Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process

Journal of Medicinal Chemistry

Volumn 45, Issue 26, 2002, Pages 5786-5796

  Tabbì, Giovanni ^a   Cassino, Claudio ^b   Cavigiolio, Giorgio ^b   Colangelo, Donato ^b   Ghiglia, Annalisa ^b   Viano, Ilario ^b   Osella, Domenico ^b  

^a CNR   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; BLEOMYCIN; FERROCENE; FERROCENIUM DERIVATIVE; HYDROXYL RADICAL; OXYGEN RADICAL; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CELL COMPARTMENTALIZATION; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DOSE RESPONSE; ELECTRON SPIN RESONANCE; FLUORESCENCE ACTIVATED CELL SORTING; GROWTH INHIBITION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; ULTRAVIOLET SPECTROSCOPY;

ANTINEOPLASTIC AGENTS; BLEOMYCIN; DNA DAMAGE; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG STABILITY; DRUG SYNERGISM; ELECTRON SPIN RESONANCE SPECTROSCOPY; FERROUS COMPOUNDS; FREE RADICALS; HUMANS; OXIDATION-REDUCTION; SPECTROPHOTOMETRY, ULTRAVIOLET; SPIN TRAPPING; TUMOR CELLS, CULTURED; WATER;

EID: 0037137615     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm021003k     Document Type: Article

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