-
1
-
-
33847065486
-
The epigenomics of cancer
-
Jones P.A., and Baylin S.B. The epigenomics of cancer. Cell 128 4 (2007) 683-692
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
2
-
-
33750379420
-
Polycomb silencers control cell fate, development and cancer
-
Sparmann A., and van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 6 11 (2006) 846-856
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.11
, pp. 846-856
-
-
Sparmann, A.1
van Lohuizen, M.2
-
3
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga M.F., Ballestar E., Villar-Garea A., Boix-Chornet M., Espada J., Schotta G., et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37 4 (2005) 391-400
-
(2005)
Nat Genet
, vol.37
, Issue.4
, pp. 391-400
-
-
Fraga, M.F.1
Ballestar, E.2
Villar-Garea, A.3
Boix-Chornet, M.4
Espada, J.5
Schotta, G.6
-
4
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
Weber M., Davies J.J., Wittig D., Oakeley E.J., Haase M., Lam W.L., et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet 37 8 (2005) 853-862
-
(2005)
Nat Genet
, vol.37
, Issue.8
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
Oakeley, E.J.4
Haase, M.5
Lam, W.L.6
-
5
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat Rev Genet 3 6 (2002) 415-428
-
(2002)
Nat Rev Genet
, vol.3
, Issue.6
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
7
-
-
34547914473
-
Unraveling the epigenetic code of cancer for therapy
-
Smith L.T., Otterson G.A., and Plass C. Unraveling the epigenetic code of cancer for therapy. Trends Genet 23 9 (2007) 449-456
-
(2007)
Trends Genet
, vol.23
, Issue.9
, pp. 449-456
-
-
Smith, L.T.1
Otterson, G.A.2
Plass, C.3
-
8
-
-
58149295717
-
Protein arginine methylation in mammals: who, what, and why
-
Bedford M.T., and Clarke S.G. Protein arginine methylation in mammals: who, what, and why. Mol Cell 33 1 (2009) 1-13
-
(2009)
Mol Cell
, vol.33
, Issue.1
, pp. 1-13
-
-
Bedford, M.T.1
Clarke, S.G.2
-
9
-
-
70349335528
-
Mechanisms of transcriptional repression by histone lysine methylation
-
Hublitz P., Albert M., and Peters A.H. Mechanisms of transcriptional repression by histone lysine methylation. Int J Dev Biol 53 2-3 (2009) 335-354
-
(2009)
Int J Dev Biol
, vol.53
, Issue.2-3
, pp. 335-354
-
-
Hublitz, P.1
Albert, M.2
Peters, A.H.3
-
10
-
-
27644589675
-
The diverse functions of histone lysine methylation
-
Martin C., and Zhang Y. The diverse functions of histone lysine methylation. Nat Rev Mol Cell Biol 6 11 (2005) 838-849
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.11
, pp. 838-849
-
-
Martin, C.1
Zhang, Y.2
-
11
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A., Cuddapah S., Cui K., Roh T.Y., Schones D.E., Wang Z., et al. High-resolution profiling of histone methylations in the human genome. Cell 129 4 (2007) 823-837
-
(2007)
Cell
, vol.129
, Issue.4
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
-
12
-
-
44149105533
-
The emerging functions of histone demethylases
-
Agger K., Christensen J., Cloos P.A., and Helin K. The emerging functions of histone demethylases. Curr Opin Genet Dev 18 2 (2008) 159-168
-
(2008)
Curr Opin Genet Dev
, vol.18
, Issue.2
, pp. 159-168
-
-
Agger, K.1
Christensen, J.2
Cloos, P.A.3
Helin, K.4
-
13
-
-
0142105414
-
EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
-
Bracken A.P., Pasini D., Capra M., Prosperini E., Colli E., and Helin K. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J 22 20 (2003) 5323-5335
-
(2003)
EMBO J
, vol.22
, Issue.20
, pp. 5323-5335
-
-
Bracken, A.P.1
Pasini, D.2
Capra, M.3
Prosperini, E.4
Colli, E.5
Helin, K.6
-
14
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally S., Dhanasekaran S.M., Zhou M., Barrette T.R., Kumar-Sinha C., Sanda M.G., et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 419 6907 (2002) 624-629
-
(2002)
Nature
, vol.419
, Issue.6907
, pp. 624-629
-
-
Varambally, S.1
Dhanasekaran, S.M.2
Zhou, M.3
Barrette, T.R.4
Kumar-Sinha, C.5
Sanda, M.G.6
-
15
-
-
33644765912
-
Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer
-
Collett K., Eide G.E., Arnes J., Stefansson I.M., Eide J., Braaten A., et al. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clin Cancer Res 12 4 (2006) 1168-1174
-
(2006)
Clin Cancer Res
, vol.12
, Issue.4
, pp. 1168-1174
-
-
Collett, K.1
Eide, G.E.2
Arnes, J.3
Stefansson, I.M.4
Eide, J.5
Braaten, A.6
-
16
-
-
0141816752
-
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
-
Kleer C.G., Cao Q., Varambally S., Shen R., Ota I., Tomlins S.A., et al. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc Natl Acad Sci USA 100 20 (2003) 11606-11611
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.20
, pp. 11606-11611
-
-
Kleer, C.G.1
Cao, Q.2
Varambally, S.3
Shen, R.4
Ota, I.5
Tomlins, S.A.6
-
17
-
-
29344439946
-
Expression levels of the EZH2 polycomb transcriptional repressor correlate with aggressiveness and invasive potential of bladder carcinomas
-
Weikert S., Christoph F., Kollermann J., Muller M., Schrader M., Miller K., et al. Expression levels of the EZH2 polycomb transcriptional repressor correlate with aggressiveness and invasive potential of bladder carcinomas. Int J Mol Med 16 2 (2005) 349-353
-
(2005)
Int J Mol Med
, vol.16
, Issue.2
, pp. 349-353
-
-
Weikert, S.1
Christoph, F.2
Kollermann, J.3
Muller, M.4
Schrader, M.5
Miller, K.6
-
18
-
-
58949087354
-
MMSET is overexpressed in cancers: link with tumor aggressiveness
-
Kassambara A., Klein B., and Moreaux J. MMSET is overexpressed in cancers: link with tumor aggressiveness. Biochem Biophys Res Commun 379 4 (2009) 840-845
-
(2009)
Biochem Biophys Res Commun
, vol.379
, Issue.4
, pp. 840-845
-
-
Kassambara, A.1
Klein, B.2
Moreaux, J.3
-
19
-
-
12944281108
-
Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis
-
Chadwick R.B., Jiang G.L., Bennington G.A., Yuan B., Johnson C.K., Stevens M.W., et al. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis. Proc Natl Acad Sci USA 97 6 (2000) 2662-2667
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.6
, pp. 2662-2667
-
-
Chadwick, R.B.1
Jiang, G.L.2
Bennington, G.A.3
Yuan, B.4
Johnson, C.K.5
Stevens, M.W.6
-
20
-
-
0035937337
-
Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma
-
Fang W., Piao Z., Buyse I.M., Simon D., Sheu J.C., Perucho M., et al. Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma. Br J Cancer 84 6 (2001) 743-747
-
(2001)
Br J Cancer
, vol.84
, Issue.6
, pp. 743-747
-
-
Fang, W.1
Piao, Z.2
Buyse, I.M.3
Simon, D.4
Sheu, J.C.5
Perucho, M.6
-
21
-
-
33646569453
-
Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas
-
Tam W., Gomez M., Chadburn A., Lee J.W., Chan W.C., and Knowles D.M. Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas. Blood 107 10 (2006) 4090-4100
-
(2006)
Blood
, vol.107
, Issue.10
, pp. 4090-4100
-
-
Tam, W.1
Gomez, M.2
Chadburn, A.3
Lee, J.W.4
Chan, W.C.5
Knowles, D.M.6
-
22
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjoblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., et al. The consensus coding sequences of human breast and colorectal cancers. Science 314 5797 (2006) 268-274
-
(2006)
Science
, vol.314
, Issue.5797
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
-
23
-
-
19444369699
-
Mechanisms predisposing to childhood overgrowth and cancer
-
Rahman N. Mechanisms predisposing to childhood overgrowth and cancer. Curr Opin Genet Dev 15 3 (2005) 227-233
-
(2005)
Curr Opin Genet Dev
, vol.15
, Issue.3
, pp. 227-233
-
-
Rahman, N.1
-
24
-
-
22544456244
-
Genotype-phenotype associations in Sotos syndrome: an analysis of 266 individuals with NSD1 aberrations
-
Tatton-Brown K., Douglas J., Coleman K., Baujat G., Cole T.R., Das S., et al. Genotype-phenotype associations in Sotos syndrome: an analysis of 266 individuals with NSD1 aberrations. Am J Hum Genet 77 2 (2005) 193-204
-
(2005)
Am J Hum Genet
, vol.77
, Issue.2
, pp. 193-204
-
-
Tatton-Brown, K.1
Douglas, J.2
Coleman, K.3
Baujat, G.4
Cole, T.R.5
Das, S.6
-
25
-
-
0037766264
-
