-
1
-
-
0028032895
-
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
-
Araki, E., Lipes, M.A , Patti, M.E., Brüning, J.C., Haag, B., Johnson, R.S. and Kahn, C.R. (1994) Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature, 372, 186-190.
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
Brüning, J.C.4
Haag, B.5
Johnson, R.S.6
Kahn, C.R.7
-
2
-
-
0025847593
-
Molecular detects in diabetes mellitus
-
Bell, G.I. (1991) Molecular detects in diabetes mellitus. Diabetes, 40, 413-422.
-
(1991)
Diabetes
, vol.40
, pp. 413-422
-
-
Bell, G.I.1
-
3
-
-
0021358883
-
Formation of germ-line chimeras from embryo-derived teratocarcinoma cell lines
-
Bradley, A., Martin, M., Kaufman, M.H. and Robertson, E. (1984) Formation of germ-line chimeras from embryo-derived teratocarcinoma cell lines. Nature, 309, 255-256.
-
(1984)
Nature
, vol.309
, pp. 255-256
-
-
Bradley, A.1
Martin, M.2
Kaufman, M.H.3
Robertson, E.4
-
4
-
-
0027520656
-
The diabetogenes concept in NIDDM
-
Efendic, S., Östenson, C.G. and Vranic, M. (eds), Plenum Press, New York
-
De Meyts, P. (1993) The diabetogenes concept in NIDDM. In Efendic, S., Östenson, C.G. and Vranic, M. (eds), New Concepts in the Pathogenesis of NIDDM. Plenum Press, New York, pp. 89-100.
-
(1993)
New Concepts in the Pathogenesis of NIDDM
, pp. 89-100
-
-
De Meyts, P.1
-
5
-
-
0027944978
-
The insulin-like growth factor-I receptor
-
De Meyts, P., Wallach, B., Christoffersen, C.T., Urso, B., Gronskov, K., Latus, L.J., Yakushiji, F., Ilondo, M.M. and Shymko, R.M. (1994) The insulin-like growth factor-I receptor. Hormone Res., 42, 152-169.
-
(1994)
Hormone Res.
, vol.42
, pp. 152-169
-
-
De Meyts, P.1
Wallach, B.2
Christoffersen, C.T.3
Urso, B.4
Gronskov, K.5
Latus, L.J.6
Yakushiji, F.7
Ilondo, M.M.8
Shymko, R.M.9
-
6
-
-
0021924895
-
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
-
Ebina, Y. et al (1985) The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling. Cell, 40, 747-758.
-
(1985)
Cell
, vol.40
, pp. 747-758
-
-
Ebina, Y.1
-
7
-
-
0024845664
-
Substrate phosphorylation catalyzed by the insulin receptor
-
Flores-Riveros, J., Sibley, E., Kastelic, T. and Lane, D. (1989) Substrate phosphorylation catalyzed by the insulin receptor. J. Biol. Chem., 264, 21557-21572.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 21557-21572
-
-
Flores-Riveros, J.1
Sibley, E.2
Kastelic, T.3
Lane, D.4
-
8
-
-
0013239516
-
Diabetes mellitus
-
Stanbury, J.B., Wyngaarden, J.B., Fredrickson, D.S., Goldstein J.L. and Brown, M.S. (eds), McGraw-Hill
-
Foster, D.W. (1983) Diabetes mellitus. In Stanbury, J.B., Wyngaarden, J.B., Fredrickson, D.S., Goldstein J.L. and Brown, M.S. (eds), The Metabolic Basis of Inherited Diseases. 5th edn. McGraw-Hill, pp 99-117.
-
(1983)
The Metabolic Basis of Inherited Diseases. 5th Edn.
