-
1
-
-
0036512435
-
Multiple myeloma: Evolving genetic events and host interactions
-
Kuehl WM, Bergsagel PL. Multiple myeloma: evolving genetic events and host interactions. Nat Rev Cancer 2002;2:175-87.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 175-187
-
-
Kuehl, W.M.1
Bergsagel, P.L.2
-
2
-
-
0030827222
-
IgH translocations in multiple myeloma: A nearly universal event that rarely involves cmyc
-
Bergsagel PL, Nardini E, Brents L, Chesi M, Kuehl WM. IgH translocations in multiple myeloma: a nearly universal event that rarely involves cmyc. Curr Top Microbiol Immunol 1997;224:283-7.
-
(1997)
Curr Top Microbiol Immunol
, vol.224
, pp. 283-287
-
-
Bergsagel, P.L.1
Nardini, E.2
Brents, L.3
Chesi, M.4
Kuehl, W.M.5
-
3
-
-
0030842266
-
A novel chromosomal translocation t(4; 14)(p16.3; q32) in multiple myeloma involves the fibroblast growth-factor receptor 3 gene
-
Richelda R, Ronchetti D, Baldini L, Cro L, Viggiano L, Marzella R, et al. A novel chromosomal translocation t(4; 14)(p16.3; q32) in multiple myeloma involves the fibroblast growth-factor receptor 3 gene. Blood 1997;90:4062-70.
-
(1997)
Blood
, vol.90
, pp. 4062-4070
-
-
Richelda, R.1
Ronchetti, D.2
Baldini, L.3
Cro, L.4
Viggiano, L.5
Marzella, R.6
-
4
-
-
0035254612
-
Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma
-
Chesi M, Brents LA, Ely SA, Bais C, Robbiani DF, Mesri EA, et al. Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma. Blood 2001;97:729-36.
-
(2001)
Blood
, vol.97
, pp. 729-736
-
-
Chesi, M.1
Brents, L.A.2
Ely, S.A.3
Bais, C.4
Robbiani, D.F.5
Mesri, E.A.6
-
5
-
-
20844463416
-
Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients
-
Keats JJ, Maxwell CA, Taylor BJ, Hendzel MJ, Chesi M, Bergsagel PL, et al. Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients. Blood 2005;105:4060-9.
-
(2005)
Blood
, vol.105
, pp. 4060-4069
-
-
Keats, J.J.1
Maxwell, C.A.2
Taylor, B.J.3
Hendzel, M.J.4
Chesi, M.5
Bergsagel, P.L.6
-
6
-
-
0034142212
-
Ectopic expression of fibroblast growth factor receptor 3 promotes myeloma cell proliferation and prevents apoptosis
-
Plowright EE, Li Z, Bergsagel PL, Chesi M, Barber DL, Branch DR, et al. Ectopic expression of fibroblast growth factor receptor 3 promotes myeloma cell proliferation and prevents apoptosis. Blood 2000;95:992-8.
-
(2000)
Blood
, vol.95
, pp. 992-998
-
-
Plowright, E.E.1
Li, Z.2
Bergsagel, P.L.3
Chesi, M.4
Barber, D.L.5
Branch, D.R.6
-
7
-
-
0035858985
-
Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): Comparative analysis of Y373C, K650E and the novel G384D mutations
-
Ronchetti D, Greco A, Compasso S, Colombo G, Dell'Era P, Otsuki T, et al. Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations. Oncogene 2001;20:3553-62.
-
(2001)
Oncogene
, vol.20
, pp. 3553-3562
-
-
Ronchetti, D.1
Greco, A.2
Compasso, S.3
Colombo, G.4
Dell'Era, P.5
Otsuki, T.6
-
8
-
-
0037443417
-
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript
-
Santra M, Zhan F, Tian E, Barlogie B, Shaughnessy J Jr. A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript. Blood 2003;101:2374-6.
-
(2003)
Blood
, vol.101
, pp. 2374-2376
-
-
Santra, M.1
Zhan, F.2
Tian, E.3
Barlogie, B.4
Shaughnessy Jr, J.5
-
9
-
-
0036036768
-
A molecular study of the t(4;14) in multiple myeloma
-
Sibley K, Fenton JA, Dring AM, Ashcroft AJ, Rawstron AC, Morgan GJ. A molecular study of the t(4;14) in multiple myeloma. Br J Haematol 2002;118:514-20.