Quantitative PCR identifies a minimal deleted region of 120 kb extending from the Philadelphia chromosome ABL translocation breakpoint in chronic myeloid leukemia with poor outcome
-
Kolomietz E., Marrano P., Yee K., Thai B., Braude I., Kolomietz A., et al. Quantitative PCR identifies a minimal deleted region of 120 kb extending from the Philadelphia chromosome ABL translocation breakpoint in chronic myeloid leukemia with poor outcome. Leukemia 17 7 (2003) 1313-1323
-
(2003)
Leukemia
, vol.17
, Issue.7
, pp. 1313-1323
-
-
Kolomietz, E.1
Marrano, P.2
Yee, K.3
Thai, B.4
Braude, I.5
Kolomietz, A.6
-
26
-
-
42549092622
-
Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions
-
Skawran B., Steinemann D., Weigmann A., Flemming P., Becker T., Flik J., et al. Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions. Mod Pathol 21 5 (2008) 505-516
-
(2008)
Mod Pathol
, vol.21
, Issue.5
, pp. 505-516
-
-
Skawran, B.1
Steinemann, D.2
Weigmann, A.3
Flemming, P.4
Becker, T.5
Flik, J.6
-
27
-
-
20244368362
-
Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome
-
Kleefstra T., Smidt M., Banning M.J., Oudakker A.R., Van Esch H., de Brouwer A.P., et al. Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome. J Med Genet 42 4 (2005) 299-306
-
(2005)
J Med Genet
, vol.42
, Issue.4
, pp. 299-306
-
-
Kleefstra, T.1
Smidt, M.2
Banning, M.J.3
Oudakker, A.R.4
Van Esch, H.5
de Brouwer, A.P.6
-
28
-
-
0035872769
-
NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines
-
Angrand P.O., Apiou F., Stewart A.F., Dutrillaux B., Losson R., and Chambon P. NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines. Genomics 74 1 (2001) 79-88
-
(2001)
Genomics
, vol.74
, Issue.1
, pp. 79-88
-
-
Angrand, P.O.1
Apiou, F.2
Stewart, A.F.3
Dutrillaux, B.4
Losson, R.5
Chambon, P.6
-
29
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
Krivtsov A.V., and Armstrong S.A. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 7 11 (2007) 823-833
-
(2007)
Nat Rev Cancer
, vol.7
, Issue.11
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
30
-
-
10744231835
-
Frequency of NUP98-NSD1 fusion transcript in childhood acute myeloid leukaemia
-
Cerveira N., Correia C., Doria S., Bizarro S., Rocha P., Gomes P., et al. Frequency of NUP98-NSD1 fusion transcript in childhood acute myeloid leukaemia. Leukemia 17 11 (2003) 2244-2247
-
(2003)
Leukemia
, vol.17
, Issue.11
, pp. 2244-2247
-
-
Cerveira, N.1
Correia, C.2
Doria, S.3
Bizarro, S.4
Rocha, P.5
Gomes, P.6
-
31
-
-
8444242978
-
Cryptic insertion producing two NUP98/NSD1 chimeric transcripts in adult refractory anemia with an excess of blasts
-
La Starza R., Gorello P., Rosati R., Riezzo A., Veronese A., Ferrazzi E., et al. Cryptic insertion producing two NUP98/NSD1 chimeric transcripts in adult refractory anemia with an excess of blasts. Genes Chromosomes Cancer 41 4 (2004) 395-399
-
(2004)
Genes Chromosomes Cancer
, vol.41
, Issue.4
, pp. 395-399
-
-
La Starza, R.1
Gorello, P.2
Rosati, R.3
Riezzo, A.4
Veronese, A.5
Ferrazzi, E.6
-
32
-
-
0037093259
-
NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15)
-
Rosati R., La Starza R., Veronese A., Aventin A., Schwienbacher C., Vallespi T., et al. NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15). Blood 99 10 (2002) 3857-3860
-
(2002)
Blood
, vol.99
, Issue.10
, pp. 3857-3860
-
-
Rosati, R.1
La Starza, R.2
Veronese, A.3
Aventin, A.4
Schwienbacher, C.5
Vallespi, T.6
-
33
-
-
0032212243
-
The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts
-
Chesi M., Nardini E., Lim R.S., Smith K.D., Kuehl W.M., and Bergsagel P.L. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts. Blood 92 9 (1998) 3025-3034
-
(1998)
Blood
, vol.92
, Issue.9
, pp. 3025-3034
-
-
Chesi, M.1
Nardini, E.2
Lim, R.S.3
Smith, K.D.4
Kuehl, W.M.5
Bergsagel, P.L.6
-
34
-
-
0035890771
-
Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily
-
Du Y., Carling T., Fang W., Piao Z., Sheu J.C., and Huang S. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res 61 22 (2001) 8094-8099
-
(2001)
Cancer Res
, vol.61
, Issue.22
, pp. 8094-8099
-
-
Du, Y.1
Carling, T.2
Fang, W.3
Piao, Z.4
Sheu, J.C.5
Huang, S.6
-
35
-
-
33845564665
-
RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma
-
Lal G., Padmanabha L., Smith B.J., Nicholson R.M., Howe J.R., O'Dorisio M.S., et al. RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma. Cancer 107 12 (2006) 2752-2759
-
(2006)
Cancer
, vol.107
, Issue.12
, pp. 2752-2759
-
-
Lal, G.1
Padmanabha, L.2
Smith, B.J.3
Nicholson, R.M.4
Howe, J.R.5
O'Dorisio, M.S.6
-
36
-
-
54449098519
-
Hyper-methylation of RIZ1 tumor suppressor gene is involved in the early tumorigenesis of hepatocellular carcinoma
-
Piao G.H., Piao W.H., He Y., Zhang H.H., Wang G.Q., and Piao Z. Hyper-methylation of RIZ1 tumor suppressor gene is involved in the early tumorigenesis of hepatocellular carcinoma. Histol Histopathol 23 10 (2008) 1171-1175
-
(2008)
Histol Histopathol
, vol.23
, Issue.10
, pp. 1171-1175
-
-
Piao, G.H.1
Piao, W.H.2
He, Y.3
Zhang, H.H.4
Wang, G.Q.5
Piao, Z.6
-
37
-
-
3042722089
-
PRDM5 is silenced in human cancers and has growth suppressive activities
-
Deng Q., and Huang S. PRDM5 is silenced in human cancers and has growth suppressive activities. Oncogene 23 28 (2004) 4903-4910
-
(2004)
Oncogene
, vol.23
, Issue.28
, pp. 4903-4910
-
-
Deng, Q.1
Huang, S.2
-
38
-
-
34548083307
-
PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer
-
Watanabe Y., Toyota M., Kondo Y., Suzuki H., Imai T., Ohe-Toyota M., et al. PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer. Clin Cancer Res 13 16 (2007) 4786-4794
-
(2007)
Clin Cancer Res
, vol.13
, Issue.16
, pp. 4786-4794
-
-
Watanabe, Y.1
Toyota, M.2
Kondo, Y.3
Suzuki, H.4
Imai, T.5
Ohe-Toyota, M.6
-
39
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
Varambally S., Cao Q., Mani R.S., Shankar S., Wang X., Ateeq B., et al. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 322 5908 (2008) 1695-1699
-
(2008)
Science
, vol.322
, Issue.5908
, pp. 1695-1699
-
-
Varambally, S.1
Cao, Q.2
Mani, R.S.3
Shankar, S.4
Wang, X.5
Ateeq, B.6
-
40
-
-
46749136860
-
MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas
-
Nie K., Gomez M., Landgraf P., Garcia J.F., Liu Y., Tan L.H., et al. MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas. Am J Pathol 173 1 (2008) 242-252
-
(2008)
Am J Pathol
, vol.173
, Issue.1
, pp. 242-252
-
-
Nie, K.1
Gomez, M.2
Landgraf, P.3
Garcia, J.F.4
Liu, Y.5
Tan, L.H.6
-
41
-
-
52049095574
-
Recurrent inactivation of the PRDM1 gene in primary central nervous system lymphoma
-
Courts C., Montesinos-Rongen M., Brunn A., Bug S., Siemer D., Hans V., et al. Recurrent inactivation of the PRDM1 gene in primary central nervous system lymphoma. J Neuropathol Exp Neurol 67 7 (2008) 720-727
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, Issue.7
, pp. 720-727
-
-
Courts, C.1
Montesinos-Rongen, M.2
Brunn, A.3
Bug, S.4
Siemer, D.5
Hans, V.6
-
42
-
-
33344454909
-
Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma
-
Pasqualucci L., Compagno M., Houldsworth J., Monti S., Grunn A., Nandula S.V., et al. Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma. J Exp Med 203 2 (2006) 311-317
-
(2006)
J Exp Med
, vol.203
, Issue.2
, pp. 311-317
-
-
Pasqualucci, L.1
Compagno, M.2
Houldsworth, J.3
Monti, S.4
Grunn, A.5
Nandula, S.V.6
-
43
-
-
67651094142
-
Blimp1 is limiting for transformation in a mouse plasmacytoma model
-
D'Costa K., Emslie D., Metcalf D., Smyth G.K., Karnowski A., Kallies A., et al. Blimp1 is limiting for transformation in a mouse plasmacytoma model. Blood (2009)
-
(2009)
Blood
-
-
D'Costa, K.1
Emslie, D.2
Metcalf, D.3
Smyth, G.K.4
Karnowski, A.5
Kallies, A.6
-
44
-
-
43549087444
-
PRDM1 is involved in chemoresistance of T-cell lymphoma and down-regulated by the proteasome inhibitor
-
Zhao W.L., Liu Y.Y., Zhang Q.L., Wang L., Leboeuf C., Zhang Y.W., et al. PRDM1 is involved in chemoresistance of T-cell lymphoma and down-regulated by the proteasome inhibitor. Blood 111 7 (2008) 3867-3871
-
(2008)
Blood
, vol.111
, Issue.7
