Human CYP2E1 mediates the formation of glycidamide from acrylamide

Archives of Toxicology

Volumn 82, Issue 10, 2008, Pages 717-727

  Settels, Eva ^a   Bernauer, Ulrike ^a   Palavinskas, Richard ^a   Klaffke, Horst S ^a   Gundert Remy, Ursula ^a   Appel, Klaus E ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

Acrylamide; Glycidamide; Human CYP2E1; Metabolism; Risk assessment

Indexed keywords

ACRYLAMIDE; CHLORZOXAZONE; CHLORZOXAZONE HYDROXYLASE; CYTOCHROME P450 2E1; DIETHYLDITHIOCARBAMIC ACID; GLYCIDAMIDE; MONOCLONAL ANTIBODY; OXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN V 79; CONTROLLED STUDY; ENZYME ACTIVITY; GAS CHROMATOGRAPHY; GENETIC ENGINEERING; HUMAN; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; TIME;

ACRYLAMIDE; ADULT; ANIMALS; BIOTRANSFORMATION; CALLITHRIX; CARCINOGENS; CELL LINE; CHLORZOXAZONE; CYTOCHROME P-450 CYP2E1; DITIOCARB; ENZYME INHIBITORS; EPOXY COMPOUNDS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROXYLATION; KINETICS; MICROSOMES, LIVER; MIDDLE AGED; RECOMBINANT PROTEINS; RISK ASSESSMENT; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; TRANSFECTION;

ANIMALIA; MARMOSETS; MUS; RODENTIA;

EID: 55049087590     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-008-0296-8     Document Type: Article

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