Association studies of polymorphisms of CYP2E1 gene in alcoholics with cirrhosis, antisocial personality, and normal controls

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 4, 1998, Pages 888-891

  Parsian, Abbas ^a   Cloninger, C Robert ^a   Zhang, Zhen Hua ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cirrhosis; Cytochrome CYP2E1; Haplotype Relative Risk; Polymorphism; Relative Risk

Indexed keywords

ALCOHOL; CYTOCHROME P450; DNA;

ALCOHOL LIVER CIRRHOSIS; ALCOHOLISM; ALLELE; ANTISOCIAL BEHAVIOR; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEMALE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK;

EID: 0031814034     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1998.tb03884.x     Document Type: Article

References (18)

1. Gonzalez FJ: The molecular biology of cytochrome P450s. Pharmacol Rev 40:243-288, 1988
2. Koop DR: Oxidation and reduction metabolism by cytochrome P450IIE1. FASABJ 6:724-730, 1992
3. Takahashi T, Lasker JM, Rosman AS, Lieber CS: Induction of P450IIE1 in human liver by ethanol is due to a corresponding increase in encoding in RNA. Hepatology 17:236-245, 1993
4. Lieber CS: Biochemical and molecular basis of alcohol-induced injury to liver and other tissues. N Engl J Med 319:1639-1650, 1988
5. Hayashi S-I, Watanabe J, Kawajiri K: Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene. J Biochem 110:559-565, 1991
6. Castillo T, Koop DR, Kamimuras, Triadafilopoul G, Tsukamoto H: Role of cytochrome P450IIE1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation. Hepatology 17:564-576, 1993
7. Maezawa Y, Yamauchi M, Toda G: Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to alcoholic liver cirrhosis. Am J Gastroenterol 89:561-565, 1994
8. Iwahashi K, Matzo Y, Suwaki H, Nakamura K, Ishikawa Y: CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese. Alcohol Clin Exp Res 19:564-566, 1995
9. Carr LG, Hartleroad JY, Liang Y, Mendenhall C, Moritz T, Thomasson H: Polymorphism at the P450IIE1 locus is not associated with alcoholic liver disease in Caucasian men. Alcohol Clin Exp Res 19:182-184, 1995
10. Lucas D, Ménez C, Floch F, Gourlaouen Y, Sparfel O, Joannet I, Bodénez P, Jezequel J, Gouérou H, Berthou F, Bardou L-G, Ménez J-F: Cytochromes P450IIE1 and P44501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic Caucasians, Alcohol Clin Exp Res 20:1033-1037, 1996
11. 2 receptor locus: Studies of association and linkage. Arch Gen Psychiatry 48:655-663, 1991
12. Parsian A, Todd RD: Bipolar disorder and the pseudo-autosomal region: An association study. Am J Med Genet 54:5-7, 1994
13. Feighner JP, Robins E, Guze SB, Woodruff AR, Winokur G, Munoz R, et al: Diagnosis criteria for use in psychiatric research. Arch Gen Psychiatry 26:57-63, 1972
14. Cloninger CR: Neurogenetic adaptive mechanisms in alcoholism. Science 236:410-416, 1987
15. Hirvonen A, Husgafvel-Parsianen K, Anttila S, Karjalainen A, Vainio H: The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finnish study population. Carcinogenesis 14:85-88, 1993
16. Roff DA, Bentzen P: The statistical analysis of mitochondrial DNA polymorphisms: Chi-square and the problem of small samples. Biol Evol 6:539-543, 1989
17. Falk CT, Rubinstein P: Haplotype relative risks: An easy reliable way to construct a proper control sample for risk calculation. Ann Hum Genet 51:227-233, 1987
18. 3 receptor gene and bipolar affective disorder. Am J Med Genet 60: 234-237, 1995