-
(2002)
Br J Haematol
, vol.118
, pp. 514-520
-
-
Sibley, K.1
Fenton, J.A.2
Dring, A.M.3
Ashcroft, A.J.4
Rawstron, A.C.5
Morgan, G.J.6
-
10
-
-
1942456800
-
Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma
-
Trudel S, Ely S, Farooqi Y, Affer M, Robbiani DF, Chesi M, et al. Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma. Blood 2004;103:3521-8.
-
(2004)
Blood
, vol.103
, pp. 3521-3528
-
-
Trudel, S.1
Ely, S.2
Farooqi, Y.3
Affer, M.4
Robbiani, D.F.5
Chesi, M.6
-
11
-
-
0037441747
-
In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression
-
Keats JJ, Reiman T, Maxwell CA, Taylor BJ, Larratt LM, Mant MJ, et al. In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression. Blood 2003;101:1520-9.
-
(2003)
Blood
, vol.101
, pp. 1520-1529
-
-
Keats, J.J.1
Reiman, T.2
Maxwell, C.A.3
Taylor, B.J.4
Larratt, L.M.5
Mant, M.J.6
-
12
-
-
38349087546
-
The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity
-
Lauring J, Abukhdeir AM, Konishi H, Garay JP, Gustin JP, Wang Q, et al. The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity. Blood 2008;111:856-64.
-
(2008)
Blood
, vol.111
, pp. 856-864
-
-
Lauring, J.1
Abukhdeir, A.M.2
Konishi, H.3
Garay, J.P.4
Gustin, J.P.5
Wang, Q.6
-
13
-
-
36148955443
-
Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma
-
Jenner MW, Leone PE, Walker BA, Ross FM, Johnson DC, Gonzalez D, et al. Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma. Blood 2007;110:3291-300.
-
(2007)
Blood
, vol.110
, pp. 3291-3300
-
-
Jenner, M.W.1
Leone, P.E.2
Walker, B.A.3
Ross, F.M.4
Johnson, D.C.5
Gonzalez, D.6
-
14
-
-
33748190743
-
Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma
-
Walker BA, Leone PE, Jenner MW, Li C, Gonzalez D, Johnson DC, et al. Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma. Blood 2006;108:1733-43.
-
(2006)
Blood
, vol.108
, pp. 1733-1743
-
-
Walker, B.A.1
Leone, P.E.2
Jenner, M.W.3
Li, C.4
Gonzalez, D.5
Johnson, D.C.6
-
15
-
-
0042121250
-
ChipInfo: Software for extracting gene annotation and gene ontology information for microarray analysis
-
Zhong S, Li C, Wong WH. ChipInfo: Software for extracting gene annotation and gene ontology information for microarray analysis. Nucleic Acids Res 2003;31:3483-6.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3483-3486
-
-
Zhong, S.1
Li, C.2
Wong, W.H.3
-
16
-
-
34547589578
-
-
Huang da W, Sherman BT, Tan Q, Kir J, Liu D, Bryant D, et al. DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res 2007;35(Web Server issue):W169-75.
-
Huang da W, Sherman BT, Tan Q, Kir J, Liu D, Bryant D, et al. DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res 2007;35(Web Server issue):W169-75.
-
-
-
-
18
-
-
0029087973
-
Nuclear delivery of antisense oligodeoxynucleotides through reversible permeabilization of human leukemia cells with streptolysin O
-
Spring;
-
Spiller DG, Tidd DM. Nuclear delivery of antisense oligodeoxynucleotides through reversible permeabilization of human leukemia cells with streptolysin O. Antisense Res Dev 1995 Spring;5:13-21.
-
(1995)
Antisense Res Dev
, Issue.5
, pp. 13-21
-
-
Spiller, D.G.1
Tidd, D.M.2
-
19
-
-
41149088657
-
Streptolysin-O reversible permeabilisation is an effective method to transfect siRNAs into myeloma cells
-
Brito JL, Davies FE, Gonzalez D, Morgan GJ. Streptolysin-O reversible permeabilisation is an effective method to transfect siRNAs into myeloma cells. J Immunol Methods 2008;333:147-55.
