Phase II enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells

Toxicology in Vitro

Volumn 21, Issue 8, 2007, Pages 1592-1602

  Westerink, Walter M A ^a   Schoonen, Willem G E J ^a  

^a NV Organon ^*  (Netherlands)

Author keywords

Cytotoxicity; Hepatocytes; HepG2; Induction studies; Phase II metabolism

Indexed keywords

ACYLTRANSFERASE; AROMATIC HYDROCARBON RECEPTOR; EPOXIDE HYDROLASE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; PREGNANE X RECEPTOR; SULFOTRANSFERASE;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; CRYOPRESERVATION; CYTOTOXICITY; ENZYME ANALYSIS; ENZYME INDUCTION; ENZYME REGULATION; HUMAN; HUMAN CELL; LIVER CELL; POLYMERASE CHAIN REACTION; UPREGULATION;

AGED; CELL LINE; CRYOPRESERVATION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HEPATOCYTES; HUMANS; MALE; METABOLIC DETOXICATION, PHASE II; MIDDLE AGED; RNA, MESSENGER;

EID: 36148949386     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.06.017     Document Type: Article

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