHENATE; MEFLOQUINE; MEPACRINE; NILUTAMIDE; OXALI TITANOCENE Y; QUININE; RUTHENOCENE DERIVATIVE; TAMOXIFEN; THIOSEMICARBAZONE; TITANOCENE; TITANOCENE C; TITANOCENE DICHLORIDE; TITANOCENE Y; UNCLASSIFIED DRUG;

EID: 77955613063     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986710791859306     Document Type: Article
Times cited : (94)

References (171)
  • 1
    • 11144333768 scopus 로고    scopus 로고
    • Bioorganometallic chemistry of ferrocene
    • Van Staveren, D. R.; Metzler-Nolte, N. Bioorganometallic chemistry of ferrocene. Chem. Rev., 2004, 104, 5931-5985.
    • (2004) Chem. Rev , vol.104 , pp. 5931-5985
    • van Staveren, D.R.1    Metzler-Nolte, N.2
  • 2
    • 62449161586 scopus 로고    scopus 로고
    • Bioorganometallic chemistry-from teaching paradigms to medicinal applications
    • Hartinger, C. G.; Dyson, P. J. Bioorganometallic chemistry-from teaching paradigms to medicinal applications. Chem. Soc. Rev., 2009, 38, 391-401.
    • (2009) Chem. Soc. Rev , vol.38 , pp. 391-401
    • Hartinger, C.G.1    Dyson, P.J.2
  • 3
    • 0036937951 scopus 로고    scopus 로고
    • Ein faszinierendes Forschungsgebiet Biometallorganische Chemie
    • Beck, W.; Severin, K. Ein faszinierendes Forschungsgebiet Biometallorganische Chemie. Chem. Unserer Zeit, 2002, 36, 356-365.
    • (2002) Chem. Unserer Zeit , vol.36 , pp. 356-365
    • Beck, W.1    Severin, K.2
  • 4
    • 0001503857 scopus 로고
    • Chromium tricarbonyl complexes of estradiol derivatives; differentiation of α and β diastereomers using 1 and 2 dimensional NMR spectroscopy at 500 MHz
    • Top, S.; Jaouen, G.; VessiLres, A.; Abjean, J. P.; Davoust, D. Rodger, C. A.; Sayer, B. G.; McGlinchey, M. J. Chromium tricarbonyl complexes of estradiol derivatives; differentiation of α and β diastereomers using 1 and 2 dimensional NMR spectroscopy at 500 MHz. Organometallics, 1985, 4, 2143-2150.
    • (1985) Organometallics , vol.4 , pp. 2143-2150
    • Top, S.1    Jaouen, G.2    Vessilres, A.3    Abjean, J.P.4    Davoust, D.5    Rodger, C.A.6    Sayer, B.G.7    McGlinchey, M.J.8
  • 5
    • 61849162674 scopus 로고    scopus 로고
    • Targeting proteins with metal complexes
    • Meggers, E. Targeting proteins with metal complexes. Chem. Commun., 2009, 1001-1010.
    • (2009) Chem. Commun , pp. 1001-1010
    • Meggers, E.1
  • 6
    • 34250728162 scopus 로고    scopus 로고
    • Exploring biologically relevant chemical space with metal complexes
    • Meggers, E. Exploring biologically relevant chemical space with metal complexes. Curr. Opin. Chem. Biol., 2007, 11, 287.
    • (2007) Curr. Opin. Chem. Biol , vol.11 , pp. 287
    • Meggers, E.1
  • 9
    • 33748599842 scopus 로고    scopus 로고
    • Organometallic compounds with biological activity: A very selective and highly potent cellular inhibitor for glycogen synthase kinase 3
    • Atilla-Gokcumen, G. E.; Williams, D. S.; Bregman, H.; Pagano, N.; Meggers, E. Organometallic compounds with biological activity: a very selective and highly potent cellular inhibitor for glycogen synthase kinase 3. Chem Bio Chem, 2006, 7, 1443-1450.
    • (2006) Chem Bio Chem , vol.7 , pp. 1443-1450
    • Atilla-Gokcumen, G.E.1    Williams, D.S.2    Bregman, H.3    Pagano, N.4    Meggers, E.5
  • 10
    • 0024549357 scopus 로고
    • Tumor inhibition by ferricenium complexes. Activity against some solid experimental tumors
    • Köpf-Maier, P.; Klapötke, T. Tumor inhibition by ferricenium complexes. Activity against some solid experimental tumors. Arzneimittelforschung, 1989, 39, 369-371.
    • (1989) Arzneimittelforschung , vol.39 , pp. 369-371
    • Köpf-Maier, P.1    Klapötke, T.2
  • 11
    • 0024358741 scopus 로고
    • High efficiency of ferricenium salts as radiosensitizers of V79 cells in vitro and the KHT tumor in vivo
    • Joy, A. M.; Goodgame, D. M.; Stratford, I. J. High efficiency of ferricenium salts as radiosensitizers of V79 cells in vitro and the KHT tumor in vivo. Int. J. Radiat. Oncol. Biol. Phys., 1989, 16, 1053-1056.
    • (1989) Int. J. Radiat. Oncol. Biol. Phys , vol.16 , pp. 1053-1056
    • Joy, A.M.1    Goodgame, D.M.2    Stratford, I.J.3
  • 12
    • 0030597973 scopus 로고    scopus 로고
    • N-(2-ferroceneethyl) maleimide: A new electroactive sulphydryl-specific reagent for cysteine-containing peptides and proteins
    • Di Gleria, K.; Hill, H. A.; Wong, L. L. N-(2-ferroceneethyl) maleimide: a new electroactive sulphydryl-specific reagent for cysteine-containing peptides and proteins. FEBS Lett., 1996, 390, 142-144.
    • (1996) FEBS Lett , vol.390 , pp. 142-144
    • Di Gleria, K.1    Hill, H.A.2    Wong, L.L.3
  • 13
    • 0031706070 scopus 로고    scopus 로고
    • Octanol-water partition: Searching for predictive models
    • Buchwald, P.; Bodor, N. Octanol-water partition: searching for predictive models. Curr. Med. Chem., 1998, 5, 353-380.
    • (1998) Curr. Med. Chem , vol.5 , pp. 353-380
    • Buchwald, P.1    Bodor, N.2
  • 14
    • 0033770937 scopus 로고    scopus 로고
    • Solvation descriptors for ferrocene, and the estimation of some physicochemical and biochemical properties
    • Abraham, M. H.; Benjelloun-Dakhama, Gola, J. M. R.; Acree, Jr., W. E., Cain, W. S.; Cometto-Muniz, J. E. Solvation descriptors for ferrocene, and the estimation of some physicochemical and biochemical properties. New J. Chem., 2000, 24, 825-829.
    • (2000) New J. Chem , vol.24 , pp. 825-829
    • Abraham, M.H.1    Benjelloun-Dakhama2    Gola, J.M.R.3    Acree Jr., W.E.4    Cain, W.S.5    Cometto-Muniz, J.E.6
  • 15
    • 37049053957 scopus 로고
    • Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode
    • Rosenberg, B.; Van Camp, L.; Krigas, T. Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode. Nature, 1965, 205, 698-699.
    • (1965) Nature , vol.205 , pp. 698-699
    • Rosenberg, B.1    van Camp, L.2    Krigas, T.3
  • 16
    • 0014691619 scopus 로고
    • Platinum compounds: A new class of potent antitumour agents
    • Rosenberg, B.; VanCamp, L.; Trosko, J. E.; Mansour, V. H. Platinum compounds: a new class of potent antitumour agents. Nature, 1969, 222, 385-386.
    • (1969) Nature , vol.222 , pp. 385-386
    • Rosenberg, B.1    Vancamp, L.2    Trosko, J.E.3    Mansour, V.H.4
  • 17
    • 0344938002 scopus 로고    scopus 로고
    • Antitumor activity of titanocene dichloride in xenografted human renal-cell carcinoma
    • Köpf-Maier, P. Antitumor activity of titanocene dichloride in xenografted human renal-cell carcinoma. Anticancer Res., 1999, 19, 493-504.
    • (1999) Anticancer Res , vol.19 , pp. 493-504
    • Köpf-Maier, P.1
  • 18
    • 0036272526 scopus 로고    scopus 로고
    • Titanium complexes in cancer treatment
    • Meléndez, E. Titanium complexes in cancer treatment. Crit. Rev. Oncol. Hematol., 2002, 42, 309-315.
    • (2002) Crit. Rev. Oncol. Hematol , vol.42 , pp. 309-315
    • Meléndez, E.1
  • 20
    • 0034773816 scopus 로고    scopus 로고
    • Titanium(IV) targets phosphoesters on nucleotides: Implications for the mechanism of action of the anticancer drug titanocene dichloride
    • Guo, M.; Guo, Z.; Sadler, P.J. Titanium(IV) targets phosphoesters on nucleotides: implications for the mechanism of action of the anticancer drug titanocene dichloride. J. Biol. Inorg. Chem., 2001, 6, 698-707.
