Substituent effects on the antibacterial activity of nitrogen-carbon- linked (azolylphenyl)oxazolidinones with expanded activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis

Journal of Medicinal Chemistry

Volumn 43, Issue 5, 2000, Pages 953-970

  Genin, Michael J ^b   Allwine, Debra A ^b   Anderson, David J ^b   Barbachyn, Michael R ^b   Emmert, D Edward ^b   Garmon, Stuart A ^b   Graber, David R ^b   Grega, Kevin C ^b   Hester, Jackson B ^b   Hutchinson, Douglas K ^a,b   Morris, Joel ^b   Reischer, Robert J ^b   Ford, Charles W ^b   Zurenko, Gary E ^b   Hamel, Judith C ^b   Schaadt, Ronda D ^b   Stapert, Douglas ^b   Yagi, Betty H ^b  

^a ABBOTT LABORATORIES   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXAZOLIDINONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; HAEMOPHILUS INFLUENZAE; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; MOUSE; NONHUMAN; STAPHYLOCOCCUS INFECTION; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; AZOLES; HAEMOPHILUS INFLUENZAE; HUMANS; METHICILLIN RESISTANCE; MICE; MICROBIAL SENSITIVITY TESTS; MORAXELLA (BRANHAMELLA) CATARRHALIS; OXAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034624685     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990373e     Document Type: Article

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