Targeted inhibition of glucuronidation markedly improves drug efficacy in mice-A model

Biochemical and Biophysical Research Communications

Volumn 360, Issue 1, 2007, Pages 7-13

  Basu, Nikhil K ^a   Kole, Labanyamoy ^a   Basu, Mousumi ^a   McDonagh, Antony F ^b   Owens, Ida S ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b the Liver Center   (United States)

Author keywords

Calphostin C; CTL assay; Curcumin; Drug efficacy; Immunosupression; Mycophenolic acid; Phosphorylation; PKC; Proof of principle; UDP glucuronosyltransferase

Indexed keywords

CALPHOSTIN C; CURCUMIN; GLUCURONOSYLTRANSFERASE; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; DRUG METABOLISM; GLUCURONIDATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; CURCUMIN; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; DUODENITIS; GLUCURONOSYLTRANSFERASE; IMMUNOSUPPRESSIVE AGENTS; MICE; MYCOPHENOLIC ACID; PROTEIN KINASE C; TREATMENT OUTCOME;

MUS;

EID: 34250851354     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.05.224     Document Type: Article

References (22)

1. Basu N.K., Ciotti M., Hwang M.S., Kole L., Mitra P.S., Cho J.W., and Owens I.S. J. Biol. Chem. 279 (2004) 1429-1441
2. Basu N.K., Kovarova M., Garza A., Kubota S., Saha T., Mitra P.S., Banerjee R., Rivera J., and Owens I.S. Proc. Natl. Acad. Sci. USA 102 (2005) 6285-6290
3. Basu N.K., Kole L., and Owens I.S. Biochem. Biophys. Res. Commun. 303 (2003) 98-104
4. Allison A.C., and Eugui E.M. Transplantation 80 (2005) S181-S190
5. MacPhee I.A.M., Spreafico S., Bewick M., Davis C., Eastwood J.B., Johnston A., Lee T., and Holt D.W. Kidney Internat. 57 (2000) 1164-1168
6. Eugui E.M., Mirkovich A., and Allison A.C. Scand. J. Immunol. 33 (1991) 175-183
7. Sintchak M.D., Fleming M.A., Futer O., Raybuck S.A., Chambers S.P., Caron P.R., Murcko M.A., and Wilson K.P. Cell 85 (1996) 921-930
8. Cohn R.G., Mirkovich A., Dunlap B., Burton P., Chiu S.H., Eugui E., and Caulfield J.P. Transplantation 68 (1999) 411-418
9. Wieland E., Shipkova M., Schellhaas U., Shütz E., Niedmann P.D., Armstrong V.W., and Oellerich M. Clin. Biochem. 33 (2000) 107-113
10. Shipkova M., Beck H., Voland A., Armstrong V.W., Hermann-Josef G., Oellerich M., and Wieland E. Proteomics 4 (2004) 2728-2738
11. Shipkova M., Armstrong V.M., Wieland E., Niedmann P.D., Schütz E., Brenner-Weiss G., Voihsel M., Braun F., and Oellerich M. Br. J. Pharmacol. 126 (1999) 1075-1082
12. Basu N.K., Kole L., Kubota S., and Owens I.S. Drug Metab. Dispos. 32 (2004) 768-773
13. Lin J.K. Arch. Pharm. Res. 27 (2004) 683-692
14. Zhang T., Haws P., and Wu Q. Genome Res. 14 (2004) 79-89
15. Mackenzie P.I. Ther. Drug Monit. 22 (2000) 10-13
16. Garcea G., Berry D.P., Jones D.J., Singh R., Dennison A.R., Farmer P.B., Sharma R.A., Steward W.P., and Gescher A.J. Cancer Epidemiol. Biomarkers Prev. 14 (2000) 120-125
17. Cheng A.L., Hsu C.H., Lin J.K., Hsu M.M., Ho Y.F., Shen T.S., Ko J.Y., Lin J.T., Lin B.R., Ming-Shiang W., Yu H.S., Jee S.H., Chen G.S., Chen T.M., Chen C.A., Lai M.K., Pu Y.S., Pan M.H., Wang Y.J., Tsai C.C., and Hsieh C.Y. Anticancer Res. 21 (2001) 2895-2900
18. Lang S., Picu A., Hofmann T., Andratschke M., Mack B., Moosmann A., Gires O., Tiwari S., and Zeidler R. Int. J. Immunopathol. Pharmacol. 19 (2006) 409-419
19. Gopalakrishna R., and Jaken S. Free Radic. Biol. Med. 28 (2000) 1349-1361
20. Dorai T., and Aggarwal B.B. Cancer Lett. 215 (2004) 129-140
21. Churchill M., Chadburn A., Bilinski R.T., and Bertagnolli M.M. J. Surg. Res. 89 (2000) 169-175
22. Pereira M.A., Grubbs C.J., Barnes L.H., Li H., Olson G.R., Eto I., Juliana M., Whitaker L.M., Kelloff G.J., Steele V.E., and Lubet R.A. Carcinogenesis 17 (1996) 1305-1311