, pp. 99-117
-
-
Foster, D.W.1
-
9
-
-
84911299287
-
Insulin-like growth factors in mammalian development
-
Rosenblum, I.Y. and Heyner, S. (eds), CRC Press, Boca Raton, FL
-
Heyner, S., Mattson, B.A., Smith, R.M. and Rosenblum, I Y. (1989) Insulin-like growth factors in mammalian development. In Rosenblum, I.Y. and Heyner, S. (eds), Growth Factors in Mammalian Development. CRC Press, Boca Raton, FL, pp 9-112
-
(1989)
Growth Factors in Mammalian Development
, pp. 9-112
-
-
Heyner, S.1
Mattson, B.A.2
Smith, R.M.3
Rosenblum, I.Y.4
-
10
-
-
0029067312
-
Homozygosity for a null allele on the insulin receptor gene in a patient with leprechaunism
-
Hone, J., Accili, D., Psiachou, H , Alghband-Zadeh, J., Mitton, S., Wertheimer, E , Sinclair, L. and Taylor, S.I. (1995) Homozygosity for a null allele on the insulin receptor gene in a patient with leprechaunism. Human Mutat., 6, 17-22.
-
(1995)
Human Mutat.
, vol.6
, pp. 17-22
-
-
Hone, J.1
Accili, D.2
Psiachou, H.3
Alghband-Zadeh, J.4
Mitton, S.5
Wertheimer, E.6
Sinclair, L.7
Taylor, S.I.8
-
13
-
-
0027953703
-
Insulin action, diabetogenes and the cause of type II diabetes
-
Kahn, C.R. (1994) Insulin action, diabetogenes and the cause of type II diabetes. Diabetes, 43, 1066-1084.
-
(1994)
Diabetes
, vol.43
, pp. 1066-1084
-
-
Kahn, C.R.1
-
14
-
-
0029148426
-
Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4
-
Katz, E.B., Stenbit, A.E., Hatton, K., DePinho, R. and Charron, M.J. (1995) Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4. Nature, 377, 151-155.
-
(1995)
Nature
, vol.377
, pp. 151-155
-
-
Katz, E.B.1
Stenbit, A.E.2
Hatton, K.3
DePinho, R.4
Charron, M.J.5
-
15
-
-
0002169455
-
Glycogen
-
Bergmeyer, H.U. (ed.), Chimie Verlag GmbH, Weinheim, Germany
-
Keppler, D. and Decker, K. (1981) Glycogen. In Bergmeyer, H.U. (ed.), Methods of Enzymatic Analysis. Chimie Verlag GmbH, Weinheim, Germany, Vol VI, pp. 11-18.
-
(1981)
Methods of Enzymatic Analysis
, vol.6
, pp. 11-18
-
-
Keppler, D.1
Decker, K.2
-
16
-
-
0027301401
-
Homozygous nonsense mutation in the insulin receptor gene in infant with leprechaunism
-
Krook, A., Brueton, L. and O'Rahilly, S (1993) Homozygous nonsense mutation in the insulin receptor gene in infant with leprechaunism. Lancet, 342, 277-278.
-
(1993)
Lancet
, vol.342
, pp. 277-278
-
-
Krook, A.1
Brueton, L.2
O'Rahilly, S.3
-
17
-
-
0014949207
-
Cleavage of structural proteins during the assembly of head of bacteriophage T4
-
Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of head of bacteriophage T4. Nature, 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
18
-
-
0029085477
-
Interaction of p85 subunit of PI 3-kinase with insulin and IGF-1 receptors analyzed by using the two-hybrid system
-
Lamothe, B., Bucchini, D., Jami, J. and Joshi, R.L. (1995) Interaction of p85 subunit of PI 3-kinase with insulin and IGF-1 receptors analyzed by using the two-hybrid system. FEBS Lett., 373, 51-55
-
(1995)
FEBS Lett.
, vol.373
, pp. 51-55
-
-
Lamothe, B.1
Bucchini, D.2
Jami, J.3
Joshi, R.L.4
-
19
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (IGF1r)
-
Liu, J.R. Baker, J., Perkins, A.S., Roberston, E.J. and Efstratiadis, A. (1993) Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (IGF1r). Cell, 75, 59-72.
-
(1993)
Cell
, vol.75
, pp. 59-72
-
-
Liu, J.R.1
Baker, J.2
Perkins, A.S.3
Roberston, E.J.4
Efstratiadis, A.5
-
20
-
-
0024296027
-
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes
-
Mansour, S.L., Thomas, K.R. and Capecchi, M.R. (1988) Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature, 336, 348-352.
