-
1
-
-
0030878076
-
Modulation of thrombin's procoagulant and anticoagulant properties
-
Leung L.L., Lawrence L., Gibbs C. Modulation of thrombin's procoagulant and anticoagulant properties. Thromb Haemost 1997, 78:577-580.
-
(1997)
Thromb Haemost
, vol.78
, pp. 577-580
-
-
Leung, L.L.1
Lawrence, L.2
Gibbs, C.3
-
2
-
-
84884743314
-
Acquired vitamin K-dependent carboxylation defi ciency in liver disease
-
Blanchard R.A., Furie B.C., Jorgensen J.J., et al. Acquired vitamin K-dependent carboxylation defi ciency in liver disease. Proc Natl Acad Sci USA 1981, 76:491.
-
(1981)
Proc Natl Acad Sci USA
, vol.76
, pp. 491
-
-
Blanchard, R.A.1
Furie, B.C.2
Jorgensen, J.J.3
-
3
-
-
0023924910
-
Cofactor proteins in the assembly and expression of blood clotting enzyme couples
-
Mann K.G., Jenny R.J., Krishnaswamy S. Cofactor proteins in the assembly and expression of blood clotting enzyme couples. Ann Intern Med 1984, 57:915.
-
(1984)
Ann Intern Med
, vol.57
, pp. 915
-
-
Mann, K.G.1
Jenny, R.J.2
Krishnaswamy, S.3
-
4
-
-
0018907213
-
The role of phospholipids and factor Va in the prothrombinase complex
-
Rosing J., Tans G., Govers-Riemslag J.W.P., et al. The role of phospholipids and factor Va in the prothrombinase complex. J Biol Chem 1980, 255:274.
-
(1980)
J Biol Chem
, vol.255
, pp. 274
-
-
Rosing, J.1
Tans, G.2
Govers-Riemslag, J.W.P.3
-
5
-
-
37049178293
-
Evolution of proteolytic enzymes
-
Neurath H. Evolution of proteolytic enzymes. Science 1984, 224:350-357.
-
(1984)
Science
, vol.224
, pp. 350-357
-
-
Neurath, H.1
-
6
-
-
0025346345
-
Design and characterization of Hirulogs: A novel class of bivalent peptide inhibitors of thrombin
-
Maraganore J.M., Bourdon P., Jablonski J., Ramachandran K., Fenton J.W. Design and characterization of Hirulogs: A novel class of bivalent peptide inhibitors of thrombin. Biochemistry 1990, 29:7095-7101.
-
(1990)
Biochemistry
, vol.29
, pp. 7095-7101
-
-
Maraganore, J.M.1
Bourdon, P.2
Jablonski, J.3
Ramachandran, K.4
Fenton, J.W.5
-
7
-
-
0014221653
-
Structure of N-terminal fragments of fibrinogen and specificity of thrombin
-
Blomback B., Blomback M., Hessel B., et al. Structure of N-terminal fragments of fibrinogen and specificity of thrombin. Nature 1967, 215:1445.
-
(1967)
Nature
, vol.215
, pp. 1445
-
-
Blomback, B.1
Blomback, M.2
Hessel, B.3
-
8
-
-
0017764088
-
New fl uorogenic substrates for α-thrombin, factor Xa, kallikreins and urokinase
-
Morita T., Kato H., Iwanaga S., et al. New fl uorogenic substrates for α-thrombin, factor Xa, kallikreins and urokinase. J Biol Chem 1977, 82:1495.
-
(1977)
J Biol Chem
, vol.82
, pp. 1495
-
-
Morita, T.1
Kato, H.2
Iwanaga, S.3
-
9
-
-
0006144247
-
The action of thrombin on synthetic substrates
-
Sherry S., Troll W. The action of thrombin on synthetic substrates. J Biol Chem 1954, 208:95.