    • (2001) J. Biol. Inorg. Chem , vol.6 , pp. 698-707
    • Guo, M.1    Guo, Z.2    Sadler, P.J.3
  • 21
    • 0034702778 scopus 로고    scopus 로고
    • Ti(IV) uptake and release by human serum transferrin and recognition of Ti(IV)-transferrin by cancer cells: Understanding the mechanism of action of the anticancer drug titanocene dichloride
    • Guo, M.; Sun, H.; McArdle, H.J.; Gambling, L.; Sadler, P.J. Ti(IV) uptake and release by human serum transferrin and recognition of Ti(IV)-transferrin by cancer cells: understanding the mechanism of action of the anticancer drug titanocene dichloride. Biochemistry, 2000, 39, 10023-10033.
    • (2000) Biochemistry , vol.39 , pp. 10023-10033
    • Guo, M.1    Sun, H.2    McArdle, H.J.3    Gambling, L.4    Sadler, P.J.5
  • 22
    • 0032985063 scopus 로고    scopus 로고
    • Transferrin As A targeting ligand for liposomes and anticancer drugs
    • Singh, M. Transferrin As A targeting ligand for liposomes and anticancer drugs. Curr. Pharm. Des., 1999, 5, 443-451.
    • (1999) Curr. Pharm. Des , vol.5 , pp. 443-451
    • Singh, M.1
  • 23
    • 0034517194 scopus 로고    scopus 로고
    • Phase I clinical trial of a day-1, -3, -5 every 3 weeksphase i clinical trial of day-1, -3, -5 every 3 weeks schedule with titanocene dichloride (MKT 5) in Patients with advanced cancer. (Phase I Study Group of the AIO of the German Cancer Society)
    • Mross, K.; Robben-Bathe, P.; Edler, L.; Baumgart, J.; Berdel, W. E.; Fiebig, H.; Unger C. Phase I clinical trial of a day-1, -3, -5 every 3 weeksphase i clinical trial of day-1, -3, -5 every 3 weeks schedule with titanocene dichloride (MKT 5) in Patients with advanced cancer. (Phase I Study Group of the AIO of the German Cancer Society). Onkologie, 2000, 23, 576-579.
    • (2000) Onkologie , vol.23 , pp. 576-579
    • Mross, K.1    Robben-Bathe, P.2    Edler, L.3    Baumgart, J.4    Berdel, W.E.5    Fiebig, H.6    Unger, C.7
  • 24
    • 0001237421 scopus 로고    scopus 로고
    • Novel synthesis of ansa-metallocenes via the reductive dimerization of fulvenes with group 4 metal divalent halides
    • Eisch, J.; Shi, X.; Owuor, F. Novel synthesis of ansa-metallocenes via the reductive dimerization of fulvenes with group 4 metal divalent halides. Organometallics, 1998, 17, 5219-5221.
    • (1998) Organometallics , vol.17 , pp. 5219-5221
    • Eisch, J.1    Shi, X.2    Owuor, F.3
  • 25
    • 0346155937 scopus 로고    scopus 로고
    • Novel derivatives of ansa-titanocenes procured from 6-phenylfulvene: A combined experimental and theoretical study
    • Fox, S.; Dunne, J.P.; Tacke, M.; Gallagher J. F. Novel derivatives of ansa-titanocenes procured from 6-phenylfulvene: a combined experimental and theoretical study. Inorg. Chimica Acta, 2004, 357, 225-234.
    • (2004) Inorg. Chimica Acta , vol.357 , pp. 225-234
    • Fox, S.1    Dunne, J.P.2    Tacke, M.3    Gallagher, J.F.4
  • 28
    • 8444227535 scopus 로고    scopus 로고
    • Methoxy-phenyl substituted ansa-titanocenes as potential anti-cancer drugs derived from fulvenes and titanium dichloride
    • Tacke, M.; Cuffe, L. P.; Gallagher, W.M.; Lou, Y.; Mendoza, O. Müller-Bunz, H.; Rehmann, F.J.; Sweeney, N. Methoxy-phenyl substituted ansa-titanocenes as potential anti-cancer drugs derived from fulvenes and titanium dichloride. J. Inorg. Biochem., 2004, 98, 1987-1994.
    • (2004) J. Inorg. Biochem , vol.98 , pp. 1987-1994
    • Tacke, M.1    Cuffe, L.P.2    Gallagher, W.M.3    Lou, Y.4    Mendoza, O.5    Müller-Bunz, H.6    Rehmann, F.J.7    Sweeney, N.8
  • 31
    • 33744822735 scopus 로고    scopus 로고
    • Diarylmethyl substituted titanocenes: Promising anti-cancer drugs
    • Pampillon, C.; Mendoza, O.; Sweeney, N. J.; Strohfeldt, K.; Tacke, M. Diarylmethyl substituted titanocenes: Promising anti-cancer drugs. Polyhedron, 2006, 25, 2101-2108.
    • (2006) Polyhedron , vol.25 , pp. 2101-2108
    • Pampillon, C.1    Mendoza, O.2    Sweeney, N.J.3    Strohfeldt, K.4    Tacke, M.5
  • 32
    • 33746209336 scopus 로고    scopus 로고
    • Diheteroarylmethyl substituted titanocenes: A novel class of potential anti-cancer drugs
    • Pampillon, C.; Sweeney, N.; Strohfeldt, K.; Tacke, M. Diheteroarylmethyl substituted titanocenes: a novel class of potential anti-cancer drugs. Inorg. Chimica Acta, 2006, 359, 3969-3975.
    • (2006) Inorg. Chimica Acta , vol.359 , pp. 3969-3975
    • Pampillon, C.1    Sweeney, N.2    Strohfeldt, K.3    Tacke, M.4
  • 36
    • 0942266508 scopus 로고    scopus 로고
    • Functionalized cyclopentadienyl titanium organometallic compounds as new antitumor drugs
    • Allen, O.; Croll, L.; Gott, A. L.; Knox, R. J.; McGowan, P. C. Functionalized cyclopentadienyl titanium organometallic compounds as new antitumor drugs. Organometallics, 2004, 23, 288-292.
    • (2004) Organometallics , vol.23 , pp. 288-292
    • Allen, O.1    Croll, L.2    Gott, A.L.3    Knox, R.J.4    McGowan, P.C.5
  • 37
    • 4544314578 scopus 로고    scopus 로고
    • Synthesis, characterization, and assessment of cytotoxic properties of a series of titanocene dichloride derivatives
    • Causey, P. W.; Baird, M. C.; Cole, S. P. C. Synthesis, characterization, and assessment of cytotoxic properties of a series of titanocene dichloride derivatives. Organometallics, 2004, 23, 4486-4494.
    • (2004) Organometallics , vol.23 , pp. 4486-4494
    • Causey, P.W.1    Baird, M.C.2    Cole, S.P.C.3
  • 38
    • 11144322397 scopus 로고    scopus 로고
    • Synthesis, characterization and antitumor properties of titanocene derivatives with thiophene containing ligands
    • Meyer, R., Brinka, S.; van Rensburgb, C. E. J.; Joonéb, G. K. Görlsc, H.; Lotz, S. Synthesis, characterization and antitumor properties of titanocene derivatives with thiophene containing ligands. J. Organomet. Chem., 2005, 690, 117-125.
    • (2005) J. Organomet. Chem , vol.690 , pp. 117-125
    • Meyer, R.1    Brinka, S.2    van Rensburgb, C.E.J.3    Joonéb, G.K.4    Görlsc, H.5    Lotz, S.6
  • 39
    • 44349158338 scopus 로고    scopus 로고
    • Bioorganometallic fulvene-derived titanocene anti-cancer drugs
    • Strohfeldt K.; Tacke, M. Bioorganometallic fulvene-derived titanocene anti-cancer drugs. Chem. Soc. Rev., 2008, 37, 1174-1187.
    • (2008) Chem. Soc. Rev , vol.37 , pp. 1174-1187
    • Strohfeldt, K.1    Tacke, M.2
  • 40
    • 27644514186 scopus 로고    scopus 로고
    • In-vitro anti-tumor activity studies of bridged and unbridged benzyl- substituted titanocenes
    • Kelter, G.; Sweeney, N. J.; Strohfeldt, K.; Fiebig, H. H.; Tacke, M. In-vitro anti-tumor activity studies of bridged and unbridged benzyl- substituted titanocenes. Anti-Cancer Drugs, 2005, 16, 1091-1098.
    • (2005) Anti-Cancer Drugs , vol.16 , pp. 1091-1098
    • Kelter, G.1    Sweeney, N.J.2    Strohfeldt, K.3    Fiebig, H.H.4    Tacke, M.5
  • 41
    • 27644536324 scopus 로고    scopus 로고
    • Activity of [1,2-di(cyclopentadienyl)-1,2-di(p-N,N-dimethylaminophenyl)-ethanediyl] titanium dichloride against tumor colony-forming units
    • Oberschmidt, O.; Hanauske, A.R.; Rehmann, F.J.; Strohfeldt, K. Sweeney, N.; Tacke M. Activity of [1,2-di(cyclopentadienyl)-1,2-di(p-N,N-dimethylaminophenyl)-ethanediyl] titanium dichloride against tumor colony-forming units. Anti-Cancer Drugs, 2005, 16, 1071-1073.
