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Volumn 3, Issue 1, 2010, Pages 23-34

Redox regulation in cancer: A double-edged sword with therapeutic potential

Author keywords

Antioxidants; BRCA1; Cancer stem cells; Detoxification enzymes; NF B; NRF2; Phase II; ROS

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 INDOLEMETHANOL; 3,3' DIINDOLYLMETHANE; BRCA1 PROTEIN; CAPSAICIN; CARDAMOM EXTRACT; CINNAMON EXTRACT; CISPLATIN; CLOVE EXTRACT; CURCUMIN; CYTOTOXIC AGENT; DAIDZEIN; ESTROGEN RECEPTOR; GARLIC EXTRACT; GENISTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; TRASTUZUMAB; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 77953384917     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.4161/oxim.3.1.10095     Document Type: Article
Times cited : (393)

References (148)
  • 1
    • 38049090214 scopus 로고    scopus 로고
    • DNA replication stress, genome instability and aging
    • Burhans WC, Weinberger M. DNA replication stress, genome instability and aging. Nucleic Acids Res 2007; 35:7545-56.
    • (2007) Nucleic Acids Res , vol.35 , pp. 7545-7556
    • Burhans, W.C.1    Weinberger, M.2
  • 3
    • 61449125226 scopus 로고    scopus 로고
    • Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer
    • Khansari N, Shakiba Y, Mahmoudi M. Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer. Recent Pat Inflamm Allergy Drug Discov 2009; 3:73-80.
    • (2009) Recent Pat Inflamm Allergy Drug Discov , vol.3 , pp. 73-80
    • Khansari, N.1    Shakiba, Y.2    Mahmoudi, M.3
  • 5
    • 39149106144 scopus 로고    scopus 로고
    • Mitochondrial metabolism, redox signaling and fusion: A mitochondria- ROS-HIF-1alpha-KV1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer
    • Archer SL, Gomberg-Maitland M, Maitland ML, Rich S, Garcia JG, Weir EK. Mitochondrial metabolism, redox signaling and fusion: a mitochondria- ROS-HIF-1alpha-KV1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am J Physiol Heart Circ Physiol 2008; 294:570-8.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294 , pp. 570-578
    • Archer, S.L.1    Gomberg-Maitland, M.2    Maitland, M.L.3    Rich, S.4    Garcia, J.G.5    Weir, E.K.6
  • 6
    • 27844486110 scopus 로고    scopus 로고
    • Modulation of xenobiotic metabolising enzymes by anticarcinogens- focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis
    • Pool-Zobel B, Veeriah S, Bohmer FD. Modulation of xenobiotic metabolising enzymes by anticarcinogens- focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis. Mutat Res 2005; 591:74-92.
    • (2005) Mutat Res , vol.591 , pp. 74-92
    • Pool-Zobel, B.1    Veeriah, S.2    Bohmer, F.D.3
  • 7
    • 61449135219 scopus 로고    scopus 로고
    • Gamma-tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice
    • Barve A, Khor TO, Nair S, Reuhl K, Suh N, Reddy B, et al. Gamma-tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice. Int J Cancer 2009; 124:1693-9.
    • (2009) Int J Cancer , vol.124 , pp. 1693-1699
    • Barve, A.1    Khor, T.O.2    Nair, S.3    Reuhl, K.4    Suh, N.5    Reddy, B.6
  • 8
    • 34548794015 scopus 로고    scopus 로고
    • Chemoprevention of rat mammary carcinogenesis by black tea polyphenols: Modulation of xenobioticmetabolizing enzymes, oxidative stress, cell proliferation, apoptosis and angiogenesis
    • Kumaraguruparan R, Seshagiri PB, Hara Y, Nagini S. Chemoprevention of rat mammary carcinogenesis by black tea polyphenols: modulation of xenobioticmetabolizing enzymes, oxidative stress, cell proliferation, apoptosis and angiogenesis. Mol Carcinog 2007; 46:797-806.
    • (2007) Mol Carcinog , vol.46 , pp. 797-806
    • Kumaraguruparan, R.1    Seshagiri, P.B.2    Hara, Y.3    Nagini, S.4
  • 9
    • 77953384426 scopus 로고    scopus 로고
    • Induction of the phase ii detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of schisandra chinensis through nuclear accumulation of Nrf2
    • Lee SB, Kim CY, Lee HJ, Yun JH, Nho CW. Induction of the Phase II Detoxification Enzyme NQO1 in Hepatocarcinoma Cells by Lignans from the Fruit of Schisandra chinensis through Nuclear Accumulation of Nrf2. Planta Med 2009; 18:18.
    • (2009) Planta Med , vol.18 , pp. 18
    • Lee, S.B.1    Kim, C.Y.2    Lee, H.J.3    Yun, J.H.4    Nho, C.W.5
  • 10
    • 33947680664 scopus 로고    scopus 로고
    • Natural dietary anti-cancer chemopreventive compounds: Redox-mediated differential signaling mechanisms in cytoprotection of normal cells versus cytotoxicity in tumor cells
    • Nair S, Li W, Kong AN. Natural dietary anti-cancer chemopreventive compounds: redox-mediated differential signaling mechanisms in cytoprotection of normal cells versus cytotoxicity in tumor cells. Acta Pharmacol Sin 2007; 28:459-72.
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 459-472
    • Nair, S.1    Li, W.2    Kong, A.N.3
  • 11
    • 46749150470 scopus 로고    scopus 로고
    • Organoselenium compounds in cancer chemoprevention
    • Naithani R. Organoselenium compounds in cancer chemoprevention. Mini Rev Med Chem 2008; 8:657-68.
    • (2008) Mini Rev Med Chem , vol.8 , pp. 657-668
    • Naithani, R.1
  • 12
    • 67650735222 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular disease: Novel tools give (free) radical insight
    • Fearon IM, Faux SP. Oxidative stress and cardiovascular disease: novel tools give (free) radical insight. J Mol Cell Cardiol 2009; 47:372-81.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 372-381
    • Fearon, I.M.1    Faux, S.P.2
  • 13
    • 77953376153 scopus 로고    scopus 로고
    • Tipping the redox balance of oxidative stress in fibrogenic pathways in chronic kidney disease
    • Okamura DM, Himmelfarb J. Tipping the redox balance of oxidative stress in fibrogenic pathways in chronic kidney disease. Pediatr Nephrol 2009; 7:7.
    • (2009) Pediatr Nephrol , vol.7 , pp. 7
    • Okamura, D.M.1    Himmelfarb, J.2
  • 14
    • 67649678412 scopus 로고    scopus 로고
    • Oxidative stress in diabetes and Alzheimer's disease
    • Reddy VP, Zhu X, Perry G, Smith MA. Oxidative stress in diabetes and Alzheimer's disease. J Alzheimers Dis 2009; 16:763-74.
    • (2009) J Alzheimers Dis , vol.16 , pp. 763-774
    • Reddy, V.P.1    Zhu, X.2    Perry, G.3    Smith, M.A.4
  • 15
    • 61349091797 scopus 로고    scopus 로고
    • Oxidative stress in developmental origins of disease: Teratogenesis, neurodevelopmental deficits and cancer
    • Wells PG, McCallum GP, Chen CS, Henderson JT, Lee CJ, Perstin J, et al. Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits and cancer. Toxicol Sci 2009; 108:4-18.
    • (2009) Toxicol Sci , vol.108 , pp. 4-18
    • Wells, P.G.1    McCallum, G.P.2    Chen, C.S.3    Henderson, J.T.4    Lee, C.J.5    Perstin, J.6
  • 16
    • 67649968443 scopus 로고    scopus 로고
    • Oxidative stress and alcoholic liver disease
    • Wu D, Cederbaum AI. Oxidative stress and alcoholic liver disease. Semin Liver Dis 2009; 29:141-54.
    • (2009) Semin Liver Dis , vol.29 , pp. 141-154
    • Wu, D.1    Cederbaum, A.I.2
  • 18
  • 19
    • 33748344714 scopus 로고    scopus 로고
    • Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: Role of lipid peroxidation, DNA damage and repair
    • Bartsch H, Nair J. Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage and repair. Langenbecks Arch Surg 2006; 391:499-510.
