Synthesis, oxidant properties, and antitumoral effects of a heteroleptic palladium(II) complex of curcumin on human prostate cancer cells

Journal of Medicinal Chemistry

Volumn 52, Issue 2, 2009, Pages 484-491

  Valentini, Alessandra ^a   Conforti, Franco ^a   Crispini, Alessandra ^b   De Martino, Angelo ^c   Condello, Rossella ^a   Stellitano, Chiara ^a   Rotilio, Giuseppe ^c   Ghedini, Mauro ^b   Federici, Giorgio ^a   Bernardini, Sergio ^a   Pucci, Daniela ^b  

^a TOR VERGATA UNIVERSITY HOSPITAL   (Italy)

^b UNIVERSITY OF CALABRIA   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' DINONYL 2,2' BIPYRIDINE PALLADIUM CURCUMIN TRIFLUOROMETHANESULFONATE; CURCUMIN; GLUTATHIONE TRANSFERASE P1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PALLADIUM COMPLEX; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; OXIDIZING AGENT; PALLADIUM;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRAIN LNCAP; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRUG SYNTHESIS; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; PROSTATE CANCER; REACTION ANALYSIS; SIGNAL TRANSDUCTION; UPREGULATION; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; SYNTHESIS; TUMOR CELL LINE; ULTRAVIOLET SPECTROPHOTOMETRY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CURCUMIN; DNA DAMAGE; HUMANS; MALE; MAP KINASE KINASE 4; OXIDANTS; PALLADIUM; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 60549094472     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm801276a     Document Type: Article

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