Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer

Oral Oncology

Volumn 37, Issue 5, 2001, Pages 437-445

  Liu, S ^a   Park, J Y ^b   Schantz, S P ^c   Stern, J C ^d   Lazarus, P ^b  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d NEW YORK EYE AND EAR INFIRMARY   (United States)

Author keywords

CYP2E1; Cytochrome P450; Genetic susceptibility; Oral cancer risk; Polymorphisms

Indexed keywords

CYTOCHROME P450 2E1; TOBACCO SMOKE;

5' UNTRANSLATED REGION; ADULT; AGED; ALLELE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOUTH CARCINOMA; NEGRO; PREVALENCE; PRIORITY JOURNAL; RACE DIFFERENCE; RISK FACTOR; SMOKING; TRANSCRIPTION REGULATION;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; ALLELES; CASE-CONTROL STUDIES; CYTOCHROME P-450 CYP2E1; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; EPIDEMIOLOGIC METHODS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; POLYMORPHISM, GENETIC; RISK FACTORS; SIALYLTRANSFERASES; SMOKING;

EID: 0035016759     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1368-8375(00)00099-3     Document Type: Article

References (44)

1. Food, nutrition and the prevention of cancer: a global perspective. 1997;American Institute for Cancer Research, Washington, D.C.
2. Shimizu M., Lasker J.M., Tsutumi M., Lieber C.S. Immunohistochemical localization of ethanol-inducible P450IIE1 in the rat alimentary tract. Gastroenterology. 99:1990;1044-1053.
3. Farin F.M., Bigler L.G., Oda D., McDougall J.K., Omiecinski C.J. Expression of cytochrome P450 and microsomal epoxide hydrolase in cervical and oral epithelial cells immortalized by human papillomavirus type 16 E6/E7 genes. Carcinogenesis. 16:1995;1391-1401.
4. Lieber C.S. Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev. 77:1997;517-544.
5. Kawajiri K., Nakachi K., Imai K., Yoshii A., Shinoda N., Watanabe J. Identification of genetically high risk individuals to lung cancer by DNA polymorphism of the cytochrome P450 1A1 gene. FEBS Lett. 263:1990;131-133.
6. Hayashi S.-I., Watanabe J., Kawajiiri K. Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytrchrome P450IIE1 gene. J Biochem. 110:1991;559-565.
7. Uematsu F., Kikuchi H., Motomiya M., Abe T., Sagami I., Ohmachi T. Association between restriction fragment length polymorphism of the human cytochrome P450 1A1 gene. Jpn J Cancer Res. 82:1991;254-256.
8. Hecht S.S. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem Res Toxicol. 11:1998;559-603.
9. Kato S., Shields P.G., Caporaso N.E., Hoover R.N., Trump B.F., Sugimura H.et al. Cytochrome P450IIE1 genetic polymorphisms, racial variation, and lung cancer risk. Cancer Res. 52:1992;6712-6715.
10. Stephens E.A., Taylor J.A., Kaplan N., Yang C.H., Hsieh L.L., Lucier G.W.et al. Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese. Pharmacogenetics. 4:1994;185-192.
11. Watanabe J., Hayashi S.i., Kawajiri K. Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5′-flanking region. J Biochem. 116:1994;321-326.
12. Morita S., Yano M., Tsujinaka T., Akiyama Y., Taniguchi M., Kaneko K.et al. Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to head-and-neck squamous-cell carcinoma. Int J Cancer. 80:1999;685-688.
13. Matthias C., Bockmühl U., Jahnke V., Jones P.W., Hayes J.D., Alldersea J.et al. Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: studies in upper aerodigestive tract cancers. Pharmacogenetics. 8:1998;91-100.
14. González M.V., Alvarez V., Pello M.F., Menéndez M.J., Suárez C., Coto E. Genetic polymorphism of N-acetyltransferase-2, glutathione S-transferase-M1, and cytochromes P450IIE1 and P450IID6 in the susceptibility to head and neck cancer. J Clin Pathol. 51:1998;294-298.
15. Lucas D., Ménez C., Floch F., Gourlaouen Y., Sparfel O., Joannet I.et al. Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic Caucasians. Alcohol Clin Exp Res. 20:1996;1033-1037.
16. Hung H.-C., Chuang J., Chien Y.-C., Chern H.-D., Chiang C.-P., Kuo Y.-S Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer. Cancer Epidemiol Biomarkers Prev. 6:1997;901-905.
17. Hildesheim A., Anderson L.M., Chen C.J., Cheng Y.J., Brinton L.A., Daly A.K.et al. CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan. J Nat l Cancer Inst. 89:1997;1207-1212.
18. Benhamou S., Benhamou E., Flamant R. Lung cancer risk associated with cigar and pipe smoking. Int J Cancer. 37:1986;825-829.
19. Park J.Y., Muscat J.E., Ren Q., Schantz S.P., Harwick R.D., Stern J.C.et al. CYP1A1 and GSTM1 polymorphisms and oral cancer risk. Cancer Epidemiol Biomarkers Prev. 6:1997;791-797.
20. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:1997;5463-5467.
21. Maezawa Y., Yamauchi M., Toda G. Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to alcholic liver cirrhosis. Am J Gastroenterol, 89:1994;561-565.