    • (2006) Langenbecks Arch Surg , vol.391 , pp. 499-510
    • Bartsch, H.1    Nair, J.2
  • 20
    • 3242886115 scopus 로고    scopus 로고
    • DNA damage responses to oxidative stress
    • Barzilai A, Yamamoto K. DNA damage responses to oxidative stress. DNA Repair 2004; 3:1109-15.
    • (2004) DNA Repair , vol.3 , pp. 1109-1115
    • Barzilai, A.1    Yamamoto, K.2
  • 21
    • 33750915424 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress, DNA damage, and heart failure
    • DOI 10.1089/ars.2006.8.1737
    • Tsutsui H, Ide T, Kinugawa S. Mitochondrial oxidative stress, DNA damage and heart failure. Antioxid Redox Signal 2006; 8:1737-44. (Pubitemid 44726346)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.9-10 , pp. 1737-1744
    • Tsutsui, H.1    Ide, T.2    Kinugawa, S.3
  • 22
    • 0038799736 scopus 로고    scopus 로고
    • Oxidative DNA damage: Mechanisms, mutation, and disease
    • DOI 10.1096/fj.02-0752rev
    • Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation and disease. Faseb J 2003; 17:1195-214. (Pubitemid 36775767)
    • (2003) FASEB Journal , vol.17 , Issue.10 , pp. 1195-1214
    • Cooke, M.S.1    Evans, M.D.2    Dizdaroglu, M.3    Lunec, J.4
  • 23
    • 0034011261 scopus 로고    scopus 로고
    • Oxyradicals and DNA damage
    • Marnett LJ. Oxyradicals and DNA damage. Carcinogenesis 2000; 21:361-70.
    • (2000) Carcinogenesis , vol.21 , pp. 361-370
    • Marnett, L.J.1
  • 25
    • 0036494147 scopus 로고    scopus 로고
    • Defective repair of 8-hydroxyguanine in mitochondria of MCF-7 and MDA-MB-468 human breast cancer cell lines
    • Mambo E, Nyaga SG, Bohr VA, Evans MK. Defective repair of 8-hydroxyguanine in mitochondria of MCF-7 and MDA-MB-468 human breast cancer cell lines. Cancer Res 2002; 62:1349-55.
    • (2002) Cancer Res , vol.62 , pp. 1349-1355
    • Mambo, E.1    Nyaga, S.G.2    Bohr, V.A.3    Evans, M.K.4
  • 27
    • 0037304032 scopus 로고    scopus 로고
    • Cancer and phase II drug-metabolizing enzymes
    • Sheweita SA, Tilmisany AK. Cancer and phase II drug-metabolizing enzymes. Curr Drug Metab 2003; 4:45-58.
    • (2003) Curr Drug Metab , vol.4 , pp. 45-58
    • Sheweita, S.A.1    Tilmisany, A.K.2
  • 28
    • 4544250814 scopus 로고    scopus 로고
    • Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells
    • Vaquero EC, Edderkaoui M, Pandol SJ, Gukovsky I, Gukovskaya AS. Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. J Biol Chem 2004; 279:34643-54.8.
    • (2004) J Biol Chem , vol.279 , pp. 34643-35548
    • Vaquero, E.C.1    Edderkaoui, M.2    Pandol, S.J.3    Gukovsky, I.4    Gukovskaya, A.S.5
  • 29
    • 65649120706 scopus 로고    scopus 로고
    • Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29
    • Vizan P, Alcarraz-Vizan G, Diaz-Moralli S, Solovjeva ON, Frederiks WM, Cascante M. Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29. Int J Cancer 2009; 124:2789-96.
    • (2009) Int J Cancer , vol.124 , pp. 2789-2796
    • Vizan, P.1    Alcarraz-Vizan, G.2    Diaz-Moralli, S.3    Solovjeva, O.N.4    Frederiks, W.M.5    Cascante, M.6
  • 31
    • 63049120687 scopus 로고    scopus 로고
    • Selenite induces redox-dependent Bax activation and apoptosis in colorectal cancer cells
    • Huang F, Nie C, Yang Y, Yue W, Ren Y, Shang Y, et al. Selenite induces redox-dependent Bax activation and apoptosis in colorectal cancer cells. Free Radic Biol Med 2009; 46:1186-96.
    • (2009) Free Radic Biol Med , vol.46 , pp. 1186-1196
    • Huang, F.1    Nie, C.2    Yang, Y.3    Yue, W.4    Ren, Y.5    Shang, Y.6
  • 32
    • 26944444679 scopus 로고    scopus 로고
    • BRCA1 in hormonal carcinogenesis: Basic and clinical research
    • Rosen EM, Fan S, Isaacs C. BRCA1 in hormonal carcinogenesis: basic and clinical research. Endocr Relat Cancer 2005; 12:533-48.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 533-548
    • Rosen, E.M.1    Fan, S.2    Isaacs, C.3
  • 34
    • 7444271583 scopus 로고    scopus 로고
    • BRCA1 induces antioxidant gene expression and resistance to oxidative stress
    • Bae I, Fan S, Meng Q, Rih JK, Kim HJ, Kang HJ, et al. BRCA1 induces antioxidant gene expression and resistance to oxidative stress. Cancer Res 2004; 64:7893-909.
    • (2004) Cancer Res , vol.64 , pp. 7893-7909
    • Bae, I.1    Fan, S.2    Meng, Q.3    Rih, J.K.4    Kim, H.J.5    Kang, H.J.6
  • 35
    • 34547797471 scopus 로고    scopus 로고
    • Absence of full-length Brca1 sensitizes mice to oxidative stress and carcinogen-induced tumorigenesis in the esophagus and forestomach
    • Cao L, Xu X, Cao LL, Wang RH, Coumoul X, Kim SS, et al. Absence of full-length Brca1 sensitizes mice to oxidative stress and carcinogen-induced tumorigenesis in the esophagus and forestomach. Carcinogenesis 2007; 28:1401-7.
    • (2007) Carcinogenesis , vol.28 , pp. 1401-1407
    • Cao, L.1    Xu, X.2    Cao, L.L.3    Wang, R.H.4    Coumoul, X.5    Kim, S.S.6
  • 36
    • 0034946638 scopus 로고    scopus 로고
    • Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
    • Xu X, Qiao W, Linke SP, Cao L, Li WM, Furth PA, et al. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nat Genet 2001; 28:266-71.
    • (2001) Nat Genet , vol.28 , pp. 266-271
    • Xu, X.1    Qiao, W.2    Linke, S.P.3    Cao, L.4    Li, W.M.5    Furth, P.A.6
  • 37
    • 67349272025 scopus 로고    scopus 로고
    • BRCA1 downregulates cellular levels of reactive oxygen species
    • Saha T, Rih JK, Rosen EM. BRCA1 downregulates cellular levels of reactive oxygen species. FEBS Lett 2009; 583:1535-43.
    • (2009) FEBS Lett , vol.583 , pp. 1535-1543
    • Saha, T.1    Rih, J.K.2    Rosen, E.M.3
  • 38
    • 33744962596 scopus 로고    scopus 로고
    • BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells
    • Kang HJ, Kim HJ, Kim SK, Barouki R, Cho CH, Khanna KK, et al. BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells. J Biol Chem 2006; 281:14654-62.
    • (2006) J Biol Chem , vol.281 , pp. 14654-14662
    • Kang, H.J.1    Kim, H.J.2    Kim, S.K.3    Barouki, R.4    Cho, C.H.5    Khanna, K.K.6
  • 39
    • 70349988879 scopus 로고    scopus 로고
    • APE1/Ref-1: Versatility in progress
    • Jeon BH, Irani K. APE1/Ref-1: Versatility in Progress. Antioxid Redox Signal 2008; 20:20.
    • (2008) Antioxid Redox Signal , vol.20 , pp. 20
    • Jeon, B.H.1    Irani, K.2
  • 40
    • 77953463329 scopus 로고    scopus 로고
    • Essential role of DNA base excision repair on survival in an acidic tumor microenvironment
    • Seo Y, Kinsella TJ. Essential Role of DNA Base Excision Repair on Survival in an Acidic Tumor Microenvironment. Cancer Res 2009; 1:1.
    • (2009) Cancer Res , vol.1 , pp. 1
    • Seo, Y.1    Kinsella, T.J.2
  • 41
    • 48949116282 scopus 로고    scopus 로고
    • Estrogen enhanced cell-cell signalling in breast cancer cells exposed to targeted irradiation
    • Shao C, Folkard M, Held KD, Prise KM. Estrogen enhanced cell-cell signalling in breast cancer cells exposed to targeted irradiation. BMC Cancer 2008; 8:184.
