-
1
-
-
0003980480
-
-
Technical Report EPA-600/8-82-007F, U.S. Environmental Protection Agency, Research Triangle Park, NC
-
Baus, D. K., Hsu, R. S., Neal, M. W., Santodonato, J., Sugatt, R. H., Bayard, S., Bayliss, D. L., Hiremath, C. B., and Vaughn-Dellarco, V. (1983) Health Assessment Document for Acrylonitrile. Technical Report EPA-600/8-82-007F, U.S. Environmental Protection Agency, Research Triangle Park, NC.
-
(1983)
Health Assessment Document for Acrylonitrile
-
-
Baus, D.K.1
Hsu, R.S.2
Neal, M.W.3
Santodonato, J.4
Sugatt, R.H.5
Bayard, S.6
Bayliss, D.L.7
Hiremath, C.B.8
Vaughn-Dellarco, V.9
-
2
-
-
0028589882
-
-
International Agency for Research on Cancer, Lyon, France
-
International Agency for Research on Cancer. (1994) IRAC monographs on the evaluation of carcinogenic risks to humans. Vol. 60, Some Industrial Chemicals, pp 389-433, International Agency for Research on Cancer, Lyon, France.
-
(1994)
IRAC Monographs on the Evaluation of Carcinogenic Risks to Humans. Vol. 60, Some Industrial Chemicals
, vol.60
, pp. 389-433
-
-
-
4
-
-
0023849659
-
Acrylamide, its metabolism, developmental and reproductive effects, genotoxicity, and carcinogenicity
-
Dearfield, K. L., Abernathy, C. O., Ottley, M. S., Branter, J. H., and Hayes, P. F. (1988) Acrylamide, its metabolism, developmental and reproductive effects, genotoxicity, and carcinogenicity. Mutat. Res. 195, 45-77.
-
(1988)
Mutat. Res.
, vol.195
, pp. 45-77
-
-
Dearfield, K.L.1
Abernathy, C.O.2
Ottley, M.S.3
Branter, J.H.4
Hayes, P.F.5
-
5
-
-
0003437807
-
-
Princeton Scientific Publishing, Princeton, NJ
-
Maltoni, C., Ciliberti, A., Cotti, G., and Perino, G. (1987) Experimental Research on Acrylonitrile Carcinogenesis, Princeton Scientific Publishing, Princeton, NJ.
-
(1987)
Experimental Research on Acrylonitrile Carcinogenesis
-
-
Maltoni, C.1
Ciliberti, A.2
Cotti, G.3
Perino, G.4
-
6
-
-
0020065985
-
Pharmacokinetics of acrylamide in Fischer-344 rats
-
Miller, M. J., Carter, D. E., and Sipes, I. G. (1982) Pharmacokinetics of acrylamide in Fischer-344 rats. Toxicol. Appl. Pharmacol. 63, 36-64.
-
(1982)
Toxicol. Appl. Pharmacol.
, vol.63
, pp. 36-64
-
-
Miller, M.J.1
Carter, D.E.2
Sipes, I.G.3
-
8
-
-
0030867226
-
Urinary metabolites from F344 rats and B6C3F1 mice coadministered acrylamide and acrylonitrile for 1 or 5 days
-
Sumner, S. C. J., Selvaraj, L., Nauhaus, S. K., and Fennell, T. R. (1997) Urinary metabolites from F344 rats and B6C3F1 mice coadministered acrylamide and acrylonitrile for 1 or 5 days. Chem. Res. Toxicol. 10, 1152-1160.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 1152-1160
-
-
Sumner, S.C.J.1
Selvaraj, L.2
Nauhaus, S.K.3
Fennell, T.R.4
-
10
-
-
0018821675
-
Identification of the major urinary metabolites of acrylonitrile in the rat
-
Langvardt, P. W., Putzig, C. L., Braun, W. H., and Young, J. D. (1980) Identification of the major urinary metabolites of acrylonitrile in the rat. J. Toxicol. Environ. Health 6, 273-282.
-
(1980)
J. Toxicol. Environ. Health
, vol.6
, pp. 273-282
-
-
Langvardt, P.W.1
Putzig, C.L.2
Braun, W.H.3
Young, J.D.4
-
11
-
-
0019449472
-
Formation of mercapturic acids from acrylonitrile, crotononitrile, and cinnamonitrile by direct conjugation and via and epoxide intermediate oxidation process
-
van Bladeren, P. J., Delbressine, L. P. C., Hoogerterp, J. J., Beaumont, A. H. G. M., Briemer, D. D., Seutter-Berlage, F., and van der Gen, A. (1981) Formation of mercapturic acids from acrylonitrile, crotononitrile, and cinnamonitrile by direct conjugation and via and epoxide intermediate oxidation process. Drug Metab. Dispos. 9, 246-249.
