Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis

Hepatology

Volumn 38, Issue 1, 2003, Pages 244-251

  Sreekumar, Raghavakaimal ^b   Rosado, Barbara ^b   Rasmussen, Deborah ^b   Charlton, Michael ^a  

^a MAYO CLINIC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE; ALDEHYDE OXIDASE; CATALASE; COMPLEMENT COMPONENT C3; COPPER ZINC SUPEROXIDE DISMUTASE; ELONGATION FACTOR TU; FIBRINOGEN RELATED PROTEIN; GLUCOSE 6 PHOSPHATASE; INSULIN; LONG CHAIN FATTY ACID COENZYME A LIGASE; MESSENGER RNA; METHYLGLUTARYL COENZYME A; OXOACYL COENZYME A THIOLASE; UBIQUITIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; FATTY LIVER; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLUCOSE METABOLISM; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID METABOLISM; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER MITOCHONDRION; MALE; NONALCOHOLIC FATTY LIVER; POLYMERASE CHAIN REACTION; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL;

EID: 0038461088     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2003.50290     Document Type: Article

References (57)

1. Noel M, Hickner J, Ettenhofer T, Gauthier B. The high prevalence of obesity in Michigan primary care practices. An UPRNet study. Upper Peninsula Research Network. J Fam Pract 1998;47:39-43.
2. Harris MI, Flegal KM, Cowie CC, Eberhardt MS, Goldstein DE, Little RR, Wiedmeyer HM, et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994 [see comments]. Diabetes Care 1998;21:518-524.
3. Popkin BM, Udry JR. Adolescent obesity increases significantly in second and third generation U.S. immigrants: the National Longitudinal Study of Adolescent Health. J Nutr 1998;128:701-706.
4. Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL. Overweight and obesity in the United States: prevalence and trends, 1960-1994. Int J Obes Relat Metab Disord 1998;22:39-47.
5. Ludwig J, Viggiano TR, McGill DB, Oh BJ. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980;55:434-438.
6. Marchesini G, Brizi M, Morselli-Labate AM, Bianchi G, Bugianesi E, McCullough AJ, Forlani G, et al. Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 1999;107:450-455.
7. Tankurt E, Biberoglu S, Ellidokuz E, Hekimsoy Z, Akpinar H, Comlekci A, Okan A, et al. Hyperinsulinemia and insulin resistance in non-alcoholic steatohepatitis [letter, comment]. J Hepatol 1999;31:963.
8. Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, Sterling RK, Luketic VA, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities [see comments]. Gastroenterology 2001;120:1183-1192.
9. Cortez-Pinto H, Chatham J, Chacko VP, Arnold C, Rashid A, Diehl AM. Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA 1999;282:1659-1664.
10. Rashid A, Wu TC, Huang CC, Chen CH, Lin HZ, Yang SQ, Lee FY, et al. Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. HEPATOLOGY 1999;29:1131-1138.
11. Yang SQ, Lin HZ, Mandal AK, Huang J, Diehl AM. Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology. HEPATOLOGY 2001;34:694-706.
12. Soltys K, Dikdan G, Koneru B. Oxidative stress in fatty livers of obese Zucker rats: rapid amelioration and improved tolerance to warm ischemia with tocopherol. HEPATOLOGY 2001;34:13-18.
13. Marshall A, Hodgson J. DNA chips: an array of possibilities. Nat Biotechnol 1998;16:27-31.
14. Shackel NA, Gorrell MD, McCaughan GW. Gene array analysis and the liver. HEPATOLOGY 2002;36:1313-1325.
15. Li Y, Sarkar FH. Down-regulation of invasion and angiogenesis-related genes identified by cDNA microarray analysis of PC3 prostate cancer cells treated with genistein. Cancer Lett 2002;186:157-164.
16. Ditt RF, Nester EW, Comai L. Plant gene expression response to Agrobacterium tumefaciens. Proc Natl Acad Sci U S A 2001;98:10954-10959.
