Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites

Chemico-Biological Interactions

Volumn 166, Issue 1-3, 2007, Pages 132-139

  Kligerman, A D ^a   Hu, Y ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Butadiene; Clastogenicity; Diepoxybutane; DNA damage and repair; Mode of action; Monoepoxybutene; Sister chromatid exchange

Indexed keywords

1,2 EPOXY 3 BUTENE; 1,3 BUTADIENE; BUTADIENE DIEPOXIDE; DNA; DRUG METABOLITE; GLUTATHIONE TRANSFERASE;

AIR POLLUTANT; ARTICLE; CHEMICAL MUTAGENESIS; CHROMOSOME ABERRATION; DNA REPAIR; DNA SYNTHESIS; ENZYME POLYMORPHISM; GENOTOXICITY; HUMAN; LYMPHOCYTE; NONHUMAN; SISTER CHROMATID EXCHANGE;

ANIMALS; BUTADIENES; CELL CYCLE; CELL SEPARATION; CELLS, CULTURED; CHROMOSOME ABERRATIONS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOXY COMPOUNDS; G0 PHASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; LYMPHOCYTES; MICE; MUTAGENS; RATS; SISTER CHROMATID EXCHANGE;

MUS; RATTUS; RODENTIA;

EID: 33947135572     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2006.03.013     Document Type: Article

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