    • (2008) BMC Cancer , vol.8 , pp. 184
    • Shao, C.1    Folkard, M.2    Held, K.D.3    Prise, K.M.4
  • 43
    • 67449105000 scopus 로고    scopus 로고
    • Estrogen receptor {alpha} enhances the rate of oxidative DNA damage by targeting an equine estrogen catechol metabolite to the nucleus
    • Wang Z, Wijewickrama GT, Peng KW, Dietz BM, Yuan L, van Breemen RB, et al. Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus. J Biol Chem 2009; 284:8633-42.
    • (2009) J Biol Chem , vol.284 , pp. 8633-8642
    • Wang, Z.1    Wijewickrama, G.T.2    Peng, K.W.3    Dietz, B.M.4    Yuan, L.5    Van Breemen, R.B.6
  • 44
    • 77953413415 scopus 로고    scopus 로고
    • Reactive oxygen species induce phosphorylation of serine 118 and 167 on estrogen receptor alpha
    • Weitsman GE, Weebadda W, Ung K, Murphy LC. Reactive oxygen species induce phosphorylation of serine 118 and 167 on estrogen receptor alpha. Breast Cancer Res Treat 2008; 21:21.
    • (2008) Breast Cancer Res Treat , vol.21 , pp. 21
    • Weitsman, G.E.1    Weebadda, W.2    Ung, K.3    Murphy, L.C.4
  • 45
    • 33645242394 scopus 로고    scopus 로고
    • Estradiol and its metabolites 4-hydroxyestradiol and 2-hydroxyestradiol induce mutations in human breast epithelial cells
    • Fernandez SV, Russo IH, Russo J. Estradiol and its metabolites 4-hydroxyestradiol and 2-hydroxyestradiol induce mutations in human breast epithelial cells. Int J Cancer 2006; 118:1862-8.
    • (2006) Int J Cancer , vol.118 , pp. 1862-1868
    • Fernandez, S.V.1    Russo, I.H.2    Russo, J.3
  • 46
    • 0034667480 scopus 로고    scopus 로고
    • Alcohol stimulates estrogen receptor signaling in human breast cancer cell lines
    • Fan S, Meng Q, Gao B, Grossman J, Yadegari M, Goldberg ID, et al. Alcohol stimulates estrogen receptor signaling in human breast cancer cell lines. Cancer Res 2000; 60:5635-9.
    • (2000) Cancer Res , vol.60 , pp. 5635-5639
    • Fan, S.1    Meng, Q.2    Gao, B.3    Grossman, J.4    Yadegari, M.5    Goldberg, I.D.6
  • 47
    • 2942726209 scopus 로고    scopus 로고
    • BRCA1 inhibits membrane estrogen and growth factor receptor signaling to cell proliferation in breast cancer
    • Razandi M, Pedram A, Rosen EM, Levin ER. BRCA1 inhibits membrane estrogen and growth factor receptor signaling to cell proliferation in breast cancer. Mol Cell Biol 2004; 24:5900-13.
    • (2004) Mol Cell Biol , vol.24 , pp. 5900-5913
    • Razandi, M.1    Pedram, A.2    Rosen, E.M.3    Levin, E.R.4
  • 48
    • 33746847720 scopus 로고    scopus 로고
    • Catechol estrogen quinones as initiators of breast and other human cancers: Implications for biomarkers of susceptibility and cancer prevention
    • Cavalieri E, Chakravarti D, Guttenplan J, Hart E, Ingle J, Jankowiak R, et al. Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention. Biochim Biophys Acta 2006; 1766:63-78.
    • (2006) Biochim Biophys Acta , vol.1766 , pp. 63-78
    • Cavalieri, E.1    Chakravarti, D.2    Guttenplan, J.3    Hart, E.4    Ingle, J.5    Jankowiak, R.6
  • 49
    • 64549149708 scopus 로고    scopus 로고
    • Src supports UDP-glucuronosyltransferase- 2B7 detoxification of catechol estrogens associated with breast cancer
    • Mitra PS, Basu NK, Owens IS. Src supports UDP-glucuronosyltransferase- 2B7 detoxification of catechol estrogens associated with breast cancer. Biochem Biophys Res Commun 2009; 382:651-6.
    • (2009) Biochem Biophys Res Commun , vol.382 , pp. 651-656
    • Mitra, P.S.1    Basu, N.K.2    Owens, I.S.3
  • 50
    • 0031842235 scopus 로고    scopus 로고
    • Impact of oestradiol and progesterone on antioxidant activity in normal human breast epithelial cells in culture
    • Dabrosin C, Hammar M, Ollinger K. Impact of oestradiol and progesterone on antioxidant activity in normal human breast epithelial cells in culture. Free Radic Res 1998; 28:241-9.
    • (1998) Free Radic Res , vol.28 , pp. 241-249
    • Dabrosin, C.1    Hammar, M.2    Ollinger, K.3
  • 51
    • 1642422891 scopus 로고    scopus 로고
    • Estrogen receptormediated regulation of oxidative stress and DNA damage in breast cancer
    • Mobley JA, Brueggemeier RW. Estrogen receptormediated regulation of oxidative stress and DNA damage in breast cancer. Carcinogenesis 2004; 25:3-9.
    • (2004) Carcinogenesis , vol.25 , pp. 3-9
    • Mobley, J.A.1    Brueggemeier, R.W.2
  • 52
    • 77953450403 scopus 로고    scopus 로고
    • Thioredoxin and thioredoxin reductase influence estrogen receptor {alpha} mediated gene expression in human breast cancer cells
    • Rao A, Ziegler Y, McLeod I, Yates J, Nardulli A. Thioredoxin and thioredoxin reductase influence estrogen receptor {alpha} mediated gene expression in human breast cancer cells. J Mol Endocrinol 2009; 20:20.
    • (2009) J Mol Endocrinol , vol.20 , pp. 20
    • Rao, A.1    Ziegler, Y.2    McLeod, I.3    Yates, J.4    Nardulli, A.5
  • 54
    • 54549097590 scopus 로고    scopus 로고
    • Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers
    • Yau C, Benz CC. Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers. Breast Cancer Res 2008; 10:17.
    • (2008) Breast Cancer Res , vol.10 , pp. 17
    • Yau, C.1    Benz, C.C.2
  • 56
    • 67749147128 scopus 로고    scopus 로고
    • Mechanism of BRCA1-mediated inhibition of progesterone receptor transcriptional activity
    • Katiyar P, Ma Y, Riegel A, Fan S, Rosen EM. Mechanism of BRCA1-mediated inhibition of progesterone receptor transcriptional activity. Mol Endocrinol 2009; 23:1135-46.
    • (2009) Mol Endocrinol , vol.23 , pp. 1135-1146
    • Katiyar, P.1    Ma, Y.2    Riegel, A.3    Fan, S.4    Rosen, E.M.5
  • 57
    • 64749093574 scopus 로고    scopus 로고
    • Association of reactive oxygen species levels and radioresistance in cancer stem cells
    • Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN, et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009; 458:780-3.
    • (2009) Nature , vol.458 , pp. 780-783
    • Diehn, M.1    Cho, R.W.2    Lobo, N.A.3    Kalisky, T.4    Dorie, M.J.5    Kulp, A.N.6
  • 58
    • 35548936968 scopus 로고    scopus 로고
    • A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
    • Jang YY, Sharkis SJ. A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 2007; 110:3056-63.
    • (2007) Blood , vol.110 , pp. 3056-3063
    • Jang, Y.Y.1    Sharkis, S.J.2
  • 59
    • 51349120502 scopus 로고    scopus 로고
    • Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells
    • Naka K, Muraguchi T, Hoshii T, Hirao A. Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells. Antioxid Redox Signal 2008; 10:1883-94.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1883-1894
    • Naka, K.1    Muraguchi, T.2    Hoshii, T.3    Hirao, A.4
  • 60
    • 64549108961 scopus 로고    scopus 로고
    • Redox regulation and its emerging roles in stem cells and stem-like cancer cells
    • Ogasawara MA, Zhang H. Redox Regulation and its Emerging Roles in Stem Cells and Stem-Like Cancer Cells. Antioxid Redox Signal 2008; 11:11.
