-
1
-
-
0038644536
-
Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
-
Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology 2003; 37:1202-1219.
-
(2003)
Hepatology
, vol.37
, pp. 1202-1219
-
-
Neuschwander-Tetri, B.A.1
Caldwell, S.H.2
-
2
-
-
0031947715
-
Steatohepatitis: A tale of two 'hits'?
-
Day CP, James OF. Steatohepatitis: a tale of two 'hits'? Gastroenterology 1998; 114:842-845.
-
(1998)
Gastroenterology
, vol.114
, pp. 842-845
-
-
Day, C.P.1
James, O.F.2
-
3
-
-
22544461356
-
Nonalcoholic fatty liver disease and the metabolic syndrome
-
Marchesini G, Marzocchi R, Agostini F, Bugianesi E. Nonalcoholic fatty liver disease and the metabolic syndrome. Curr Opin Lipidol 2005; 16:421-427. (Pubitemid 41017626)
-
(2005)
Current Opinion in Lipidology
, vol.16
, Issue.4
, pp. 421-427
-
-
Marchesini, G.1
Marzocchi, R.2
Agostini, F.3
Bugianesi, E.4
-
4
-
-
10644220306
-
Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
-
Browning JD, Szczepaniak LS, Dobbins R, et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004; 40:1387-1395.
-
(2004)
Hepatology
, vol.40
, pp. 1387-1395
-
-
Browning, J.D.1
Szczepaniak, L.S.2
Dobbins, R.3
-
5
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly KL, Smith CI, Schwarzenberg SJ, et al. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 2005; 115:1343-1351.
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
-
6
-
-
10444226462
-
ER stress and the unfolded protein response
-
Schroder M, Kaufman RJ. ER stress and the unfolded protein response. Mutat Res 2005; 569:29-63.
-
(2005)
Mutat Res
, vol.569
, pp. 29-63
-
-
Schroder, M.1
Kaufman, R.J.2
-
7
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding HP, Novoa I, Zhang Y, et al. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 2000; 6:1099-1108.
-
(2000)
Mol Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
-
8
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004; 306:457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
-
9
-
-
40949093618
-
Therapeutic potential of peroxisome pro-liferators-activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes
-
Han KL, Choi JS, Lee JY, et al. Therapeutic potential of peroxisome pro-liferators-activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes. Diabetes 2008; 57:737-745.
-
(2008)
Diabetes
, vol.57
, pp. 737-745
-
-
Han, K.L.1
Choi, J.S.2
Lee, J.Y.3
-
10
-
-
66449137379
-
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
-
Kammoun HL, Chabanon H, Hainault I, et al. GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice. J Clin Invest 2009; 119:1201-1215.
-
(2009)
J Clin Invest
, vol.119
, pp. 1201-1215
-
-
Kammoun, H.L.1
Chabanon, H.2
Hainault, I.3
-
11
-
-
34248681601
-
CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steato-hepatitis
-
Rahman SM, Schroeder-Gloeckler JM, Janssen RC, et al. CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steato-hepatitis. Hepatology 2007; 45:1108-1117.
-
(2007)
Hepatology
, vol.45
, pp. 1108-1117
-
-
Rahman, S.M.1
Schroeder-Gloeckler, J.M.2
Janssen, R.C.3
-
12
-
-
44449126331
-
Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice
-
Sreejayan N, Dong F, Kandadi MR, et al. Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice. Obesity (Silver Spring) 2008; 16:1331-1337.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 1331-1337
-
-
Sreejayan, N.1
Dong, F.2
Kandadi, M.R.3
-
13
-
-
34547932066
-
Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers
-
Yang L, Jhaveri R, Huang J, et al. Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers. Lab Invest 2007; 87:927-937.
-
(2007)
Lab Invest
, vol.87
, pp. 927-937
-
-
Yang, L.1
Jhaveri, R.2
Huang, J.3
-
14
-
-
75949113693
-
Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet
-
Mu YP, Ogawa T, Kawada N. Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline- deficient diet. Lab Invest 2009; 90:245-256.
-
(2009)
Lab Invest
, vol.90
, pp. 245-256
-
-
Mu, Y.P.1
Ogawa, T.2
Kawada, N.3
-
15
-
-
30944451788
-
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis
-
DOI 10.1210/en.2005-0570
-
Wang D, Wei Y, Pagliassotti MJ. Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis. Endocrinology 2006; 147:943-951. (Pubitemid 43113013)
-
(2006)
Endocrinology
, vol.147
, Issue.2
, pp. 943-951
-
-
Wang, D.1
Wei, Y.2
Pagliassotti, M.J.3
-
16
-
-
62749178966
-
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss
-
Gregor MF, Yang L, Fabbrini E, et al. Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes 2009; 58:693-700.