-
(1988)
Nature
, vol.336
, pp. 348-352
-
-
Mansour, S.L.1
Thomas, K.R.2
Capecchi, M.R.3
-
21
-
-
0020680990
-
A peroxidase-coupled method for the colorimetric determination of serum triglycerides
-
McGrown, M.W., Artiss, J.D., Strandbergh, D.R. and Zak, B. (1983) A peroxidase-coupled method for the colorimetric determination of serum triglycerides. Clin. Chem., 29, 538-542.
-
(1983)
Clin. Chem.
, vol.29
, pp. 538-542
-
-
McGrown, M.W.1
Artiss, J.D.2
Strandbergh, D.R.3
Zak, B.4
-
22
-
-
0028567063
-
Transgenic approaches to the pathogenesis of NIDDM
-
Moller, D E. (1994) Transgenic approaches to the pathogenesis of NIDDM. Diabetes. 43, 1394-1401.
-
(1994)
Diabetes
, vol.43
, pp. 1394-1401
-
-
Moller, D.E.1
-
23
-
-
0025945012
-
Insulin resistance - Mechanisms, syndromes, and implications
-
Moller, D.E and Flier, J.S. (1991) Insulin resistance - mechanisms, syndromes, and implications. New Engl. J. Med., 325, 938-948.
-
(1991)
New Engl. J. Med.
, vol.325
, pp. 938-948
-
-
Moller, D.E.1
Flier, J.S.2
-
24
-
-
0002282952
-
Is insulin a growth factor?
-
Le Roith, D. (ed.), CRC Press, Boca Raton, FL
-
Moses, A.C. and Tsuzaki, S (1991) Is insulin a growth factor? In Le Roith, D. (ed.), Insulin-like Growth Factors: Molecular and Cellular Aspects. CRC Press, Boca Raton, FL, pp. 245-270.
-
(1991)
Insulin-like Growth Factors: Molecular and Cellular Aspects
, pp. 245-270
-
-
Moses, A.C.1
Tsuzaki, S.2
-
25
-
-
0025051113
-
The insulin receptor a multifunctional protein
-
Olefsky, J.M. (1990) The insulin receptor a multifunctional protein. Diabetes, 39, 1009-1016.
-
(1990)
Diabetes
, vol.39
, pp. 1009-1016
-
-
Olefsky, J.M.1
-
26
-
-
0027495817
-
Leprechaunism and homozygous nonsense mutation in the insulin receptor gene
-
Psiachou, H., Mitton, S., Alaghband-Zadeh, J., Hone, J., Taylor, S.I , Sinclair, L. (1993) Leprechaunism and homozygous nonsense mutation in the insulin receptor gene. Lancet. 342, 924.
-
(1993)
Lancet
, vol.342
, pp. 924
-
-
Psiachou, H.1
Mitton, S.2
Alaghband-Zadeh, J.3
Hone, J.4
Taylor, S.I.5
Sinclair, L.6
-
28
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Sambrook, K., Fritsch, E F and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1989)
Molecular Cloning: A Laboratory Manual, 2nd Edn.
-
-
Sambrook, K.1
Fritsch, E.F.2
Maniatis, T.3
-
29
-
-
0024548162
-
Structure of the human insulin receptor gene and characterization of its promoter
-
Seino, S., Seino, M , Shigeo, N. and Bell, G.I. (1989) Structure of the human insulin receptor gene and characterization of its promoter. Proc. Natl Acad. Sci. USA, 86, 114-118.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 114-118
-
-
Seino, S.1
Seino, M.2
Shigeo, N.3
Bell, G.I.4
-
30
-
-
0024850427
-
Characterization of the mouse insulin receptor gene promoter
-
Sibley, E., Kastelic, T., Kelly, T.J. and Lane, M.D. (1989) Characterization of the mouse insulin receptor gene promoter. Proc. Natl Acad. Sci. USA, 86, 9732-9736.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 9732-9736
-
-
Sibley, E.1
Kastelic, T.2
Kelly, T.J.3
Lane, M.D.4
-
31
-
-
0029083111
-
Control of adipocyte differentiation
-
Smas, C.M. and Sul, H.S. (1995) Control of adipocyte differentiation. Biochem. J., 309, 697-710.