-
(1954)
J Biol Chem
, vol.208
, pp. 95
-
-
Sherry, S.1
Troll, W.2
-
10
-
-
1842408993
-
Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII)
-
Pittman D., Kaufman R. Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII). Proc Natl Acad Sci USA 1988, 85:2429.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 2429
-
-
Pittman, D.1
Kaufman, R.2
-
11
-
-
0018412614
-
Thrombin-catalyzed activation of single-chain bovine factor V
-
Nesheim M.E., Mann K.G. Thrombin-catalyzed activation of single-chain bovine factor V. J Biol Chem 1979, 254:10952.
-
(1979)
J Biol Chem
, vol.254
, pp. 10952
-
-
Nesheim, M.E.1
Mann, K.G.2
-
12
-
-
84884801430
-
The subunit structure of thrombinactivated factor V: Isolation of activated factor V, separation of subunits and reconstitution of biological activity
-
Esmon C.T. The subunit structure of thrombinactivated factor V: Isolation of activated factor V, separation of subunits and reconstitution of biological activity. J Biol Chem 1979, 1979:254.
-
(1979)
J Biol Chem
, vol.1979
, pp. 254
-
-
Esmon, C.T.1
-
13
-
-
0015935236
-
Human factor XIII from plasma and platelets
-
Schwartz M.L., Pizzo S.V., Hill R.L., et al. Human factor XIII from plasma and platelets. J Biol Chem 1973, 248:1395.
-
(1973)
J Biol Chem
, vol.248
, pp. 1395
-
-
Schwartz, M.L.1
Pizzo, S.V.2
Hill, R.L.3
-
14
-
-
0014555003
-
Binding of thrombin to antithrombin III
-
Abildgaard U. Binding of thrombin to antithrombin III. Scand J Clin Lab Invest 1969, 24:89.
-
(1969)
Scand J Clin Lab Invest
, vol.24
, pp. 89
-
-
Abildgaard, U.1
-
16
-
-
0018101159
-
Comparison of the inhibition of thrombin by three plasma protease inhibitors
-
Downing M.R., Bloom J.W., Mann K.G. Comparison of the inhibition of thrombin by three plasma protease inhibitors. Biochemistry 1978, 17:2649.
-
(1978)
Biochemistry
, vol.17
, pp. 2649
-
-
Downing, M.R.1
Bloom, J.W.2
Mann, K.G.3
-
17
-
-
0017107524
-
Inactivation of human thrombin in the presence of human α1-proteinase inhibitor
-
Matheson N.R., Travis J. Inactivation of human thrombin in the presence of human α1-proteinase inhibitor. Biochem J 1976, 159:495.
-
(1976)
Biochem J
, vol.159
, pp. 495
-
-
Matheson, N.R.1
Travis, J.2
-
18
-
-
0029112841
-
Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface
-
Esmon C.T. Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface. FASEB J 1995, 9:946-955.
-
(1995)
FASEB J
, vol.9
, pp. 946-955
-
-
Esmon, C.T.1
-
19
-
-
0029014036
-
An allosteric switch controls the procoagulant and anticoagulant activities of thrombin
-
Dang Q., Vindigni A., DiCera E. An allosteric switch controls the procoagulant and anticoagulant activities of thrombin. Proc Natl Acad Sci USA 1995, 92:5977-5981.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5977-5981
-
-
Dang, Q.1
Vindigni, A.2
DiCera, E.3
-
20
-
-
0017182955
-
The measurement of thrombin in clotting blood by radioimmunoassay
-
Shuman M.A. The measurement of thrombin in clotting blood by radioimmunoassay. J Clin Invest 1976, 58:1249-1258.
-
(1976)
J Clin Invest
, vol.58
, pp. 1249-1258
-
-
Shuman, M.A.1
-
21
-
-
0024457599
-
Binding of thrombin to subendothelial extracellular matrix: Protection and expression of functional properties
-
Bar-Shavit R., Eldor A., Vlodavsky I. Binding of thrombin to subendothelial extracellular matrix: Protection and expression of functional properties. J Clin Invest 1989, 84:1096-1104.
-
(1989)
J Clin Invest
, vol.84
, pp. 1096-1104
-
-
Bar-Shavit, R.1
Eldor, A.2
Vlodavsky, I.3
-
22
-
-
0024411829
-
Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury
-
Eidt J., Allison P., Nobel S., et al. Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury. J Clin Invest 1989, 84:18-27.