, pp. 3867-3871
-
-
Zhao, W.L.1
Liu, Y.Y.2
Zhang, Q.L.3
Wang, L.4
Leboeuf, C.5
Zhang, Y.W.6
-
45
-
-
64749106929
-
Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development
-
Oda H., Okamoto I., Murphy N., Chu J., Price S.M., Shen M.M., et al. Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development. Mol Cell Biol 29 8 (2009) 2278-2295
-
(2009)
Mol Cell Biol
, vol.29
, Issue.8
, pp. 2278-2295
-
-
Oda, H.1
Okamoto, I.2
Murphy, N.3
Chu, J.4
Price, S.M.5
Shen, M.M.6
-
46
-
-
17944380227
-
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
-
Peters A.H., O'Carroll D., Scherthan H., Mechtler K., Sauer S., Schofer C., et al. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107 3 (2001) 323-337
-
(2001)
Cell
, vol.107
, Issue.3
, pp. 323-337
-
-
Peters, A.H.1
O'Carroll, D.2
Scherthan, H.3
Mechtler, K.4
Sauer, S.5
Schofer, C.6
-
47
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet F., Hodgson J.G., Eden A., Jackson-Grusby L., Dausman J., Gray J.W., et al. Induction of tumors in mice by genomic hypomethylation. Science 300 5618 (2003) 489-492
-
(2003)
Science
, vol.300
, Issue.5618
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
Jackson-Grusby, L.4
Dausman, J.5
Gray, J.W.6
-
48
-
-
0032126677
-
Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice
-
Yagi H., Deguchi K., Aono A., Tani Y., Kishimoto T., and Komori T. Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice. Blood 92 1 (1998) 108-117
-
(1998)
Blood
, vol.92
, Issue.1
, pp. 108-117
-
-
Yagi, H.1
Deguchi, K.2
Aono, A.3
Tani, Y.4
Kishimoto, T.5
Komori, T.6
-
49
-
-
0028869112
-
Altered Hox expression and segmental identity in Mll-mutant mice
-
Yu B.D., Hess J.L., Horning S.E., Brown G.A., and Korsmeyer S.J. Altered Hox expression and segmental identity in Mll-mutant mice. Nature 378 6556 (1995) 505-508
-
(1995)
Nature
, vol.378
, Issue.6556
, pp. 505-508
-
-
Yu, B.D.1
Hess, J.L.2
Horning, S.E.3
Brown, G.A.4
Korsmeyer, S.J.5
-
50
-
-
33646230318
-
Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll
-
Terranova R., Agherbi H., Boned A., Meresse S., and Djabali M. Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll. Proc Natl Acad Sci USA 103 17 (2006) 6629-6634
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.17
, pp. 6629-6634
-
-
Terranova, R.1
Agherbi, H.2
Boned, A.3
Meresse, S.4
Djabali, M.5
-
51
-
-
34548413178
-
Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal
-
McMahon K.A., Hiew S.Y., Hadjur S., Veiga-Fernandes H., Menzel U., Price A.J., et al. Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal. Cell Stem Cell 1 3 (2007) 338-345
-
(2007)
Cell Stem Cell
, vol.1
, Issue.3
, pp. 338-345
-
-
McMahon, K.A.1
Hiew, S.Y.2
Hadjur, S.3
Veiga-Fernandes, H.4
Menzel, U.5
Price, A.J.6
-
52
-
-
60149090032
-
Alterations of the CxxC domain preclude oncogenic activation of mixed-lineage leukemia 2
-
Bach C., Mueller D., Buhl S., Garcia-Cuellar M.P., and Slany R.K. Alterations of the CxxC domain preclude oncogenic activation of mixed-lineage leukemia 2. Oncogene 28 6 (2009) 815-823
-
(2009)
Oncogene
, vol.28
, Issue.6
, pp. 815-823
-
-
Bach, C.1
Mueller, D.2
Buhl, S.3
Garcia-Cuellar, M.P.4
Slany, R.K.5
-
53
-
-
0028079924
-
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells
-
Sauvageau G., Lansdorp P.M., Eaves C.J., Hogge D.E., Dragowska W.H., Reid D.S., et al. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc Natl Acad Sci USA 91 25 (1994) 12223-12227
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.25
, pp. 12223-12227
-
-
Sauvageau, G.1
Lansdorp, P.M.2
Eaves, C.J.3
Hogge, D.E.4
Dragowska, W.H.5
Reid, D.S.6
-
54
-
-
0036090290
-
Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion
-
Thorsteinsdottir U., Mamo A., Kroon E., Jerome L., Bijl J., Lawrence H.J., et al. Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood 99 1 (2002) 121-129
-
(2002)
Blood
, vol.99
, Issue.1
, pp. 121-129
-
-
Thorsteinsdottir, U.1
Mamo, A.2
Kroon, E.3
Jerome, L.4
Bijl, J.5
Lawrence, H.J.6
-
55
-
-
59149104026
-
Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias
-
Li Z., Luo R.T., Mi S., Sun M., Chen P., Bao J., et al. Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias. Cancer Res 69 3 (2009) 1109-1116
-
(2009)
Cancer Res
, vol.69
, Issue.3
, pp. 1109-1116
-
-
Li, Z.1
Luo, R.T.2
Mi, S.3
Sun, M.4
Chen, P.5
Bao, J.6
-
56
-
-
0033839641
-
MEIS1 and HOXA7 genes in human acute myeloid leukemia
-
Afonja O., Smith Jr. J.E., Cheng D.M., Goldenberg A.S., Amorosi E., Shimamoto T., et al. MEIS1 and HOXA7 genes in human acute myeloid leukemia. Leuk Res 24 10 (2000) 849-855
-
(2000)
Leuk Res
, vol.24
, Issue.10
, pp. 849-855
-
-
Afonja, O.1
Smith Jr., J.E.2
Cheng, D.M.3
Goldenberg, A.S.4
Amorosi, E.5
Shimamoto, T.6
-
57
-
-
0032715662
-
Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias
-
Lawrence H.J., Rozenfeld S., Cruz C., Matsukuma K., Kwong A., Komuves L., et al. Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias. Leukemia 13 12 (1999) 1993-1999
-
(1999)
Leukemia
, vol.13
, Issue.12
, pp. 1993-1999
-
-
Lawrence, H.J.1
Rozenfeld, S.2
Cruz, C.3
Matsukuma, K.4
Kwong, A.5
Komuves, L.6
-
58
-
-
0041370095
-
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
-
Ayton P.M., and Cleary M.L. Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9. Genes Dev 17 18 (2003) 2298-2307
-
(2003)
Genes Dev
, vol.17
, Issue.18
, pp. 2298-2307
-
-
Ayton, P.M.1
Cleary, M.L.2
-
59
-
-
0032126633
-
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
-
Kroon E., Krosl J., Thorsteinsdottir U., Baban S., Buchberg A.M., and Sauvageau G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J 17 13 (1998) 3714-3725
-
(1998)
EMBO J
, vol.17
, Issue.13
, pp. 3714-3725
-
-
Kroon, E.1
Krosl, J.2
Thorsteinsdottir, U.3
Baban, S.4
Buchberg, A.M.5
Sauvageau, G.6
-
60
-
-
17444375685
-
hDOT1L links histone methylation to leukemogenesis
-
Okada Y., Feng Q., Lin Y., Jiang Q., Li Y., Coffield V.M., et al. hDOT1L links histone methylation to leukemogenesis. Cell 121 2 (2005) 167-178
-
(2005)
Cell
, vol.121
, Issue.2
, pp. 167-178
-
-
Okada, Y.1
Feng, Q.2
Lin, Y.3
Jiang, Q.4
Li, Y.5
Coffield, V.M.6
-
61
-
-
33748207226
-
Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L
-
Okada Y., Jiang Q., Lemieux M., Jeannotte L., Su L., and Zhang Y. Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L. Nat Cell Biol 8 9 (2006) 1017-1024
-
(2006)
Nat Cell Biol
, vol.8
, Issue.9
, pp. 1017-1024
-
-
Okada, Y.1
Jiang, Q.2
Lemieux, M.3
Jeannotte, L.4
Su, L.5
Zhang, Y.6
-
62
-
-
0032807691
-
Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic
-
Tebar F., Bohlander S.K., and Sorkin A. Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic. Mol Biol Cell 10 8 (1999) 2687-2702
-
(1999)
Mol Biol Cell
, vol.10
, Issue.8
, pp. 2687-2702
-
-
Tebar, F.1
Bohlander, S.K.2
Sorkin, A.3
-
63
-
-
70149123507
-
Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10 positive leukemias
-
Lin Y.H., Kakadia P.M., Chen Y., Li Y.Q., Deshpande A.J., Buske C., et al. Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10 positive leukemias. Blood (2009)
-
(2009)
Blood
-
-
Lin, Y.H.1
Kakadia, P.M.2
Chen, Y.3
Li, Y.Q.4
Deshpande, A.J.5
Buske, C.6
-
64
-
-
34548565789
-
Expression of a CALM-AF10 fusion gene leads to Hoxa cluster overexpression and acute leukemia in transgenic mice
-
Caudell D., Zhang Z., Chung Y.J., and Aplan P.D. Expression of a CALM-AF10 fusion gene leads to Hoxa cluster overexpression and acute leukemia in transgenic mice. Cancer Res 67 17 (2007) 8022-8031
-
(2007)
Cancer Res
, vol.67
, Issue.17
, pp. 8022-8031
-
-
Caudell, D.1
Zhang, Z.2
Chung, Y.J.3
Aplan, P.D.4
-
65
-
-
54549083228
-
H3K79 methylation profiles define murine and human MLL-AF4 leukemias
-
Krivtsov A.V., Feng Z., Lemieux M.E., Faber J., Vempati S., Sinha A.U., et al. H3K79 methylation profiles define murine and human MLL-AF4 leukemias. Cancer Cell 14 5 (2008) 355-368
-
(2008)
Cancer Cell
, vol.14
, Issue.5
, pp. 355-368
-
-
Krivtsov, A.V.1
Feng, Z.2
Lemieux, M.E.3
Faber, J.4
Vempati, S.5
