-
1
-
-
0038675193
-
Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma
-
Bergsagel PL, Kuehl WM. Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma. Immunol Rev. 2003;194:96-104.
-
(2003)
Immunol Rev
, vol.194
, pp. 96-104
-
-
Bergsagel, P.L.1
Kuehl, W.M.2
-
2
-
-
27244445489
-
Molecular pathogenesis and a consequent classification of multiple myeloma
-
Bergsagel PL, Kuehl WM. Molecular pathogenesis and a consequent classification of multiple myeloma. J Clin Oncol. 2005;23:6333-6338.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6333-6338
-
-
Bergsagel, P.L.1
Kuehl, W.M.2
-
3
-
-
33751075190
-
Ten years and counting: So what do we know about t(4;14)(p16;q32) multiple myeloma
-
Keats JJ, Reiman T, Belch AR, Pilarski LM. Ten years and counting: so what do we know about t(4;14)(p16;q32) multiple myeloma. Leuk Lymphoma. 2006;47:2289-2300.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 2289-2300
-
-
Keats, J.J.1
Reiman, T.2
Belch, A.R.3
Pilarski, L.M.4
-
4
-
-
0037441747
-
In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression
-
Keats JJ, Reiman T, Maxwell CA, et al. In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression. Blood. 2003;101:1520-1529.
-
(2003)
Blood
, vol.101
, pp. 1520-1529
-
-
Keats, J.J.1
Reiman, T.2
Maxwell, C.A.3
-
5
-
-
20844463416
-
Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients
-
Keats JJ, Maxwell CA, Taylor BJ, et al. Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients. Blood. 2005;105:4060-4069.
-
(2005)
Blood
, vol.105
, pp. 4060-4069
-
-
Keats, J.J.1
Maxwell, C.A.2
Taylor, B.J.3
-
6
-
-
0037443417
-
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript
-
Santra M, Zhan F, Tian E, Barlogie B, Shaughnessy J Jr. A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript. Blood. 2003;101:2374-2376.
-
(2003)
Blood
, vol.101
, pp. 2374-2376
-
-
Santra, M.1
Zhan, F.2
Tian, E.3
Barlogie, B.4
Shaughnessy Jr, J.5
-
7
-
-
0032212243
-
The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts
-
Chesi M, Nardini E, Lim RS, Smith KD, Kuehl WM, Bergsagel PL. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts. Blood. 1998;92:3025-3034.
-
(1998)
Blood
, vol.92
, pp. 3025-3034
-
-
Chesi, M.1
Nardini, E.2
Lim, R.S.3
Smith, K.D.4
Kuehl, W.M.5
Bergsagel, P.L.6
-
8
-
-
0031779421
-
WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma
-
Stec I, Wright TJ, van Ommen GJ, et al. WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma. Hum Mol Genet. 1998;7:1071-1082.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1071-1082
-
-
Stec, I.1
Wright, T.J.2
van Ommen, G.J.3
-
9
-
-
0035146045
-
A unique mRNA initiated within a middle intron of WHSC1/MMSET encodes a DNA binding protein that suppresses human IL-5 transcription
-
Garlisi CG, Uss AS, Xiao H, et al. A unique mRNA initiated within a middle intron of WHSC1/MMSET encodes a DNA binding protein that suppresses human IL-5 transcription. Am J Respir Cell Mol Biol. 2001;24:90-98.
-
(2001)
Am J Respir Cell Mol Biol
, vol.24
, pp. 90-98
-
-
Garlisi, C.G.1
Uss, A.S.2
Xiao, H.3
-
10
-
-
32944460060
-
Transcription repression activity is associated with the type I isoform of the MMSET gene involved in t(4;14) in multiple myeloma
-
Todoerti K, Ronchetti D, Agnelli L, et al. Transcription repression activity is associated with the type I isoform of the MMSET gene involved in t(4;14) in multiple myeloma. Br J Haematol. 2005;131:214-218.