    • (2008) Antioxid Redox Signal , vol.11 , pp. 11
    • Ogasawara, M.A.1    Zhang, H.2
  • 61
    • 66749098316 scopus 로고    scopus 로고
    • Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer
    • Blum R, Gupta R, Burger PE, Ontiveros CS, Salm SN, Xiong X, et al. Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer. PLoS One 2009; 4:5722.
    • (2009) PLoS One , vol.4 , pp. 5722
    • Blum, R.1    Gupta, R.2    Burger, P.E.3    Ontiveros, C.S.4    Salm, S.N.5    Xiong, X.6
  • 62
    • 45549085634 scopus 로고    scopus 로고
    • Human colon cancer stem cells: A new paradigm in gastrointestinal oncology
    • Boman BM, Huang E. Human colon cancer stem cells: a new paradigm in gastrointestinal oncology. J Clin Oncol 2008; 26:2828-38.
    • (2008) J Clin Oncol , vol.26 , pp. 2828-2838
    • Boman, B.M.1    Huang, E.2
  • 63
    • 66449115036 scopus 로고    scopus 로고
    • PTEN, stem cells and cancer stem cells
    • Hill R, Wu H. PTEN, stem cells and cancer stem cells. J Biol Chem 2009; 284:11755-9.
    • (2009) J Biol Chem , vol.284 , pp. 11755-11759
    • Hill, R.1    Wu, H.2
  • 64
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One 2008; 3:2888.
    • (2008) PLoS One , vol.3 , pp. 2888
    • Morel, A.P.1    Lievre, M.2    Thomas, C.3    Hinkal, G.4    Ansieau, S.5    Puisieux, A.6
  • 65
    • 40649116943 scopus 로고    scopus 로고
    • Progenitor/stem cells give rise to liver cancer due to aberrant TGFbeta and IL-6 signaling
    • Tang Y, Kitisin K, Jogunoori W, Li C, Deng CX, Mueller SC, et al. Progenitor/stem cells give rise to liver cancer due to aberrant TGFbeta and IL-6 signaling. Proc Natl Acad Sci USA 2008; 105:2445-50.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2445-2450
    • Tang, Y.1    Kitisin, K.2    Jogunoori, W.3    Li, C.4    Deng, C.X.5    Mueller, S.C.6
  • 66
    • 34547660196 scopus 로고    scopus 로고
    • FoxO transcription factors and stem cell homeostasis: Insights from the hematopoietic system
    • Tothova Z, Gilliland DG. FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system. Cell Stem Cell 2007; 1:140-52.
    • (2007) Cell Stem Cell , vol.1 , pp. 140-152
    • Tothova, Z.1    Gilliland, D.G.2
  • 67
    • 61349187121 scopus 로고    scopus 로고
    • A novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancerinitiating cell
    • Ito K, Bernardi R, Pandolfi PP. A novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancerinitiating cell. Curr Opin Genet Dev 2009; 19:51-9.
    • (2009) Curr Opin Genet Dev , vol.19 , pp. 51-59
    • Ito, K.1    Bernardi, R.2    Pandolfi, P.P.3
  • 68
    • 60849083805 scopus 로고    scopus 로고
    • A radical bailout strategy for cancer stem cells
    • Tothova Z, Gilliland DG. A radical bailout strategy for cancer stem cells. Cell Stem Cell 2009; 4:196-7.
    • (2009) Cell Stem Cell , vol.4 , pp. 196-197
    • Tothova, Z.1    Gilliland, D.G.2
  • 69
    • 33751178410 scopus 로고    scopus 로고
    • The thioredoxin system in cancer
    • Arner ES, Holmgren A. The thioredoxin system in cancer. Semin Cancer Biol 2006; 16:420-6.
    • (2006) Semin Cancer Biol , vol.16 , pp. 420-426
    • Arner, E.S.1    Holmgren, A.2
  • 70
    • 38149090141 scopus 로고    scopus 로고
    • Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer
    • Noike T, Miwa S, Soeda J, Kobayashi A, Miyagawa S. Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer. Hum Pathol 2008; 39:201-8.
    • (2008) Hum Pathol , vol.39 , pp. 201-208
    • Noike, T.1    Miwa, S.2    Soeda, J.3    Kobayashi, A.4    Miyagawa, S.5
  • 72
    • 0030044628 scopus 로고    scopus 로고
    • Enhancement of chemosensitivity by tyrphostin AG825 in high-p185(neu) expressing non-small cell lung cancer cells
    • Tsai CM, Levitzki A, Wu LH, Chang KT, Cheng CC, Gazit A, et al. Enhancement of chemosensitivity by tyrphostin AG825 in high-p185(neu) expressing non-small cell lung cancer cells. Cancer Res 1996; 56:1068-74.
    • (1996) Cancer Res , vol.56 , pp. 1068-1074
    • Tsai, C.M.1    Levitzki, A.2    Wu, L.H.3    Chang, K.T.4    Cheng, C.C.5    Gazit, A.6
  • 73
    • 0032510679 scopus 로고    scopus 로고
    • Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases
    • Nagane M, Levitzki A, Gazit A, Cavenee WK, Huang HJ. Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases. Proc Natl Acad Sci USA 1998; 95:5724-9.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5724-5729
    • Nagane, M.1    Levitzki, A.2    Gazit, A.3    Cavenee, W.K.4    Huang, H.J.5
  • 74
    • 0034473393 scopus 로고    scopus 로고
    • Trastuzumab and chemotherapeutics: Drug interactions and synergies
    • Pegram MD, Lopez A, Konecny G, Slamon DJ. Trastuzumab and chemotherapeutics: drug interactions and synergies. Semin Oncol 2000; 27:21-5.
    • (2000) Semin Oncol , vol.27 , pp. 21-25
    • Pegram, M.D.1    Lopez, A.2    Konecny, G.3    Slamon, D.J.4
  • 75
    • 68049137923 scopus 로고    scopus 로고
    • Low concentrations of diindolylmethane, a metabolite of indole-3-carbinol, protect against oxidative stress in a BRCA1-dependent manner
    • Fan S, Meng Q, Saha T, Sarkar FH, Rosen EM. Low concentrations of diindolylmethane, a metabolite of indole-3-carbinol, protect against oxidative stress in a BRCA1-dependent manner. Cancer Res 2009; 69:6083-91.
    • (2009) Cancer Res , vol.69 , pp. 6083-6091
    • Fan, S.1    Meng, Q.2    Saha, T.3    Sarkar, F.H.4    Rosen, E.M.5
  • 76
    • 32544442522 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells
    • Fan S, Meng Q, Auborn K, Carter T, Rosen EM. BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells. Br J Cancer 2006; 94:407-26.
    • (2006) Br J Cancer , vol.94 , pp. 407-426
    • Fan, S.1    Meng, Q.2    Auborn, K.3    Carter, T.4    Rosen, E.M.5
  • 77
    • 48749117943 scopus 로고    scopus 로고
    • Multi-targeted therapy of cancer by genistein
    • Banerjee S, Li Y, Wang Z, Sarkar FH. Multi-targeted therapy of cancer by genistein. Cancer Lett 2008; 269:226-42.
    • (2008) Cancer Lett , vol.269 , pp. 226-242
    • Banerjee, S.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 79
    • 53149143919 scopus 로고    scopus 로고
    • The major chemical-detoxifying system of UDP-glucuronosyltransferases requires regulated phosphorylation supported by protein kinase C
    • Basu NK, Kole L, Basu M, Chakraborty K, Mitra PS, Owens IS. The major chemical-detoxifying system of UDP-glucuronosyltransferases requires regulated phosphorylation supported by protein kinase C. J Biol Chem 2008; 283:23048-61.
    • (2008) J Biol Chem , vol.283 , pp. 23048-23061
    • Basu, N.K.1    Kole, L.2    Basu, M.3    Chakraborty, K.4    Mitra, P.S.5    Owens, I.S.6
  • 81
    • 34250851354 scopus 로고    scopus 로고
    • Targeted inhibition of glucuronidation markedly improves drug efficacy in mice-a model
    • Basu NK, Kole L, Basu M, McDonagh AF, Owens IS. Targeted inhibition of glucuronidation markedly improves drug efficacy in mice-a model. Biochem Biophys Res Commun 2007; 360:7-13.