Sinha, A.U.6
-
66
-
-
39649084473
-
A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification
-
Mueller D., Bach C., Zeisig D., Garcia-Cuellar M.P., Monroe S., Sreekumar A., et al. A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification. Blood 110 13 (2007) 4445-4454
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4445-4454
-
-
Mueller, D.1
Bach, C.2
Zeisig, D.3
Garcia-Cuellar, M.P.4
Monroe, S.5
Sreekumar, A.6
-
67
-
-
24644514410
-
The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin
-
Zeisig D.T., Bittner C.B., Zeisig B.B., Garcia-Cuellar M.P., Hess J.L., and Slany R.K. The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin. Oncogene 24 35 (2005) 5525-5532
-
(2005)
Oncogene
, vol.24
, Issue.35
, pp. 5525-5532
-
-
Zeisig, D.T.1
Bittner, C.B.2
Zeisig, B.B.3
Garcia-Cuellar, M.P.4
Hess, J.L.5
Slany, R.K.6
-
68
-
-
34347392874
-
NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
-
Wang G.G., Cai L., Pasillas M.P., and Kamps M.P. NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis. Nat Cell Biol 9 7 (2007) 804-812
-
(2007)
Nat Cell Biol
, vol.9
, Issue.7
, pp. 804-812
-
-
Wang, G.G.1
Cai, L.2
Pasillas, M.P.3
Kamps, M.P.4
-
69
-
-
67349266612
-
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger
-
Wang G.G., Song J., Wang Z., Dormann H.L., Casadio F., Li H., et al. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature (2009)
-
(2009)
Nature
-
-
Wang, G.G.1
Song, J.2
Wang, Z.3
Dormann, H.L.4
Casadio, F.5
Li, H.6
-
70
-
-
34848865728
-
Protein arginine-methyltransferase-dependent oncogenesis
-
Cheung N., Chan L.C., Thompson A., Cleary M.L., and So C.W. Protein arginine-methyltransferase-dependent oncogenesis. Nat Cell Biol 9 10 (2007) 1208-1215
-
(2007)
Nat Cell Biol
, vol.9
, Issue.10
, pp. 1208-1215
-
-
Cheung, N.1
Chan, L.C.2
Thompson, A.3
Cleary, M.L.4
So, C.W.5
-
71
-
-
22044452929
-
The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy
-
Whitman S.P., Liu S., Vukosavljevic T., Rush L.J., Yu L., Liu C., et al. The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy. Blood 106 1 (2005) 345-352
-
(2005)
Blood
, vol.106
, Issue.1
, pp. 345-352
-
-
Whitman, S.P.1
Liu, S.2
Vukosavljevic, T.3
Rush, L.J.4
Yu, L.5
Liu, C.6
-
72
-
-
55249114697
-
The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele
-
Dorrance A.M., Liu S., Chong A., Pulley B., Nemer D., Guimond M., et al. The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele. Blood 112 6 (2008) 2508-2511
-
(2008)
Blood
, vol.112
, Issue.6
, pp. 2508-2511
-
-
Dorrance, A.M.1
Liu, S.2
Chong, A.3
Pulley, B.4
Nemer, D.5
Guimond, M.6
-
73
-
-
33749424957
-
Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations
-
Dorrance A.M., Liu S., Yuan W., Becknell B., Arnoczky K.J., Guimond M., et al. Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. J Clin Invest 116 10 (2006) 2707-2716
-
(2006)
J Clin Invest
, vol.116
, Issue.10
, pp. 2707-2716
-
-
Dorrance, A.M.1
Liu, S.2
Yuan, W.3
Becknell, B.4
Arnoczky, K.J.5
Guimond, M.6
-
74
-
-
43249102851
-
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
-
Cloos P.A., Christensen J., Agger K., and Helin K. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev 22 9 (2008) 1115-1140
-
(2008)
Genes Dev
, vol.22
, Issue.9
, pp. 1115-1140
-
-
Cloos, P.A.1
Christensen, J.2
Agger, K.3
Helin, K.4
-
75
-
-
0037979272
-
Methylation of histone H3 by Set2 in Saccharomyces cerevisae is linked to transcriptional elongation by RNA polymerase II
-
Krogan N.J., Kim M., Tong A., Golshani A., Cagney G., Canadien V., et al. Methylation of histone H3 by Set2 in Saccharomyces cerevisae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol 23 12 (2003) 4207-4218
-
(2003)
Mol Cell Biol
, vol.23
, Issue.12
, pp. 4207-4218
-
-
Krogan, N.J.1
Kim, M.2
Tong, A.3
Golshani, A.4
Cagney, G.5
Canadien, V.6
-
76
-
-
0037512273
-
The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II
-
Li B., Howe L., Anderson S., Yates III J.R., and Workman J.L. The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem 278 11 (2003) 8897-8903
-
(2003)
J Biol Chem
, vol.278
, Issue.11
, pp. 8897-8903
-
-
Li, B.1
Howe, L.2
Anderson, S.3
Yates III, J.R.4
Workman, J.L.5
-
77
-
-
0036170767
-
Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression
-
Strahl B.D., Grant P.A., Briggs S.D., Sun Z.W., Bone J.R., Caldwell J.A., et al. Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol 22 5 (2002) 1298-1306
-
(2002)
Mol Cell Biol
, vol.22
, Issue.5
, pp. 1298-1306
-
-
Strahl, B.D.1
Grant, P.A.2
Briggs, S.D.3
Sun, Z.W.4
Bone, J.R.5
Caldwell, J.A.6
-
78
-
-
0037336041
-
Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast
-
Xiao T., Hall H., Kizer K.O., Shibata Y., Hall M.C., Borchers C.H., et al. Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast. Genes Dev 17 5 (2003) 654-663
-
(2003)
Genes Dev
, vol.17
, Issue.5
, pp. 654-663
-
-
Xiao, T.1
Hall, H.2
Kizer, K.O.3
Shibata, Y.4
Hall, M.C.5
Borchers, C.H.6
-
79
-
-
67650461956
-
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome
-
Nimura K., Ura K., Shiratori H., Ikawa M., Okabe M., Schwartz R.J., et al. A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature 460 7252 (2009) 287-291
-
(2009)
Nature
, vol.460
, Issue.7252
, pp. 287-291
-
-
Nimura, K.1
Ura, K.2
Shiratori, H.3
Ikawa, M.4
Okabe, M.5
Schwartz, R.J.6
-
80
-
-
0037599617
-
NSD1 is essential for early post-implantation development and has a catalytically active SET domain
-
Rayasam G.V., Wendling O., Angrand P.O., Mark M., Niederreither K., Song L., et al. NSD1 is essential for early post-implantation development and has a catalytically active SET domain. EMBO J 22 12 (2003) 3153-3163
-
(2003)
EMBO J
, vol.22
, Issue.12
, pp. 3153-3163
-
-
Rayasam, G.V.1
Wendling, O.2
Angrand, P.O.3
Mark, M.4
Niederreither, K.5
Song, L.6
-
81
-
-
0032526951
-
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators
-
Huang N., vom Baur E., Garnier J.M., Lerouge T., Vonesch J.L., Lutz Y., et al. Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO J 17 12 (1998) 3398-3412
-
(1998)
EMBO J
, vol.17
, Issue.12
, pp. 3398-3412
-
-
Huang, N.1
vom Baur, E.2
Garnier, J.M.3
Lerouge, T.4
Vonesch, J.L.5
Lutz, Y.6
-
82
-
-
0035883090
-
A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15. 5) in de novo childhood acute myeloid leukemia
-
Jaju R.J., Fidler C., Haas O.A., Strickson A.J., Watkins F., Clark K., et al. A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15. 5) in de novo childhood acute myeloid leukemia. Blood 98 4 (2001) 1264-1267
-
(2001)
Blood
, vol.98
, Issue.4
, pp. 1264-1267
-
-
Jaju, R.J.1
Fidler, C.2
Haas, O.A.3
Strickson, A.J.4
Watkins, F.5
Clark, K.6
-
83
-
-
18544384537
-
Haploinsufficiency of NSD1 causes Sotos syndrome
-
Kurotaki N., Imaizumi K., Harada N., Masuno M., Kondoh T., Nagai T., et al. Haploinsufficiency of NSD1 causes Sotos syndrome. Nat Genet 30 4 (2002) 365-366
-
(2002)
Nat Genet
, vol.30
, Issue.4
, pp. 365-366
-
-
Kurotaki, N.1
Imaizumi, K.2
Harada, N.3
Masuno, M.4
Kondoh, T.5
Nagai, T.6
-
84
-
-
20844463416
-
Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients
-
Keats J.J., Maxwell C.A., Taylor B.J., Hendzel M.J., Chesi M., Bergsagel P.L., et al. Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients. Blood 105 10 (2005) 4060-4069
-
(2005)
Blood
, vol.105
, Issue.10
, pp. 4060-4069
-
-
Keats, J.J.1
Maxwell, C.A.2
Taylor, B.J.3
Hendzel, M.J.4
Chesi, M.5
Bergsagel, P.L.6
-
85
-
-
0036721371
-
Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy
-
Moreau P., Facon T., Leleu X., Morineau N., Huyghe P., Harousseau J.L., et al. Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy. Blood 100 5 (2002) 1579-1583
-
(2002)
Blood
, vol.100
, Issue.5
, pp. 1579-1583
-
-
Moreau, P.1
Facon, T.2
Leleu, X.3
Morineau, N.4
Huyghe, P.5
Harousseau, J.L.6
-
86
-
-
0037443417
-
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript
-
Santra M., Zhan F., Tian E., Barlogie B., and Shaughnessy Jr. J. A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript. Blood 101 6 (2003) 2374-2376