-
(2005)
Br J Haematol
, vol.131
, pp. 214-218
-
-
Todoerti, K.1
Ronchetti, D.2
Agnelli, L.3
-
11
-
-
17444434208
-
Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses
-
Kohli M, Rago C, Lengauer C, Kinzler KW, Vogelstein B. Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses. Nucleic Acids Res. 2004;32:e3.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Kohli, M.1
Rago, C.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
-
12
-
-
0035989649
-
Targeted transgene insertion into human chromosomes by adeno-associated virus vectors
-
Hirata R, Chamberlain J, Dong R, Russell DW. Targeted transgene insertion into human chromosomes by adeno-associated virus vectors. Nat Biotechnol. 2002;20:735-738.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 735-738
-
-
Hirata, R.1
Chamberlain, J.2
Dong, R.3
Russell, D.W.4
-
13
-
-
28544435657
-
Improved methods for the generation of human gene knockout and knockin cell lines
-
Topaloglu O, Hurley PJ, Yildirim O, Civin CI, Bunz F. Improved methods for the generation of human gene knockout and knockin cell lines. Nucleic Acids Res. 2005;33:e158.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Topaloglu, O.1
Hurley, P.J.2
Yildirim, O.3
Civin, C.I.4
Bunz, F.5
-
14
-
-
38349184853
-
High-throughput screening of somatic cell gene targeting events using a multi-dimensional sample pooling approach
-
Konishi H, Lauring J, Garay J, et al. High-throughput screening of somatic cell gene targeting events using a multi-dimensional sample pooling approach. Nat Protocols. 2007;2:2865-2874.
-
(2007)
Nat Protocols
, vol.2
, pp. 2865-2874
-
-
Konishi, H.1
Lauring, J.2
Garay, J.3
-
15
-
-
34548710863
-
Knockin of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras-mediated transformation
-
Konishi H, Karakas B, Abukhdeir AM, et al. Knockin of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras-mediated transformation. Cancer Res. 2007;67:8460-8467.
-
(2007)
Cancer Res
, vol.67
, pp. 8460-8467
-
-
Konishi, H.1
Karakas, B.2
Abukhdeir, A.M.3
-
16
-
-
0003633755
-
-
Institute of Laboratory Animals Resources, Commission on Life Sciences, National Research Council, 7th ed. Washington, DC: National Academy Press;
-
Institute of Laboratory Animals Resources, Commission on Life Sciences, National Research Council. Guide for the Care and Use of Laboratory Animals. 7th ed. Washington, DC: National Academy Press; 1996.
-
(1996)
Guide for the Care and Use of Laboratory Animals
-
-
-
17
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
Sledz CA, Holko M, de Veer MJ, Silverman RH, Williams BR. Activation of the interferon system by short-interfering RNAs. Nat Cell Biol. 2003;5:834-839.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 834-839
-
-
Sledz, C.A.1
Holko, M.2
de Veer, M.J.3
Silverman, R.H.4
Williams, B.R.5
-
18
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge AJ, Pebernard S, Ducraux A, Nicoulaz AL, Iggo R. Induction of an interferon response by RNAi vectors in mammalian cells. Nat Genet. 2003;34:263-264.
-
(2003)
Nat Genet
, vol.34
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
Nicoulaz, A.L.4
Iggo, R.5
-
19
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm D, Streetz KL, Jopling CL, et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature. 2006;441:537-541.
-
(2006)
Nature
, vol.441
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
-
20
-
-
22344454846
-
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
-
Judge AD, Sood V, Shaw JR, Fang D, McClintock K, MacLachlan I. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005;23:457-462.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 457-462
-
-
Judge, A.D.1
Sood, V.2
Shaw, J.R.3
Fang, D.4
McClintock, K.5
MacLachlan, I.6
-
21
-
-
10744219688
-
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
-
Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, et al. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A. 2004;101:1892-1897.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1892-1897
-
-
Scacheri, P.C.1
Rozenblatt-Rosen, O.2
Caplen, N.J.3
-
22
-
-
38349113261
-
p21 gene knock down does not identify genetic effectors seen with gene knock out
-
Karakas B, Weeraratna AT, Abukhdeir AM, et al. p21 gene knock down does not identify genetic effectors seen with gene knock out. Cancer Biol Ther. 2007;6:7.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 7
-
-
Karakas, B.1
Weeraratna, A.T.2
Abukhdeir, A.M.3
-
23
-
-
0033887241
-
Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription- polymerase chain reaction analysis of IGH-MMSET fusion transcripts
-
Malgeri U, Baldini L, Perfetti V, et al. Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription- polymerase chain reaction analysis of IGH-MMSET fusion transcripts. Cancer Res. 2000;60:4058-4061.