    • (2005) Anti-Cancer Drugs , vol.16 , pp. 1071-1073
    • Oberschmidt, O.1    Hanauske, A.R.2    Rehmann, F.J.3    Strohfeldt, K.4    Sweeney, N.5    Tacke, M.6
  • 42
    • 33745806258 scopus 로고    scopus 로고
    • Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells
    • O'Connor K. G. C.; Tacke, M.; Rehmann, F. J.; Strohfeldt, K. Sweeney, N.; Fitzpatrick, J. M.; Watson, R. W. Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells. Apoptosis, 2006, 11, 1205-1214.
    • (2006) Apoptosis , vol.11 , pp. 1205-1214
    • O'Connor, K.G.C.1    Tacke, M.2    Rehmann, F.J.3    Strohfeldt, K.4    Sweeney, N.5    Fitzpatrick, J.M.6    Watson, R.W.7
  • 43
    • 34047182504 scopus 로고    scopus 로고
    • Synthesis and cytotoxicity studies of new dimethylamino-functionalized and heteroaryl-substituted titanocene anti-cancer drugs
    • Pampillion, C.; Sweeney, N.; Strohfeldt, K.; Ttacke, M. Synthesis and cytotoxicity studies of new dimethylamino-functionalized and heteroaryl-substituted titanocene anti-cancer drugs. Orgomet. Chem., 2007, 692, 2153-2159.
    • (2007) Orgomet. Chem , vol.692 , pp. 2153-2159
    • Pampillion, C.1    Sweeney, N.2    Strohfeldt, K.3    Ttacke, M.4
  • 45
    • 42949166140 scopus 로고    scopus 로고
    • Synthesis and cytotoxicity studies of new morpholino-functionalised and Nheteroaryl- substituted titanocene anticancer drugs
    • Hogan, M.; Claffey, J.; Pampillón, C.; Tacke, M. Synthesis and cytotoxicity studies of new morpholino-functionalised and Nheteroaryl- substituted titanocene anticancer drugs. Med. Chem., 2008, 4, 91-99.
    • (2008) Med. Chem , vol.4 , pp. 91-99
    • Hogan, M.1    Claffey, J.2    Pampillón, C.3    Tacke, M.4
  • 46
    • 41049087054 scopus 로고    scopus 로고
    • Novel achiral titanocene anti-cancer drugs synthesised from bis-N, Ndimethylamino fulvene and lithiated heterocyclic compounds
    • Pampillón, C.; Claffey, J.; Hogan, M.; Tacke, M. Novel achiral titanocene anti-cancer drugs synthesised from bis-N,Ndimethylamino fulvene and lithiated heterocyclic compounds. Biometals, 2008, 21, 197-204.
    • (2008) Biometals , vol.21 , pp. 197-204
    • Pampillón, C.1    Claffey, J.2    Hogan, M.3    Tacke, M.4
  • 47
    • 11044238970 scopus 로고    scopus 로고
    • Bis(enamino-Cp) Group 4 metal complex chemistry: Developing a Mannich-type carbon-carbon coupling reaction at the bent metallocene famework
    • Knüppel, S.; Wang, C.; Kehr, G.; Fröhlich, R.; Erker, G. Bis(enamino-Cp) Group 4 metal complex chemistry: developing a Mannich-type carbon-carbon coupling reaction at the bent metallocene famework. J. Organomet. Chem., 2005, 690, 14-32.
    • (2005) J. Organomet. Chem , vol.690 , pp. 14-32
    • Knüppel, S.1    Wang, C.2    Kehr, G.3    Fröhlich, R.4    Erker, G.5
  • 48
    • 34547665643 scopus 로고    scopus 로고
    • Dimethylamino-functionalised and N-heteroarylsubstituted titanocene anticancer drugs: Synthesis and cytotoxicity studies
    • Hickey, T.; Claffey, J.; Fitzpatrick, E.; Hogan, M.; Pampillón, C. Tacke, M. Dimethylamino-functionalised and N-heteroarylsubstituted titanocene anticancer drugs: synthesis and cytotoxicity studies. Invest. New Drugs, 2007, 25, 425-433.
    • (2007) Invest. New Drugs , vol.25 , pp. 425-433
    • Hickey, T.1    Claffey, J.2    Fitzpatrick, E.3    Hogan, M.4    Pampillón, C.5    Tacke, M.6
  • 49
    • 0037714214 scopus 로고    scopus 로고
    • Tumour-inhibiting platinum complexes-state of the art and future perspectives
    • Jakupec, M. A.; Galanski, M.; Keppler, B. K. Tumour-inhibiting platinum complexes-state of the art and future perspectives. Rev. Physiol. Biochem. Pharmacol., 2003, 146, 1-54.
    • (2003) Rev. Physiol. Biochem. Pharmacol , vol.146 , pp. 1-54
    • Jakupec, M.A.1    Galanski, M.2    Keppler, B.K.3
  • 52
    • 0031322560 scopus 로고    scopus 로고
    • DNA cleaving activity and cytotoxic activity of ferricenium cations
    • Tamura, H.; Miwa, M. DNA cleaving activity and cytotoxic activity of ferricenium cations. Chem. Lett., 1997, 26, 1177-1178
    • (1997) Chem. Lett , vol.26 , pp. 1177-1178
    • Tamura, H.1    Miwa, M.2
  • 54
    • 0037137615 scopus 로고    scopus 로고
    • Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process
    • Tabbi, G.; Cassino, C.; Cavigiolio, G.; Colangelo, D.; Ghiglia, A. Viano, I.; Osella, D. Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process. J. Med. Chem., 2002, 45, 5786-5796.
    • (2002) J. Med. Chem , vol.45 , pp. 5786-5796
    • Tabbi, G.1    Cassino, C.2    Cavigiolio, G.3    Colangelo, D.4    Ghiglia, A.5    Viano, I.6    Osella, D.7
  • 55
    • 0018086203 scopus 로고
    • Ferrocenyl polyamines as agents for the chemoimmunotherapy of cancer
    • Fiorina, V. J.; Dubois, R. J.; Brynes, S. Ferrocenyl polyamines as agents for the chemoimmunotherapy of cancer. J. Med. Chem., 1978, 21, 393-395.
    • (1978) J. Med. Chem , vol.21 , pp. 393-395
    • Fiorina, V.J.1    Dubois, R.J.2    Brynes, S.3
  • 57
    • 84914270648 scopus 로고
    • Synthesis, biochemistry and cytostatic effects of N-methyl-N-β-chloroethyl-hydrazones of metallocene aldehydes
    • Wenzel, M.; Schneider, M.; Liss, E. Synthesis, biochemistry and cytostatic effects of N-methyl-N-β-chloroethyl-hydrazones of metallocene aldehydes. Z. Naturforsch [C], 1979, 34, 670-676.
    • (1979) Z. Naturforsch [C] , vol.34 , pp. 670-676
    • Wenzel, M.1    Schneider, M.2    Liss, E.3
  • 58
    • 0021132242 scopus 로고
    • Ferrocenium Salts - The First Antineoplastic iron compounds
    • Köpf-Maier, P.; Köpf, H.; Neuse, E. W. Ferrocenium Salts - The First Antineoplastic iron compounds. Angew. Chem. Int. Ed. Engl., 1984, 23, 456-457.
    • (1984) Angew. Chem. Int. Ed. Engl , vol.23 , pp. 456-457
    • Köpf-Maier, P.1    Köpf, H.2    Neuse, E.W.3
  • 59
    • 0021740962 scopus 로고
    • Ferricenium complexes - a new type of water-soluble antitumor agents
    • Köpf-Meier, P.; Köpf, H.; Neuse, E. W. Ferricenium complexes - a new type of water-soluble antitumor agents. J. Cancer Res. Clin. Oncol., 1984, 108, 336-340.
    • (1984) J. Cancer Res. Clin. Oncol , vol.108 , pp. 336-340
    • Köpf-Meier, P.1    Köpf, H.2    Neuse, E.W.3
  • 60
    • 84990501699 scopus 로고
    • Evaluation of the activity of some water-soluble ferrocene and ferricenium compounds against carcinoma of the lung by the human tumor clonogenic assay
    • Neuse, E. W.; Kanzawa, F. Evaluation of the activity of some water-soluble ferrocene and ferricenium compounds against carcinoma of the lung by the human tumor clonogenic assay. Appl. Organomet. Chem., 1990, 4, 19-26.
    • (1990) Appl. Organomet. Chem , vol.4 , pp. 19-26
    • Neuse, E.W.1    Kanzawa, F.2
  • 61
    • 0000951194 scopus 로고
    • Synthesis and characterization of water-soluble polyaspartamide-ferrocene conjugates for biomedical applications
    • Swarts, J. C.; Neuse, E. W.; Lamprecht, G. J. Synthesis and characterization of water-soluble polyaspartamide-ferrocene conjugates for biomedical applications. J. Inorg. Organomet. Polymers, 1994, 4, 143-153.
    • (1994) J. Inorg. Organomet. Polymers , vol.4 , pp. 143-153
    • Swarts, J.C.1    Neuse, E.W.2    Lamprecht, G.J.3
  • 62
    • 0034909558 scopus 로고    scopus 로고
    • Polyaspartamides as water-soluble drug carriers. Part 1: Antineoplastic activity of ferrocenecontaining polyaspartamide conjugates
    • Swarts, J. C.; Swarts, D. M.; Maree, D. M.; Neuse, E. W.; La Madeleine, C.; Van Lier, J. E. Polyaspartamides as water-soluble drug carriers. Part 1: Antineoplastic activity of ferrocenecontaining polyaspartamide conjugates. Anticancer Res., 2001, 21, 2033-2037.