-
(2003)
Blood
, vol.101
, Issue.6
, pp. 2374-2376
-
-
Santra, M.1
Zhan, F.2
Tian, E.3
Barlogie, B.4
Shaughnessy Jr., J.5
-
87
-
-
0031779421
-
WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma
-
Stec I., Wright T.J., van Ommen G.J., de Boer P.A., van Haeringen A., Moorman A.F., et al. WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma. Hum Mol Genet 7 7 (1998) 1071-1082
-
(1998)
Hum Mol Genet
, vol.7
, Issue.7
, pp. 1071-1082
-
-
Stec, I.1
Wright, T.J.2
van Ommen, G.J.3
de Boer, P.A.4
van Haeringen, A.5
Moorman, A.F.6
-
88
-
-
38349087546
-
The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity
-
Lauring J., Abukhdeir A.M., Konishi H., Garay J.P., Gustin J.P., Wang Q., et al. The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity. Blood 111 2 (2008) 856-864
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 856-864
-
-
Lauring, J.1
Abukhdeir, A.M.2
Konishi, H.3
Garay, J.P.4
Gustin, J.P.5
Wang, Q.6
-
89
-
-
42449161943
-
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor
-
Marango J., Shimoyama M., Nishio H., Meyer J.A., Min D.J., Sirulnik A., et al. The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood 111 6 (2008) 3145-3154
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3145-3154
-
-
Marango, J.1
Shimoyama, M.2
Nishio, H.3
Meyer, J.A.4
Min, D.J.5
Sirulnik, A.6
-
90
-
-
58149232433
-
MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells
-
Brito J.L., Walker B., Jenner M., Dickens N.J., Brown N.J., Ross F.M., et al. MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells. Haematologica 94 1 (2009) 78-86
-
(2009)
Haematologica
, vol.94
, Issue.1
, pp. 78-86
-
-
Brito, J.L.1
Walker, B.2
Jenner, M.3
Dickens, N.J.4
Brown, N.J.5
Ross, F.M.6
-
91
-
-
40349098063
-
Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity
-
Kim J.Y., Kee H.J., Choe N.W., Kim S.M., Eom G.H., Baek H.J., et al. Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity. Mol Cell Biol 28 6 (2008) 2023-2034
-
(2008)
Mol Cell Biol
, vol.28
, Issue.6
, pp. 2023-2034
-
-
Kim, J.Y.1
Kee, H.J.2
Choe, N.W.3
Kim, S.M.4
Eom, G.H.5
Baek, H.J.6
-
92
-
-
64549161949
-
NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11;p15) and expression pattern of NSD family genes
-
Taketani T., Taki T., Nakamura H., Taniwaki M., Masuda J., and Hayashi Y. NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11;p15) and expression pattern of NSD family genes. Cancer Genet Cytogenet 190 2 (2009) 108-112
-
(2009)
Cancer Genet Cytogenet
, vol.190
, Issue.2
, pp. 108-112
-
-
Taketani, T.1
Taki, T.2
Nakamura, H.3
Taniwaki, M.4
Masuda, J.5
Hayashi, Y.6
-
93
-
-
8844265508
-
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
-
Ringrose L., and Paro R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet 38 (2004) 413-443
-
(2004)
Annu Rev Genet
, vol.38
, pp. 413-443
-
-
Ringrose, L.1
Paro, R.2
-
94
-
-
4344666089
-
Division of labor in polycomb group repression
-
Levine S.S., King I.F., and Kingston R.E. Division of labor in polycomb group repression. Trends Biochem Sci 29 9 (2004) 478-485
-
(2004)
Trends Biochem Sci
, vol.29
, Issue.9
, pp. 478-485
-
-
Levine, S.S.1
King, I.F.2
Kingston, R.E.3
-
95
-
-
33644822360
-
EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
-
Bachmann I.M., Halvorsen O.J., Collett K., Stefansson I.M., Straume O., Haukaas S.A., et al. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J Clin Oncol 24 2 (2006) 268-273
-
(2006)
J Clin Oncol
, vol.24
, Issue.2
, pp. 268-273
-
-
Bachmann, I.M.1
Halvorsen, O.J.2
Collett, K.3
Stefansson, I.M.4
Straume, O.5
Haukaas, S.A.6
-
96
-
-
14344280487
-
Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors
-
Koontz J.I., Soreng A.L., Nucci M., Kuo F.C., Pauwels P., van Den Berghe H., et al. Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors. Proc Natl Acad Sci USA 98 11 (2001) 6348-6353
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.11
, pp. 6348-6353
-
-
Koontz, J.I.1
Soreng, A.L.2
Nucci, M.3
Kuo, F.C.4
Pauwels, P.5
van Den Berghe, H.6
-
97
-
-
38049134281
-
Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival
-
Li H., Ma X., Wang J., Koontz J., Nucci M., and Sklar J. Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival. Proc Natl Acad Sci USA 104 50 (2007) 20001-20006
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.50
, pp. 20001-20006
-
-
Li, H.1
Ma, X.2
Wang, J.3
Koontz, J.4
Nucci, M.5
Sklar, J.6
-
98
-
-
67349203626
-
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
-
van Haaften G., Dalgliesh G.L., Davies H., Chen L., Bignell G., Greenman C., et al. Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nat Genet 41 5 (2009) 521-523
-
(2009)
Nat Genet
, vol.41
, Issue.5
, pp. 521-523
-
-
van Haaften, G.1
Dalgliesh, G.L.2
Davies, H.3
Chen, L.4
Bignell, G.5
Greenman, C.6
-
99
-
-
65549083102
-
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2
-
Friedman J.M., Liang G., Liu C.C., Wolff E.M., Tsai Y.C., Ye W., et al. The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Res 69 6 (2009) 2623-2629
-
(2009)
Cancer Res
, vol.69
, Issue.6
, pp. 2623-2629
-
-
Friedman, J.M.1
Liang, G.2
Liu, C.C.3
Wolff, E.M.4
Tsai, Y.C.5
Ye, W.6
-
100
-
-
61349112251
-
MYC stimulates EZH2 expression by repression of its negative regulator miR-26a
-
Sander S., Bullinger L., Klapproth K., Fiedler K., Kestler H.A., Barth T.F., et al. MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood 112 10 (2008) 4202-4212
-
(2008)
Blood
, vol.112
, Issue.10
, pp. 4202-4212
-
-
Sander, S.1
Bullinger, L.2
Klapproth, K.3
Fiedler, K.4
Kestler, H.A.5
Barth, T.F.6
-
101
-
-
30544454697
-
The polycomb group protein enhancer of zeste homolog 2 (EZH 2) is an oncogene that influences myeloma cell growth and the mutant ras phenotype
-
Croonquist P.A., and Van Ness B. The polycomb group protein enhancer of zeste homolog 2 (EZH 2) is an oncogene that influences myeloma cell growth and the mutant ras phenotype. Oncogene 24 41 (2005) 6269-6280
-
(2005)
Oncogene
, vol.24
, Issue.41
, pp. 6269-6280
-
-
Croonquist, P.A.1
Van Ness, B.2
-
102
-
-
33747587608
-
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all
-
Gil J., and Peters G. Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. Nat Rev Mol Cell Biol 7 9 (2006) 667-677
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.9
, pp. 667-677
-
-
Gil, J.1
Peters, G.2
-
103
-
-
33947134834
-
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
-
Bracken A.P., Kleine-Kohlbrecher D., Dietrich N., Pasini D., Gargiulo G., Beekman C., et al. The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev 21 5 (2007) 525-530
-
(2007)
Genes Dev
, vol.21
, Issue.5
, pp. 525-530
-
-
Bracken, A.P.1
Kleine-Kohlbrecher, D.2
Dietrich, N.3
Pasini, D.4
Gargiulo, G.5
Beekman, C.6
-
104
-
-
0025727771
-
Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice
-
Haupt Y., Alexander W.S., Barri G., Klinken S.P., and Adams J.M. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Cell 65 5 (1991) 753-763
-
(1991)
Cell
, vol.65
, Issue.5
, pp. 753-763
-
-
Haupt, Y.1
Alexander, W.S.2
Barri, G.3
Klinken, S.P.4
Adams, J.M.5
-
105
-
-
0025863346
-
Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging
-
van Lohuizen M., Verbeek S., Scheijen B., Wientjens E., van der Gulden H., and Berns A. Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging. Cell 65 5 (1991) 737-752
-
(1991)
Cell
, vol.65
, Issue.5
, pp. 737-752
-
-
van Lohuizen, M.1
Verbeek, S.2
Scheijen, B.3
Wientjens, E.4
van der Gulden, H.5
Berns, A.6
-
106
-
-
0033569429
-
Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF
-
Jacobs J.J., Scheijen B., Voncken J.W., Kieboom K., Berns A., and van Lohuizen M. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. Genes Dev 13 20 (1999) 2678-2690
-
(1999)
Genes Dev
, vol.13
, Issue.20
, pp. 2678-2690
-
-
Jacobs, J.J.1
Scheijen, B.2
Voncken, J.W.3
Kieboom, K.4
Berns, A.5
van Lohuizen, M.6
-
107
-
-
20544453888
-
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice
-
