-
1
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown MS, Goldstein JL: The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89:331-340, 1997
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
2
-
-
0028963743
-
Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain
-
Kim JB, Spotts GD, Halvorsen YD, Shih HM, Ellenberger T, Towle HC, Spiegelman BM: Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Mol Cell Biol 15:2582-2588, 1995
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2582-2588
-
-
Kim, J.B.1
Spotts, G.D.2
Halvorsen, Y.D.3
Shih, H.M.4
Ellenberger, T.5
Towle, H.C.6
Spiegelman, B.M.7
-
3
-
-
0032568557
-
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
-
Horton JD, Bashmakov Y, Shimomura I, Shimano H: Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc Natl Acad Sci U S A 95:5987-5992, 1998
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5987-5992
-
-
Horton, J.D.1
Bashmakov, Y.2
Shimomura, I.3
Shimano, H.4
-
4
-
-
0032933626
-
ADD1/ SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose
-
Foretz M, Pacot C, Dugail I, Lemarchand P, Guichard C, Le Liepvre X, Berthetier-Lubrano C, Spiegelman B, Kim JB, Ferré P, Foufelle F: ADD1/ SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose. Mol Cell Biol 19:3760-3768, 1999
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3760-3768
-
-
Foretz, M.1
Pacot, C.2
Dugail, I.3
Lemarchand, P.4
Guichard, C.5
Le Liepvre, X.6
Berthetier-Lubrano, C.7
Spiegelman, B.8
Kim, J.B.9
Ferré, P.10
Foufelle, F.11
-
5
-
-
0033598749
-
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozolocin-induced diabeles
-
Shimomura I, Bashmakov Y, Ikemoto S, Horton JD, Brown MS, Goldstein JL: Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozolocin-induced diabeles. Proc Natl Acad Sci U S A 96:13656-13661, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 13656-13661
-
-
Shimomura, I.1
Bashmakov, Y.2
Ikemoto, S.3
Horton, J.D.4
Brown, M.S.5
Goldstein, J.L.6
-
6
-
-
0034283596
-
Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes
-
Azzout-Marniche D, Becard D, Guichard C, Foretz M, Ferré P, Foufelle F: Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes. Biochem J 350:389-393, 2000
-
(2000)
Biochem J
, vol.350
, pp. 389-393
-
-
Azzout-Marniche, D.1
Becard, D.2
Guichard, C.3
Foretz, M.4
Ferré, P.5
Foufelle, F.6
-
7
-
-
0029965098
-
SREBP-1 mediates activation of the low density lipoprotein receptor promoter by insulin and insulin-like growth factor-I
-
Streicher R, Kotzka J, Muller-Wieland D, Siemeister G, Munck M, Avci H, Krone W: SREBP-1 mediates activation of the low density lipoprotein receptor promoter by insulin and insulin-like growth factor-I. J Biol Chem 271:7128-7133, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 7128-7133
-
-
Streicher, R.1
Kotzka, J.2
Muller-Wieland, D.3
Siemeister, G.4
Munck, M.5
Avci, H.6
Krone, W.7
-
8
-
-
0031963963
-
Nutritional and insulin regulation of fatty acid synthetase and lieptin gene expression through ADD1/SREBP1
-
Kim JB, Sarraf P, Wright M, Yao KM, Mueller E, Solanes G, Lowell BB, Spiegelman B: Nutritional and insulin regulation of fatty acid synthetase and lieptin gene expression through ADD1/SREBP1. J Clin Invest 101:1-9, 1998
-
(1998)
J Clin Invest
, vol.101
, pp. 1-9
-
-
Kim, J.B.1
Sarraf, P.2
Wright, M.3
Yao, K.M.4
Mueller, E.5
Solanes, G.6
Lowell, B.B.7
Spiegelman, B.8
-
9
-
-
0033607176
-
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
-
Foretz M, Guichard C, Ferré P, Foufelle F: Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci U S A 96:12737-12742, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 12737-12742
-
-
Foretz, M.1
Guichard, C.2
Ferré, P.3