-
(2009)
Diabetes
, vol.58
, pp. 693-700
-
-
Gregor, M.F.1
Yang, L.2
Fabbrini, E.3
-
17
-
-
38649124615
-
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease
-
Puri P, Mirshahi F, Cheung O, et al. Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease. Gastroenterology 2008; 134:568-576.
-
(2008)
Gastroenterology
, vol.134
, pp. 568-576
-
-
Puri, P.1
Mirshahi, F.2
Cheung, O.3
-
18
-
-
45849137877
-
Regulation of hepatic lipogenesis by the transcription factor XBP1
-
Lee AH, Scapa EF, Cohen DE, Glimcher LH. Regulation of hepatic lipogenesis by the transcription factor XBP1. Science 2008; 320:1492-1496.
-
(2008)
Science
, vol.320
, pp. 1492-1496
-
-
Lee, A.H.1
Scapa, E.F.2
Cohen, D.E.3
Glimcher, L.H.4
-
19
-
-
44349163999
-
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatos-teatosis in mice
-
Oyadomari S, Harding HP, Zhang Y, et al. Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatos-teatosis in mice. Cell Metab 2008; 7:520-532.
-
(2008)
Cell Metab
, vol.7
, pp. 520-532
-
-
Oyadomari, S.1
Harding, H.P.2
Zhang, Y.3
-
20
-
-
55849112292
-
PERK-depen-dent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation
-
Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, et al. PERK-depen-dent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation. ProcNatl AcadSci USA 2008; 105:1 6314-16319.
-
(2008)
ProcNatl AcadSci USA
, vol.105
, pp. 16314-16319
-
-
Bobrovnikova-Marjon, E.1
Hatzivassiliou, G.2
Grigoriadou, C.3
-
21
-
-
67650000500
-
ATF6 alpha induces XBP1-independent expansion of the endoplasmic reticulum
-
Bommiasamy H, Back SH, Fagone P, et al. ATF6 alpha induces XBP1-independent expansion of the endoplasmic reticulum. J Cell Sci 2009; 122:1626-1636.
-
(2009)
J Cell Sci
, vol.122
, pp. 1626-1636
-
-
Bommiasamy, H.1
Back, S.H.2
Fagone, P.3
-
22
-
-
34347406521
-
SREBP-1c transcription factor and lipid homeostasis: Clinical perspective
-
Ferré P, Foufelle F. SREBP-1c transcription factor and lipid homeostasis: clinical perspective. Horm Res 2007; 68:72-82.
-
(2007)
Horm Res
, vol.68
, pp. 72-82
-
-
Ferré, P.1
Foufelle, F.2
-
23
-
-
0035514942
-
Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice
-
Bécard D, Hainault I, Azzout-Marniche D, et al. Adenovirus-mediated over-expression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice. Diabetes 2001; 50:2425-2430. (Pubitemid 33642757)
-
(2001)
Diabetes
, vol.50
, Issue.7-12
, pp. 2425-2430
-
-
Becard, D.1
Hainault, I.2
Azzout-Marniche, D.3
Bertry-Coussot, L.4
Ferre, P.5
Foufelle, F.6
-
24
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
-
Shimano H, Horton JD, Shimomura I, et al. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 1997; 99:846-854.
-
(1997)
J Clin Invest
, vol.99
, pp. 846-854
-
-
Shimano, H.1
Horton, J.D.2
Shimomura, I.3
-
25
-
-
0037205433
-
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice
-
Yahagi N, Shimano H, Hasty AH, et al. Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice. J Biol Chem 2002; 277:19353-19357.
-
(2002)
J Biol Chem
, vol.277
, pp. 19353-19357
-
-
Yahagi, N.1
Shimano, H.2
Hasty, A.H.3
-
26
-
-
0033570119
-
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
-
Shimomura I, Bashmakov Y, Horton JD. Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus. J Biol Chem 1999; 274:30028-30032.
-
(1999)
J Biol Chem
, vol.274
, pp. 30028-30032
-
-
Shimomura, I.1
Bashmakov, Y.2
Horton, J.D.3
-
27
-
-
0033636780
-
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipody-strophic and ob/ob mice
-
Shimomura I, Matsuda M, Hammer RE, et al. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipody-strophic and ob/ob mice. Mol Cell 2000; 6:77-86.
