-
1
-
-
11844301282
-
Medulloblastoma: Developmental mechanisms out of control
-
Marino, S. Medulloblastoma: developmental mechanisms out of control. Trends Mol. Med. 11, 17-22 (2005).
-
(2005)
Trends Mol. Med
, vol.11
, pp. 17-22
-
-
Marino, S.1
-
2
-
-
0030776230
-
Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization
-
Reardon, D.A. et al. Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization. Cancer Res. 57, 4042-4047 (1997).
-
(1997)
Cancer Res
, vol.57
, pp. 4042-4047
-
-
Reardon, D.A.1
-
3
-
-
0033860991
-
Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping
-
Bayani, J. et al. Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping. J. Neurosurg. 93, 437-448 (2000).
-
(2000)
J. Neurosurg
, vol.93
, pp. 437-448
-
-
Bayani, J.1
-
4
-
-
38049100456
-
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
-
Beroukhim, R. et al. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc. Natl. Acad. Sci. USA 104, 20007-20012 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20007-20012
-
-
Beroukhim, R.1
-
5
-
-
0037052539
-
A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells
-
Ogawa, H., Ishiguro, K., Gaubatz, S., Livingston, D.M. & Nakatani, Y. A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. Science 296, 1132-1136 (2002).
-
(2002)
Science
, vol.296
, pp. 1132-1136
-
-
Ogawa, H.1
Ishiguro, K.2
Gaubatz, S.3
Livingston, D.M.4
Nakatani, Y.5
-
6
-
-
33745151459
-
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities
-
Klymenko, T. et al. A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Genes Dev. 20, 1110-1122 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 1110-1122
-
-
Klymenko, T.1
-
7
-
-
34147224008
-
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
-
Mullighan, C.G. et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446, 758-764 (2007).
-
(2007)
Nature
, vol.446
, pp. 758-764
-
-
Mullighan, C.G.1
-
8
-
-
36248980204
-
Characterizing the cancer genome in lung adenocarcinoma
-
Weir, B.A. et al. Characterizing the cancer genome in lung adenocarcinoma. Nature 450, 893-898 (2007).
-
(2007)
Nature
, vol.450
, pp. 893-898
-
-
Weir, B.A.1
-
9
-
-
33746332412
-
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
-
Cloos, P.A. et al. The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature 442, 307-311 (2006).
-
(2006)
Nature
, vol.442
, pp. 307-311
-
-
Cloos, P.A.1
-
10
-
-
33846132573
-
Diversity within the JMJD2 histone demethylase family
-
Shin, S. & Janknecht, R. Diversity within the JMJD2 histone demethylase family. Biochem. Biophys. Res. Commun. 353, 973-977 (2007).
-
(2007)
Biochem. Biophys. Res. Commun
, vol.353
, pp. 973-977
-
-
Shin, S.1
Janknecht, R.2
-
11
-
-
0242669199
-
Coordinated histone modifications mediated by a CtBP co-repressor complex
-
Shi, Y. et al. Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature 422, 735-738 (2003).
-
(2003)
Nature
, vol.422
, pp. 735-738
-
-
Shi, Y.1
-
12
-
-
33745146571
-
Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells
-
Fodor, B.D. et al. Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells. Genes Dev. 20, 1557-1562 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 1557-1562
-
-
Fodor, B.D.1
-
13
-
-
0035577668
-
Histone H3 specific acetyltransferases are essential for cell cycle progression
-
Howe, L. et al. Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev. 15, 3144-3154 (2001).
-
(2001)
Genes Dev
, vol.15
, pp. 3144-3154
-
-
Howe, L.1
-
14
-
-
34547201576
-
A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression
-
Lu, J., Ruhf, M.L., Perrimon, N. & Leder, P. A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proc. Natl. Acad. Sci. USA 104, 9381-9386 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 9381-9386
-
-
Lu, J.1
Ruhf, M.L.2
Perrimon, N.3
Leder, P.4
-
15
-
-
0034656212
-
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
-
Marino, S., Vooijs, M., van Der Gulden, H., Jonkers, J. & Berns, A. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev. 14, 994-1004 (2000).