    • (2001) Anticancer Res , vol.21 , pp. 2033-2037
    • Swarts, J.C.1    Swarts, D.M.2    Maree, D.M.3    Neuse, E.W.4    la Madeleine, C.5    van Lier, J.E.6
  • 63
    • 0345447543 scopus 로고    scopus 로고
    • The cytotoxic activity of macromolecular ferrocene conjugates against the colo 320 DM human colon cancer line
    • Johnson, M. T.; Kreft, E.; N'Da, D. D.; Neuse, E. W.; van Rensburg, C. E. J. The cytotoxic activity of macromolecular ferrocene conjugates against the colo 320 DM human colon cancer line. J. Inorg. Organomet. Polymers, 2003, 13, 255-267.
    • (2003) J. Inorg. Organomet. Polymers , vol.13 , pp. 255-267
    • Johnson, M.T.1    Kreft, E.2    N'Da, D.D.3    Neuse, E.W.4    van Rensburg, C.E.J.5
  • 65
    • 0026460315 scopus 로고
    • A ferroceneintercalator conjugate with a potent cytotoxicity
    • Ong, C. W.; Jeng, J. Y.; Juang, S. S.; Chen, C. F. A ferroceneintercalator conjugate with a potent cytotoxicity. Bioorg. Med. Chem. Lett., 1992, 2, 929-932.
    • (1992) Bioorg. Med. Chem. Lett , vol.2 , pp. 929-932
    • Ong, C.W.1    Jeng, J.Y.2    Juang, S.S.3    Chen, C.F.4
  • 66
    • 0002395406 scopus 로고
    • Heteropolymetallic complexes of 1,1'-bis(diphenylphosphino) ferrocene (dppf). IV. Solvolytic behavior and cytostatic properties towards the KB cell-line of dppf and 1,2-bis(diphenylphosphino) ethane cis-complexes of Pt(II) and Pd(II)
    • Scarcia, V.; Furlani, A.; Longato, B.; Corain, B.; Pilloni, G. Heteropolymetallic complexes of 1,1'-bis(diphenylphosphino) ferrocene (dppf). IV. Solvolytic behavior and cytostatic properties towards the KB cell-line of dppf and 1,2-bis(diphenylphosphino) ethane cis-complexes of Pt(II) and Pd(II). Inorg. Chim. Acta, 1988, 153, 67-70.
    • (1988) Inorg. Chim. Acta , vol.153 , pp. 67-70
    • Scarcia, V.1    Furlani, A.2    Longato, B.3    Corain, B.4    Pilloni, G.5
  • 67
    • 0040003619 scopus 로고
    • S. [.mu.-1, 1'- Bis(diphenylphosphino)ferrocene]bis(chlorogold): Synthesis, iron-57 and gold-197 Moessbauer spectroscopy, x-ray crystal structure, and antitumor activity
    • Hill, D. T.; Girard, G. R.; McCabe, F. L.; Johnson, R. K.; Stupik, P. D.; Zhang, J. H.; Reiff, W. M.; Eggleston, D. S. [.mu.-1,1'- Bis(diphenylphosphino)ferrocene]bis(chlorogold): synthesis, iron-57 and gold-197 Moessbauer spectroscopy, x-ray crystal structure, and antitumor activity. Inorg. Chem., 1988, 28, 3529-3533.
    • (1988) Inorg. Chem , vol.28 , pp. 3529-3533
    • Hill, D.T.1    Girard, G.R.2    McCabe, F.L.3    Johnson, R.K.4    Stupik, P.D.5    Zhang, J.H.6    Reiff, W.M.7    Eggleston, D.8
  • 69
    • 15244345391 scopus 로고    scopus 로고
    • Chiral cyclopalladated complexes derived from N, N-dimethyl-1-phenethylamine with bridging bis(diphenylphosphine)ferrocene ligand as inhibitors of the cathepsin B activity and as antitumoral agents
    • Bincoletto, C.; Terariol, I. L. S.; Oliveira, C. R.; Dreher, S.; Fausto, D. M.; Soufen, M. A.; Nascimento, F. D.; Caires, A. C. F. Chiral cyclopalladated complexes derived from N,N-dimethyl-1-phenethylamine with bridging bis(diphenylphosphine)ferrocene ligand as inhibitors of the cathepsin B activity and as antitumoral agents. Bioorg. Med. Chem., 2005, 13, 3047-3055.
    • (2005) Bioorg. Med. Chem , vol.13 , pp. 3047-3055
    • Bincoletto, C.1    Terariol, I.L.S.2    Oliveira, C.R.3    Dreher, S.4    Fausto, D.M.5    Soufen, M.A.6    Nascimento, F.D.7    Caires, A.C.F.8
  • 70
    • 0034517753 scopus 로고    scopus 로고
    • Ferrocenes (F168, F169) and Fero-Sorbitol-Citrate (FSC): Potential anticancer drugs
    • Ferle-Vidovic, A.; Poljak-Blazi, M.; Rapic, V.; Skare, D. Ferrocenes (F168, F169) and Fero-Sorbitol-Citrate (FSC): Potential anticancer drugs. Cancer Biother. Radiopharm., 2000, 15, 617-624.
    • (2000) Cancer Biother. Radiopharm , vol.15 , pp. 617-624
    • Ferle-Vidovic, A.1    Poljak-Blazi, M.2    Rapic, V.3    Skare, D.4
  • 73
    • 60749094731 scopus 로고    scopus 로고
    • The synthesis, structural characterization and in vitro anticancer activity of novel N-(3-ferrocenyl-2-naphthoyl) dipeptide ethyl esters and novel N-(6-ferrocenyl-2-naphthoyl) dipeptide ethyl esters
    • Mooney, Á.; Corry, A. J.; O'Sullivan, D.; Rai, D. K.; Kenny, P. T. M. The synthesis, structural characterization and in vitro anticancer activity of novel N-(3-ferrocenyl-2-naphthoyl) dipeptide ethyl esters and novel N-(6-ferrocenyl-2-naphthoyl) dipeptide ethyl esters. J. Organomet. Chem., 2009, 694, 886-894.
    • (2009) J. Organomet. Chem , vol.694 , pp. 886-894
    • Mooney, A.1    Corry, A.J.2    O'Sullivan, D.3    Rai, D.K.4    Kenny, P.T.M.5
  • 75
  • 76
    • 35348952064 scopus 로고    scopus 로고
    • Antineoplastic activity of a series of ferrocene-containing alcohols
    • Shago, R. F.; Swarts, J. C.; Kreft, E.; Van Rensburg, C. E. J. Antineoplastic activity of a series of ferrocene-containing alcohols. Anticancer Res., 2007, 27, 3431-3434.
    • (2007) Anticancer Res , vol.27 , pp. 3431-3434
    • Shago, R.F.1    Swarts, J.C.2    Kreft, E.3    van Rensburg, C.E.J.4
  • 77
    • 51849143181 scopus 로고    scopus 로고
    • Synthesis of ferrocenyl oxindole compounds with potential anticancer activity
    • Silva, B. V.; Ribeiro, N. M.; Pinto, A. C.; Vargas, M. D.; Dias, L. C. Synthesis of ferrocenyl oxindole compounds with potential anticancer activity. J. Braz. Chem. Soc., 2008, 19, 1244-1247.
    • (2008) J. Braz. Chem. Soc , vol.19 , pp. 1244-1247
    • Silva, B.V.1    Ribeiro, N.M.2    Pinto, A.C.3    Vargas, M.D.4    Dias, L.C.5
  • 80
    • 0037435046 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions
    • Jordan, V.C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions. J. Med. Chem., 2003, 46, 883-908.
    • (2003) J. Med. Chem , vol.46 , pp. 883-908
    • Jordan, V.C.1
  • 81
    • 0037468902 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents
    • Jordan, V.C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents. J. Med. Chem., 2003, 46, 1081-1111.
    • (2003) J. Med. Chem , vol.46 , pp. 1081-1111
    • Jordan, V.C.1
  • 82
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau, A. K.; Barstad, D.; Loria, P. M.; Cheng, L.; Kushner, P. J. Agard, D. A.; Greene, G. L. The structural basis of estrogen receptor/ coactivator recognition and the antagonism of this interaction by tamoxifen. Cell, 1998, 95, 927-937.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 84
    • 0029920454 scopus 로고    scopus 로고
    • Ferrocenyl hydroxytamoxifen: A prototype for a new range of oestradiol receptor site-directed cytotoxics
    • Top, S.; Tang, J.; Vessières, A.; Carrez, D.; Provot, C.; Jaouen, G. Ferrocenyl hydroxytamoxifen: a prototype for a new range of oestradiol receptor site-directed cytotoxics. Chem. Commun., 1996, 8, 955-956.
    • (1996) Chem. Commun , vol.8 , pp. 955-956
    • Top, S.1    Tang, J.2    Vessières, A.3    Carrez, D.4    Provot, C.5    Jaouen, G.6
  • 85
    • 4444267124 scopus 로고    scopus 로고
    • The first organometallic selective estrogen receptor modulators (SERMs) and their relevance to breast cancer
    • Jaouen, G.; Top, S.; Vessieres, A.; Leclercq, G.; McGlinchey, M. J. The first organometallic selective estrogen receptor modulators (SERMs) and their relevance to breast cancer. Curr. Med. Chem. 2004, 11, 2505-2517.