Bruggeman S.W., Valk-Lingbeek M.E., van der Stoop P.P., Jacobs J.J., Kieboom K., Tanger E., et al. Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice. Genes Dev 19 12 (2005) 1438-1443
-
(2005)
Genes Dev
, vol.19
, Issue.12
, pp. 1438-1443
-
-
Bruggeman, S.W.1
Valk-Lingbeek, M.E.2
van der Stoop, P.P.3
Jacobs, J.J.4
Kieboom, K.5
Tanger, E.6
-
108
-
-
0028201742
-
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene
-
van der Lugt N.M., Domen J., Linders K., van Roon M., Robanus-Maandag E., te Riele H., et al. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. Genes Dev 8 7 (1994) 757-769
-
(1994)
Genes Dev
, vol.8
, Issue.7
, pp. 757-769
-
-
van der Lugt, N.M.1
Domen, J.2
Linders, K.3
van Roon, M.4
Robanus-Maandag, E.5
te Riele, H.6
-
109
-
-
22344449361
-
Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
-
Molofsky A.V., He S., Bydon M., Morrison S.J., and Pardal R. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev 19 12 (2005) 1432-1437
-
(2005)
Genes Dev
, vol.19
, Issue.12
, pp. 1432-1437
-
-
Molofsky, A.V.1
He, S.2
Bydon, M.3
Morrison, S.J.4
Pardal, R.5
-
110
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky A.V., Pardal R., Iwashita T., Park I.K., Clarke M.F., and Morrison S.J. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425 6961 (2003) 962-967
-
(2003)
Nature
, vol.425
, Issue.6961
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.K.4
Clarke, M.F.5
Morrison, S.J.6
-
111
-
-
33947576177
-
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus
-
Dietrich N., Bracken A.P., Trinh E., Schjerling C.K., Koseki H., Rappsilber J., et al. Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus. EMBO J 26 6 (2007) 1637-1648
-
(2007)
EMBO J
, vol.26
, Issue.6
, pp. 1637-1648
-
-
Dietrich, N.1
Bracken, A.P.2
Trinh, E.3
Schjerling, C.K.4
Koseki, H.5
Rappsilber, J.6
-
112
-
-
1342332096
-
Polycomb CBX7 has a unifying role in cellular lifespan
-
Gil J., Bernard D., Martinez D., and Beach D. Polycomb CBX7 has a unifying role in cellular lifespan. Nat Cell Biol 6 1 (2004) 67-72
-
(2004)
Nat Cell Biol
, vol.6
, Issue.1
, pp. 67-72
-
-
Gil, J.1
Bernard, D.2
Martinez, D.3
Beach, D.4
-
113
-
-
24644470607
-
CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus
-
Bernard D., Martinez-Leal J.F., Rizzo S., Martinez D., Hudson D., Visakorpi T., et al. CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus. Oncogene 24 36 (2005) 5543-5551
-
(2005)
Oncogene
, vol.24
, Issue.36
, pp. 5543-5551
-
-
Bernard, D.1
Martinez-Leal, J.F.2
Rizzo, S.3
Martinez, D.4
Hudson, D.5
Visakorpi, T.6
-
114
-
-
57649124289
-
Repression of E-cadherin by the polycomb group protein EZH2 in cancer
-
Cao Q., Yu J., Dhanasekaran S.M., Kim J.H., Mani R.S., Tomlins S.A., et al. Repression of E-cadherin by the polycomb group protein EZH2 in cancer. Oncogene 27 58 (2008) 7274-7284
-
(2008)
Oncogene
, vol.27
, Issue.58
, pp. 7274-7284
-
-
Cao, Q.1
Yu, J.2
Dhanasekaran, S.M.3
Kim, J.H.4
Mani, R.S.5
Tomlins, S.A.6
-
115
-
-
41349104897
-
Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells
-
Fujii S., and Ochiai A. Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. Cancer Sci 99 4 (2008) 738-746
-
(2008)
Cancer Sci
, vol.99
, Issue.4
, pp. 738-746
-
-
Fujii, S.1
Ochiai, A.2
-
116
-
-
47949125993
-
Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor
-
Herranz N., Pasini D., Diaz V.M., Franci C., Gutierrez A., Dave N., et al. Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol 28 15 (2008) 4772-4781
-
(2008)
Mol Cell Biol
, vol.28
, Issue.15
, pp. 4772-4781
-
-
Herranz, N.1
Pasini, D.2
Diaz, V.M.3
Franci, C.4
Gutierrez, A.5
Dave, N.6
-
117
-
-
52649125361
-
MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks
-
Morey L., Brenner C., Fazi F., Villa R., Gutierrez A., Buschbeck M., et al. MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks. Mol Cell Biol 28 19 (2008) 5912-5923
-
(2008)
Mol Cell Biol
, vol.28
, Issue.19
, pp. 5912-5923
-
-
Morey, L.1
Brenner, C.2
Fazi, F.3
Villa, R.4
Gutierrez, A.5
Buschbeck, M.6
-
118
-
-
34249869559
-
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia
-
Villa R., Pasini D., Gutierrez A., Morey L., Occhionorelli M., Vire E., et al. Role of the polycomb repressive complex 2 in acute promyelocytic leukemia. Cancer Cell 11 6 (2007) 513-525
-
(2007)
Cancer Cell
, vol.11
, Issue.6
, pp. 513-525
-
-
Villa, R.1
Pasini, D.2
Gutierrez, A.3
Morey, L.4
Occhionorelli, M.5
Vire, E.6
-
119
-
-
66149154321
-
The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation
-
Boukarabila H., Saurin A.J., Batsche E., Mossadegh N., van Lohuizen M., Otte A.P., et al. The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation. Genes Dev 23 10 (2009) 1195-1206
-
(2009)
Genes Dev
, vol.23
, Issue.10
, pp. 1195-1206
-
-
Boukarabila, H.1
Saurin, A.J.2
Batsche, E.3
Mossadegh, N.4
van Lohuizen, M.5
Otte, A.P.6
-
120
-
-
35748937338
-
Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer
-
Yu J., Cao Q., Mehra R., Laxman B., Tomlins S.A., Creighton C.J., et al. Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer. Cancer Cell 12 5 (2007) 419-431
-
(2007)
Cancer Cell
, vol.12
, Issue.5
, pp. 419-431
-
-
Yu, J.1
Cao, Q.2
Mehra, R.3
Laxman, B.4
Tomlins, S.A.5
Creighton, C.J.6
-
121
-
-
37349067098
-
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
-
Lee J., Son M.J., Woolard K., Donin N.M., Li A., Cheng C.H., et al. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell 13 1 (2008) 69-80
-
(2008)
Cancer Cell
, vol.13
, Issue.1
, pp. 69-80
-
-
Lee, J.1
Son, M.J.2
Woolard, K.3
Donin, N.M.4
Li, A.5
Cheng, C.H.6
-
122
-
-
48649091905
-
Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency
-
Chamberlain S.J., Yee D., and Magnuson T. Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency. Stem Cells 26 6 (2008) 1496-1505
-
(2008)
Stem Cells
, vol.26
, Issue.6
, pp. 1496-1505
-
-
Chamberlain, S.J.1
Yee, D.2
Magnuson, T.3
-
123
-
-
34248169728
-
The polycomb group protein Suz12 is required for embryonic stem cell differentiation
-
Pasini D., Bracken A.P., Hansen J.B., Capillo M., and Helin K. The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol Cell Biol 27 10 (2007) 3769-3779
-
(2007)
Mol Cell Biol
, vol.27
, Issue.10
, pp. 3769-3779
-
-
Pasini, D.1
Bracken, A.P.2
Hansen, J.B.3
Capillo, M.4
Helin, K.5
-
124
-
-
55949124844
-
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency
-
Shen X., Liu Y., Hsu Y.J., Fujiwara Y., Kim J., Mao X., et al. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol Cell 32 4 (2008) 491-502
-
(2008)
Mol Cell
, vol.32
, Issue.4
, pp. 491-502
-
-
Shen, X.1
Liu, Y.2
Hsu, Y.J.3
Fujiwara, Y.4
Kim, J.5
Mao, X.6
-
125
-
-
34447125133
-
The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2
-
Beke L., Nuytten M., Van Eynde A., Beullens M., and Bollen M. The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2. Oncogene 26 31 (2007) 4590-4595
-
(2007)
Oncogene
, vol.26
, Issue.31
, pp. 4590-4595
-
-
Beke, L.1
Nuytten, M.2
Van Eynde, A.3
Beullens, M.4
Bollen, M.5
-
126
-
-
64549090667
-
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells
-
Yang X., Karuturi R.K., Sun F., Aau M., Yu K., Shao R., et al. CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. PLoS ONE 4 4 (2009) e5011
-
(2009)
PLoS ONE
, vol.4
, Issue.4
-
-
Yang, X.1
Karuturi, R.K.2
Sun, F.3
Aau, M.4
Yu, K.5
Shao, R.6
-
127
-
-
0034977239
-
The polycomb-group gene Ezh2 is required for early mouse development
-
O'Carroll D., Erhardt S., Pagani M., Barton S.C., Surani M.A., and Jenuwein T. The polycomb-group gene Ezh2 is required for early mouse development. Mol Cell Biol 21 13 (2001) 4330-4336
-
(2001)
Mol Cell Biol
, vol.21
, Issue.13
, pp. 4330-4336
-
-
O'Carroll, D.1
Erhardt, S.2
Pagani, M.3
Barton, S.C.4
Surani, M.A.5
Jenuwein, T.6
-
128
-
-
67349156082
-
Bmi1 regulates mitochondrial function and the DNA damage response pathway
-
Liu J., Cao L., Chen J., Song S., Lee I.H., Quijano C., et al. Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature 459 7245 (2009) 387-392
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 387-392
-
-
