Synthesis and cytotoxicity studies of new morpholino-functionalised and N-heteroaryl-substituted titanocene anticancer drugs

Medicinal Chemistry

Volumn 4, Issue 2, 2008, Pages 91-99

  Hogan, M ^a   Claffey, J ^a   Pampillon C ^a   Tacke, Mathias ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Anti cancer drugs; Cis platin; Fulvene; LLC PK; Morpholino functionalised metallocenes; Nitrogen containing heteroaryl substituted metallocenes; RCC; Titanocene

Indexed keywords

ANTINEOPLASTIC METAL COMPLEX; BIS[[MORPHOLINO 2 N (N,N DIMETHYLAMINO)METHYLIMIDAZOLYL]METHYLCYCLOPETADIENYL]TITIANIUM DICHLORIDE; BIS[MORPHOLINO 2 (N METHYL)IMIDAZOLYLMETHYLCYCLOPENTANDIENYL]TITANIUM DICHLORIDE; BIS[MORPHOLINO 2 (N METHYLINDOLYL)METHYLCYCLOPENTADIENYL]TITANIUM DICHLORIDE; CISPLATIN; MORPHOLINE DERIVATIVE; TITANIUM TETRACHLORIDE; TITANOCENE; TITANOCENE DICHLORIDE; ANTINEOPLASTIC AGENT; CYCLOPENTANE DERIVATIVE; FULVENE; ORGANOMETALLIC COMPOUND;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ASSAY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; KIDNEY CELL; LITHIATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SWINE; ANIMAL; CELL STRAIN; CHEMISTRY; SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CYCLOPENTANES; INHIBITORY CONCENTRATION 50; LLC-PK1 CELLS; MORPHOLINES; ORGANOMETALLIC COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 42949166140     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340608783789202     Document Type: Article

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