-
(1989)
J Clin Invest
, vol.84
, pp. 18-27
-
-
Eidt, J.1
Allison, P.2
Nobel, S.3
-
23
-
-
0024393955
-
Role of thrombin and thromboxane A2 in reocclusion following coronary thrombolysis
-
Fitzgerald D., Fitzgerald G. Role of thrombin and thromboxane A2 in reocclusion following coronary thrombolysis. Proc Natl Acad Sci USA 1989, 86:7585-7589.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7585-7589
-
-
Fitzgerald, D.1
Fitzgerald, G.2
-
24
-
-
0001484909
-
Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin PPACK
-
Hansen S., Harker L.A. Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin PPACK. Proc Natl Acad Sci USA 1988, 85:3184-3188.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 3184-3188
-
-
Hansen, S.1
Harker, L.A.2
-
25
-
-
0024582671
-
Effects of thrombin inhibition on the development of acute platelet-thrombus deposition during angioplasty in pigs: Heparin versus hirudin, a specific thrombin inhibitor
-
Heras M., Chesebro J., Penny W., Bailey K., Badimon L., Fuster V. Effects of thrombin inhibition on the development of acute platelet-thrombus deposition during angioplasty in pigs: Heparin versus hirudin, a specific thrombin inhibitor. Circulation 1989, 79:657-665.
-
(1989)
Circulation
, vol.79
, pp. 657-665
-
-
Heras, M.1
Chesebro, J.2
Penny, W.3
Bailey, K.4
Badimon, L.5
Fuster, V.6
-
26
-
-
0025017743
-
Prevention of platelet-rich arterial thrombosis by selective thrombin inhibition
-
Jang I.-K., Gold H.K., Ziskind A.A., et al. Prevention of platelet-rich arterial thrombosis by selective thrombin inhibition. Circulation 1989, 81:219-225.
-
(1989)
Circulation
, vol.81
, pp. 219-225
-
-
Jang, I.-K.1
Gold, H.K.2
Ziskind, A.A.3
-
27
-
-
0014191175
-
Actions of thrombin and other coagulant and proteolytic enzymes on blood platelets
-
Davey M., Luscher E. Actions of thrombin and other coagulant and proteolytic enzymes on blood platelets. Nature 1967, 216:857-858.
-
(1967)
Nature
, vol.216
, pp. 857-858
-
-
Davey, M.1
Luscher, E.2
-
28
-
-
0002906957
-
Platelet membrane proteins: Composition and receptor function
-
Elsevier/North Holland Biomedical Press, New York, J.L. Gordon (Ed.)
-
Berndt M., Phillips D. Platelet membrane proteins: Composition and receptor function. Platelets in biology and pathology 1981, 43-74. Elsevier/North Holland Biomedical Press, New York. J.L. Gordon (Ed.).
-
(1981)
Platelets in biology and pathology
, pp. 43-74
-
-
Berndt, M.1
Phillips, D.2
-
29
-
-
0022221113
-
A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation
-
Stenberg P.E., McEver R.P., Shuman M.A., Jacques Y.V., Bainton D.F. A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J Cell Biol 1985, 101:880-886.
-
(1985)
J Cell Biol
, vol.101
, pp. 880-886
-
-
Stenberg, P.E.1
McEver, R.P.2
Shuman, M.A.3
Jacques, Y.V.4
Bainton, D.F.5
-
30
-
-
0032484987
-
CD40 ligand on activated platelets triggers an infl ammatory reaction of endothelial cells
-
Henn V., et al. CD40 ligand on activated platelets triggers an infl ammatory reaction of endothelial cells. Nature 1998, 391:591-594.
-
(1998)
Nature
, vol.391
, pp. 591-594
-
-
Henn, V.1
-
31
-
-
0032168738
-
Integrin affinity modulation
-
Hughes P.E., Pfaff M. Integrin affinity modulation. Trends Cell Biol 1998, 8:359-364.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 359-364
-
-
Hughes, P.E.1
Pfaff, M.2
-
32
-
-
0026661585
-
Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor
-
Savage B., Shattil S., Ruggeri Z.M. Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor. J Biol Chem 1992, 267:11300-11306.