-
(2000)
Mol Cell
, vol.6
, pp. 77-86
-
-
Shimomura, I.1
Matsuda, M.2
Hammer, R.E.3
-
28
-
-
53349153430
-
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
-
Higuchi N, Kato M, Shundo Y, Tajiri H, et al. Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. Hepatol Res 2008; 38:1122-1129.
-
(2008)
Hepatol Res
, vol.38
, pp. 1122-1129
-
-
Higuchi, N.1
Kato, M.2
Shundo, Y.3
Tajiri, H.4
-
29
-
-
35148881190
-
Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease
-
Kohjima M, Enjoji M, Higuchi N, et al. Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. Int J Mol Med 2007; 20:351-358.
-
(2007)
Int J Mol Med
, vol.20
, pp. 351-358
-
-
Kohjima, M.1
Enjoji, M.2
Higuchi, N.3
-
30
-
-
29244465372
-
Evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease
-
Nakamuta M, Kohjima M, Morizono S, et al. Evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. Int J Mol Med 2005; 16:631-635.
-
(2005)
Int J Mol Med
, vol.16
, pp. 631-635
-
-
Nakamuta, M.1
Kohjima, M.2
Morizono, S.3
-
31
-
-
21744436422
-
Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs
-
Esfandiari F, Villanueva JA, Wong DH, et al. Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs. Am J Physiol Gastrointest Liver Physiol 2005; 289:G54-G63.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.289
-
-
Esfandiari, F.1
Villanueva, J.A.2
Wong, D.H.3
-
32
-
-
0035014266
-
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
-
Werstuck GH, Lentz SR, Dayal S, et al. Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest 2001; 107:1263-1273.
-
(2001)
J Clin Invest
, vol.107
, pp. 1263-1273
-
-
Werstuck, G.H.1
Lentz, S.R.2
Dayal, S.3
-
33
-
-
77649205806
-
Endoplasmic reticulum stress involved in the course of lipogenesis in fatty acids-induced hepatic steatosis
-
Liu J, Jin X, Yu CH, et al. Endoplasmic reticulum stress involved in the course of lipogenesis in fatty acids-induced hepatic steatosis. J Gastroenterol Hepatol 2010; 25:613-618.
-
J Gastroenterol Hepatol
, vol.2010
, Issue.25
, pp. 613-618
-
-
Liu, J.1
Jin, X.2
Yu, C.H.3
-
34
-
-
0034515724
-
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
-
Ye J, Rawson RB, Komuro R, et al. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 2000; 6:1355-1364.
-
(2000)
Mol Cell
, vol.6
, pp. 1355-1364
-
-
Ye, J.1
Rawson, R.B.2
Komuro, R.3
-
35
-
-
34548220998
-
Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2
-
Colgan SM,Tang D, Werstuck GH, Austin RC. Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2. Int J Biochem Cell Biol 2007; 39:1843-1851.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 1843-1851
-
-
Colgan Smtang, D.1
Werstuck, G.H.2
Austin, R.C.3
-
36
-
-
7244221504
-
Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1
-
Lee JN, Ye J. Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1. J Biol Chem 2004; 279:45257-45265.
-
(2004)
J Biol Chem
, vol.279
, pp. 45257-45265
-
-
Lee, J.N.1
Ye, J.2
-
37
-
-
69049098806
-
Structural and functional link between the mitochondrial network and the endoplasmic reticulum
-
Giorgi C, De SD, Bononi A, et al. Structural and functional link between the mitochondrial network and the endoplasmic reticulum. Int J Biochem Cell Biol 2009; 41:1817-1827.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1817-1827
-
-
Giorgi, C.1
De Sd Bononi, A.2
-
38
-
-
56949089426
-
Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: A molecular mechanism leading to hepatic insulin resistance
-
Lim JH, Lee HJ, Ho JM, Song J. Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: a molecular mechanism leading to hepatic insulin resistance. Cell Signal 2009; 21:169-177.
-
(2009)
Cell Signal
, vol.21
, pp. 169-177
-
-
Lim, J.H.1
Lee, H.J.2
Ho, J.M.3
Song, J.4
-
39
-
-
0036207720
-
Apolipoprotein synthesis in nonalcoholic steatohepatitis
-
Charlton M, Sreekumar R, Rasmussen D, et al. Apolipoprotein synthesis in nonalcoholic steatohepatitis. Hepatology 2002; 35:898-904.
-
(2002)
Hepatology
, vol.35
, pp. 898-904
-
-
Charlton, M.1
Sreekumar, R.2
Rasmussen, D.3
-
40
-
-
0037382071
-
Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
-
Musso G, Gambino R, De MF, et al. Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology 2003; 37:909-916.
