Induction of human UGT1A1 by bilirubin through AhR dependent pathway

Drug Metabolism Letters

Volumn 2, Issue 4, 2008, Pages 231-237

  Togawa, Hiroshi ^a   Shinkai, Shigeko ^a   Mizutani, Takaharu ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Aryl hydrocarbon receptor; Bilirubin; UDP glucuronosyltransferase; UGT1A1; Xenobiotic responsive element

Indexed keywords

ALPHA NAPHTHOFLAVONE; AROMATIC HYDROCARBON RECEPTOR; BILIRUBIN; GLUCURONOSYLTRANSFERASE 1A1; MESSENGER RNA; BILIRUBIN URIDINE DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; BILIRUBIN URIDINE-DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE; LIGAND;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA STRUCTURE; ENZYME INDUCTION; ENZYME REGULATION; GENE DELETION; GENE EXPRESSION; GENE LOCATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BINDING; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; XENOBIOTIC RESPONSIVE ELEMENT; ADULT; GENETICS; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; NEWBORN; PROTEIN BINDING; TUMOR CELL LINE;

ADULT; BILIRUBIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; ENZYME INDUCTION; GENES, REPORTER; GLUCURONOSYLTRANSFERASE; HUMANS; INFANT, NEWBORN; LIGANDS; LIVER NEOPLASMS; PROTEIN BINDING; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 65249140467     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231208786734120     Document Type: Article

References (43)