-
(2000)
Genes Dev
, vol.14
, pp. 994-1004
-
-
Marino, S.1
Vooijs, M.2
van Der Gulden, H.3
Jonkers, J.4
Berns, A.5
-
16
-
-
34249337114
-
Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors
-
Olson, M.V. et al. Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors. Cancer Res. 67, 4005-4009 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 4005-4009
-
-
Olson, M.V.1
-
17
-
-
0037232580
-
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
-
Kenney, A.M., Cole, M.D. & Rowitch, D.H. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development 130, 15-28 (2003).
-
(2003)
Development
, vol.130
, pp. 15-28
-
-
Kenney, A.M.1
Cole, M.D.2
Rowitch, D.H.3
-
18
-
-
0037108268
-
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
-
Knoepfler, P.S., Cheng, P.F. & Eisenman, R.N. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 16, 2699-2712 (2002).
-
(2002)
Genes Dev
, vol.16
, pp. 2699-2712
-
-
Knoepfler, P.S.1
Cheng, P.F.2
Eisenman, R.N.3
-
19
-
-
0042977676
-
Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence
-
Marino, S., Hoogervoorst, D., Brandner, S. & Berns, A. Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence. Development 130, 3359-3368 (2003).
-
(2003)
Development
, vol.130
, pp. 3359-3368
-
-
Marino, S.1
Hoogervoorst, D.2
Brandner, S.3
Berns, A.4
-
20
-
-
0027253756
-
A temperature-sensitive brain tumor suppressor mutation of Drosophila melanogaster: Developmental studies and molecular localization of the gene
-
Gateff, E., Loffler, T. & Wismar, J. A temperature-sensitive brain tumor suppressor mutation of Drosophila melanogaster: developmental studies and molecular localization of the gene. Mech. Dev. 41, 15-31 (1993).
-
(1993)
Mech. Dev
, vol.41
, pp. 15-31
-
-
Gateff, E.1
Loffler, T.2
Wismar, J.3
-
21
-
-
0035852632
-
The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
-
Trimarchi, J.M., Fairchild, B., Wen, J. & Lees, J.A. The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc. Natl. Acad. Sci. USA 98, 1519-1524 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1519-1524
-
-
Trimarchi, J.M.1
Fairchild, B.2
Wen, J.3
Lees, J.A.4
-
22
-
-
1642633053
-
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
-
Leung, C. et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 428, 337-341 (2004).
-
(2004)
Nature
, vol.428
, pp. 337-341
-
-
Leung, C.1
-
23
-
-
34347354307
-
Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis
-
Wiederschain, D. et al. Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis. Mol. Cell. Biol. 27, 4968-4979 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 4968-4979
-
-
Wiederschain, D.1
-
24
-
-
0032490832
-
-
Cartwright, P., Muller, H., Wagener, C., Holm, K. & Helin, K. E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene 17, 611-623 (1998).
-
Cartwright, P., Muller, H., Wagener, C., Holm, K. & Helin, K. E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene 17, 611-623 (1998).
-
-
-
-
25
-
-
34547751335
-
HP1alpha guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation
-
Panteleeva, I. et al. HP1alpha guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation. EMBO J. 26, 3616-3628 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 3616-3628
-
-
Panteleeva, I.1
-
26
-
-
33745141913
-
Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells
-
Thomas, T. et al. Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells. Genes Dev. 20, 1175-1186 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 1175-1186
-
-
Thomas, T.1
-
27
-
-
34547562418
-
Frequent engagement of the classical and alternative NFkappaB pathways by diverse genetic abnormalities in multiple myeloma
-
Annunziata, C.M. et al. Frequent engagement of the classical and alternative NFkappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 12, 115-130 (2007).
-
(2007)
Cancer Cell
, vol.12
, pp. 115-130
-
-
Annunziata, C.M.1
-
28
-
-
4544285754
-
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice
-
Romer, J.T. et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell 6, 229-240 (2004).
-
(2004)
Cancer Cell
, vol.6
, pp. 229-240
-
-
Romer, J.T.1
-
29
-
-
33846783261
-
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase
-
Kubicek, S. et al. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol. Cell 25, 473-481 (2007).
-
(2007)
Mol. Cell
, vol.25
, pp. 473-481
-
-
Kubicek, S.1
-
30
-
-
33646362581
-
Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations
-
Thompson, M.C. et al. Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J. Clin. Oncol. 24, 1924-1931 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 1924-1931
-
-
Thompson, M.C.1
|