-
(2003)
Hepatology
, vol.37
, pp. 909-916
-
-
Musso, G.1
Gambino, R.2
De, M.F.3
-
41
-
-
0038461088
-
Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis
-
Sreekumar R, Rosado B, Rasmussen D, Charlton M. Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis. Hepatology 2003; 38:244-251.
-
(2003)
Hepatology
, vol.38
, pp. 244-251
-
-
Sreekumar, R.1
Rosado, B.2
Rasmussen, D.3
Charlton, M.4
-
42
-
-
38149136598
-
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents
-
Ota T, Gayet C, Ginsberg HN. Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents. J Clin Invest 2008; 118:316-332.
-
(2008)
J Clin Invest
, vol.118
, pp. 316-332
-
-
Ota, T.1
Gayet, C.2
Ginsberg, H.N.3
-
43
-
-
70350365259
-
Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling
-
Qiu W, Su Q, Rutledge AC, et al. Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling. J Lipid Res 2009; 50:1814-1823.
-
(2009)
J Lipid Res
, vol.50
, pp. 1814-1823
-
-
Qiu, W.1
Su, Q.2
Rutledge, A.C.3
-
44
-
-
67651171781
-
Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance
-
Su Q, Tsai J, Xu E, et al. Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology 2009; 50:77-84.
-
(2009)
Hepatology
, vol.50
, pp. 77-84
-
-
Su, Q.1
Tsai, J.2
Xu, E.3
-
45
-
-
0036217052
-
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
-
Lewis GF, Carpentier A, Adeli K, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 2002; 23:201-229.
-
(2002)
Endocr Rev
, vol.23
, pp. 201-229
-
-
Lewis, G.F.1
Carpentier, A.2
Adeli, K.3
Giacca, A.4
-
46
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
Sanyal AJ, Campbell-Sargent C, Mirshahi F, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001; 120:1183-1192.
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
-
47
-
-
57349110829
-
Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects
-
Sharma NK, Das SK, Mondal AK, et al. Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects. J Clin Endocrinol Metab 2008; 93:4532-4541.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4532-4541
-
-
Sharma, N.K.1
Das, S.K.2
Mondal, A.K.3
-
48
-
-
52749091008
-
Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
-
Boden G, Duan X, Homko C, et al. Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals. Diabetes 2008; 57:2438-2444.
-
(2008)
Diabetes
, vol.57
, pp. 2438-2444
-
-
Boden, G.1
Duan, X.2
Homko, C.3
-
49
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano F, Wang X, Bertolotti A, et al. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 2000; 287:664-666.
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
-
50
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi J, Tuncman G, Chang L, et al. A central role for JNK in obesity and insulin resistance. Nature 2002; 420:333-336.
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
-
51
-
-
65649111766
-
Asymmetrical dimethylarginine triggers lipolysis and inflammatory response via induction of endoplasmic reticulum stress in cultured adipocytes
-
Zhou QG, Zhou M, Hou FF, Peng X. Asymmetrical dimethylarginine triggers lipolysis and inflammatory response via induction of endoplasmic reticulum stress in cultured adipocytes. Am J Physiol Endocrinol Metab 2009; 296:E869-E878.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Zhou, Q.G.1
Zhou, M.2
Hou, F.F.3
Peng, X.4
-
52
-
-
65349113758
-
IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. Elegans
-
Jo H, Shim J, Lee JH, et al. IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Cell Metab 2009; 9:440-448.
-
(2009)
Cell Metab
, vol.9
, pp. 440-448
-
-
Jo, H.1
Shim, J.2
Lee, J.H.3
-
53
-
-
33845575826
-
Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death
-
Borradaile NM, Han X, Harp JD, et al. Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death. J Lipid Res 2006; 47:2726-2737.
-
(2006)
J Lipid Res
, vol.47
, pp. 2726-2737
-
-
Borradaile, N.M.1
Han, X.2
Harp, J.D.3
-
54
-
-
9244231766
-
Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress
-
Kharroubi I, Ladriere L, Cardozo AK, et al. Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress. Endocrinology 2004; 145:5087-5096.
-
(2004)
Endocrinology
, vol.145
, pp. 5087-5096
-
-
Kharroubi, I.1
Ladriere, L.2
Cardozo, A.K.3
-
56
-
-
74049143238
-
Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells
-
Wei Y, Wang D, Gentile CL, Pagliassotti MJ. Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells. Mol Cell Biochem 2009; 331:31-40.