22. Yu M.-W., Gladek-Yarborough A., Chiamprasert S., Santella R.M., Liaw Y.-F., Chen C.-J. Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma. Gastroenterology. 109:1995;1266-1273.
23. Wu X., Shi H., Jiang H., Kemp B., Hong W.K., Delclos G.L.et al. Associations between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer. Carcinogenesis. 18:1997;967-973.
24. Persson I., Johansson I., Bergling H., Dahl M.L., Seidegård J., Rylander R.et al. Genetic polymorphism of cytochrome P4502E1 in a Swedish population. Relationship to incidence of lung cancer. FEBS Lett. 219:1993;207-211.
25. London S.J., Daly A.K., Cooper J., Carpenter C.L., Navidi W.C., Ding L., Idle J.R. Lung cancer risk in relation to the CYP2E1 Rse I genetic polymorphism among African-Americans and Caucasians in Los Angeles County. Pharmacogenetics. 6:1996;151-158.
26. El-Zein R., Conforti-Froes N., Au W.W. Interactions between genetic predisposition and environmental toxicants for development of lung cancer. Environ Mole Mutagen. 30:1997;196-204.
27. Lin D.-X., Tang Y.-M., Peng Q., Lu S.-X., Ambrosone C.B., Kadlubar F.F. Susceptibility to esophageal cancer and genetic polymorphisms in glutathione S-transferases T1, P1, and M1 and cytochrome P450 2E1. Cancer Epidemiol Biomarkers Prev. 7:1998;1013-1018.
28. Le-Marchand L., Sivaraman L., Pierce L., Seifried A., Lum A., Wilkens L.R.et al. Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specifications to tobacco carcinogens. Cancer Res. 58:1998;4858-4863.
29. Wang S.L., Lee H., Chen K-W., Tsai K-J., Chen C-Y., Lin P. Cytochrome P4502E1 genetic polymorphisms and lung cancer in a Taiwanese population. Lung Cancer. 26:1999;27-34.
30. Hamada G.S., Sugimura H., Suzuki I., Nagura K., Kiyokawa E., Iwase T.et al. The heme-binding region polymorphism of cytochrome P450IA1 (CypIA1), rather than the Rsal polymorphism of IIE1 (CypIIE1), is associated with lung cancer in Rio de Janeiro. Cancer Epidemiol Biomarkers Prev. 4:1995;63-67.
31. Watanabe J., Yang J-P., Eguchi H., Hayashi S-i., Imai K., Nakachi K.et al. An Rsa I polymorphism in the CYP2E1 gene does not affect lung cancer risk in a Japanese population. Jpn J Cancer Res. 86:1995;245-248.
32. Hori H., Kawano T., Endo M., Yuasa Y. Genetic polymorphisms of tobacco- and alcohol- related metabolizing enzymes and human esophogeal squamous cell carcinoma susceptibility. J Clin Gastroenterol. 25:1997;568-575.
33. Morita S., Yano M., Shiozaki H., Tsujinaka T., Ebisui C., Morimoto T.et al. CYP1A1, CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous-cell carcinoma of the esophagus. Int J Cancer. 71:1997;192-195.
34. Katoh T., Kaneko S., Kohshi K., Munaka M., Kitagawa K., Kunugita N.et al. Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and oral cavity cancer. Int J Cancer. 83:1999;606-609.
35. Carrière V., Berthou F., Baird S., Belloc C., Beaune P., deWaziers I. Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype. Pharmacogenetics. 6:1996;203-211.
36. Powell H., Kitteringham N.R., Pirmohamed M., Smith D.A., Park B.K. Expression of cytochrome P4502E1 (CYP2E1) in human liver: Assessment on mRNA genotype and phenotype. Pharmacogenetics. 8:1998;411-421.
37. Lucas D., Ménez C., Girre C., Berthou F., Bodénez P., Joannet I.et al. Cytochrome P450 2E1 genotype and chlorzoxazone metabolism in healthy and alcoholic Caucasian subjects. Pharmacogenetics. 5:1995;298-304.
38. Le Marchand L., Wilkinson G.R., Wilkens L.R. Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone. Cancer Epidemiol Biomarkers Prev. 8:1999;495-500.
39. Tsutsumi M., Wang J-S., Takada A. Hepatic messenger RNA contents of cytochrome P4502E1 genotypes. Int Hepatol Commun. 2:1994;135.
40. Tsutsumi M., Wang J-S., Takase S., Takada A. Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes. Alcohol Alcohol. 29:1994;29.
41. Ueshima Y., Tsutsumi M., Takase S., Matsuda Y., Kawahara H. Acetaminophen metabolism in patients with different cytochrome P-450IIE1 genotypes. Alcohol Clin Exp Res. 20:1996;25a.
42. Hu Y., Oscarson M., Johansson I., Yue Q-Y., Dahl M-L., Tabone M.et al. Genetic polymorphism of human CYP2E1, characterization of two variant alleles. Mol Pharmacol. 51:1997;370.
43. Hu Y., Hakkola J., Oscarson M., Ingelman-Sundberg M. Structural and functional characterization of the 5′-flanking region of the rat and human cytochrome P450 2E1 genes: identification of the polymorphic repeat in the human gene. Biochem Biophys Res Commun. 263:1999;286-293.
44. Carr L.G., Hartleroad J.Y., Liang Y., Mendenhall C., Moritz T., Thomasson H. Polymorphism at the P450IIE1 locus is not associated with alcoholic liver disease in Caucasion men. Alcohol Clin Exp Res. 19:1995;182-184.