    • (2007) Biochem Biophys Res Commun , vol.360 , pp. 7-13
    • Basu, N.K.1    Kole, L.2    Basu, M.3    McDonagh, A.F.4    Owens, I.S.5
  • 82
    • 58249093172 scopus 로고    scopus 로고
    • Inhibition of lipid peroxidation and enhancement of GST activity by cardamom and cinnamon during chemically induced colon carcinogenesis in Swiss albino mice
    • Bhattacharjee S, Rana T, Sengupta A. Inhibition of lipid peroxidation and enhancement of GST activity by cardamom and cinnamon during chemically induced colon carcinogenesis in Swiss albino mice. Asian Pac J Cancer Prev 2007; 8:578-82.
    • (2007) Asian Pac J Cancer Prev , vol.8 , pp. 578-582
    • Bhattacharjee, S.1    Rana, T.2    Sengupta, A.3
  • 83
    • 2542554241 scopus 로고    scopus 로고
    • Saffron can prevent chemically induced skin carcinogenesis in Swiss albino mice
    • Das I, Chakrabarty RN, Das S. Saffron can prevent chemically induced skin carcinogenesis in Swiss albino mice. Asian Pac J Cancer Prev 2004; 5:70-6.
    • (2004) Asian Pac J Cancer Prev , vol.5 , pp. 70-76
    • Das, I.1    Chakrabarty, R.N.2    Das, S.3
  • 84
    • 77953459448 scopus 로고    scopus 로고
    • Saffron suppresses oxidative stress in DMBA-induced skin carcinoma: A histopathological study
    • Das I, Das S, Saha T. Saffron suppresses oxidative stress in DMBA-induced skin carcinoma: A histopathological study. Acta Histochem 2009; 26:26.
    • (2009) Acta Histochem , vol.26 , pp. 26
    • Das, I.1    Das, S.2    Saha, T.3
  • 85
    • 60749085613 scopus 로고    scopus 로고
    • Effect of garlic on lipid peroxidation and antioxidation enzymes in DMBA-induced skin carcinoma
    • Das I, Saha T. Effect of garlic on lipid peroxidation and antioxidation enzymes in DMBA-induced skin carcinoma. Nutrition 2009; 25:459-71.
    • (2009) Nutrition , vol.25 , pp. 459-471
    • Das, I.1    Saha, T.2
  • 86
    • 43749107872 scopus 로고    scopus 로고
    • The role of herbs and spices in cancer prevention
    • Kaefer CM, Milner JA. The role of herbs and spices in cancer prevention. J Nutr Biochem 2008; 19:347-61.
    • (2008) J Nutr Biochem , vol.19 , pp. 347-361
    • Kaefer, C.M.1    Milner, J.A.2
  • 87
    • 0042011407 scopus 로고    scopus 로고
    • Chemopreventive potential of volatile oil from black cumin (Nigella sativa L.) seeds against rat colon carcinogenesis
    • Salim EI, Fukushima S. Chemopreventive potential of volatile oil from black cumin (Nigella sativa L.) seeds against rat colon carcinogenesis. Nutr Cancer 2003; 45:195-202.
    • (2003) Nutr Cancer , vol.45 , pp. 195-202
    • Salim, E.I.1    Fukushima, S.2
  • 88
    • 33751522909 scopus 로고    scopus 로고
    • The redox regulation of thiol dependent signaling pathways in cancer
    • Giles GI. The redox regulation of thiol dependent signaling pathways in cancer. Curr Pharm Des 2006; 12:4427-43.
    • (2006) Curr Pharm Des , vol.12 , pp. 4427-4443
    • Giles, G.I.1
  • 89
    • 33947381788 scopus 로고    scopus 로고
    • Redox in redux: Emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation
    • Tew KD. Redox in redux: Emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation. Biochem Pharmacol 2007; 73:1257-69.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1257-1269
    • Tew, K.D.1
  • 90
    • 40049088820 scopus 로고    scopus 로고
    • The Nrf2-Keap1 defence pathway: Role in protection against drug-induced toxicity
    • Copple IM, Goldring CE, Kitteringham NR, Park BK. The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity. Toxicology 2008; 246:24-33.
    • (2008) Toxicology , vol.246 , pp. 24-33
    • Copple, I.M.1    Goldring, C.E.2    Kitteringham, N.R.3    Park, B.K.4
  • 91
    • 33646675588 scopus 로고    scopus 로고
    • Protective mechanism against oxidative stress by Keap1/Nrf2 pathway
    • Itoh K. Protective mechanism against oxidative stress by Keap1/Nrf2 pathway. Seikagaku 2006; 78:79-92.
    • (2006) Seikagaku , vol.78 , pp. 79-92
    • Itoh, K.1
  • 92
    • 33845442925 scopus 로고    scopus 로고
    • Mechanistic studies of the Nrf2-Keap1 signaling pathway
    • Zhang DD. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab Rev 2006; 38:769-89.
    • (2006) Drug Metab Rev , vol.38 , pp. 769-789
    • Zhang, D.D.1
  • 93
    • 2342514015 scopus 로고    scopus 로고
    • An important role of Nrf2- ARE pathway in the cellular defense mechanism
    • Lee JM, Johnson JA. An important role of Nrf2- ARE pathway in the cellular defense mechanism. J Biochem Mol Biol 2004; 37:139-43.
    • (2004) J Biochem Mol Biol , vol.37 , pp. 139-143
    • Lee, J.M.1    Johnson, J.A.2
  • 94
    • 33748052967 scopus 로고    scopus 로고
    • Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species
    • Kobayashi M, Yamamoto M. Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. Adv Enzyme Regul 2006; 46:113-40.
    • (2006) Adv Enzyme Regul , vol.46 , pp. 113-140
    • Kobayashi, M.1    Yamamoto, M.2
  • 95
    • 44849083150 scopus 로고    scopus 로고
    • Endogenous hydrogen peroxide regulates glutathione redox via nuclear factor erythroid 2-related factor 2 downstream of phosphatidylinositol 3-kinase during muscle differentiation
    • Ding Y, Choi KJ, Kim JH, Han X, Piao Y, Jeong JH, et al. Endogenous hydrogen peroxide regulates glutathione redox via nuclear factor erythroid 2-related factor 2 downstream of phosphatidylinositol 3-kinase during muscle differentiation. Am J Pathol 2008; 172:1529-41.
    • (2008) Am J Pathol , vol.172 , pp. 1529-1541
    • Ding, Y.1    Choi, K.J.2    Kim, J.H.3    Han, X.4    Piao, Y.5    Jeong, J.H.6
  • 96
    • 63449131459 scopus 로고    scopus 로고
    • Regulation of shear-induced nuclear translocation of the Nrf2 transcription factor in endothelial cells
    • Hsieh CY, Hsiao HY, Wu WY, Liu CA, Tsai YC, Chao YJ, et al. Regulation of shear-induced nuclear translocation of the Nrf2 transcription factor in endothelial cells. J Biomed Sci 2009; 16:12.
    • (2009) J Biomed Sci , vol.16 , pp. 12
    • Hsieh, C.Y.1    Hsiao, H.Y.2    Wu, W.Y.3    Liu, C.A.4    Tsai, Y.C.5    Chao, Y.J.6
  • 97
    • 56249106571 scopus 로고    scopus 로고
    • Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals
    • Surh YJ, Kundu JK, Na HK. Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals. Planta Med 2008; 74:1526-39.
    • (2008) Planta Med , vol.74 , pp. 1526-1539
    • Surh, Y.J.1    Kundu, J.K.2    Na, H.K.3
  • 98
    • 58649100237 scopus 로고    scopus 로고
    • Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress
    • Harvey CJ, Thimmulappa RK, Singh A, Blake DJ, Ling G, Wakabayashi N, et al. Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress. Free Radic Biol Med 2009; 46:443-53.
    • (2009) Free Radic Biol Med , vol.46 , pp. 443-453
    • Harvey, C.J.1    Thimmulappa, R.K.2    Singh, A.3    Blake, D.J.4    Ling, G.5    Wakabayashi, N.6
  • 99
    • 59549099432 scopus 로고    scopus 로고
    • Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury
    • 725174
    • Jin W, Wang H, Yan W, Xu L, Wang X, Zhao X, et al. Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury. Mediators Inflamm 2008; 725174:25.
