DNA cleaving activity and cytotoxic activity of ferricenium cations

Chemistry Letters

Volumn , Issue 11, 1997, Pages 1177-1178

  Tamura, Hiroshi ^a   Miwa, Masahiro ^a  

^a KANSAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031322560     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.1997.1177     Document Type: Article

References (25)

1. a) Y. Sugiura and T. Kikuchi, J. Antibiot., 31, 1310 (1978).
2. b) P. B. Dervan, Science, 232, 464 (1986).
3. c) C. G. Riordan, and P. Wei, J. Am. Chem. Soc., 116, 2189 (1994).
4. a) R. P. Hertzberg and P. B. Dervan, J. Am. Chem. Soc., 104, 313 (1982).
5. b) R. P. Hertzberg and P. B. Dervan, Biochemistry, 23, 3934 (1984).
6. J. S. Tayor, P. G. Schulta, and P. B. Dervan, Tetrahedron, 40, 457 (1984).
7. a) Y. Matsumoto and M. Komiyama, Chem. Express, 7, 785 (1992).
8. b) M. Komiyama, N. Takeda, Y. Takahashi, H. Uchida, T. Shiiba, T. Kodama, and M. Yashiro, J. Chem. Soc., Perkin Trans., 2, 269 (1995).
9. c) J. Sumaoka, A. Kijimura, M. Ohno, and M. Komiyama, Chem. Lett., 1997, 507.
10. D. W. J. Kwong, O. Y. Chan, R. N. S. Wong, S. M. Husser, L. Vaca, and S. I. Chan, Inorg. Chem., 36, 1276 (1997).
11. S. Hashimoto and Y. Nakamura, J. Chem. Soc., Perkin Trans. 1, 1996, 2623.
12. R. Hettich and H. J. Schneider, J. Am. Chem. Soc., 119, 5638 (1997).
13. T. Itoh, H. Hisada, T. Sumiya, M. Hosono, Y. Usui, and Y. Fujii, Chem. Commun., 1997, 677.
14. a) H. Tamura, H. Imai, J. Kuwahara, and Y. Sugiura, J. Am. Chem. Soc., 109, 6870 (1987).
15. b) H. Tamura and H. Fujita, Chem. Lett., 1997, 711.
16. M. Vogel, M. Rausch, and H. Rosenberg, J. Org. Chem., 22, 1016 (1957).
17. M. D. Rausch and L. E. Coleman, J. Org. Chem., 23, 107 (1958).
18. E. W. Neuse, B. S. Mojapelo, and J. Ensling, Transition Met. Chem., 10, 135 (1985).
19. G. Wilkinson, M. Rosenblum, M. C. Whiting, and R. B. Woodward, J. Am. Chem. Soc., 74, 2125 (1952).
20. A. P. Ginsberg and M. B. Robin, Inorg. Chem. 2, 817 (1963).
21. J. Burchenal, K. Kalaher, K. Dew, and L. Lokys, Cancer Treat. Rep., 63, 1493 (1979).
22. C. K. Mirabelli, R. K. Johnson, D. T. Hill, L. F. Faucette, G. R. Girard, G. Y. Kuo, C. M. Sung, and S. T. Crooke, J. Med. Chem., 29, 218 (1986).
23. A solution of ferricenium cation (25 μM) was immediately added to φX 174 RF I DNA (50 μM in DNA basepair) in 100 mM Tris-HCl, pH 8.0. The reaction was allowed to proceed for 30 min at 37°C, and then DNA was ethanol-precipitated. After resuspension in 100 mM Tris-HCl, pH 8.0, the DNA samples were analyzed by electrophoresis using 1% agarose gel containing 0.5 μg/ml ethidium bromide.
24. T. Ozawa, H. Goto, F. Takazawa, and A. Hanaki, Nippon Kagaku Kaishi, 1988, 459.
25. The isolation of the Fe(II) species was unsuccessful. The attempt is now underway.