Regulation of endobiotics glucuronidation by ligand-activated transcription factors: Physiological function and therapeutic potential

Drug Metabolism Reviews

Volumn 42, Issue 1, 2010, Pages 110-122

  Verreault, Mélanie ^a   Kaeding, Jenny ^a   Caron, Patrick ^a   Trottier, Jocelyn ^a   Grosse, Laurent ^a   Houssin, Élise ^a   Pâquet, Sophie ^a   Perreault, Martin ^a   Barbier, Olivier ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Androgen receptor (AR); Androgens; Aryl hydrocarbon receptor (AhR); Bile acids; Bilirubin; Constitutive androstane receptor (CAR); Farnesoid X receptor(FXR); Peroxisome proliferator activated receptor (PPARa); Pregnane X receptor (PXR)

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BILE ACID; BILIRUBIN; CONSTITUTIVE ANDROSTANE RECEPTOR; FARNESOID X RECEPTOR; GLUCURONOSYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PREGNANE X RECEPTOR; TRANSCRIPTION FACTOR;

BILIRUBIN METABOLISM; CANCER INHIBITION; CRIGLER NAJJAR SYNDROME; ENZYME REGULATION; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GLUCURONIDATION; HUMAN; LIGAND BINDING; LIVER METABOLISM; NONHUMAN; REVIEW; TRANSCRIPTION REGULATION;

EID: 74549174924     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602530903219220     Document Type: Review

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