17. Pang ST, Dillner K, Wu X, Pousette A, Norstedt G, Flores-Morales A. Gene expression profiling of androgen deficiency predicts a pathway of prostate apoptosis that involves genes related to oxidative stress. Endocrinology 2002;143:4897-4906.
18. Han X, Bolcato AL, Amar S. Identification of genes differentially expressed in cultured human osteoblasts versus human fibroblasts by DNA microarray analysis. Connect Tissue Res 2002;43:63-75.
19. Heishi M, Kagaya S, Katsunuma T, Nakajima T, Yuki K, Akasawa A, Maeda M, et al. High-density oligonucleotide array analysis of mRNA transcripts in peripheral blood cells of severe atopic dermatitis patients. Int Arch Allergy Immunol 2002;129:57-66.
20. McDoniels-Silvers AL, Stoner GD, Lubet RA, You M. Differential expression of critical cellular genes in human lung adenocarcinomas and squamous cell carcinomas in comparison to normal lung tissues. Neoplasia 2002;4:141-150.
21. Liu LX, Jiang HC, Liu ZH, Zhou J, Zhang WH, Zhu AL, Wang XQ, et al. Integrin gene expression profiles of human hepatocellular carcinoma. World J Gastroenterol 2002;8:631-637.
22. Yajima N, Masuda M, Miyazaki M, Nakajima N, Chien S, Shyy JY. Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: a study of the transcription profile with complementary DNA microarray. J Vasc Surg 2002;36:379-385.
23. Mellick AS, Day CJ, Weinstein SR, Griffiths LR, Morrison NA. Differential gene expression in breast cancer cell lines and stroma-tumor differences in microdissected breast cancer biopsies revealed by display array analysis. Int J Cancer 2002;100:172-180.
24. Hartley PS, Bayne RA, Robinson LL, Fulton N, Anderson RA. Developmental changes in expression of myeloid cell leukemia-1 in human germ cells during oogenesis and early folliculogenesis. J Clin Endocrinol Metab 2002;87:3417-3427.
25. Zou TT, Selaru FM, Xu Y, Shustova V, Yin J, Mori Y, Shibata D, et al. Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon. Oncogene 2002;21:4855-4862.
26. Balagopal P, Schimke JC, Ades P, Adey D, Nair KS. Age effect on transcript levels and synthesis rate of muscle MHC and response to resistance exercise. Am J Physiol 2001;280:E203-E208.
27. Hacia JG, Brody LC, Chee MS, Fodor SP, Collins FS. Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis [see comments]. Nat Genet 1996;14:441-447.
28. Lockhart DJ, Dong H, Byrne MC, Follettie MT, Gallo MV, Chee MS, Mittmann M, et al. Expression monitoring by hybridization to high-density oligonucleotide arrays [see comments]. Nat Biotechnol 1996;14:1675-1680.
29. Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, Kiernan TW, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. HEPATOLOGY 1981;1:431-435.
30. Katsuki A, Sumida Y, Gabazza EC, Murashima S, Urakawa H, Morioka K, Kitagawa N, et al. QUICKI is useful for following improvements in insulin sensitivity after therapy in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 2002;87:2906-2908.
31. Mather KJ, Hunt AE, Steinberg HO, Paradisi G, Hook G, Katz A, et al. Repeatability characteristics of simple indices of insulin resistance: implications for research applications. J Clin Endocrinol Metab 2001;86:5457-5464.
32. Ren JG, Xia HL, Just T, Dai YR. Hydroxyl radical-induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation. FEBS Lett 2001;488:123-132.
33. Wallace DC. Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science 1992;256:628-632.
34. Wu J, Karlsson K, Danielsson A. Effects of vitamins E, C and catalase on bromobenzene- and hydrogen peroxide-induced intracellular oxidation and DNA single-strand breakage in Hep G2 cells. J Hepatol 1997;26:669-677.
35. Cohen G, Dembiec D, Marcus J. Measurement of catalase activity in tissue extracts. Anal Biochem 1970;34:30-8-30-38.