    • (2004) Curr. Med. Chem , vol.11 , pp. 2505-2517
    • Jaouen, G.1    Top, S.2    Vessieres, A.3    Leclercq, G.4    McGlinchey, M.J.5
  • 86
    • 37149018362 scopus 로고    scopus 로고
    • Ferrocifens and Ferrocifenols as new potential weapons against breast cancer
    • Nguyen, A.; Vessieres, A.; Hillard, E. A.; Top, S.; Pigeon, P. Jaouen, G. Ferrocifens and Ferrocifenols as new potential weapons against breast cancer. Chimia, 2007, 61, 716-724.
    • (2007) Chimia , vol.61 , pp. 716-724
    • Nguyen, A.1    Vessieres, A.2    Hillard, E.A.3    Top, S.4    Pigeon, P.5    Jaouen, G.6
  • 87
    • 35548950864 scopus 로고    scopus 로고
    • The influence of phenolic hydroxy substitution on the electron transfer and anti-cancer properties of compounds based on the 2-ferrocenyl-1-phenyl-but-1-ene motif
    • Hillard, E. A.; Pigeon, P.; Vessieres, A.; Amatore, C.; Jaouen, G. The influence of phenolic hydroxy substitution on the electron transfer and anti-cancer properties of compounds based on the 2-ferrocenyl-1-phenyl-but-1-ene motif. Dalton Trans., 2007, 43, 5073-5081.
    • (2007) Dalton Trans , vol.43 , pp. 5073-5081
    • Hillard, E.A.1    Pigeon, P.2    Vessieres, A.3    Amatore, C.4    Jaouen, G.5
  • 88
    • 29544436942 scopus 로고    scopus 로고
    • Ferrocene-mediated proton-coupled electron transfer in a series of ferrocifen-type breast-cancer drug candidates
    • Hillard, E.; Vessieres, A.; Thouin, L.; Jaouen, G.; Amatore, C. Ferrocene-mediated proton-coupled electron transfer in a series of ferrocifen-type breast-cancer drug candidates. Angew. Chem., Int. Ed., 2006, 45, 285-290.
    • (2006) Angew. Chem., Int. Ed , vol.45 , pp. 285-290
    • Hillard, E.1    Vessieres, A.2    Thouin, L.3    Jaouen, G.4    Amatore, C.5
  • 89
    • 0033958868 scopus 로고    scopus 로고
    • 4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides
    • Fan, P.W.; Zhang, F.; Bolton, J.L. 4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides. Chem. Res. Toxicol., 2000, 13, 45-52.
    • (2000) Chem. Res. Toxicol , vol.13 , pp. 45-52
    • Fan, P.W.1    Zhang, F.2    Bolton, J.L.3
  • 90
    • 0033970909 scopus 로고    scopus 로고
    • Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone
    • Zhang, F.; Fan, P. W.; Liu, X.; Shen, L.; van Breemen, R. B.; Bolton, J. L. Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone. Chem. Res. Toxicol., 2000, 13, 53-62.
    • (2000) Chem. Res. Toxicol , vol.13 , pp. 53-62
    • Zhang, F.1    Fan, P.W.2    Liu, X.3    Shen, L.4    van Breemen, R.B.5    Bolton, J.L.6
  • 91
    • 0033135051 scopus 로고    scopus 로고
    • Mutagenic Potential of -(N2-Deoxyguanosinyl)tamoxifen lesions, the major DNA adducts detected in endometrial tissues of patients treated with tamoxifen
    • Terashima, I.; Suzuki, N.; Shibutani, S. Mutagenic Potential of - (N2-Deoxyguanosinyl)tamoxifen lesions, the major DNA adducts detected in endometrial tissues of patients treated with tamoxifen. Cancer Res., 1999, 59, 2091-2095.
    • (1999) Cancer Res , vol.59 , pp. 2091-2095
    • Terashima, I.1    Suzuki, N.2    Shibutani, S.3
  • 92
    • 17444395612 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior
    • Pigeon, P.; Top, S.; Vessières, A.; Huché, M.; Hillard, E. A.; Salomon, E.; Jaouen, G. Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior. J. Med. Chem., 2005, 48, 2814-2821.
    • (2005) J. Med. Chem , vol.48 , pp. 2814-2821
    • Pigeon, P.1    Top, S.2    Vessières, A.3    Huché, M.4    Hillard, E.A.5    Salomon, E.6    Jaouen, G.7
  • 94
    • 41149158678 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of the first ferrocenyl-arylhydantoin derivatives of the nonsteroidal antiandrogen nilutamide
    • Payen, O.; Top, S.; Vessires, A.; Brul, E.; Plamont, M.-A.; McGlinchey, M. J.; Mller-Bunz, H.; Jaouen, G. Synthesis and structure-activity relationships of the first ferrocenyl-arylhydantoin derivatives of the nonsteroidal antiandrogen nilutamide. J. Med. Chem., 2008, 51, 1791-1799.
    • (2008) J. Med. Chem , vol.51 , pp. 1791-1799
    • Payen, O.1    Top, S.2    Vessires, A.3    Brul, E.4    Plamont, M.-A.5    McGlinchey, M.J.6    Mller-Bunz, H.7    Jaouen, G.8
  • 95
    • 9844247985 scopus 로고    scopus 로고
    • Synthesis and antimalarial activity in vitro and in vivo of a new ferrocenechloroquine analogue
    • Biot, C.; Glorian, G.; Maciejewski, L. A.; Brocard, J. S. Synthesis and antimalarial activity in vitro and in vivo of a new ferrocenechloroquine analogue. J. Med. Chem., 1997, 40, 3715-3718.
    • (1997) J. Med. Chem , vol.40 , pp. 3715-3718
    • Biot, C.1    Glorian, G.2    Maciejewski, L.A.3    Brocard, J.S.4
  • 96
    • 8644263983 scopus 로고    scopus 로고
    • 5-substituted tetrazoles as bioisosteres of carboxylic acids. Bioisosterism and mechanistic studies on glutathione reductase inhibitors as antimalarials
    • Biot, C.; Bauer, H.; Schirmer, R. H.; Davioud-Charvet, E. 5-substituted tetrazoles as bioisosteres of carboxylic acids. Bioisosterism and mechanistic studies on glutathione reductase inhibitors as antimalarials. J. Med. Chem., 2004, 47, 5972-5983.
    • (2004) J. Med. Chem , vol.47 , pp. 5972-5983
    • Biot, C.1    Bauer, H.2    Schirmer, R.H.3    Davioud-Charvet, E.4
  • 98
    • 0033762883 scopus 로고    scopus 로고
    • Novel ferrocenic artemisinin derivatives: Synthesis, in vitro antimalarial activity and affinity of binding with ferroprotoporphyrin IX
    • Delhaes, L.; Biot, C.; Berry, L.; Maciejewski, L. A.; Camus, D.; Brocard, J. S.; Dive, D. Novel ferrocenic artemisinin derivatives: synthesis, in vitro antimalarial activity and affinity of binding with ferroprotoporphyrin IX. Bioorg. Med. Chem., 2000, 8, 2739-2745.
    • (2000) Bioorg. Med. Chem , vol.8 , pp. 2739-2745
    • Delhaes, L.1    Biot, C.2    Berry, L.3    Maciejewski, L.A.4    Camus, D.5    Brocard, J.S.6    Dive, D.7
  • 99
    • 0031041266 scopus 로고    scopus 로고
    • Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX
    • Paitayatat, S.; Tarnchompoo, B.; Thebtaranonth, Y.; Yuthavong, Y. Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX. J. Med. Chem., 1997, 40, 633-638.
    • (1997) J. Med. Chem , vol.40 , pp. 633-638
    • Paitayatat, S.1    Tarnchompoo, B.2    Thebtaranonth, Y.3    Yuthavong, Y.4
  • 101
    • 0242684594 scopus 로고    scopus 로고
    • In vitro susceptibility to a new antimalarial organometallic analogue, ferroquine, of Plasmodium falciparum isolates from the Haut-Ogooué region of Gabon
    • Atteke, C.; Ndong, J. M.; Aubouy, A.; Maciejewski, L.; Brocard, J.; Lébibi, J.; Deloron, P. In vitro susceptibility to a new antimalarial organometallic analogue, ferroquine, of Plasmodium falciparum isolates from the Haut-Ogooué region of Gabon. J. Antimicrob. Chemother., 2003, 51, 1021-1024.
    • (2003) J. Antimicrob. Chemother , vol.51 , pp. 1021-1024
    • Atteke, C.1    Ndong, J.M.2    Aubouy, A.3    Maciejewski, L.4    Brocard, J.5    Lébibi, J.6    Deloron, P.7
  • 102
    • 34547624857 scopus 로고    scopus 로고
    • In vitro activity of ferroquine (SSR 97193) against Plasmodium falciparum isolates from the Thai-Burmese border
    • Barends, M.; Jaidee, A.; Khaohirun, N.; Singhasivanon, P.; Nosten, F. In vitro activity of ferroquine (SSR 97193) against Plasmodium falciparum isolates from the Thai-Burmese border. Malar. J., 2007, 6, 81.