-
(1981)
Drug Metab. Dispos.
, vol.9
, pp. 246-249
-
-
Van Bladeren, P.J.1
Delbressine, L.P.C.2
Hoogerterp, J.J.3
Beaumont, A.H.G.M.4
Briemer, D.D.5
Seutter-Berlage, F.6
Van Der Gen, A.7
-
12
-
-
0027258742
-
Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice
-
Kedderris, G. L., Sumner, S. C. J., Held, S. D., Batra, R., Turner, M. J., Jr., Roberts, A. E., and Fennell, T. R. (1993) Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice. Toxicol. Appl. Pharmacol. 120, 288-297.
-
(1993)
Toxicol. Appl. Pharmacol.
, vol.120
, pp. 288-297
-
-
Kedderris, G.L.1
Sumner, S.C.J.2
Held, S.D.3
Batra, R.4
Turner M.J., Jr.5
Roberts, A.E.6
Fennell, T.R.7
-
13
-
-
0027179377
-
Rodent tissue distribution of 2-cyanoethylene oxide, the epoxide metabolite of acrylonitrile
-
Kedderis, G. L., Batra, B., Held, S. D., Loos, M. A., and Teo, S. K. O. (1993) Rodent tissue distribution of 2-cyanoethylene oxide, the epoxide metabolite of acrylonitrile. Toxicol. Lett. 69, 25-30.
-
(1993)
Toxicol. Lett.
, vol.69
, pp. 25-30
-
-
Kedderis, G.L.1
Batra, B.2
Held, S.D.3
Loos, M.A.4
Teo, S.K.O.5
-
14
-
-
0025254653
-
Acrylamide exposure induces an unscheduled DNA synthesis in germ cells of mice that is correlated with the temporal pattern of adduct formation on DNA
-
Sega, G. A., Generoso, E., and Brimer, P. A. (1990) Acrylamide exposure induces an unscheduled DNA synthesis in germ cells of mice that is correlated with the temporal pattern of adduct formation on DNA. Environ. Mol. Mutagen. 16, 137-142.
-
(1990)
Environ. Mol. Mutagen.
, vol.16
, pp. 137-142
-
-
Sega, G.A.1
Generoso, E.2
Brimer, P.A.3
-
16
-
-
0028178839
-
Characterization of phosphodiester adducts produced by the reaction of cyanoethylene oxide with nucleotides
-
Yates, J. M., Fennell, T. R., Turner, M. J., Jr., Recio, L., and Sumner, S. C. J. (1994) Characterization of phosphodiester adducts produced by the reaction of cyanoethylene oxide with nucleotides. Carcinogenesis 16, 277-283.
-
(1994)
Carcinogenesis
, vol.16
, pp. 277-283
-
-
Yates, J.M.1
Fennell, T.R.2
Turner M.J., Jr.3
Recio, L.4
Sumner, S.C.J.5
-
17
-
-
0027323796
-
Characterization of an adduct and its degradation product produced by the reaction of cyanoethylene oxide with deoxythimidine and DNA
-
Yates, J. M., Sumner, S. C. J., Turner, M. J., Jr., Recio, L., and Fennell, T. R. (1993) Characterization of an adduct and its degradation product produced by the reaction of cyanoethylene oxide with deoxythimidine and DNA. Carcinogenesis 14, 1363-1369.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1363-1369
-
-
Yates, J.M.1
Sumner, S.C.J.2
Turner M.J., Jr.3
Recio, L.4
Fennell, T.R.5
-
18
-
-
0024333729
-
DNA adducts of propylene oxide and acrylonitrile epoxide: Hydrolytic deamination of 3-alkyl-dCyd to 3-alkyl-dUrd
-
Solomon, J. J., and Segal, A. (1989) DNA adducts of propylene oxide and acrylonitrile epoxide: hydrolytic deamination of 3-alkyl-dCyd to 3-alkyl-dUrd. Environ. Health Perspect. 81, 19-22.
-
(1989)
Environ. Health Perspect.
, vol.81
, pp. 19-22
-
-
Solomon, J.J.1
Segal, A.2
-
19
-
-
0023731834
-
Mutagenicity of acrylonitrile and its metabolite 2-cyanoethylene oxide in human lymphoblasts in vitro
-
Recio, L., and Skopek, T. (1988) Mutagenicity of acrylonitrile and its metabolite 2-cyanoethylene oxide in human lymphoblasts in vitro. Mutat. Res. 206, 297-305.