Liu, J.1
Cao, L.2
Chen, J.3
Song, S.4
Lee, I.H.5
Quijano, C.6
-
129
-
-
54549127171
-
Reconstructing the disease model and epigenetic networks for MLL-AF4 leukemia
-
Zeisig B.B., Cheung N., Yeung J., and So C.W. Reconstructing the disease model and epigenetic networks for MLL-AF4 leukemia. Cancer Cell 14 5 (2008) 345-347
-
(2008)
Cancer Cell
, vol.14
, Issue.5
, pp. 345-347
-
-
Zeisig, B.B.1
Cheung, N.2
Yeung, J.3
So, C.W.4
-
130
-
-
30644474460
-
Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9
-
Greiner D., Bonaldi T., Eskeland R., Roemer E., and Imhof A. Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat Chem Biol 1 3 (2005) 143-145
-
(2005)
Nat Chem Biol
, vol.1
, Issue.3
, pp. 143-145
-
-
Greiner, D.1
Bonaldi, T.2
Eskeland, R.3
Roemer, E.4
Imhof, A.5
-
131
-
-
33846783261
-
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase
-
Kubicek S., O'Sullivan R.J., August E.M., Hickey E.R., Zhang Q., Teodoro M.L., et al. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol Cell 25 3 (2007) 473-481
-
(2007)
Mol Cell
, vol.25
, Issue.3
, pp. 473-481
-
-
Kubicek, S.1
O'Sullivan, R.J.2
August, E.M.3
Hickey, E.R.4
Zhang, Q.5
Teodoro, M.L.6
-
132
-
-
67649371461
-
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
-
Miranda T.B., Cortez C.C., Yoo C.B., Liang G., Abe M., Kelly T.K., et al. DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Mol Cancer Ther 8 6 (2009) 1579-1588
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.6
, pp. 1579-1588
-
-
Miranda, T.B.1
Cortez, C.C.2
Yoo, C.B.3
Liang, G.4
Abe, M.5
Kelly, T.K.6
-
133
-
-
34247625135
-
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
-
Tan J., Yang X., Zhuang L., Jiang X., Chen W., Lee P.L., et al. Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev 21 9 (2007) 1050-1063
-
(2007)
Genes Dev
, vol.21
, Issue.9
, pp. 1050-1063
-
-
Tan, J.1
Yang, X.2
Zhuang, L.3
Jiang, X.4
Chen, W.5
Lee, P.L.6
-
134
-
-
0032568655
-
SMART, a simple modular architecture research tool: identification of signaling domains
-
Schultz J., Milpetz F., Bork P., and Ponting C.P. SMART, a simple modular architecture research tool: identification of signaling domains. Proc Natl Acad Sci USA 95 11 (1998) 5857-5864
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.11
, pp. 5857-5864
-
-
Schultz, J.1
Milpetz, F.2
Bork, P.3
Ponting, C.P.4
-
135
-
-
52649089060
-
DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication
-
Whitman S.P., Hackanson B., Liyanarachchi S., Liu S., Rush L.J., Maharry K., et al. DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication. Blood 112 5 (2008) 2013-2016
-
(2008)
Blood
, vol.112
, Issue.5
, pp. 2013-2016
-
-
Whitman, S.P.1
Hackanson, B.2
Liyanarachchi, S.3
Liu, S.4
Rush, L.J.5
Maharry, K.6
-
136
-
-
42949100259
-
Integration of hepatitis B virus DNA into the myeloid/lymphoid or mixed-lineage leukemia (MLL4) gene and rearrangements of MLL4 in human hepatocellular carcinoma
-
Saigo K., Yoshida K., Ikeda R., Sakamoto Y., Murakami Y., Urashima T., et al. Integration of hepatitis B virus DNA into the myeloid/lymphoid or mixed-lineage leukemia (MLL4) gene and rearrangements of MLL4 in human hepatocellular carcinoma. Hum Mutat 29 5 (2008) 703-708
-
(2008)
Hum Mutat
, vol.29
, Issue.5
, pp. 703-708
-
-
Saigo, K.1
Yoshida, K.2
Ikeda, R.3
Sakamoto, Y.4
Murakami, Y.5
Urashima, T.6
-
137
-
-
47149084727
-
The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia
-
Van Vlierberghe P., van Grotel M., Tchinda J., Lee C., Beverloo H.B., van der Spek P.J., et al. The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia. Blood 111 9 (2008) 4668-4680
-
(2008)
Blood
, vol.111
, Issue.9
, pp. 4668-4680
-
-
Van Vlierberghe, P.1
van Grotel, M.2
Tchinda, J.3
Lee, C.4
Beverloo, H.B.5
van der Spek, P.J.6
-
138
-
-
26444477288
-
Increased expression of EZH2, a polycomb group protein, in bladder carcinoma
-
Arisan S., Buyuktuncer E.D., Palavan-Unsal N., Caskurlu T., Cakir O.O., and Ergenekon E. Increased expression of EZH2, a polycomb group protein, in bladder carcinoma. Urol Int 75 3 (2005) 252-257
-
(2005)
Urol Int
, vol.75
, Issue.3
, pp. 252-257
-
-
Arisan, S.1
Buyuktuncer, E.D.2
Palavan-Unsal, N.3
Caskurlu, T.4
Cakir, O.O.5
Ergenekon, E.6
-
139
-
-
29344445843
-
Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder
-
Raman J.D., Mongan N.P., Tickoo S.K., Boorjian S.A., Scherr D.S., and Gudas L.J. Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder. Clin Cancer Res 11 24 Pt 1 (2005) 8570-8576
-
(2005)
Clin Cancer Res
, vol.11
, Issue.24 PART 1
, pp. 8570-8576
-
-
Raman, J.D.1
Mongan, N.P.2
Tickoo, S.K.3
Boorjian, S.A.4
Scherr, D.S.5
Gudas, L.J.6
-
140
-
-
17144412566
-
Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases
-
Mimori K., Ogawa K., Okamoto M., Sudo T., Inoue H., and Mori M. Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases. Eur J Surg Oncol 31 4 (2005) 376-380
-
(2005)
Eur J Surg Oncol
, vol.31
, Issue.4
, pp. 376-380
-
-
Mimori, K.1
Ogawa, K.2
Okamoto, M.3
Sudo, T.4
Inoue, H.5
Mori, M.6
-
141
-
-
19944397508
-
Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma
-
Sudo T., Utsunomiya T., Mimori K., Nagahara H., Ogawa K., Inoue H., et al. Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma. Br J Cancer 92 9 (2005) 1754-1758
-
(2005)
Br J Cancer
, vol.92
, Issue.9
, pp. 1754-1758
-
-
Sudo, T.1
Utsunomiya, T.2
Mimori, K.3
Nagahara, H.4
Ogawa, K.5
Inoue, H.6
-
142
-
-
0035877978
-
Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma
-
van Kemenade F.J., Raaphorst F.M., Blokzijl T., Fieret E., Hamer K.M., Satijn D.P., et al. Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma. Blood 97 12 (2001) 3896-3901
-
(2001)
Blood
, vol.97
, Issue.12
, pp. 3896-3901
-
-
van Kemenade, F.J.1
Raaphorst, F.M.2
Blokzijl, T.3
Fieret, E.4
Hamer, K.M.5
Satijn, D.P.6
-
143
-
-
0035050744
-
The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma
-
Visser H.P., Gunster M.J., Kluin-Nelemans H.C., Menders E.M., Raaphorst F.M., Meijer C.J., et al. The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma. Br J Haematol 112 4 (2001) 950-958
-
(2001)
Br J Haematol
, vol.112
, Issue.4
, pp. 950-958
-
-
Visser, H.P.1
Gunster, M.J.2
Kluin-Nelemans, H.C.3
Menders, E.M.4
Raaphorst, F.M.5
Meijer, C.J.6
-
144
-
-
0037217478
-
NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes
-
Douglas J., Hanks S., Temple I.K., Davies S., Murray A., Upadhyaya M., et al. NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes. Am J Hum Genet 72 1 (2003) 132-143
-
(2003)
Am J Hum Genet
, vol.72
, Issue.1
, pp. 132-143
-
-
Douglas, J.1
Hanks, S.2
Temple, I.K.3
Davies, S.4
Murray, A.5
Upadhyaya, M.6
-
146
-
-
39149084348
-
Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas
-
Li J., Yin C., Okamoto H., Mushlin H., Balgley B.M., Lee C.S., et al. Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas. Neuro Oncol 10 1 (2008) 45-51
-
(2008)
Neuro Oncol
, vol.10
, Issue.1
, pp. 45-51
-
-
Li, J.1
Yin, C.2
Okamoto, H.3
Mushlin, H.4
Balgley, B.M.5
Lee, C.S.6
-
147
-
-
0035266345
-
Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression
-
Okabe H., Satoh S., Kato T., Kitahara O., Yanagawa R., Yamaoka Y., et al. Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res 61 5 (2001) 2129-2137
-
(2001)
Cancer Res
, vol.61
, Issue.5
, pp. 2129-2137
-
-
Okabe, H.1
Satoh, S.2
Kato, T.3
Kitahara, O.4
Yanagawa, R.5
Yamaoka, Y.6
-
148
-
-
33746563985
-
Loss-of-function mutations in euchromatin histone methyl transferase 1 (EHMT1) cause the 9q34 subtelomeric deletion syndrome
-
Kleefstra T., Brunner H.G., Amiel J., Oudakker A.R., Nillesen W.M., Magee A., et al. Loss-of-function mutations in euchromatin histone methyl transferase 1 (EHMT1) cause the 9q34 subtelomeric deletion syndrome. Am J Hum Genet 79 2 (2006) 370-377
-
(2006)
Am J Hum Genet
, vol.79
, Issue.2
, pp. 370-377
-
-
Kleefstra, T.1
Brunner, H.G.2
Amiel, J.3
Oudakker, A.R.4
Nillesen, W.M.5
Magee, A.6
-
149
-
-
69749123793
-