    • (2007) Malar. J , vol.6 , pp. 81
    • Barends, M.1    Jaidee, A.2    Khaohirun, N.3    Singhasivanon, P.4    Nosten, F.5
  • 103
    • 3142594018 scopus 로고    scopus 로고
    • The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum
    • Chim, P.; Lim, P.; Sem, R.; Nhem, S.; Maciejewski, L.; Fandeur, T. The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum. Ann. Trop. Med. Parasitol., 2004, 98, 419-424.
    • (2004) Ann. Trop. Med. Parasitol , vol.98 , pp. 419-424
    • Chim, P.1    Lim, P.2    Sem, R.3    Nhem, S.4    Maciejewski, L.5    Fandeur, T.6
  • 104
    • 35649010451 scopus 로고    scopus 로고
    • In vitro activity of ferroquine (SAR97193) is independent of chloroquine resistance in Plasmodium falciparum
    • Kreidenweiss, A.; Kremsner, P. G.; Dietz, K.; Mordmüller, B. In vitro activity of ferroquine (SAR97193) is independent of chloroquine resistance in Plasmodium falciparum. Am. J. Trop. Med. Hyg., 2006, 75, 1178-1181.
    • (2006) Am. J. Trop. Med. Hyg , vol.75 , pp. 1178-1181
    • Kreidenweiss, A.1    Kremsner, P.G.2    Dietz, K.3    Mordmüller, B.4
  • 105
    • 0034883927 scopus 로고    scopus 로고
    • Ferrocene-chloroquine analogues as antimalarial agents: In vitro activity of ferrochloroquine against 103 Gabonese isolates of Plasmodium falciparum
    • Pradines, B.; Fusai, T.; Daries, W.; Laloge, V.; Rogier, C.; Millet, P.; Panconi, E.; Kombila, M.; Parzy, D. Ferrocene-chloroquine analogues as antimalarial agents: in vitro activity of ferrochloroquine against 103 Gabonese isolates of Plasmodium falciparum. J. Antimicrob. Chemother., 2001, 48, 179-184.
    • (2001) J. Antimicrob. Chemother , vol.48 , pp. 179-184
    • Pradines, B.1    Fusai, T.2    Daries, W.3    Laloge, V.4    Rogier, C.5    Millet, P.6    Panconi, E.7    Kombila, M.8    Parzy, D.9
  • 108
    • 0033398868 scopus 로고    scopus 로고
    • Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds
    • Biot, C.; Delhaes, L.; N'Diaye, C. M.; Maciejewski, L. A.; Camus, D.; Dive, D.; Brocard, J. S. Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorg. Med. Chem., 1999, 7, 2843-2847.
    • (1999) Bioorg. Med. Chem , vol.7 , pp. 2843-2847
    • Biot, C.1    Delhaes, L.2    N'Diaye, C.M.3    Maciejewski, L.A.4    Camus, D.5    Dive, D.6    Brocard, J.S.7
  • 109
    • 33646449766 scopus 로고    scopus 로고
    • Design and synthesis of hydroxyferroquine derivatives with antimalarial and antiviral activities
    • Biot, C.; Daher, W.; Chavain, N.; Fandeur, T.; Khalife, J.; Dive, D.; De Clercq, E. Design and synthesis of hydroxyferroquine derivatives with antimalarial and antiviral activities. J. Med. Chem., 2006, 49, 2845-2849.
    • (2006) J. Med. Chem , vol.49 , pp. 2845-2849
    • Biot, C.1    Daher, W.2    Chavain, N.3    Fandeur, T.4    Khalife, J.5    Dive, D.6    de Clercq, E.7
  • 110
    • 35648986600 scopus 로고    scopus 로고
    • Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues
    • Biot, C.; Pradines, B.; Sergeant, M. H.; Gut, J.; Rosenthal, P. J.; Chibale, K. Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues. Bioorg. Med. Chem. Lett., 2007, 17, 6434-6438.
    • (2007) Bioorg. Med. Chem. Lett , vol.17 , pp. 6434-6438
    • Biot, C.1    Pradines, B.2    Sergeant, M.H.3    Gut, J.4    Rosenthal, P.J.5    Chibale, K.6
  • 111
    • 71849091387 scopus 로고    scopus 로고
    • Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker
    • Chavain, N.; Davioud-Charvet, E.; Trivelli, X.; Mbeki, L.; Rottmann, M.; Brun, R.; Biot, C. Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker. Bioorg. Med. Chem., 2009, 17, 8048-8059.
    • (2009) Bioorg. Med. Chem , vol.17 , pp. 8048-8059
    • Chavain, N.1    Davioud-Charvet, E.2    Trivelli, X.3    Mbeki, L.4    Rottmann, M.5    Brun, R.6    Biot, C.7
  • 112
    • 73249120807 scopus 로고    scopus 로고
    • Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach
    • in press
    • Dubar, F.; Anquetin, G.; Pradines, B.; Dive, D.; Khalife, J.; Biot, C. Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach. J. Med. Chem., 2009, in press.
    • (2009) J. Med. Chem
    • Dubar, F.1    Anquetin, G.2    Pradines, B.3    Dive, D.4    Khalife, J.5    Biot, C.6
  • 113
    • 0036700515 scopus 로고    scopus 로고
    • Unsymmetrical 1,1'-disubstituted Ferrocenes: Synthesis of Co(ii), Cu(ii), Ni(ii) and Zn(ii) Chelates of Ferrocenyl -1-thiadiazolo-1'-tetrazole, -1- thiadiazolo-1'-triazole and -1-tetrazolo-1'-triazole with Antimicrobial Properties
    • Chohan, Z. H.; Scozzafava, A.; Supuran, C. T. Unsymmetrical 1,1'-disubstituted Ferrocenes: Synthesis of Co(ii), Cu(ii), Ni(ii) and Zn(ii) Chelates of Ferrocenyl -1-thiadiazolo-1'-tetrazole, -1- thiadiazolo-1'-triazole and -1-tetrazolo-1'-triazole with Antimicrobial Properties. J. Enzyme Inhib. Med. Chem., 2002, 17, 261-266.
    • (2002) J. Enzyme Inhib. Med. Chem , vol.17 , pp. 261-266
    • Chohan, Z.H.1    Scozzafava, A.2    Supuran, C.T.3
  • 115
    • 0021209864 scopus 로고
    • Pyrrolnitrin analogues. IX. Synthesis and biological activity of 1-tolyl-3-nitrophenyl-5-methylpyrazole-4-carboxylic acids and 1-tolyl-3-methyl-5-nitrophenylpyrazole-4-carboxylic acids
    • Cecchi, L.; Melani, F.; Palazzino, G.; Filacchioni, G.; Porretta, G. C. Pyrrolnitrin analogues. IX. Synthesis and biological activity of 1-tolyl-3-nitrophenyl-5-methylpyrazole-4-carboxylic acids and 1-tolyl-3-methyl-5-nitrophenylpyrazole-4-carboxylic acids. Il FARMACO. 1984, 39, 888-900.
    • (1984) Il FARMACO , vol.39 , pp. 888-900
    • Cecchi, L.1    Melani, F.2    Palazzino, G.3    Filacchioni, G.4    Porretta, G.C.5
  • 116
    • 0021739334 scopus 로고
    • Pyrrolnitrin analogues. X. Synthesis and biological activity of 1-chlorophenyl- 3- or 5-nitrophenyl-pyrazole-4-carboxylic acids
    • Cecchi, L.; Melani, F.; Palazzino, G.; Filacchioni, G. Pyrrolnitrin analogues. X. Synthesis and biological activity of 1-chlorophenyl- 3- or 5-nitrophenyl-pyrazole-4-carboxylic acids. Il FARMACO. 1984, 39, 953-962.
    • (1984) Il FARMACO , vol.39 , pp. 953-962
    • Cecchi, L.1    Melani, F.2    Palazzino, G.3    Filacchioni, G.4
  • 117
    • 0343081482 scopus 로고    scopus 로고
    • Synthesis, characterization and pharmacological properties of some 4-arylhydrazono-2-pyrazoline-5-one derivatives obtained from heterocyclic amines
    • Küçükgüzel, G.; Rollas, S.; Erdeniz, H.; Kiraz, M.; Ekinci, A. C.; Vidin, A. Synthesis, characterization and pharmacological properties of some 4-arylhydrazono-2-pyrazoline-5-one derivatives obtained from heterocyclic amines. Eur. J. Med. Chem., 2000, 35, 761-771.
    • (2000) Eur. J. Med. Chem , vol.35 , pp. 761-771
    • Küçükgüzel, G.1    Rollas, S.2    Erdeniz, H.3    Kiraz, M.4    Ekinci, A.C.5    Vidin, A.6
  • 119
    • 0037366533 scopus 로고    scopus 로고
    • Design and synthesis of some substituted 1H-pyrazolylthiazolo[ 4,5-d]pyrimidines as anti-inflammatory-antimicrobial Agents
    • Fahmy, H. T. Y.; Rostom, S. A. F.; Baraka, A. M. Design and synthesis of some substituted 1H-pyrazolylthiazolo[ 4,5-d]pyrimidines as anti-inflammatory-antimicrobial Agents. Eur. J. Med. Chem., 2003, 38, 27-36.