-
(2008)
J Immunol Methods
, vol.333
, pp. 147-155
-
-
Brito, J.L.1
Davies, F.E.2
Gonzalez, D.3
Morgan, G.J.4
-
20
-
-
3042834284
-
Correlation of TACC3, FGFR3, MMSET and p21 expression with the t(4;14)(p16.3;q32) in multiple myeloma
-
Stewart JP, Thompson A, Santra M, Barlogie B, Lappin TR, Shaughnessy J Jr. Correlation of TACC3, FGFR3, MMSET and p21 expression with the t(4;14)(p16.3;q32) in multiple myeloma. Br J Haematol 2004;126:72-6.
-
(2004)
Br J Haematol
, vol.126
, pp. 72-76
-
-
Stewart, J.P.1
Thompson, A.2
Santra, M.3
Barlogie, B.4
Lappin, T.R.5
Shaughnessy Jr., J.6
-
21
-
-
42449161943
-
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor
-
Marango J, Shimoyama M, Nishio H, Meyer JA, Min DJ, Sirulnik A, et al. The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood 2008;111:3145-54.
-
(2008)
Blood
, vol.111
, pp. 3145-3154
-
-
Marango, J.1
Shimoyama, M.2
Nishio, H.3
Meyer, J.A.4
Min, D.J.5
Sirulnik, A.6
-
22
-
-
33745779502
-
The molecular classification of multiple myeloma
-
Zhan F, Huang Y, Colla S, Stewart JP, Hanamura I, Gupta S, et al. The molecular classification of multiple myeloma. Blood 2006;108:2020-8.
-
(2006)
Blood
, vol.108
, pp. 2020-2028
-
-
Zhan, F.1
Huang, Y.2
Colla, S.3
Stewart, J.P.4
Hanamura, I.5
Gupta, S.6
-
23
-
-
0036014969
-
The enigma of ectopic expression of FGFR3 in multiple myeloma: A critical initiating event or just a target for mutational activation during tumor progression
-
Chesi M, Bergsagel PL, Kuehl WM. The enigma of ectopic expression of FGFR3 in multiple myeloma: a critical initiating event or just a target for mutational activation during tumor progression. Curr Opin Hematol 2002;9:288-93.
-
(2002)
Curr Opin Hematol
, vol.9
, pp. 288-293
-
-
Chesi, M.1
Bergsagel, P.L.2
Kuehl, W.M.3
-
24
-
-
0032212243
-
The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts
-
Chesi M, Nardini E, Lim RS, Smith KD, Kuehl WM, Bergsagel PL. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts. Blood 1998;92:3025-34.
-
(1998)
Blood
, vol.92
, pp. 3025-3034
-
-
Chesi, M.1
Nardini, E.2
Lim, R.S.3
Smith, K.D.4
Kuehl, W.M.5
Bergsagel, P.L.6
-
25
-
-
0033887241
-
Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription-polymerase chain reaction analysis of IGH-MMSET fusion transcripts
-
Malgeri U, Baldini L, Perfetti V, Fabris S, Vignarelli MC, Colombo G, et al. Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription-polymerase chain reaction analysis of IGH-MMSET fusion transcripts. Cancer Res 2000;60:4058-61.
-
(2000)
Cancer Res
, vol.60
, pp. 4058-4061
-
-
Malgeri, U.1
Baldini, L.2
Perfetti, V.3
Fabris, S.4
Vignarelli, M.C.5
Colombo, G.6
-
26
-
-
39749106551
-
Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells
-
Evans R, Naber C, Steffler T, Checkland T, Keats J, Maxwell C, et al. Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells. Leuk Lymphoma 2008;49:559-69.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 559-569
-
-
Evans, R.1
Naber, C.2
Steffler, T.3
Checkland, T.4
Keats, J.5
Maxwell, C.6
-
27
-
-
3843103732
-
Caspase-1zeta, a new splice variant of the caspase-1 gene
-
Feng Q, Li P, Leung PC, Auersperg N. Caspase-1zeta, a new splice variant of the caspase-1 gene. Genomics 2004;84:587-91.
-
(2004)
Genomics
, vol.84
, pp. 587-591
-
-
Feng, Q.1
Li, P.2
Leung, P.C.3
Auersperg, N.4
-
28
-
-
0029078965
-
Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases
-
Kamens J, Paskind M, Hugunin M, Talanian RV, Allen H, Banach D, et al. Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases. J Biol Chem 1995;270:15250-6.