    • (2008) Mediators Inflamm , pp. 25
    • Jin, W.1    Wang, H.2    Yan, W.3    Xu, L.4    Wang, X.5    Zhao, X.6
  • 100
    • 46649112474 scopus 로고    scopus 로고
    • Increased expression of Nrf2/AREdependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells
    • Kim SK, Yang JW, Kim MR, Roh SH, Kim HG, Lee KY, et al. Increased expression of Nrf2/AREdependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells. Free Radic Biol Med 2008; 45:537-46.
    • (2008) Free Radic Biol Med , vol.45 , pp. 537-546
    • Kim, S.K.1    Yang, J.W.2    Kim, M.R.3    Roh, S.H.4    Kim, H.G.5    Lee, K.Y.6
  • 101
    • 77953450621 scopus 로고    scopus 로고
    • The vitamin a family can significantly decrease the expression of ERbeta of ERs positive breast cancer cells in the presence or absence of ER ligands and paclitaxel
    • Czeczuga-Semeniuk E, Jarzabek K, Lemancewicz D, Wolczynski S. The vitamin A family can significantly decrease the expression of ERbeta of ERs positive breast cancer cells in the presence or absence of ER ligands and paclitaxel. Gynecol Endocrinol 2009; 26:1-7.
    • (2009) Gynecol Endocrinol , vol.26 , pp. 1-7
    • Czeczuga-Semeniuk, E.1    Jarzabek, K.2    Lemancewicz, D.3    Wolczynski, S.4
  • 102
    • 56749160147 scopus 로고    scopus 로고
    • NRF2 as a determinant of cellular resistance in retinoic acid cytotoxicity
    • Tan KP, Kosuge K, Yang M, Ito S. NRF2 as a determinant of cellular resistance in retinoic acid cytotoxicity. Free Radic Biol Med 2008; 45:1663-73.
    • (2008) Free Radic Biol Med , vol.45 , pp. 1663-1673
    • Tan, K.P.1    Kosuge, K.2    Yang, M.3    Ito, S.4
  • 103
    • 47549098593 scopus 로고    scopus 로고
    • The role of Nrf2 in increased reactive oxygen species and DNA damage in prostate tumorigenesis
    • Frohlich DA, McCabe MT, Arnold RS, Day ML. The role of Nrf2 in increased reactive oxygen species and DNA damage in prostate tumorigenesis. Oncogene 2008; 27:4353-62.
    • (2008) Oncogene , vol.27 , pp. 4353-4362
    • Frohlich, D.A.1    McCabe, M.T.2    Arnold, R.S.3    Day, M.L.4
  • 104
    • 77953461403 scopus 로고    scopus 로고
    • Redox regulation of NFkappaB: From basic to clinical research
    • Antunes F, Han D. Redox Regulation of NFkappaB: from basic to clinical research. Antioxid Redox Signal 2009; 13:13.
    • (2009) Antioxid Redox Signal , vol.13 , pp. 13
    • Antunes, F.1    Han, D.2
  • 105
    • 63149160727 scopus 로고    scopus 로고
    • Regulation of macrophage function in tumors: The multifaceted role of NFkappaB
    • Hagemann T, Biswas SK, Lawrence T, Sica A, Lewis CE. Regulation of macrophage function in tumors: the multifaceted role of NFkappaB. Blood 2009; 113:3139-46.
    • (2009) Blood , vol.113 , pp. 3139-3146
    • Hagemann, T.1    Biswas, S.K.2    Lawrence, T.3    Sica, A.4    Lewis, C.E.5
  • 107
    • 67650376399 scopus 로고    scopus 로고
    • The NFkappaB transcription factor pathway as a therapeutic target in cancer: Methods for detection of NFkappaB activity
    • Mauro C, Zazzeroni F, Papa S, Bubici C, Franzoso G. The NFkappaB transcription factor pathway as a therapeutic target in cancer: methods for detection of NFkappaB activity. Methods Mol Biol 2009; 512:169-207.
    • (2009) Methods Mol Biol , vol.512 , pp. 169-207
    • Mauro, C.1    Zazzeroni, F.2    Papa, S.3    Bubici, C.4    Franzoso, G.5
  • 108
    • 59149093518 scopus 로고    scopus 로고
    • Critical role of IkappaB kinase alpha in embryonic skin development and skin carcinogenesis
    • Zhu F, Park E, Liu B, Xia X, Fischer SM, Hu Y. Critical role of IkappaB kinase alpha in embryonic skin development and skin carcinogenesis. Histol Histopathol 2009; 24:265-71.
    • (2009) Histol Histopathol , vol.24 , pp. 265-271
    • Zhu, F.1    Park, E.2    Liu, B.3    Xia, X.4    Fischer, S.M.5    Hu, Y.6
  • 109
    • 65549134351 scopus 로고    scopus 로고
    • Inhibition of constitutively activated nuclear factor-kappaB induces reactive oxygen species- and iron-dependent cell death in cutaneous T-cell lymphoma
    • Kiessling MK, Klemke CD, Kaminski MM, Galani IE, Krammer PH, Gulow K. Inhibition of constitutively activated nuclear factor-kappaB induces reactive oxygen species- and iron-dependent cell death in cutaneous T-cell lymphoma. Cancer Res 2009; 69:2365-74.
    • (2009) Cancer Res , vol.69 , pp. 2365-2374
    • Kiessling, M.K.1    Klemke, C.D.2    Kaminski, M.M.3    Galani, I.E.4    Krammer, P.H.5    Gulow, K.6
  • 110
    • 65549104414 scopus 로고    scopus 로고
    • 4-hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells via activation of IkappaB kinase: Potential role of reactive oxygen species
    • Park SA, Na HK, Kim EH, Cha YN, Surh YJ. 4-hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells via activation of IkappaB kinase: potential role of reactive oxygen species. Cancer Res 2009; 69:2416-24.
    • (2009) Cancer Res , vol.69 , pp. 2416-2424
    • Park, S.A.1    Na, H.K.2    Kim, E.H.3    Cha, Y.N.4    Surh, Y.J.5
  • 111
    • 61649109480 scopus 로고    scopus 로고
    • Sodium arsenite induces ROS generation, DNA oxidative damage, HO-1 and c-Myc proteins, NFkappaB activation and cell proliferation in human breast cancer MCF-7 cells
    • Ruiz-Ramos R, Lopez-Carrillo L, Rios-Perez AD, De Vizcaya-Ruiz A, Cebrian ME. Sodium arsenite induces ROS generation, DNA oxidative damage, HO-1 and c-Myc proteins, NFkappaB activation and cell proliferation in human breast cancer MCF-7 cells. Mutat Res 2009; 674:109-15.
    • (2009) Mutat Res , vol.674 , pp. 109-115
    • Ruiz-Ramos, R.1    Lopez-Carrillo, L.2    Rios-Perez, A.D.3    De Vizcaya-Ruiz, A.4    Cebrian, M.E.5
  • 113
    • 41749092315 scopus 로고    scopus 로고
    • Catalase overexpression impairs TNFalpha induced NFkappaB activation and sensitizes MCF-7 cells against TNFalpha
    • Lupertz R, Chovolou Y, Kampkotter A, Watjen W, Kahl R. Catalase overexpression impairs TNFalpha induced NFkappaB activation and sensitizes MCF-7 cells against TNFalpha. J Cell Biochem 2008; 103:1497-511.
    • (2008) J Cell Biochem , vol.103 , pp. 1497-1511
    • Lupertz, R.1    Chovolou, Y.2    Kampkotter, A.3    Watjen, W.4    Kahl, R.5
  • 114
    • 58249118720 scopus 로고    scopus 로고
    • Oxidative, multistep activation of the noncanonical NFkappaB pathway via disulfide Bcl-3/p50 complex
    • Cristofanon S, Morceau F, Scovassi AI, Dicato M, Ghibelli L, Diederich M. Oxidative, multistep activation of the noncanonical NFkappaB pathway via disulfide Bcl-3/p50 complex. Faseb J 2009; 23:45-57.