    • (2003) Eur. J. Med. Chem , vol.38 , pp. 27-36
    • Fahmy, H.T.Y.1    Rostom, S.A.F.2    Baraka, A.M.3
  • 120
    • 34548794722 scopus 로고    scopus 로고
    • Synthesis of ferrocenyl pyrazoles by the reaction of (2-formyl-1-chlorovinyl)ferrocene with hydrazines
    • Zora, M.; Gormen, M. Synthesis of ferrocenyl pyrazoles by the reaction of (2-formyl-1-chlorovinyl)ferrocene with hydrazines. J. Organomet. Chem., 2007, 692, 5026-5032.
    • (2007) J. Organomet. Chem , vol.692 , pp. 5026-5032
    • Zora, M.1    Gormen, M.2
  • 121
    • 36749015596 scopus 로고    scopus 로고
    • Synthesis of ferrocenyl pyrazoles by the reaction of 3- ferrocenylpropynal with hydrazinium salts
    • Zora, M.; Pinar, A. N.; Odabaosoglu, M.; Büyükgüngör, O.; Turgut, G. Synthesis of ferrocenyl pyrazoles by the reaction of 3- ferrocenylpropynal with hydrazinium salts. J. Organomet. Chem., 2008, 693, 145-154.
    • (2008) J. Organomet. Chem , vol.693 , pp. 145-154
    • Zora, M.1    Pinar, A.N.2    Odabaosoglu, M.3    Büyükgüngör, O.4    Turgut, G.5
  • 124
    • 26644467705 scopus 로고    scopus 로고
    • Antibacterial activities of ferrocenoyl- and cobaltoceniumpeptide bioconjugates
    • Chantson, J. T.; Falzacappa, M. V. V.; Crovella, S.; Metzler-Nolte, N. Antibacterial activities of ferrocenoyl- and cobaltoceniumpeptide bioconjugates. J. Organomet. Chem., 2005, 690, 4564-4572.
    • (2005) J. Organomet. Chem , vol.690 , pp. 4564-4572
    • Chantson, J.T.1    Falzacappa, M.V.V.2    Crovella, S.3    Metzler-Nolte, N.4
  • 125
    • 33751207736 scopus 로고    scopus 로고
    • Solid-phase synthesis, characterization, and antibacterial activities of metallocene-peptide bioconjugates
    • Chantson, J. T.; Falzacappa, M. V. V.; Crovella, S.; Metzler-Nolte, N. Solid-phase synthesis, characterization, and antibacterial activities of metallocene-peptide bioconjugates. Chem Med Chem, 2006, 1, 1268-1274.
    • (2006) Chem Med Chem , vol.1 , pp. 1268-1274
    • Chantson, J.T.1    Falzacappa, M.V.V.2    Crovella, S.3    Metzler-Nolte, N.4
  • 126
    • 0037057547 scopus 로고    scopus 로고
    • Studies: Rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists
    • Bettinetti, L.; Schlotter, K.; Hübner, H.; Gmeiner, P. Interactive SAR studies: Rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. J. Med. Chem., 2002, 45, 4594-4597.
    • (2002) J. Med. Chem , vol.45 , pp. 4594-4597
    • Bettinetti, L.1    Schlotter, K.2    Hübner, H.3    Gmeiner, P.4    Interactive, S.A.R.5
  • 127
    • 0043264004 scopus 로고    scopus 로고
    • Attenuation of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) neurotoxicity by the novel selective dopamine D3-receptor partial agonist FAUC 329 predominantly in the nucleus accumbens of mice
    • Boeckler, F.; Leng, A.; Mura, A.; Bettinetti, L.; Feldon, J.; Gmeiner, P.; Ferger, B. Attenuation of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) neurotoxicity by the novel selective dopamine D3-receptor partial agonist FAUC 329 predominantly in the nucleus accumbens of mice. Biochem. Pharmacol., 2003, 66, 1025-1032.
    • (2003) Biochem. Pharmacol , vol.66 , pp. 1025-1032
    • Boeckler, F.1    Leng, A.2    Mura, A.3    Bettinetti, L.4    Feldon, J.5    Gmeiner, P.6    Ferger, B.7
  • 128
    • 0035899181 scopus 로고    scopus 로고
    • Rationally Based Efficacy Tuning of Selective Dopamine D4 Receptor Ligands Leading to the Complete Antagonist 2-[4-(4-Chlorophenyl) piperazin-1- ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213)
    • Löber, S.; Hübner, H.; Utz, W.; Gmeiner, P. Rationally Based Efficacy Tuning of Selective Dopamine D4 Receptor Ligands Leading to the Complete Antagonist 2-[4-(4-Chlorophenyl) piperazin-1- ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213). J. Med. Chem., 2001, 44, 2691-2694.
    • (2001) J. Med. Chem , vol.44 , pp. 2691-2694
    • Löber, S.1    Hübner, H.2    Utz, W.3    Gmeiner, P.4
  • 129
    • 4544380870 scopus 로고    scopus 로고
    • FAUC 213, a highly selective dopamine D 4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia
    • Boeckler, F.; Russig, H.; Zhang, W.; Löber, S.; Schetz, J.; Hübner, H.; Ferger, B.; Gmeiner, P.; Feldon, J. FAUC 213, a highly selective dopamine D 4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia. Psychopharmacology, 2004, 175, 7-17.
    • (2004) Psychopharmacology , vol.175 , pp. 7-17
    • Boeckler, F.1    Russig, H.2    Zhang, W.3    Löber, S.4    Schetz, J.5    Hübner, H.6    Ferger, B.7    Gmeiner, P.8    Feldon, J.9
  • 130
    • 20144375764 scopus 로고    scopus 로고
    • Fancy Bioisosteres: Metallocene-derived G-Protein-coupled receptor ligands with subnanomolar binding affinity and novel selectivity profiles
    • Schlotter, K.; Boeckler, F.; Hübner, H.; Gmeiner, P. Fancy Bioisosteres: Metallocene-derived G-Protein-coupled receptor ligands with subnanomolar binding affinity and novel selectivity profiles. J. Med. Chem., 2005, 48, 3696-3699.
    • (2005) J. Med. Chem , vol.48 , pp. 3696-3699
    • Schlotter, K.1    Boeckler, F.2    Hübner, H.3    Gmeiner, P.4
  • 131
    • 36148959779 scopus 로고    scopus 로고
    • Chapter 32. The use of bioisosteric groups in lead optimization
    • Chen, X.; Wang, W. Chapter 32. The use of bioisosteric groups in lead optimization. Annu. Rep. Med. Chem., 2003, 38, 333-346.
    • (2003) Annu. Rep. Med. Chem , vol.38 , pp. 333-346
    • Chen, X.1    Wang, W.2
  • 132
    • 33745384809 scopus 로고    scopus 로고
    • From bench to bedside - preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A)
    • Hartinger, C. G.; Zorbas-Seifried, S.; Jakupec, M. A.; Kynast, B.; Zorbas, H.; Keppler, B. K. From bench to bedside - preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A). J. Inorg. Biochem., 2006, 100, 891-904.
    • (2006) J. Inorg. Biochem , vol.100 , pp. 891-904
    • Hartinger, C.G.1    Zorbas-Seifried, S.2    Jakupec, M.A.3    Kynast, B.4    Zorbas, H.5    Keppler, B.K.6
  • 134
    • 4043115636 scopus 로고    scopus 로고
    • Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro humour invasion
    • Bergamo, A.; Stocco, G.; Casarsa, C.; Cocchietto, M.; Alessio, E.; Serli, B.; Zorzet, S.; Sava, G. Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro humour invasion. Int. J. Oncol., 2004, 24, 373-379.
    • (2004) Int. J. Oncol , vol.24 , pp. 373-379
    • Bergamo, A.1    Stocco, G.2    Casarsa, C.3    Cocchietto, M.4    Alessio, E.5    Serli, B.6    Zorzet, S.7    Sava, G.8
  • 135
    • 0036725330 scopus 로고    scopus 로고
    • Half-Sandwich complexes with aminocarboxylate ligands and their use as enantioselective hydrogen transfer catalysts
    • Carmona, D.; Lamata, M. P.; Oro, L. A. Half-Sandwich complexes with aminocarboxylate ligands and their use as enantioselective hydrogen transfer catalysts. Eur. J. Inorg. Chem., 2002, 9, 2239-2251.
    • (2002) Eur. J. Inorg. Chem , vol.9 , pp. 2239-2251
    • Carmona, D.1    Lamata, M.P.2    Oro, L.A.3
  • 136
    • 1242331871 scopus 로고    scopus 로고
    • Synthesis and Chemical-Pharmacological Characterization of the Antimetastatic NAMI-A-Type Ru(III) Complexes (Hdmtp)[trans- RuCl4(dmso-S)(dmtp)], (Na)[trans-RuCl4(dmso-S)(dmtp)], and [mer-RuCl3(H2O)(dmso-S)(dmtp)] (dmtp = 5,7- Dimethyl[1,2,4]triazolo[1,5-a]pyrimidine)
    • Velders, A. H.; Bergamo, A.; Alessio, E.; Zangrando, E.; Haasnoot, J. G.; Casarsa, C.; Cocchietto, M.; Zorzet, S.; Sava, G. Synthesis and Chemical-Pharmacological Characterization of the Antimetastatic NAMI-A-Type Ru(III) Complexes (Hdmtp)[trans- RuCl4(dmso-S)(dmtp)], (Na)[trans-RuCl4(dmso-S)(dmtp)], and [mer-RuCl3(H2O)(dmso-S)(dmtp)] (dmtp = 5,7- Dimethyl[1,2,4]triazolo[1,5-a]pyrimidine). J. Med. Chem., 2004, 47, 1110-1121.