-
(1995)
J Biol Chem
, vol.270
, pp. 15250-15256
-
-
Kamens, J.1
Paskind, M.2
Hugunin, M.3
Talanian, R.V.4
Allen, H.5
Banach, D.6
-
29
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999;96:857-68.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
-
30
-
-
2342628539
-
Phosphoinositide 3-kinase and Forkhead, a switch for cell division
-
Martinez-Gac L, Alvarez B, Garcia Z, Marques M, Arrizabalaga M, Carrera AC. Phosphoinositide 3-kinase and Forkhead, a switch for cell division. Biochem Soc Trans 2004;32(Pt 2):360-1.
-
(2004)
Biochem Soc Trans
, vol.32
, Issue.PART 2
, pp. 360-361
-
-
Martinez-Gac, L.1
Alvarez, B.2
Garcia, Z.3
Marques, M.4
Arrizabalaga, M.5
Carrera, A.C.6
-
31
-
-
0037031828
-
Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization
-
Tran NL, Adams DG, Vaillancourt RR, Heimark RL. Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization. J Biol Chem 2002;277:32905-14.
-
(2002)
J Biol Chem
, vol.277
, pp. 32905-32914
-
-
Tran, N.L.1
Adams, D.G.2
Vaillancourt, R.R.3
Heimark, R.L.4
-
32
-
-
34447134867
-
Targeting the phosphatidylinositol 3-kinase pathway in multiple myeloma
-
Younes H, Leleu X, Hatjiharissi E, Moreau AS, Hideshima T, Richardson P, et al. Targeting the phosphatidylinositol 3-kinase pathway in multiple myeloma. Clin Cancer Res 2007;13:3771-5.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3771-3775
-
-
Younes, H.1
Leleu, X.2
Hatjiharissi, E.3
Moreau, A.S.4
Hideshima, T.5
Richardson, P.6
-
33
-
-
33645745595
-
ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin
-
Karadag A, Zhou M, Croucher PI. ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin. Blood 2006;107:3271-8.
-
(2006)
Blood
, vol.107
, pp. 3271-3278
-
-
Karadag, A.1
Zhou, M.2
Croucher, P.I.3
-
34
-
-
0034811643
-
MDC-9 (ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin
-
Zhou M, Graham R, Russell G, Croucher PI. MDC-9 (ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin. Biochem Biophys Res Commun 2001;280:574-80.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 574-580
-
-
Zhou, M.1
Graham, R.2
Russell, G.3
Croucher, P.I.4
-
35
-
-
34047099312
-
Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes
-
Brennan D, Hu Y, Joubeh S, Choi YW, Whitaker-Menezes D, O'Brien T, et al. Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes. J Cell Sci 2007;120:758-71.
-
(2007)
J Cell Sci
, vol.120
, pp. 758-771
-
-
Brennan, D.1
Hu, Y.2
Joubeh, S.3
Choi, Y.W.4
Whitaker-Menezes, D.5
O'Brien, T.6
-
36
-
-
0032520775
-
The A-Myb transcription factor is a marker of centroblasts in vivo
-
Golay J, Broccoli V, Lamorte G, Bifulco C, Parravicini C, Pizzey A, et al. The A-Myb transcription factor is a marker of centroblasts in vivo. J Immunol 1998;160:2786-93.
-
(1998)
J Immunol
, vol.160
, pp. 2786-2793
-
-
Golay, J.1
Broccoli, V.2
Lamorte, G.3
Bifulco, C.4
Parravicini, C.5
Pizzey, A.6
-
37
-
-
0033767214
-
Role of INTERLEUKIN-6 in the pathogenesis of multiple myeloma
-
Gado K, Domjan G, Hegyesi H, Falus A. Role of INTERLEUKIN-6 in the pathogenesis of multiple myeloma. Cell Biol Int 2000;24:195-209.
-
(2000)
Cell Biol Int
, vol.24
, pp. 195-209
-
-
Gado, K.1
Domjan, G.2
Hegyesi, H.3
Falus, A.4
-
38
-
-
10544241191
-
Interleukin-10 is a growth factor for human myeloma cells by induction of an oncostatin M autocrine loop
-
Gu ZJ, Costes V, Lu ZY, Zhang XG, Pitard V, Moreau JF, et al. Interleukin-10 is a growth factor for human myeloma cells by induction of an oncostatin M autocrine loop. Blood 1996;88:3972-86.
-
(1996)
Blood
, vol.88
, pp. 3972-3986
-
-
Gu, Z.J.1
Costes, V.2
Lu, Z.Y.3
Zhang, X.G.4
Pitard, V.5
Moreau, J.F.6
|