-
(1988)
Mutat. Res.
, vol.206
, pp. 297-305
-
-
Recio, L.1
Skopek, T.2
-
20
-
-
0022412486
-
Mutagenicity of acrylamide and its analogues in Salmonella typhimurium
-
Hasimoto, K., and Tanij, H. (1985) Mutagenicity of acrylamide and its analogues in Salmonella typhimurium. Mutat. Res. 158, 129-133.
-
(1985)
Mutat. Res.
, vol.158
, pp. 129-133
-
-
Hasimoto, K.1
Tanij, H.2
-
21
-
-
0011353480
-
The genotoxic activity of acrylamide
-
Barfknecht, T. R., Mecca, D. J., and Naismith, R. W. (1988) The genotoxic activity of acrylamide. Environ. Mol. Mutagen. 11 (Suppl. 11), XXX-XXX.
-
(1988)
Environ. Mol. Mutagen.
, vol.11
, Issue.SUPPL. 11
-
-
Barfknecht, T.R.1
Mecca, D.J.2
Naismith, R.W.3
-
22
-
-
0029903973
-
The metabolism and pharmacokinetics of acrylamide: Implications for mechanisms of toxicity and human risk estimation
-
Calleman, C. J. (1996) The metabolism and pharmacokinetics of acrylamide: Implications for mechanisms of toxicity and human risk estimation. Drug Metab. Rev. 28, 527-590.
-
(1996)
Drug Metab. Rev.
, vol.28
, pp. 527-590
-
-
Calleman, C.J.1
-
23
-
-
0026035519
-
Role of human cytochrome P450-IIE1 in the oxidation of many low molecular weight cancer suspects
-
Guengerich, F. P., Kim, D.-H., and Iwasaki, M. (1991) Role of human cytochrome P450-IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol. 4, 168-179.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 168-179
-
-
Guengerich, F.P.1
Kim, D.-H.2
Iwasaki, M.3
-
24
-
-
0023936245
-
N-Acetyl-S-(1-cyano-2-hydroxyethyl)-L-cysteine, a new urinary metabolite of acrylonitrile and oxiranecarbonitrile
-
Linhart, I., Smejkal, J., and Novak, J. (1988) N-Acetyl-S-(1-cyano-2-hydroxyethyl)-L-cysteine, a new urinary metabolite of acrylonitrile and oxiranecarbonitrile. Arch. Toxicol. 61, 484-488.
-
(1988)
Arch. Toxicol.
, vol.61
, pp. 484-488
-
-
Linhart, I.1
Smejkal, J.2
Novak, J.3
-
25
-
-
0023280198
-
Urinary excretion of acrylonitrile and its metabolites in rats
-
Müller, G., Verkoyen, C., Soton, N., and Norpoth, K. (1987) Urinary excretion of acrylonitrile and its metabolites in rats. Arch. Toxicol. 60, 464-466.
-
(1987)
Arch. Toxicol.
, vol.60
, pp. 464-466
-
-
Müller, G.1
Verkoyen, C.2
Soton, N.3
Norpoth, K.4
-
26
-
-
0027495621
-
Epoxidation of acrylonitrile by rats and human cytochrome P450
-
Kedderris, G. L., Batra, B., and Koop, D. R. (1993) Epoxidation of acrylonitrile by rats and human cytochrome P450. Chem. Res. Toxicol. 6, 866-871.
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 866-871
-
-
Kedderris, G.L.1
Batra, B.2
Koop, D.R.3
-
27
-
-
15844419997
-
Role of CYP2E1 in the hepatotoxicity of acetaminophen
-
Lee, S. S. T., Buters, J. T. M., Pineau, T., Fernandez-Salguero, P., and Gonzalez, F. J. (1996) Role of CYP2E1 in the hepatotoxicity of acetaminophen. J. Biol. Chem. 271, 12063-12067.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12063-12067
-
-
Lee, S.S.T.1
Buters, J.T.M.2
Pineau, T.3
Fernandez-Salguero, P.4
Gonzalez, F.J.5
-
28
-
-
0003633755
-
-
NIH Publication 86-23, National Institutes of Health, Bethesda, MD
-
U.S. Department of Health and Human Services, National Institutes of Health (1985) Guide of the care and use of laboratory animals. NIH Publication 86-23, National Institutes of Health, Bethesda, MD.