-
(1992)
J Biol Chem
, vol.267
, pp. 11300-11306
-
-
Savage, B.1
Shattil, S.2
Ruggeri, Z.M.3
-
33
-
-
4243156558
-
Stimulation of endothelial cell prostacyclin production by thrombin trypsin, and the ionophore A23187
-
Weksler B., Ley C., Jaffe E.A. Stimulation of endothelial cell prostacyclin production by thrombin trypsin, and the ionophore A23187. Ann NY Acad Sci 1986, 485:349-368.
-
(1986)
Ann NY Acad Sci
, vol.485
, pp. 349-368
-
-
Weksler, B.1
Ley, C.2
Jaffe, E.A.3
-
34
-
-
84884782922
-
Human endothelial cells in culture produce platelet-activating factor when stimulated by thrombin
-
Prescott S., Zimmerman G., McIntyre T. Human endothelial cells in culture produce platelet-activating factor when stimulated by thrombin. Proc Natl Acad Sci USA 1979, 63:580-587.
-
(1979)
Proc Natl Acad Sci USA
, vol.63
, pp. 580-587
-
-
Prescott, S.1
Zimmerman, G.2
McIntyre, T.3
-
35
-
-
0026569242
-
Regulation of plateletactivating factor (PAF) synthesis and PAF-mediated neutrophil adhesion to endothelial cells activated by thrombin
-
Carveth H., Shaddy R., Whatley R., McIntyre T., Prescott S., Zimmerman G. Regulation of plateletactivating factor (PAF) synthesis and PAF-mediated neutrophil adhesion to endothelial cells activated by thrombin. Semin Thromb Hemost 1992, 18:126-134.
-
(1992)
Semin Thromb Hemost
, vol.18
, pp. 126-134
-
-
Carveth, H.1
Shaddy, R.2
Whatley, R.3
McIntyre, T.4
Prescott, S.5
Zimmerman, G.6
-
36
-
-
0026495386
-
Effect of endothelin on the release of tissue plasminogen activator and plasminogen activator inhibitor-1 from cultured human endothelial cells and interaction with thrombin
-
Yamamoto C., Kaji T., Sakamoto M., Koizumi F. Effect of endothelin on the release of tissue plasminogen activator and plasminogen activator inhibitor-1 from cultured human endothelial cells and interaction with thrombin. Thromb Res 1992, 67:619-624.
-
(1992)
Thromb Res
, vol.67
, pp. 619-624
-
-
Yamamoto, C.1
Kaji, T.2
Sakamoto, M.3
Koizumi, F.4
-
37
-
-
0023001143
-
Thrombin stimulates c-sis gene expression in microvascular endothelial cells
-
Daniel T., Gibbs V.C., Milfay D., et al. Thrombin stimulates c-sis gene expression in microvascular endothelial cells. J Biol Chem 1986, 261:9579-9582.
-
(1986)
J Biol Chem
, vol.261
, pp. 9579-9582
-
-
Daniel, T.1
Gibbs, V.C.2
Milfay, D.3
-
38
-
-
0024391784
-
Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140
-
Hattori R., Hamilton K.K., Fugate R.D., McEver R.P., Sims P.J. Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem 1989, 264:7768-7771.
-
(1989)
J Biol Chem
, vol.264
, pp. 7768-7771
-
-
Hattori, R.1
Hamilton, K.K.2
Fugate, R.D.3
McEver, R.P.4
Sims, P.J.5
-
39
-
-
0022924101
-
Thrombin stimulates neutrophil adherence by an endothelial cell-dependent mechanism
-
Zimmerman G., McIntyre T., Prescott S.M. Thrombin stimulates neutrophil adherence by an endothelial cell-dependent mechanism. Ann NY Acad Sci 1986, 485:349-368.
-
(1986)
Ann NY Acad Sci
, vol.485
, pp. 349-368
-
-
Zimmerman, G.1
McIntyre, T.2
Prescott, S.M.3
-
40
-
-
0021736924
-
Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells
-
Levin E.G., Marzec U., Anderson J., Harker L.A. Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells. J Clin Invest 1984, 74:1988-1995.