    • (2004) J. Med. Chem , vol.47 , pp. 1110-1121
    • Velders, A.H.1    Bergamo, A.2    Alessio, E.3    Zangrando, E.4    Haasnoot, J.G.5    Casarsa, C.6    Cocchietto, M.7    Zorzet, S.8    Sava, G.9
  • 137
    • 0026513746 scopus 로고
    • Studies on DNA damage and induction of SOS repair by novel multifunctional bioreducible compounds. II. A metronidazole adduct of a ruthenium-arene compound
    • Dale, L. D.; Tocher, J. H.; Dyson, T. M.; Edwards, D. I.; Tocher, D. A. Studies on DNA damage and induction of SOS repair by novel multifunctional bioreducible compounds. II. A metronidazole adduct of a ruthenium-arene compound. Anti-Cancer Drug Des., 1992, 7, 3-14.
    • (1992) Anti-Cancer Drug Des , vol.7 , pp. 3-14
    • Dale, L.D.1    Tocher, J.H.2    Dyson, T.M.3    Edwards, D.I.4    Tocher, D.A.5
  • 140
    • 53349169299 scopus 로고    scopus 로고
    • Influence of the diketonato ligand on the cytotoxicities of [Ru(6-p-cymene)(R2acac)(PTA)]+ complexes (PTA = 1,3,5-triaza-7-phosphaadamantane)
    • Vock, C. A. Anna K. Renfrew, Rosario Scopelliti, Lucienne Juillerat-Jeanneret, Paul J. Dyson. Influence of the diketonato ligand on the cytotoxicities of [Ru(6-p-cymene)(R2acac)(PTA)]+ complexes (PTA = 1,3,5-triaza-7-phosphaadamantane). Eur. J. Inorg. Chem., 2008, 10, 1661-1671.
    • (2008) Eur. J. Inorg. Chem , vol.10 , pp. 1661-1671
    • Vock, C.A.1    Renfrew, K.A.2    Scopelliti, R.3    Juillerat-Jeanneret, L.4    Dyson, P.J.5
  • 147
    • 33746110095 scopus 로고    scopus 로고
    • New principles in medicinal organometallic chemistry
    • Schatzschneider, U.; Metzler-Nolte, N. New principles in medicinal organometallic chemistry. Angew. Chem. Int. Ed., 2006, 45, 1504-1507.
    • (2006) Angew. Chem. Int. Ed , vol.45 , pp. 1504-1507
    • Schatzschneider, U.1    Metzler-Nolte, N.2
  • 153
    • 38049161291 scopus 로고    scopus 로고
    • Highly antiproliferative ruthenium(II) and osmium(II) arene complexes with paullone-derived ligands
    • Schmid, W. F.; John, R. O.; Arion, V. B.; Jakupec, M. A.; Keppler, B. K. Highly antiproliferative ruthenium(II) and osmium(II) arene complexes with paullone-derived ligands. Organometallics, 2007, 26, 6643-6652.
    • (2007) Organometallics , vol.26 , pp. 6643-6652
    • Schmid, W.F.1    John, R.O.2    Arion, V.B.3    Jakupec, M.A.4    Keppler, B.K.5
  • 155
    • 27744556942 scopus 로고    scopus 로고
    • Ruthenium (II)-derived organometallic compounds induce cytostatic and cytotoxic effects on mammalian cancer cell lines through p53-dependent and p53-independent mechanisms
    • Gaiddon, C.; Jeannequin, P.; Bischoff, P.; Pfeffer, M.; Sirlin, C.; Loeffler, J. P. Ruthenium (II)-derived organometallic compounds induce cytostatic and cytotoxic effects on mammalian cancer cell lines through p53-dependent and p53-independent mechanisms. J. Pharmacol. Exp. Ther., 2005, 315, 1403-1411.
    • (2005) J. Pharmacol. Exp. Ther , vol.315 , pp. 1403-1411
    • Gaiddon, C.1    Jeannequin, P.2    Bischoff, P.3    Pfeffer, M.4    Sirlin, C.5    Loeffler, J.P.6
  • 156
    • 64349112979 scopus 로고    scopus 로고
    • Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives
    • Van Rijt, S. H.; Peacock, A. F. A.; Johnstone, R. D. L.; Parsons, S.; Sadler, P. J. Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives. Inorg. Chem., 2009, 48, 1753-1762.
    • (2009) Inorg. Chem , vol.48 , pp. 1753-1762
    • van Rijt, S.H.1    Peacock, A.F.A.2    Johnstone, R.D.L.3    Parsons, S.4    Sadler, P.J.5
  • 159
    • 39249084976 scopus 로고    scopus 로고
    • Gold(III) compounds as anticancer agents: Relevance of gold-protein interactions for their mechanism of action
    • Casini, A.; Hartinger, C.; Gabbiani, C.; Mini, E.; Dyson, P. J.; Keppler, B. K.; Messori, L. Gold(III) compounds as anticancer agents: Relevance of gold-protein interactions for their mechanism of action. J. Inorg. Biochem., 2008, 102, 564-575.
    • (2008) J. Inorg. Biochem , vol.102 , pp. 564-575
    • Casini, A.1    Hartinger, C.2    Gabbiani, C.3    Mini, E.4    Dyson, P.J.5    Keppler, B.K.6    Messori, L.7
  • 160
    • 0014691619 scopus 로고
    • Platinum compounds: A new class of potent antitumour agents
    • Rosenberg, B.; VanCamp, L.; Trosko, J. E.; Mansour, V.H. Platinum compounds: A new class of potent antitumour agents. Nature, 1969, 222, 385-386.
    • (1969) Nature , vol.222 , pp. 385-386
    • Rosenberg, B.1    Vancamp, L.2    Trosko, J.E.3    Mansour, V.H.4
  • 162
    • 24644486532 scopus 로고    scopus 로고
    • Current Status Of Platinum-Based Antitumor Drugs
    • Wong, E.; Giandomenico, C. M. Current Status Of Platinum-Based Antitumor Drugs. Chem. Rev., 1999, 99, 2451-2466.
    • (1999) Chem. Rev , vol.99 , pp. 2451-2466
    • Wong, E.1    Giandomenico, C.M.2
  • 163
    • 0036268977 scopus 로고    scopus 로고
    • Gold derivatives for the treatment of cancer
    • Tiekink, E.R. Gold derivatives for the treatment of cancer. Crit. Rev. Oncol. Hematol., 2002, 42, 225-248.
    • (2002) Crit. Rev. Oncol. Hematol , vol.42 , pp. 225-248
    • Tiekink, E.R.1
  • 166
    • 0002752996 scopus 로고    scopus 로고
    • Gold(III) compounds as potential antitumor agents: Cytotoxicity and DNA binding properties of some selected polyamine-gold(III) complexes
    • Carotti, S.; Guerri, A.; Mazzei, T.; Messori, L.; Mini, E.; Orioli, P. Gold(III) compounds as potential antitumor agents: Cytotoxicity and DNA binding properties of some selected polyamine-gold(III) complexes. Inorg. Chim. Acta, 1998, 281, 90-94.
    • (1998) Inorg. Chim. Acta , vol.281 , pp. 90-94
    • Carotti, S.1    Guerri, A.2    Mazzei, T.3    Messori, L.4    Mini, E.5    Orioli, P.6
  • 167
    • 0034699549 scopus 로고    scopus 로고
    • Gold(III) Complexes as Potential Antitumor Agents: Solution chemistry and cytotoxic properties of some selected gold(III) compounds
    • Messori, L.; Abbate, F.; Marcon, G.; Orioli, P.; Fontani, M.; Mini, E.; Mazzei, T.; Carotti, S.; O'Connell, T.; Zanello, P. Gold(III) Complexes as Potential Antitumor Agents: Solution chemistry and cytotoxic properties of some selected gold(III) compounds. J. Med. Chem., 2000, 43, 3541-3548.
    • (2000) J. Med. Chem , vol.43 , pp. 3541-3548
    • Messori, L.1    Abbate, F.2    Marcon, G.3    Orioli, P.4    Fontani, M.5    Mini, E.6    Mazzei, T.7    Carotti, S.8    O'Connell, T.9    Zanello, P.10
  • 170
    • 0034704039 scopus 로고    scopus 로고
    • Crystal structure and solution chemistry of the cytotoxic complex 1,2-dichloro(o-phenanthroline)gold(III) chloride
    • Abbate, F.; Orioli, P.; Bruni, B.; Marcon, G.; Messori, L. Crystal structure and solution chemistry of the cytotoxic complex 1,2-dichloro(o-phenanthroline)gold(III) chloride. Inorg. Chim. Acta, 2000, 311, 1-5.
    • (2000) Inorg. Chim. Acta , vol.311 , pp. 1-5
    • Abbate, F.1    Orioli, P.2    Bruni, B.3    Marcon, G.4    Messori, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.