-
(2009)
Mol Cell Biochem
, vol.331
, pp. 31-40
-
-
Wei, Y.1
Wang, D.2
Gentile, C.L.3
Pagliassotti, M.J.4
-
57
-
-
70449730945
-
Serum adipokine levels predictive of liver injury in nonalcoholic fatty liver disease
-
Lemoine M, Ratziu V, Kim M, et al. Serum adipokine levels predictive of liver injury in nonalcoholic fatty liver disease. Liver Int 2009; 29:1431-1438.
-
(2009)
Liver Int
, vol.29
, pp. 1431-1438
-
-
Lemoine, M.1
Ratziu, V.2
Kim, M.3
-
58
-
-
63849339897
-
Could inflammatory markers help diagnose nonalcoholic steatohepatitis?
-
Tarantino G, Conca P, Pasanisi F, et al. Could inflammatory markers help diagnose nonalcoholic steatohepatitis? Eur J Gastroenterol Hepatol 2009; 21:504-511.
-
(2009)
Eur J Gastroenterol Hepatol
, vol.21
, pp. 504-511
-
-
Tarantino, G.1
Conca, P.2
Pasanisi, F.3
-
59
-
-
19944432792
-
Cytokines downregulate the sarcoen-doplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells
-
Cardozo AK, Ortis F, Storling J, et al. Cytokines downregulate the sarcoen-doplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells. Diabetes 2005; 54:452-461.
-
(2005)
Diabetes
, vol.54
, pp. 452-461
-
-
Cardozo, A.K.1
Ortis, F.2
Storling, J.3
-
60
-
-
39149104320
-
The role for endoplasmic reticulum stress in diabetes mellitus
-
Eizirik DL, Cardozo AK, Cnop M. The role for endoplasmic reticulum stress in diabetes mellitus. Endocr Rev 2008; 29:42-61.
-
(2008)
Endocr Rev
, vol.29
, pp. 42-61
-
-
Eizirik, D.L.1
Cardozo, A.K.2
Cnop, M.3
-
61
-
-
0038034358
-
Interferon-gamma induces reactive oxygen species and endoplasmic reticulum stress at the hepatic apoptosis
-
Watanabe Y, Suzuki O, Haruyama T, Akaike T. Interferon-gamma induces reactive oxygen species and endoplasmic reticulum stress at the hepatic apoptosis. J Cell Biochem 2003; 89:244-253.
-
(2003)
J Cell Biochem
, vol.89
, pp. 244-253
-
-
Watanabe, Y.1
Suzuki, O.2
Haruyama, T.3
Akaike, T.4
-
62
-
-
33644873810
-
Hexosamines, insulin resistance, and the complications of diabetes: Current status
-
Buse MG. Hexosamines, insulin resistance, and the complications of diabetes: current status. Am J Physiol Endocrinol Metab 2006; 290:E1-E8.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Buse, M.G.1
-
63
-
-
77349122076
-
Hexosamine biosynthesis pathway (HBP) flux promotes endoplasmic reticulum (ER) stress, lipid accumulation, and inflam matory gene expression in hepatic cells
-
Sage AT, Walter LA, Shi Y, et al. Hexosamine biosynthesis pathway (HBP) flux promotes endoplasmic reticulum (ER) stress, lipid accumulation, and inflam matory gene expression in hepatic cells. Am J Physiol Endocrinol Metab 2009; 298:E499-E511.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Sage, A.T.1
Walter, L.A.2
Shi, Y.3
-
64
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 2006; 313:1137-1140.
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
-
65
-
-
57049111040
-
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcrip-tional master regulators
-
Rutkowski DT, Wu J, Back SH, et al. UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcrip-tional master regulators. Dev Cell 2008; 15:829-840.
-
(2008)
Dev Cell
, vol.15
, pp. 829-840
-
-
Rutkowski, D.T.1
Wu, J.2
Back, S.H.3
-
66
-
-
77949883045
-
Hepatic Bax-inhibitor (BI)-1 inhibits IRE1{alpha} and protects from obesity-associated insulin resistance and glucose intolerance
-
Bailly-Maitre B, Belgardt BF, Jordan SD, et al. Hepatic Bax-inhibitor (BI)-1 inhibits IRE1{alpha} and protects from obesity-associated insulin resistance and glucose intolerance. J Biol Chem 2009; 285:6198-6207.
-
(2009)
J Biol Chem
, vol.285
, pp. 6198-6207
-
-
Bailly-Maitre, B.1
Belgardt, B.F.2
Jordan, S.D.3
|