Further clinical and molecular delineation of the 9q Subtelomeric Deletion Syndrome supports a major contribution of EHMT1 haploinsufficiency to the core phenotype
-
Kleefstra T., van Zelst-Stams W.A., Nillesen W.M., Cormier-Daire V., Houge G., Foulds N., et al. Further clinical and molecular delineation of the 9q Subtelomeric Deletion Syndrome supports a major contribution of EHMT1 haploinsufficiency to the core phenotype. J Med Genet (2009)
-
(2009)
J Med Genet
-
-
Kleefstra, T.1
van Zelst-Stams, W.A.2
Nillesen, W.M.3
Cormier-Daire, V.4
Houge, G.5
Foulds, N.6
-
150
-
-
65549090043
-
Molecular mechanisms for subtelomeric rearrangements associated with the 9q34.3 microdeletion syndrome
-
Yatsenko S.A., Brundage E.K., Roney E.K., Cheung S.W., Chinault A.C., and Lupski J.R. Molecular mechanisms for subtelomeric rearrangements associated with the 9q34.3 microdeletion syndrome. Hum Mol Genet (2009)
-
(2009)
Hum Mol Genet
-
-
Yatsenko, S.A.1
Brundage, E.K.2
Roney, E.K.3
Cheung, S.W.4
Chinault, A.C.5
Lupski, J.R.6
-
151
-
-
63449115501
-
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
-
Northcott P.A., Nakahara Y., Wu X., Feuk L., Ellison D.W., Croul S., et al. Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nat Genet 41 4 (2009) 465-472
-
(2009)
Nat Genet
, vol.41
, Issue.4
, pp. 465-472
-
-
Northcott, P.A.1
Nakahara, Y.2
Wu, X.3
Feuk, L.4
Ellison, D.W.5
Croul, S.6
-
152
-
-
34447312020
-
ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease
-
Ryu H., Lee J., Hagerty S.W., Soh B.Y., McAlpin S.E., Cormier K.A., et al. ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease. Proc Natl Acad Sci USA 103 50 (2006) 19176-19181
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.50
, pp. 19176-19181
-
-
Ryu, H.1
Lee, J.2
Hagerty, S.W.3
Soh, B.Y.4
McAlpin, S.E.5
Cormier, K.A.6
-
153
-
-
33644929027
-
Enhanced SMYD3 expression is essential for the growth of breast cancer cells
-
Hamamoto R., Silva F.P., Tsuge M., Nishidate T., Katagiri T., Nakamura Y., et al. Enhanced SMYD3 expression is essential for the growth of breast cancer cells. Cancer Sci 97 2 (2006) 113-118
-
(2006)
Cancer Sci
, vol.97
, Issue.2
, pp. 113-118
-
-
Hamamoto, R.1
Silva, F.P.2
Tsuge, M.3
Nishidate, T.4
Katagiri, T.5
Nakamura, Y.6
-
154
-
-
27144496194
-
A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers
-
Tsuge M., Hamamoto R., Silva F.P., Ohnishi Y., Chayama K., Kamatani N., et al. A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers. Nat Genet 37 10 (2005) 1104-1107
-
(2005)
Nat Genet
, vol.37
, Issue.10
, pp. 1104-1107
-
-
Tsuge, M.1
Hamamoto, R.2
Silva, F.P.3
Ohnishi, Y.4
Chayama, K.5
Kamatani, N.6
-
155
-
-
4143074854
-
SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells
-
Hamamoto R., Furukawa Y., Morita M., Iimura Y., Silva F.P., Li M., et al. SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nat Cell Biol 6 8 (2004) 731-740
-
(2004)
Nat Cell Biol
, vol.6
, Issue.8
, pp. 731-740
-
-
Hamamoto, R.1
Furukawa, Y.2
Morita, M.3
Iimura, Y.4
Silva, F.P.5
Li, M.6
-
156
-
-
65949117245
-
Identification of Smyd4 as a potential tumor suppressor gene involved in breast cancer development
-
Hu L., Zhu Y.T., Qi C., and Zhu Y.J. Identification of Smyd4 as a potential tumor suppressor gene involved in breast cancer development. Cancer Res (2009)
-
(2009)
Cancer Res
-
-
Hu, L.1
Zhu, Y.T.2
Qi, C.3
Zhu, Y.J.4
-
157
-
-
0032188763
-
RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis
-
He L., Yu J.X., Liu L., Buyse I.M., Wang M.S., Yang Q.C., et al. RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis. Cancer Res 58 19 (1998) 4238-4244
-
(1998)
Cancer Res
, vol.58
, Issue.19
, pp. 4238-4244
-
-
He, L.1
Yu, J.X.2
Liu, L.3
Buyse, I.M.4
Wang, M.S.5
Yang, Q.C.6
-
158
-
-
0035449997
-
Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily
-
Steele-Perkins G., Fang W., Yang X.H., Van Gele M., Carling T., Gu J., et al. Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily. Genes Dev 15 17 (2001) 2250-2262
-
(2001)
Genes Dev
, vol.15
, Issue.17
, pp. 2250-2262
-
-
Steele-Perkins, G.1
Fang, W.2
Yang, X.H.3
Van Gele, M.4
Carling, T.5
Gu, J.6
-
159
-
-
2342564968
-
Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma
-
Oshimo Y., Oue N., Mitani Y., Nakayama H., Kitadai Y., Yoshida K., et al. Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma. Int J Cancer 110 2 (2004) 212-218
-
(2004)
Int J Cancer
, vol.110
, Issue.2
, pp. 212-218
-
-
Oshimo, Y.1
Oue, N.2
Mitani, Y.3
Nakayama, H.4
Kitadai, Y.5
Yoshida, K.6
-
160
-
-
0032880408
-
Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1
-
Jiang G., Liu L., Buyse I.M., Simon D., and Huang S. Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1. Int J Cancer 83 4 (1999) 541-546
-
(1999)
Int J Cancer
, vol.83
, Issue.4
, pp. 541-546
-
-
Jiang, G.1
Liu, L.2
Buyse, I.M.3
Simon, D.4
Huang, S.5
-
161
-
-
0742272092
-
A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion
-
Reid A.G., and Nacheva E.P. A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion. Leukemia 18 1 (2004) 178-180
-
(2004)
Leukemia
, vol.18
, Issue.1
, pp. 178-180
-
-
Reid, A.G.1
Nacheva, E.P.2
-
162
-
-
35448972855
-
Gene amplification and overexpression of PRDM14 in breast cancers
-
Nishikawa N., Toyota M., Suzuki H., Honma T., Fujikane T., Ohmura T., et al. Gene amplification and overexpression of PRDM14 in breast cancers. Cancer Res 67 20 (2007) 9649-9657
-
(2007)
Cancer Res
, vol.67
, Issue.20
, pp. 9649-9657
-
-
Nishikawa, N.1
Toyota, M.2
Suzuki, H.3
Honma, T.4
Fujikane, T.5
Ohmura, T.6
-
163
-
-
36348969300
-
Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization
-
Goulet I., Gauvin G., Boisvenue S., and Cote J. Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization. J Biol Chem 282 45 (2007) 33009-33021
-
(2007)
J Biol Chem
, vol.282
, Issue.45
, pp. 33009-33021
-
-
Goulet, I.1
Gauvin, G.2
Boisvenue, S.3
Cote, J.4
-
164
-
-
33748624090
-
Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene
-
El Messaoudi S., Fabbrizio E., Rodriguez C., Chuchana P., Fauquier L., Cheng D., et al. Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene. Proc Natl Acad Sci USA 103 36 (2006) 13351-13356
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.36
, pp. 13351-13356
-
-
El Messaoudi, S.1
Fabbrizio, E.2
Rodriguez, C.3
Chuchana, P.4
Fauquier, L.5
Cheng, D.6
-
165
-
-
3042536209
-
Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status
-
Hong H., Kao C., Jeng M.H., Eble J.N., Koch M.O., Gardner T.A., et al. Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status. Cancer 101 1 (2004) 83-89
-
(2004)
Cancer
, vol.101
, Issue.1
, pp. 83-89
-
-
Hong, H.1
Kao, C.2
Jeng, M.H.3
Eble, J.N.4
Koch, M.O.5
Gardner, T.A.6
-
166
-
-
33748359520
-
Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability
-
Majumder S., Liu Y., Ford III O.H., Mohler J.L., and Whang Y.E. Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability. Prostate 66 12 (2006) 1292-1301
-
(2006)
Prostate
, vol.66
, Issue.12
, pp. 1292-1301
-
-
Majumder, S.1
Liu, Y.2
Ford III, O.H.3
Mohler, J.L.4
Whang, Y.E.5
-
167
-
-
34547741040
-
Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma
-
Pal S., Baiocchi R.A., Byrd J.C., Grever M.R., Jacob S.T., and Sif S. Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma. EMBO J 26 15 (2007) 3558-3569
-
(2007)
EMBO J
, vol.26
, Issue.15
, pp. 3558-3569
-
-
Pal, S.1
Baiocchi, R.A.2
Byrd, J.C.3
Grever, M.R.4
Jacob, S.T.5
Sif, S.6
-
168
-
-
53549103598
-
Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells
-
Wang L., Pal S., and Sif S. Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells. Mol Cell Biol 28 20 (2008) 6262-6277
-
(2008)
Mol Cell Biol
, vol.28
, Issue.20
, pp. 6262-6277
-
-
Wang, L.1
Pal, S.2
Sif, S.3
-
169
-
-
70350500219
-
Polycomb group proteins: navigators of lineage pathways led astray in cancer
-
Bracken A.P., and Helin K. Polycomb group proteins: navigators of lineage pathways led astray in cancer. Nat Rev Cancer 9 11 (2009) 773-784
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.11
, pp. 773-784
-
-
Bracken, A.P.1
Helin, K.2
|