Foufelle, F.4
-
10
-
-
0033430411
-
ADD-1 provides major new insight into the mechanism of insulin action
-
Flier JS, Hollenberg AN: ADD-1 provides major new insight into the mechanism of insulin action. Proc Natl Acad Sci U S A 96:14191-14192, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 14191-14192
-
-
Flier, J.S.1
Hollenberg, A.N.2
-
11
-
-
0023850224
-
Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats
-
Iynedjian PB, Gjinovci A, Renold AE: Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats. J Biol Chem 263:740-744, 1988
-
(1988)
J Biol Chem
, vol.263
, pp. 740-744
-
-
Iynedjian, P.B.1
Gjinovci, A.2
Renold, A.E.3
-
12
-
-
1842384095
-
Rat glucokinase gene: Structure and regulation by insulin
-
Magnuson MA, Andreone TL, Printz RL, Koch S, Granner DK: Rat glucokinase gene: structure and regulation by insulin. Proc Natl Acad Sci U S A 86:4838-4842, 1989
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 4838-4842
-
-
Magnuson, M.A.1
Andreone, T.L.2
Printz, R.L.3
Koch, S.4
Granner, D.K.5
-
13
-
-
0021341428
-
Insulin and glucagon regulate cytosolic phosphoenolpyruvate carboxykinase (GTP) mRNA in rat liver
-
Beale E, Andreone T, Koch S, Granner M, Granner D: Insulin and glucagon regulate cytosolic phosphoenolpyruvate carboxykinase (GTP) mRNA in rat liver. Diabetes 33:328-332, 1984
-
(1984)
Diabetes
, vol.33
, pp. 328-332
-
-
Beale, E.1
Andreone, T.2
Koch, S.3
Granner, M.4
Granner, D.5
-
14
-
-
0028567884
-
Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus
-
Valera A, Pujol A, Pelegrin M, Bosch F: Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci U S A 91:9151-9154, 1994
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 9151-9154
-
-
Valera, A.1
Pujol, A.2
Pelegrin, M.3
Bosch, F.4
-
15
-
-
0029902263
-
Correction of diabetic alterations by glucokinase
-
Ferre T, Pujol A, Riu E, Bosch F, Valera A: Correction of diabetic alterations by glucokinase. Proc Natl Acad Sci U S A 93:7225-7230, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 7225-7230
-
-
Ferre, T.1
Pujol, A.2
Riu, E.3
Bosch, F.4
Valera, A.5
-
16
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B: A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci U S A 95:2509-2514, 1998
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
18
-
-
0014027497
-
The enzymatic carboxylation of phosphoenolpyruvate. 3. Investigation of the kinetics and mechanism of the mitochondrial phosphoenolpyruvate carboxykinase-catalyzed reaction
-
Chang HC, Maruyama H, Miller RS, Lane MD: The enzymatic carboxylation of phosphoenolpyruvate. 3. Investigation of the kinetics and mechanism of the mitochondrial phosphoenolpyruvate carboxykinase-catalyzed reaction. J Biol Chem 241:2421-2430, 1966
-
(1966)
J Biol Chem
, vol.241
, pp. 2421-2430
-
-
Chang, H.C.1
Maruyama, H.2
Miller, R.S.3
Lane, M.D.4
-
19
-
-
0019585554
-
Purification and crystallization of rat liver fatty acid synthetase
-
Linn TC: Purification and crystallization of rat liver fatty acid synthetase. Arch Biochem Biophys 209:613-619, 1981
-
(1981)
Arch Biochem Biophys
, vol.209
, pp. 613-619
-
-
Linn, T.C.1
-
20
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
21
-
-
0025062467
-
Lipogenic enzyme activities and mRNA in rat adipose tissue at weaning
-
Coupe C, Perdereau D, Ferré P, Hitier Y, Narkewicz M, Girard J: Lipogenic enzyme activities and mRNA in rat adipose tissue at weaning. Am J Physiol 258:E126-E133, 1990
-
(1990)
Am J Physiol
, vol.258
-
-
Coupe, C.1
Perdereau, D.2
Ferré, P.3
Hitier, Y.4
Narkewicz, M.5
Girard, J.6
-
22
-
-
0022893665
-
Tissue-specific in vitro transcription from the mouse albumin promoter
-