    • (2009) Faseb J , vol.23 , pp. 45-57
    • Cristofanon, S.1    Morceau, F.2    Scovassi, A.I.3    Dicato, M.4    Ghibelli, L.5    Diederich, M.6
  • 115
    • 37249091222 scopus 로고    scopus 로고
    • Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells
    • Jimenez-Lopez JM, Wu D, Cederbaum AI. Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells. Toxicol In Vitro 2008; 22:106-15.
    • (2008) Toxicol in Vitro , vol.22 , pp. 106-115
    • Jimenez-Lopez, J.M.1    Wu, D.2    Cederbaum, A.I.3
  • 116
    • 53949090765 scopus 로고    scopus 로고
    • NFkappaB signaling pathway and its therapeutic implications in human diseases
    • Sarkar FH, Li Y, Wang Z, Kong D. NFkappaB signaling pathway and its therapeutic implications in human diseases. Int Rev Immunol 2008; 27:293-319.
    • (2008) Int Rev Immunol , vol.27 , pp. 293-319
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4
  • 118
    • 0038449134 scopus 로고    scopus 로고
    • Overexpression of the transgene for manganese superoxide dismutase (MnSOD) in 32D cl 3 cells prevents apoptosis induction by TNFalpha, IL-3 withdrawal, and ionizing radiation
    • Epperly MW, Bernarding M, Gretton J, Jefferson M, Nie S, Greenberger JS. Overexpression of the transgene for manganese superoxide dismutase (MnSOD) in 32D cl 3 cells prevents apoptosis induction by TNFalpha, IL-3 withdrawal, and ionizing radiation. Exp Hematol 2003; 31:465-74.
    • (2003) Exp Hematol , vol.31 , pp. 465-474
    • Epperly, M.W.1    Bernarding, M.2    Gretton, J.3    Jefferson, M.4    Nie, S.5    Greenberger, J.S.6
  • 119
    • 0038069301 scopus 로고    scopus 로고
    • Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation
    • Place RF, Haspeslagh D, Giardina C. Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation. J Cell Physiol 2003; 195:470-8.
    • (2003) J Cell Physiol , vol.195 , pp. 470-478
    • Place, R.F.1    Haspeslagh, D.2    Giardina, C.3
  • 120
    • 65049091645 scopus 로고    scopus 로고
    • Signal transduction in pancreatic stellate cells
    • Masamune A, Shimosegawa T. Signal transduction in pancreatic stellate cells. J Gastroenterol 2009; 44:249-60.
    • (2009) J Gastroenterol , vol.44 , pp. 249-260
    • Masamune, A.1    Shimosegawa, T.2
  • 121
    • 0037312590 scopus 로고    scopus 로고
    • Beta-carotene regulates NFkappaB DNA-binding activity by a redox mechanism in human leukemia and colon adenocarcinoma cells
    • Palozza P, Serini S, Torsello A, Di Nicuolo F, Piccioni E, Ubaldi V, et al. Beta-carotene regulates NFkappaB DNA-binding activity by a redox mechanism in human leukemia and colon adenocarcinoma cells. J Nutr 2003; 133:381-8.
    • (2003) J Nutr , vol.133 , pp. 381-388
    • Palozza, P.1    Serini, S.2    Torsello, A.3    Di Nicuolo, F.4    Piccioni, E.5    Ubaldi, V.6
  • 122
    • 41349115251 scopus 로고    scopus 로고
    • Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: Involvement of caspase-3, NFkappaB and ERK-2
    • Sriram N, Kalayarasan S, Ashokkumar P, Sureshkumar A, Sudhandiran G. Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NFkappaB and ERK-2. Mol Cell Biochem 2008; 311:157-65.
    • (2008) Mol Cell Biochem , vol.311 , pp. 157-165
    • Sriram, N.1    Kalayarasan, S.2    Ashokkumar, P.3    Sureshkumar, A.4    Sudhandiran, G.5
  • 123
    • 41549160315 scopus 로고    scopus 로고
    • Phosphatasemediated crosstalk between MAPK signaling pathways in the regulation of cell survival
    • Junttila MR, Li SP, Westermarck J. Phosphatasemediated crosstalk between MAPK signaling pathways in the regulation of cell survival. Faseb J 2008; 22:954-65.
    • (2008) Faseb J , vol.22 , pp. 954-965
    • Junttila, M.R.1    Li, S.P.2    Westermarck, J.3
  • 124
    • 65949119310 scopus 로고    scopus 로고
    • How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
    • Mebratu Y, Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle 2009; 8:1168-75.
    • (2009) Cell Cycle , vol.8 , pp. 1168-1175
    • Mebratu, Y.1    Tesfaigzi, Y.2
  • 125
    • 42449146501 scopus 로고    scopus 로고
    • Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy
    • McCubrey JA, Steelman LS, Abrams SL, Bertrand FE, Ludwig DE, Basecke J, et al. Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. Leukemia 2008; 22:708-22.
    • (2008) Leukemia , vol.22 , pp. 708-722
    • McCubrey, J.A.1    Steelman, L.S.2    Abrams, S.L.3    Bertrand, F.E.4    Ludwig, D.E.5    Basecke, J.6
  • 127
    • 0141864346 scopus 로고    scopus 로고
    • Role of MAPK phosphorylation in cytoprotection by pro-vitamin C against oxidative stress-induced injuries in cultured cardiomyoblasts and perfused rat heart
    • Eguchi M, Monden K, Miwa N. Role of MAPK phosphorylation in cytoprotection by pro-vitamin C against oxidative stress-induced injuries in cultured cardiomyoblasts and perfused rat heart. J Cell Biochem 2003; 90:219-26.
    • (2003) J Cell Biochem , vol.90 , pp. 219-226
    • Eguchi, M.1    Monden, K.2    Miwa, N.3
  • 128
    • 62549090206 scopus 로고    scopus 로고
    • Acute adrenergic stress inhibits proliferation of murine hematopoietic progenitor cells via p38/MAPK signaling
    • Schraml E, Fuchs R, Kotzbeck P, Grillari J, Schauenstein K. Acute adrenergic stress inhibits proliferation of murine hematopoietic progenitor cells via p38/MAPK signaling. Stem Cells Dev 2009; 18:215-27.
    • (2009) Stem Cells Dev , vol.18 , pp. 215-227
    • Schraml, E.1    Fuchs, R.2    Kotzbeck, P.3    Grillari, J.4    Schauenstein, K.5
  • 129
    • 50949084572 scopus 로고    scopus 로고
    • Co-opted JNK/SAPK signaling in Wnt/beta-catenin-induced tumorigenesis
    • Liu B, Yu HM, Huang J, Hsu W. Co-opted JNK/SAPK signaling in Wnt/beta-catenin-induced tumorigenesis. Neoplasia 2008; 10:1004-13.
    • (2008) Neoplasia , vol.10 , pp. 1004-1013
    • Liu, B.1    Yu, H.M.2    Huang, J.3    Hsu, W.4
  • 130
    • 30644468596 scopus 로고    scopus 로고
    • JNK/SAPK and p38 SAPK-2 mediate mechanical stretch-induced apoptosis via caspase-3 and -9 in NRK-52E renal epithelial cells
    • Nguyen HT, Hsieh MH, Gaborro A, Tinloy B, Phillips C, Adam RM. JNK/SAPK and p38 SAPK-2 mediate mechanical stretch-induced apoptosis via caspase-3 and -9 in NRK-52E renal epithelial cells. Nephron Exp Nephrol 2006; 102:22.
    • (2006) Nephron Exp Nephrol , vol.102 , pp. 22
    • Nguyen, H.T.1    Hsieh, M.H.2    Gaborro, A.3    Tinloy, B.4    Phillips, C.5    Adam, R.M.6
  • 131
    • 49349083531 scopus 로고    scopus 로고
    • Redox control of cell fate by MAP kinase: Physiological roles of ASK1-MAP kinase pathway in stress signaling
    • Matsuzawa A, Ichijo H. Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling. Biochim Biophys Acta 2008; 1780:1325-36.
    • (2008) Biochim Biophys Acta , vol.1780 , pp. 1325-1336
    • Matsuzawa, A.1    Ichijo, H.2
  • 132
    • 34948845017 scopus 로고    scopus 로고
    • Disulfide Bond-mediated multimerization of Ask1 and its reduction by thioredoxin-1 regulate H(2) O(2)-induced c-Jun NH(2)-terminal kinase activation and apoptosis
    • Nadeau PJ, Charette SJ, Toledano MB, Landry J. Disulfide Bond-mediated multimerization of Ask1 and its reduction by thioredoxin-1 regulate H(2) O(2)-induced c-Jun NH(2)-terminal kinase activation and apoptosis. Mol Biol Cell 2007; 18:3903-13.
