Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice

Hepatology

Volumn 41, Issue 3, 2005, Pages 497-505

  Saini, Simrat P S ^a,b   Mu, Ying ^a,b   Gong, Haibiao ^a,b   Toma, David ^a,b   Uppal, Hirdesh ^a,b,c   Ren, Songrong ^a,b   Li, Song ^a,b   Poloyac, Samuel M ^b   Xie, Wen ^a,b,c,d  

^a Center for Pharmacogenetics   (United States)

^b School of Pharmacy   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2B; CYTOCHROME P450 2B10; CYTOCHROME P450 3A; CYTOCHROME P450 3A11; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER; PREGNANE X RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BILIRUBIN METABOLISM; DETOXIFICATION; ENZYME ACTIVITY; GENE CONTROL; HYPERBILIRUBINEMIA; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LIVER CLEARANCE; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BILIRUBIN; CELLS, CULTURED; CYTOCHROME P-450 CYP3A; HOMEOSTASIS; MICE; MICE, INBRED C57BL; OXIDOREDUCTASES, N-DEMETHYLATING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; TRANSCRIPTION FACTORS;

EID: 14244251458     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20570     Document Type: Article

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