Gorski K, Carneiro M, Schibler U: Tissue-specific in vitro transcription from the mouse albumin promoter. Cell 47:767-776, 1986
-
(1986)
Cell
, vol.47
, pp. 767-776
-
-
Gorski, K.1
Carneiro, M.2
Schibler, U.3
-
23
-
-
0027409026
-
Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice
-
Herz J, Gerard RD: Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc Natl Acad Sci U S A 90:2812-2816, 1993
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 2812-2816
-
-
Herz, J.1
Gerard, R.D.2
-
24
-
-
0032884829
-
Metabolic impact of glucokinase overexpression in liver: Lowering of blood glucose in fed rats is accompanied by hyperlipirtemia
-
O'Doherty RM, Lehman DL, Telemaque-Potts S, Newgard CB: Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipirtemia. Diabetes 48:2022-2027, 1999
-
(1999)
Diabetes
, vol.48
, pp. 2022-2027
-
-
O'Doherty, R.M.1
Lehman, D.L.2
Telemaque-Potts, S.3
Newgard, C.B.4
-
25
-
-
0034068602
-
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
-
Ferber S, Halkin A, Cohen H, Ber I, Einav Y, Goldberg I, Barshack I, Seijffers R, Kopolovic J, Kaiser N, Karasik A: Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat Med 6:568-572, 2000
-
(2000)
Nat Med
, vol.6
, pp. 568-572
-
-
Ferber, S.1
Halkin, A.2
Cohen, H.3
Ber, I.4
Einav, Y.5
Goldberg, I.6
Barshack, I.7
Seijffers, R.8
Kopolovic, J.9
Kaiser, N.10
Karasik, A.11
-
26
-
-
0033613147
-
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
-
Brown MS, Goldstein JL A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc Natl Acad Sci U S A 96:11041-11048, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11041-11048
-
-
Brown, M.S.1
Goldstein, J.L.2
-
27
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform la in livers of transgenic mice and in cultured cells
-
Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL: Isoform 1c of sterol regulatory element binding protein is less active than isoform la in livers of transgenic mice and in cultured cells. J Clin Invest 99:846-854, 1997
-
(1997)
J Clin Invest
, vol.99
, pp. 846-854
-
-
Shimano, H.1
Horton, J.D.2
Shimomura, I.3
Hammer, R.E.4
Brown, M.S.5
Goldstein, J.L.6
-
28
-
-
0033544940
-
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
-
Shimano H, Yahagi N, Amemiya-Kudo M, Hasty AH, Osuga J, Tamura Y, Shionoiri F, Iizuka Y, Ohashi K, Harada K, Gotoda T, Ishibashi S, Yamada N: Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes. J Biol Chem 274: 35832-358139, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 35832-358139
-
-
Shimano, H.1
Yahagi, N.2
Amemiya-Kudo, M.3
Hasty, A.H.4
Osuga, J.5
Tamura, Y.6
Shionoiri, F.7
Iizuka, Y.8
Ohashi, K.9
Harada, K.10
Gotoda, T.11
Ishibashi, S.12
Yamada, N.13
-
29
-
-
0030007427
-
ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism
-
Kim JB, Spiegelman BM: ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev 10:1096-1107, 1996
-
(1996)
Genes Dev
, vol.10
, pp. 1096-1107
-
-
Kim, J.B.1
Spiegelman, B.M.2
-
30
-
-
0344972105
-
ADD1/SREBP-1c mediates insulin-induced gene expression linked to the MAP kinase pathway
-
Kotzka J, Muller-Wieland D, Koponen A, Njamen D, Kremer L, Roth G, Munck M, Knebel B, Krone W: ADD1/SREBP-1c mediates insulin-induced gene expression linked to the MAP kinase pathway. Biochem Biophys Res Commun 249:375-379, 1998
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 375-379
-
-
Kotzka, J.1
Muller-Wieland, D.2
Koponen, A.3
Njamen, D.4
Kremer, L.5
Roth, G.6
Munck, M.7
Knebel, B.8
Krone, W.9
-
31
-
-
0030884675
-
Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism
-
Niswender KD, Shiota M, Postic C, Cherrington AD, Magnuson MA: Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism. J Biol Chem 272:22570-22575, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 22570-22575