    • (2007) Mol Biol Cell , vol.18 , pp. 3903-3913
    • Nadeau, P.J.1    Charette, S.J.2    Toledano, M.B.3    Landry, J.4
  • 133
    • 0012449739 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways in redox signaling
    • Torres M. Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 2003; 8:369-91.
    • (2003) Front Biosci , vol.8 , pp. 369-391
    • Torres, M.1
  • 134
    • 66149104809 scopus 로고    scopus 로고
    • Stanniocalcin-1 acts in a negative feedback loop in the prosurvival ERK1/2 signaling pathway during oxidative stress
    • Nguyen A, Chang AC, Reddel RR. Stanniocalcin-1 acts in a negative feedback loop in the prosurvival ERK1/2 signaling pathway during oxidative stress. Oncogene 2009; 28:1982-92.
    • (2009) Oncogene , vol.28 , pp. 1982-1992
    • Nguyen, A.1    Chang, A.C.2    Reddel, R.R.3
  • 135
    • 67349252446 scopus 로고    scopus 로고
    • Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells
    • Kang GY, Lee ER, Kim JH, Jung JW, Lim J, Kim SK, et al. Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells. Eur J Pharmacol 2009; 611:17-21.
    • (2009) Eur J Pharmacol , vol.611 , pp. 17-21
    • Kang, G.Y.1    Lee, E.R.2    Kim, J.H.3    Jung, J.W.4    Lim, J.5    Kim, S.K.6
  • 136
    • 47949120075 scopus 로고    scopus 로고
    • Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition
    • Kim BW, Lee ER, Min HM, Jeong HS, Ahn JY, Kim JH, et al. Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition. Cancer Biol Ther 2008; 7:1080-9.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1080-1089
    • Kim, B.W.1    Lee, E.R.2    Min, H.M.3    Jeong, H.S.4    Ahn, J.Y.5    Kim, J.H.6
  • 137
    • 35048858737 scopus 로고    scopus 로고
    • Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c- Jun activation
    • Shim HY, Park JH, Paik HD, Nah SY, Kim DS, Han YS. Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c- Jun activation. Mol Cells 2007; 24:95-104.
    • (2007) Mol Cells , vol.24 , pp. 95-104
    • Shim, H.Y.1    Park, J.H.2    Paik, H.D.3    Nah, S.Y.4    Kim, D.S.5    Han, Y.S.6
  • 138
    • 43449121225 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species/c-Jun NH(2)- Terminal kinase pathway in kotomolide A induces apoptosis in human breast cancer cells
    • Kuo PL, Chen CY, Tzeng TF, Lin CC, Hsu YL. Involvement of reactive oxygen species/c-Jun NH(2)- terminal kinase pathway in kotomolide A induces apoptosis in human breast cancer cells. Toxicol Appl Pharmacol 2008; 229:215-26.
    • (2008) Toxicol Appl Pharmacol , vol.229 , pp. 215-226
    • Kuo, P.L.1    Chen, C.Y.2    Tzeng, T.F.3    Lin, C.C.4    Hsu, Y.L.5
  • 139
    • 33748324473 scopus 로고    scopus 로고
    • Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate
    • Donadelli M, Dalla Pozza E, Costanzo C, Scupoli MT, Piacentini P, Scarpa A, et al. Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate. Biochim Biophys Acta 2006; 1763:917-26.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 917-926
    • Donadelli, M.1    Dalla, P.E.2    Costanzo, C.3    Scupoli, M.T.4    Piacentini, P.5    Scarpa, A.6
  • 140
    • 34848844388 scopus 로고    scopus 로고
    • Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL
    • Hsu WH, Hsieh YS, Kuo HC, Teng CY, Huang HI, Wang CJ, et al. Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL. Arch Toxicol 2007; 81:719-28.
    • (2007) Arch Toxicol , vol.81 , pp. 719-728
    • Hsu, W.H.1    Hsieh, Y.S.2    Kuo, H.C.3    Teng, C.Y.4    Huang, H.I.5    Wang, C.J.6
  • 141
    • 33748671329 scopus 로고    scopus 로고
    • Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: The role of ROS/superoxides, NFAT and MEK/ERK signaling
    • Liu Y, Borchert GL, Surazynski A, Hu CA, Phang JM. Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling. Oncogene 2006; 25:5640-7.
    • (2006) Oncogene , vol.25 , pp. 5640-5647
    • Liu, Y.1    Borchert, G.L.2    Surazynski, A.3    Hu, C.A.4    Phang, J.M.5
  • 142
    • 67649970221 scopus 로고    scopus 로고
    • Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: Therapeutic implications for prostate cancer
    • Joo SS, Yoo YM. Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer. J Pineal Res 2009; 47:8-14.
    • (2009) J Pineal Res , vol.47 , pp. 8-14
    • Joo, S.S.1    Yoo, Y.M.2
  • 143
    • 51349111250 scopus 로고    scopus 로고
    • Targeting AKT/mTOR and ERK MAPK signaling inhibits hormonerefractory prostate cancer in a preclinical mouse model
    • Kinkade CW, Castillo-Martin M, Puzio-Kuter A, Yan J, Foster TH, Gao H, et al. Targeting AKT/mTOR and ERK MAPK signaling inhibits hormonerefractory prostate cancer in a preclinical mouse model. J Clin Invest 2008; 118:3051-64.
    • (2008) J Clin Invest , vol.118 , pp. 3051-3064
    • Kinkade, C.W.1    Castillo-Martin, M.2    Puzio-Kuter, A.3    Yan, J.4    Foster, T.H.5    Gao, H.6
  • 144
    • 34848895758 scopus 로고    scopus 로고
    • Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase and JNK activation
    • Sanchez AM, Malagarie-Cazenave S, Olea N, Vara D, Chiloeches A, Diaz-Laviada I. Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase and JNK activation. Apoptosis 2007; 12:2013-24.
    • (2007) Apoptosis , vol.12 , pp. 2013-2024
    • Sanchez, A.M.1    Malagarie-Cazenave, S.2    Olea, N.3    Vara, D.4    Chiloeches, A.5    Diaz-Laviada, I.6
  • 145
    • 60549094472 scopus 로고    scopus 로고
    • Synthesis, oxidant properties and antitumoral effects of a heteroleptic palladium(II) complex of curcumin on human prostate cancer cells
    • Valentini A, Conforti F, Crispini A, De Martino A, Condello R, Stellitano C, et al. Synthesis, oxidant properties and antitumoral effects of a heteroleptic palladium(II) complex of curcumin on human prostate cancer cells. J Med Chem 2009; 52:484-91.
    • (2009) J Med Chem , vol.52 , pp. 484-491
    • Valentini, A.1    Conforti, F.2    Crispini, A.3    De Martino, A.4    Condello, R.5    Stellitano, C.6
  • 146
    • 33646517942 scopus 로고    scopus 로고
    • Accumulation of hydrogen peroxide is an early and crucial step for paclitaxelinduced cancer cell death both in vitro and in vivo
    • Alexandre J, Batteux F, Nicco C, Chereau C, Laurent A, Guillevin L, et al. Accumulation of hydrogen peroxide is an early and crucial step for paclitaxelinduced cancer cell death both in vitro and in vivo. Int J Cancer 2006; 119:41-8.
    • (2006) Int J Cancer , vol.119 , pp. 41-48
    • Alexandre, J.1    Batteux, F.2    Nicco, C.3    Chereau, C.4    Laurent, A.5    Guillevin, L.6
  • 148
    • 39649085170 scopus 로고    scopus 로고
    • Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1, 2, 4-thiadiazolidine, 3, 5 dione (TDZD-8)
    • Guzman ML, Li X, Corbett CA, Rossi RM, Bushnell T, Liesveld JL, et al. Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1, 2, 4-thiadiazolidine, 3, 5 dione (TDZD-8). Blood 2007; 110:4436-44.
    • (2007) Blood , vol.110 , pp. 4436-4444
    • Guzman, M.L.1    Li, X.2    Corbett, C.A.3    Rossi, R.M.4    Bushnell, T.5    Liesveld, J.L.6


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