-
(2000)
Cancer Res
, vol.60
, pp. 4058-4061
-
-
Malgeri, U.1
Baldini, L.2
Perfetti, V.3
-
24
-
-
27244449162
-
Identification of ID-1 as a potential target gene of MMSET in multiple myeloma
-
Hudlebusch HR, Theilgaard-Monch K, Lodahl M, Johnsen HE, Rasmussen T. Identification of ID-1 as a potential target gene of MMSET in multiple myeloma. Br J Haematol. 2005;130:700-708.
-
(2005)
Br J Haematol
, vol.130
, pp. 700-708
-
-
Hudlebusch, H.R.1
Theilgaard-Monch, K.2
Lodahl, M.3
Johnsen, H.E.4
Rasmussen, T.5
-
25
-
-
4444225963
-
A global expression-based analysis of the consequences of the t(4;14) translocation in myeloma
-
Dring AM, Davies FE, Fenton JA, et al. A global expression-based analysis of the consequences of the t(4;14) translocation in myeloma. Clin Cancer Res. 2004;10:5692-5701.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5692-5701
-
-
Dring, A.M.1
Davies, F.E.2
Fenton, J.A.3
-
26
-
-
33644680752
-
Molecular classification of multiple myeloma: A distinct transcriptional profile characterizes patients expressing CCND1 and negative for 14q32 translocations
-
Agnelli L, Bicciato S, Mattioli M, et al. Molecular classification of multiple myeloma: a distinct transcriptional profile characterizes patients expressing CCND1 and negative for 14q32 translocations. J Clin Oncol. 2005;23:7296-7306.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7296-7306
-
-
Agnelli, L.1
Bicciato, S.2
Mattioli, M.3
-
27
-
-
20944437020
-
Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma
-
Mattioli M, Agnelli L, Fabris S, et al. Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma. Oncogene. 2005;24:2461-2473.
-
(2005)
Oncogene
, vol.24
, pp. 2461-2473
-
-
Mattioli, M.1
Agnelli, L.2
Fabris, S.3
-
28
-
-
3242777803
-
Advances in biology of multiple myeloma: Clinical applications
-
Hideshima T, Bergsagel PL, Kuehl WM, Anderson KC. Advances in biology of multiple myeloma: clinical applications. Blood. 2004;104:607-618.
-
(2004)
Blood
, vol.104
, pp. 607-618
-
-
Hideshima, T.1
Bergsagel, P.L.2
Kuehl, W.M.3
Anderson, K.C.4
-
29
-
-
0031839633
-
Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma
-
Chesi M, Bergsagel PL, Shonukan OO, et al. Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood. 1998;91:4457-4463.
-
(1998)
Blood
, vol.91
, pp. 4457-4463
-
-
Chesi, M.1
Bergsagel, P.L.2
Shonukan, O.O.3
-
30
-
-
1442285889
-
Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma
-
Hurt EM, Wiestner A, Rosenwald A, et al. Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma. Cancer Cell. 2004;5:191-199.
-
(2004)
Cancer Cell
, vol.5
, pp. 191-199
-
-
Hurt, E.M.1
Wiestner, A.2
Rosenwald, A.3
-
31
-
-
15744392410
-
Fibroblast growth factor receptor 3 inhibition by short hairpin RNAs leads to apoptosis in multiple myeloma
-
Zhu L, Somlo G, Zhou B, et al. Fibroblast growth factor receptor 3 inhibition by short hairpin RNAs leads to apoptosis in multiple myeloma. Mol Cancer Ther. 2005;4:787-798.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 787-798
-
-
Zhu, L.1
Somlo, G.2
Zhou, B.3
|