1. Evans, W.E.; Relling, M.V. Science, 1999, 286, 487.
2. King, C.; Finley, B.; Franklin, R. Drug Metab. Dispos., 2000, 28, 661.
3. Radominska-Pandya, A.; Czernik, P.J.; Little, J.M.; Battaglia, E.; Mackenzie, P.I. Drug Metab. Rev., 1999, 31, 817.
4. Fisher, M.B.; Paine, M.F.; Strelevitz, T.J.; Wrighton, S.A. Drug Metab. Rev., 2001, 33, 273.
5. Vanstapel, F.; Blanckaert, N. Arch. Biochem. Biophys., 1988, 263, 216.
6. Yokota, H.; Yuasa, A.; Sato, R. J. Biochem., 1992, 112, 192.
7. Fevery, J.; van der Vijver, M.; Michiels, R.; Heierwegh, K.P.M. Biochem. J., 1977, 164, 737.
8. Tukey, R.H.; Strassburg, C.P. Mol. Pharmcol., 2001, 59, 405
9. Peters, W.H.M.; Jansen, P.L.M.; Nauta, H.M. J. Biol. Chem., 1984, 259, 11791
10. Sato, H.; Koiwai, O.; Tanabe, K.; Kashiwamata, S. Biochem. Biophys. Res. Commun., 1990, 169, 260.
11. Oguri, K. Xenobio. Metab. Dispos., 2000, 15, 136.
12. Gong, Q.H.; Cho, J.W.; Huang, T.; Potter, C.; Gholami, N.; Basu, N.K.; Kubota, S.; Carvalho, S.; Pennington, M.W.; Owens, I.S.; Popescu, N.C. Pharmacogenetics, 2001, 11, 357.
13. Ueyama, H.; Koiwai, O.; Soeda, Y.; Sato, H.; Satoh, Y.; Ohkubo, I.; Doida, Y. Hepatology Res., 1997, 9, 152.
14. Sugatani, J.; Kojima, H.; Ueda, A.; Kakizaki, S.; Yoshinari, K.; Gong, Q.H.; Owens, I.S.; Negishi, M.; Sueyoshi, T. Hepatology, 2001, 33, 1232.
15. Sugatani, J.; Nishitani, S.; Yamakawa, K.; Yoshitani, K.; Sueyoshi, T.; Negishi, M.; Miwa, M. Mol. Pharmacol., 2005, 67, 845.
16. Honkakoski, P.; Moore, R.; Washburn, K.A.; Negishi, M. Mol. Pharmacol., 1998, 53, 597.
17. Sueyoshi, T.; Kawamoto, T.; Zelko, I.; Honkakoski, P.; Negishi, M. J. Biol. Chem., 1999, 274, 6043.
18. Yueh, M.F.; Huang, Y.H.; Chen, S.; Nguyen, N.; Tukey, R.H. J. Biol. Chem., 2003, 278, 15001.
19. Xie, W.; Yueh, M.F.; Radominska-Pandya, A.; Saini, S.P.; Negishi, M.; Bottroff, B.S.; Cabrera, G.Y.; Tukey, R.H.; Evans, R.M. Pro. Natl. Acad. Sci. USA, 2003, 100, 4150.
20. Huss, J.M.; Kasper, C.B. Mol. Pharmacol., 2000, 58, 48.
21. Bock, K.W.; Gschaidmeir, H.; Heel, H.; Lehmkoster, T.; Munzel, P.A.; Bock-Hennig, B.S. Drug Metab. Rev., 1999, 31, 411.
22. Auyeung, D.J.; Kessler, F.K.; Ritter, J.K. Mol. Pharmacol., 2003, 63, 119.
23. Huang, W.; Zhang, J.; Chua, S.S.; Qayanani, M.; Han, Y.; Granata, R.; Moore, D.D. Proc. Natl. Acad. Sci. USA, 2003, 100, 4156.
24. Sugatani, J.; Yamakawa, K.; Yoshinari, K.; Machida, T.; Takagi, H.; Mor, M.; Kakizaki, S.; Sueyoshi, T.; Negishi, M.; Miwa, M. Biochem. Biophy. Res. Commun., 2002, 292, 492.
25. Bosma, P.J.; Chowdhury, J.R.; Bakker, C. N. Eng. J. Med., 1995, 333, 1171.
26. Monaghan, G.; Ryan, M.; Seddon, R.; Hume, R.; Burchell, B. Lancet, 1996, 347, 578.
27. Sato, H.; Adach, Y.; Koiwai, O. Lancet, 1996, 347, 557.
28. Koiwai, O.; Aono, S.; Adachi, Y.; Kamisaka, T.; Yasui, Y.; Nishizawa, M.; Sato, H. Hum. Mol. Genet., 1996, 5, 645.
29. Usui, T.; Kuno, T.; Ueyama, H.; Ohkubo, I.; Mizutani, T. Biochem. Pharmacol., 2006, 71, 693.
30. Kuno, T.; Togawa, H.; Mizutani, T. Mol. Biol. Reports In Press (PMID 17530442).
31. Phelan, D.; Winter, G.M.; Rogers, W..; Lam, J.C.; Denison, M.S. Arch. Biochem. Biophys., 1998, 357, 155.
32. Bussmann, U.A.; Baranao, J.L. Biol. Reprod., 2006, 75, 360
33. Spink, D.C.;.Katz, B.H.; Hussain, M.M.;.Pentecost, B.T.; Zhimin, C.Z.; Spink, B.C. Carcinogenesis, 2003, 24, 1941.
34. Mortensen, A.S.; Arukwe, A. Comp. Hepatol., 2007, 6, 2.
35. Liu, S.; Abdelrahim,M.; Khan, S.; Ariazi, E.; Jordan,V.C.; Safe, S. Biol. Chem., 2006, 387: 1209
36. Matthews, J.; Wihlén, B.; Thomsen, J.; Gustafsson, J.A. Mol. Cell. Biol., 2005, 25, 5317.
37. Patel, R.D.; Hollingshead, B.D.; Omiecinski, C.J.; Perdew, G.H. Hepatology, 2007, 46, 209
38. Jung, D.; Mangelsdorf, D.J.; Meyer, U.A. J. Biol. Chem., 2006, 281, 19081.
39. Fujiwara, R.; Nakajima, M.; Yamanaka, H.; Katoh, M.; Yokoi, T. Drug Metab. Dispos., 2007, 35, 1781.
40. Theresa, N.; Robert, O.; Tukey, H. J. Biol. Chem., 2007, 282, 4821.
41. Matern, H.; Matern, S.; Gerok, W. J. Biol. Chem., 1982, 257, 7422.
42. Ghosh, S.S.; Sappal, B.S.; Kalpana, G.V.; Lee, S.W. J. Biol. Chem., 2001, 276, 42108.
43. Gschaidmeier, H.; Bock, K.W. Biochem. Pharmacol., 1994, 48, 1545.