-
(1995)
Biochem. J.
, vol.309
, pp. 697-710
-
-
Smas, C.M.1
Sul, H.S.2
-
32
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
Tamemoto, H. et al. (1994) Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature, 372, 182-186.
-
(1994)
Nature
, vol.372
, pp. 182-186
-
-
Tamemoto, H.1
-
33
-
-
0026656320
-
Lessons from patients with mutations in the insulin-receptor gene
-
Taylor, S.I. (1992) Lessons from patients with mutations in the insulin-receptor gene. Diabetes, 41, 1473-1490.
-
(1992)
Diabetes
, vol.41
, pp. 1473-1490
-
-
Taylor, S.I.1
-
34
-
-
4243268721
-
Structure and function of insulin receptors
-
Le Roith, D. (ed.), CRC Press, Boca Raton, FL
-
Taylor, S.I., Najjar, S., Cama, A. and Accili, D. (1991) Structure and function of insulin receptors. In Le Roith, D. (ed.), Insulin-like Growth Factors: Molecular and Cellular Aspects. CRC Press, Boca Raton, FL. pp. 221-244.
-
(1991)
Insulin-like Growth Factors: Molecular and Cellular Aspects
, pp. 221-244
-
-
Taylor, S.I.1
Najjar, S.2
Cama, A.3
Accili, D.4
-
35
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedures and some applications
-
Towbin, H., Staehelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedures and some applications. Proc. Natl Acad. Sci. USA, 76, 4350-4354.
-
(1979)
Proc. Natl Acad. Sci. USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
36
-
-
0014481680
-
Determination of blood glucose using 4-amino phenazone as oxygen acceptor
-
Trinder, P. (1969) Determination of blood glucose using 4-amino phenazone as oxygen acceptor. Ann. Clin. Biochem , 22, 246.
-
(1969)
Ann. Clin. Biochem
, vol.22
, pp. 246
-
-
Trinder, P.1
-
37
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich, A. and Schlessinger, J. (1990) Signal transduction by receptors with tyrosine kinase activity. Cell, 61, 203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
38
-
-
0021985413
-
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
-
Ullrich, A. et al. (1985) Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature, 313, 756-761.
-
(1985)
Nature
, vol.313
, pp. 756-761
-
-
Ullrich, A.1
-
39
-
-
0001828896
-
The insulin-like growth factor I receptor: Molecular biology, heterogeneity, and regulation
-
Le Roith, D. (ed.), CRC Press, Boca Raton. FL
-
Werner, H., Woloschlak, M , Stannard, B., Shen-Orr, Z., Roberts, C.T., Jr and Le Roith, D. (1991) The insulin-like growth factor I receptor: molecular biology, heterogeneity, and regulation. In Le Roith, D. (ed.), Insulin-like Growth Factors: Molecular and Cellular Aspects. CRC Press, Boca Raton. FL, pp. 15-47.
-
(1991)
Insulin-like Growth Factors: Molecular and Cellular Aspects
, pp. 15-47
-
-
Werner, H.1
Woloschlak, M.2
Stannard, B.3
Shen-Orr, Z.4
Roberts Jr., C.T.5
Le Roith, D.6
-
40
-
-
0027179476
-
Homozygous deletion of the human insulin receptor gene results in leprechaunism
-
Wertheimer, E., Lu, S P., Backeljauw, P.F., Davenport, M.L. and Taylor, S.I. (1993) Homozygous deletion of the human insulin receptor gene results in leprechaunism. Nature Genet., 5, 71-73.
-
(1993)
Nature Genet.
, vol.5
, pp. 71-73
-
-
Wertheimer, E.1
Lu, S.P.2
Backeljauw, P.F.3
Davenport, M.L.4
Taylor, S.I.5
-
41
-
-
0028085078
-
The insulin signaling system
-
White, M.F. and Kahn, C.R. (1994) The insulin signaling system. J. Biol. Chem., 269, 1-4.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1-4
-
-
White, M.F.1
Kahn, C.R.2
|