36. Kerver ED, Vogels IM, Bosch KS, Vreeling-Sindelarova H, Van den Munckhof RJ, Frederiks WM. In situ detection of spontaneous superoxide anion and singlet oxygen production by mitochondria in rat liver and small intestine. Histochem J 1997;29:229-237.
37. Bondy SC, Orozco J. Effects of ethanol treatment upon sources of reactive oxygen species in brain and liver. Alcohol Alcohol 1994;29:375-383.
38. Karnovsky ML, Badwey JA. Determinants of the production of active oxygen species by granulocytes and macrophages. J Clin Chem Clin Biochem 1983;21:545-553.
39. Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, Sterling RK, Luketic VA, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001;120:1183-1192.
40. Letteron P, Fromenty B, Terris B, Degott C, Pessayre D. Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice. J Hepatol 1996;24:200-208.
41. Macdonald GA, Bridle KR, Ward PJ, Walker NI, Houglum K, George DK, Smith JL, et al. Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3 [erratum appears in J Gastroenterol Hepatol 2001;16:953]. J Gastroenterol Hepatol 2001;16:599-606.
42. Leclercq IA, Farrell GC, Field J, Bell DR, Gonzalez FJ, Robertson GR. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest 2000;105:1067-1075.
43. Dashti N, Ontko JA. Rate-limiting function of 3-hydroxy-3-methylglutaryl-coenzyme A synthase in ketogenesis. Biochem Med 1979;22:365-374.
44. Charlton M, Sreekumar R, Rasmussen D, Lindor K, Nair KS. Apolipoprorein synthesis in nonalcoholic steatohepatitis. HEPATOLOGY 2002;35:898-904.
45. Halliday D, Venkatesan S, Pacy P. Apolipoprotein metabolism: a stableisotope approach. Am J Clin Nutr 1993;57(Suppl):730S.
46. Cryer DR, Matsushima T, Marsh JB, Yudkoff M, Coates PM, Cortner JA. Direct measurement of apolipoprotein B synthesis in human very low density lipoprotein using stable isotopes and mass spectrometry. J Lipid Res 1986;27:508-516.
47. Petrides AS, Groop LC, Riely CA, DeFronzo RA. Effect of physiologic hyperinsulinemia on glucose and lipid metabolism in cirrhosis. J Clin Invest 1991;88:561-570.
48. Lee PD, Jensen MD, Divertie GD, Heiling VJ, Katz HH, Conover CA. Insulin-like growth factor-binding protein-1 response to insulin during suppression of endogenous insulin secretion. Metab Clin Exp 1993;42:409-414.
49. Wu JC, Daughaday WH, Lee SD, Hsiao TS, Chou CK, Lin HD, Tsai YT, et al. Radioimmunoassay of serum IGF-I and IGF-II in patients with chronic liver diseases and hepatocellular carcinoma with or without hypoglycemia. J Lab Clin Med 1988;112:589-594.
50. Mohamed-Ali V, Pinkney JH, Panahloo A, Cwyfan-Hughes S, Holly JM, Yudkin JS. Insulin-like growth factor binding protein-1 in NIDDM: relationship with the insulin resistance syndrome. Clin Endocrinol 1999;50:221-228.
51. Shmueli E, Miell JP, Stewart M, Alberti KG, Record CO. High insulin-like growth factor binding protein 1 levels in cirrhosis: link with insulin resistance. HEPATOLOGY 1996;24:127-133.
52. Shmueli E, Record CO, Alberti KG. Insulin independent glucose uptake in cirrhosis [letter, comment]. HEPATOLOGY 1995;21:265-266.
53. Shmueli E, Stewart M, Alberti KG, Record CO. Growth hormone, insulin-like growth factor-1 and insulin resistance in cirrhosis. HEPATOLOGY 1994;19:322-328.
54. Ahlman B, Charlton M, Fu A, Berg C, O'Brien P, Nair KS. Insulin's effect on synthesis rates of liver proteins. A swine model comparing various precursors of protein synthesis. Diabetes 2001;50:947-954.
55. Meek SE, Persson M, Ford GC, Nair KS. Differential regulation of amino acid exchange and protein dynamics across splanchnic and skeletal muscle beds by insulin in healthy human subjects. Diabetes 1998;47:1824-1835.
56. Sparks JD, Sparks CE. Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes. J Biol Chem 1990;265:8854-8862.
57. Pickup JC, Mattock MB, Chusney GD, Burt D. NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X. Diabetologia 1997;40:1286-1292.