FXR induces the UGT2B4 enzyme in hepatocytes: A potential mechanism of negative feedback control of FXR activity

Gastroenterology

Volumn 124, Issue 7, 2003, Pages 1926-1940

  Barbier, Olivier ^a   Torra, Ines Pineda ^a   Sirvent, Audrey ^b   Claudel, Thierry ^a   Blanquart, Christophe ^a   Duran Sandoval, Daniel ^a   Kuipers, Folkert ^c   Kosykh, Vladimir ^d   Fruchart, Jean Charles ^a   Staels, Bart ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

^b Genfit SA   (France)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d INSTITUTE OF EXPERIMENTAL CARDIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; CHENODEOXYCHOLIC ACID; FARNESOID X RECEPTOR; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; MESSENGER RNA; RETINOID X RECEPTOR; UNCLASSIFIED DRUG; URIDINE 5' DIPHOSPHATE GLUCURONYLTRANSFERASE 2B4; VITAMIN;

ARTICLE; BILE ACID SYNTHESIS; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE OVEREXPRESSION; GENE TARGETING; GLUCURONIDATION; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; IMMUNOPRECIPITATION; INTESTINE ABSORPTION; LIPID ABSORPTION; LIVER CELL; NEGATIVE FEEDBACK; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR BINDING; RECEPTOR UPREGULATION; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

EID: 0038281429     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(03)00388-3     Document Type: Article

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