Alterations in the mitochondrial regulatory pathways constituted by the nuclear co-factors PGC-1α or PGC-1β and mitofusin 2 in skeletal muscle in type 2 diabetes

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1797, Issue 6-7, 2010, Pages 1028-1033

  Zorzano, Antonio ^a,b,c   Hernández Alvarez, María Isabel ^a,b,c   Palacín, Manuel ^a,b   Mingrone, Geltrude ^d  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d CATHOLIC UNIVERSITY   (Italy)

Author keywords

Insulin resistance; Mitochondrial regulatory pathway; Mitofusin; Skeletal muscle; Type 2 diabetes

Indexed keywords

CITRATE SYNTHASE; MITOCHONDRIAL DNA; MITOFUSIN 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; ROSIGLITAZONE;

AEROBIC METABOLISM; BILIOPANCREATIC BYPASS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HERITABILITY; HUMAN; INSULIN RESISTANCE; MITOCHONDRIAL RESPIRATION; MORBID OBESITY; MUSCLE METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; TREATMENT RESPONSE; WEIGHT REDUCTION;

BILIOPANCREATIC DIVERSION; CARRIER PROTEINS; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; INSULIN RESISTANCE; MEMBRANE PROTEINS; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; OBESITY, MORBID; TRANSCRIPTION FACTORS;

EID: 77953807425     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2010.02.017     Document Type: Review

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