-
(1985)
Guide of the Care and Use of Laboratory Animals
-
-
-
29
-
-
77957186623
-
1-Aminobenzotriazole-induced destruction of hepatic and renal cytochromes P450 in male Sprague-Dawley rats
-
Mugford, C. A., Mortillo, M., Mico, B. A., and Tarloff, J. B. (1992) 1-Aminobenzotriazole-induced destruction of hepatic and renal cytochromes P450 in male Sprague-Dawley rats. Fundam. Appl. Toxicol. 19, 43-49.
-
(1992)
Fundam. Appl. Toxicol.
, vol.19
, pp. 43-49
-
-
Mugford, C.A.1
Mortillo, M.2
Mico, B.A.3
Tarloff, J.B.4
-
30
-
-
0014838710
-
Biochemical studies on acrylamide, a neurotoxic agent
-
Hasimoto, K., and Aldridge, W. N. (1970) Biochemical studies on acrylamide, a neurotoxic agent. Biochem. Pharmacol. 19, 2591-2604.
-
(1970)
Biochem. Pharmacol.
, vol.19
, pp. 2591-2604
-
-
Hasimoto, K.1
Aldridge, W.N.2
-
32
-
-
0022550213
-
Acute nephrotoxic potential of acrylonitrile in Fischer F-344 rats
-
Rouisse, L., Chakrabarti, S., and Tuchweber, B. (1986) Acute nephrotoxic potential of acrylonitrile in Fischer F-344 rats. Res. Commun. Chem. Pathol. Pharmacol. 53, 347-360.
-
(1986)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.53
, pp. 347-360
-
-
Rouisse, L.1
Chakrabarti, S.2
Tuchweber, B.3
-
33
-
-
0025601611
-
Effects of inhaled acrylic acid derivatives in rats
-
Vodicka, P., Gut, I., and Frantik, E. (1990) Effects of inhaled acrylic acid derivatives in rats. Toxicology 65, 209-221.
-
(1990)
Toxicology
, vol.65
, pp. 209-221
-
-
Vodicka, P.1
Gut, I.2
Frantik, E.3
-
34
-
-
0032427910
-
Cytochrome P450 and species differences in xenobiotic metabolism and activation of carcinogen
-
Lewis, D. F. V., Loannides, C., and Parke, D. V. (1998) Cytochrome P450 and species differences in xenobiotic metabolism and activation of carcinogen. Environ. Health Perspect. 106, 633-641.
-
(1998)
Environ. Health Perspect.
, vol.106
, pp. 633-641
-
-
Lewis, D.F.V.1
Loannides, C.2
Parke, D.V.3
-
35
-
-
0031885514
-
Cytochrome P450 2E1 polymorphisms in lung cancer in minority populations
-
Wu, X., Amos, C. I., Kemp, B. L., Shi, H., Jiang, H., Wa, Y., and Spitz, M. R. (1998) Cytochrome P450 2E1 polymorphisms in lung cancer in minority populations. Cancer Epidemiol., Biomarkers Prev. 7, 13-18.
-
(1998)
Cancer Epidemiol., Biomarkers Prev.
, vol.7
, pp. 13-18
-
-
Wu, X.1
Amos, C.I.2
Kemp, B.L.3
Shi, H.4
Jiang, H.5
Wa, Y.6
Spitz, M.R.7
-
36
-
-
0030749790
-
CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
-
Hildesheim, A., Anderson, L. M., Chen, C. J., Cheng, Y. J., Brinton, L. A., Daly, A. K., Reed, C. D., Chen, I. H., Caporaso, N. E., Hsu, M. M., Chen, J. Y., Idle, J. R., Hoover, R. N., Yang, C. S., and Chhabra, S. K. (1997) CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan. J. Natl. Cancer Inst. 89, 1207-1212.
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 1207-1212
-
-
Hildesheim, A.1
Anderson, L.M.2
Chen, C.J.3
Cheng, Y.J.4
Brinton, L.A.5
Daly, A.K.6
Reed, C.D.7
Chen, I.H.8
Caporaso, N.E.9
Hsu, M.M.10
Chen, J.Y.11
Idle, J.R.12
Hoover, R.N.13
Yang, C.S.14
Chhabra, S.K.15
-
37
-
-
0032901786
-
The role of cytochrome P450 CYP2E1 in methacrylonitrile metabolism and disposition
-
in press
-
Ghanayem, B. I., Sanders, J. M., Chanas, B., Burka, L. T., and Gonzalez, F. J. (1999) The role of cytochrome P450 CYP2E1 in methacrylonitrile metabolism and disposition. J. Pharmacol. Exp. Toxicol. (in press).
-
(1999)
J. Pharmacol. Exp. Toxicol
-
-
Ghanayem, B.I.1
Sanders, J.M.2
Chanas, B.3
Burka, L.T.4
Gonzalez, F.J.5
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