-
-
Niswender, K.D.1
Shiota, M.2
Postic, C.3
Cherrington, A.D.4
Magnuson, M.A.5
-
32
-
-
0029044495
-
Induction of fatty acid synthase gene expression by glucose in primary culture of rat hepatocytes
-
Prip-Buus K, Perdereau D, Foufelle F, Maury J, Ferré P, Girard J: Induction of fatty acid synthase gene expression by glucose in primary culture of rat hepatocytes. Eur J Biochem 230:309-315, 1995
-
(1995)
Eur J Biochem
, vol.230
, pp. 309-315
-
-
Prip-Buus, K.1
Perdereau, D.2
Foufelle, F.3
Maury, J.4
Ferré, P.5
Girard, J.6
-
33
-
-
0032900336
-
Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL
-
Horton JD, Shimano H, Hamilton RL, Brown MS, Goldstein JL: Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL. J Clin Invest 103: 1067-1076, 1999
-
(1999)
J Clin Invest
, vol.103
, pp. 1067-1076
-
-
Horton, J.D.1
Shimano, H.2
Hamilton, R.L.3
Brown, M.S.4
Goldstein, J.L.5
-
34
-
-
0032508718
-
The repression of hormone-activated PEPCK gene expression by glucose is insulin-independent but requires glucose metabolism
-
Scott DK, O'Doherty RM, Stafford JM, Newgard CB, Granner DK: The repression of hormone-activated PEPCK gene expression by glucose is insulin-independent but requires glucose metabolism. J Biol Chem 273: 24145-24151, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 24145-24151
-
-
Scott, D.K.1
O'Doherty, R.M.2
Stafford, J.M.3
Newgard, C.B.4
Granner, D.K.5
-
35
-
-
0032752792
-
The inhibitory effect of glucose on phosphoenolpyruvate carboxykinase gene expression in cultured hepatocytes is transcriptional and requires glucose metabolism
-
Cournarie F, Azzout-Marniche D, Foretz M, Guichard C, Ferré P, Foufelle F: The inhibitory effect of glucose on phosphoenolpyruvate carboxykinase gene expression in cultured hepatocytes is transcriptional and requires glucose metabolism. FEBS Lett 460:527-532, 1999
-
(1999)
FEBS Lett
, vol.460
, pp. 527-532
-
-
Cournarie, F.1
Azzout-Marniche, D.2
Foretz, M.3
Guichard, C.4
Ferré, P.5
Foufelle, F.6
-
36
-
-
0035860743
-
Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription
-
Chakravarty K, Leahy P, Becard D, Hakimi P, Foretz M, Ferre P, Foufelle F, Hanson RW: Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription. J Biol Chem 276:34816-34823, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 34816-34823
-
-
Chakravarty, K.1
Leahy, P.2
Becard, D.3
Hakimi, P.4
Foretz, M.5
Ferre, P.6
Foufelle, F.7
Hanson, R.W.8
-
37
-
-
0021679330
-
Multihormonal regulation of PEPCK gene transcription: The dominant role of insulin
-
Sasaki K, Cripe TP, Koch SR, Andreone TL, Petersen DD, Beale EG, Granner DK: Multihormonal regulation of PEPCK gene transcription: the dominant role of insulin. J Biol Chem 259:15242-15251, 1984
-
(1984)
J Biol Chem
, vol.259
, pp. 15242-15251
-
-
Sasaki, K.1
Cripe, T.P.2
Koch, S.R.3
Andreone, T.L.4
Petersen, D.D.5
Beale, E.G.6
Granner, D.K.7
-
38
-
-
0030829812
-
Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene
-
Shimano H, Shimomura I, Hammer RE, Herz J, Goldstein JL, Brown MS, Horton JD: Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. J Clin Invest 100:2115-2124, 1997
-
(1997)
J Clin Invest
, vol.100
, pp. 2115-2124
-
-
Shimano, H.1
Shimomura, I.2
Hammer, R.E.3
Herz, J.4
Goldstein, J.L.5
Brown, M.S.6
Horton, J.D.7
-
39
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
-
Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL: Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest 98:1575-1584, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 1575-1584
-
-
Shimano, H.1
Horton, J.D.2
Hammer, R.E.3
Shimomura, I.4
Brown, M.S.5
Goldstein, J.L.6
|