Methoxy-phenyl substituted ansa-titanocenes as potential anti-cancer drugs derived from fulvenes and titanium dichloride

Journal of Inorganic Biochemistry

Volumn 98, Issue 12, 2004, Pages 1987-1994

  Tacke, Matthias ^a   Cuffe, Laurence P ^a   Gallagher, William M ^a   Lou, Ying ^a   Mendoza, Oscar ^a   Müller Bunz, Helge ^a   Rehmann, Franz Josef K ^a   Sweeney, Nigel ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Anti cancer drug; cis Platinum; DFT calculations; Fulvene; LLC PK; Titanocene

Indexed keywords

6 (2',4',6' TRIMETHOXYPHENYL)FULVENE; 6 (3',5' DIMETHOXYPHENYL)FULVENE; 6 (4' METHOXYPHENYL)FULVENE; [1,2 BIS(CYCLOPENTADIENYL) 1,2 BIS(2',4',6' TRIMETHOXYPHENYL)ETHANEDIYL] TITANIUM DICHLORIDE; [1,2 BIS(CYCLOPENTADIENYL) 1,2 BIS(3',5' DIMETHOXYPHENYL)ETHANEDIYL] TITANIUM DICHLORIDE; [1,2 BIS(CYCLOPENTADIENYL) 1,2 BIS(4' METHOXYPHENYL)ETHANEDIYL]TITANIUM DICHLORIDE; ALKENE DERIVATIVE; ANTINEOPLASTIC AGENT; TITANOCENE DICHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL STRAIN; CONTROLLED STUDY; DENSITY FUNCTIONAL THEORY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; KIDNEY CARCINOMA; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CYCLOPENTANES; DRUG EVALUATION, PRECLINICAL; INHIBITORY CONCENTRATION 50; KIDNEY NEOPLASMS; MOLECULAR CONFORMATION; SWINE; TITANIUM;

SUS SCROFA;

EID: 8444227535     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2004.09.001     Document Type: Article

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