-
(1984)
J Clin Invest
, vol.74
, pp. 1988-1995
-
-
Levin, E.G.1
Marzec, U.2
Anderson, J.3
Harker, L.A.4
-
41
-
-
0022977918
-
Specificity of the thrombin-induced release of tissue plasminogen activator from cultured human endothelial cells
-
Levin E.G., Stern D.M., Nawroth P.P., Marlar R.A., Fair D.S., Fenton J.W., Harker L.A. Specificity of the thrombin-induced release of tissue plasminogen activator from cultured human endothelial cells. Thromb Haemost 1986, 56:115-119.
-
(1986)
Thromb Haemost
, vol.56
, pp. 115-119
-
-
Levin, E.G.1
Stern, D.M.2
Nawroth, P.P.3
Marlar, R.A.4
Fair, D.S.5
Fenton, J.W.6
Harker, L.A.7
-
42
-
-
0024327860
-
Thrombin regulation of mRNA levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells
-
Dichek D., Quertermous T. Thrombin regulation of mRNA levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells. Blood 1989, 74:222-228.
-
(1989)
Blood
, vol.74
, pp. 222-228
-
-
Dichek, D.1
Quertermous, T.2
-
43
-
-
0027368915
-
Involvement of the tethered ligand receptor in thrombin-induced entothelium-mediated relaxations
-
Tesfamariam B., Allen G., Normandin K., Antonaccio M. Involvement of the tethered ligand receptor in thrombin-induced entothelium-mediated relaxations. Am Physiol Cell Physiol 1993, 265:1744-1749.
-
(1993)
Am Physiol Cell Physiol
, vol.265
, pp. 1744-1749
-
-
Tesfamariam, B.1
Allen, G.2
Normandin, K.3
Antonaccio, M.4
-
44
-
-
0028121374
-
Regulation of vascular endothelial barrier function
-
Lum H., Malik A.B. Regulation of vascular endothelial barrier function. Am Physiol Cell Physiol 1994, 267:1223-1241.
-
(1994)
Am Physiol Cell Physiol
, vol.267
, pp. 1223-1241
-
-
Lum, H.1
Malik, A.B.2
-
45
-
-
0026655624
-
Modulation of vascular endothelial permeability by thrombin
-
DeMichele M., Minnear F. Modulation of vascular endothelial permeability by thrombin. Semin Thromb Hemost 1992, 18:287-295.
-
(1992)
Semin Thromb Hemost
, vol.18
, pp. 287-295
-
-
DeMichele, M.1
Minnear, F.2
-
46
-
-
0031681419
-
Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation
-
Naldini A., Sower L., Bocci V., Meyers B., Carney D. Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation. J Cell Pathol 1998, 177:76-84.
-
(1998)
J Cell Pathol
, vol.177
, pp. 76-84
-
-
Naldini, A.1
Sower, L.2
Bocci, V.3
Meyers, B.4
Carney, D.5
-
47
-
-
0026705071
-
A role for α-thrombin in polymorphonuclear leukocyte recruitment during infl ammation
-
Drake W., Issekut A. A role for α-thrombin in polymorphonuclear leukocyte recruitment during infl ammation. Thromb Haemost 1992, 18:333-340.
-
(1992)
Thromb Haemost
, vol.18
, pp. 333-340
-
-
Drake, W.1
Issekut, A.2
-
48
-
-
0031157455
-
Thrombin induces endothelial-type II activation in vitro: IL-1 and TNF-xindependent IL-8 secretion and E-selectin expression
-
Kaplanski G., Fabrigoule M., Boulay V., Dinarello C., Bongrand P., Farnarier C. Thrombin induces endothelial-type II activation in vitro: IL-1 and TNF-xindependent IL-8 secretion and E-selectin expression. J Immunol 1997, 158:5435-5441.
-
(1997)
J Immunol
, vol.158
, pp. 5435-5441
-
-
Kaplanski, G.1
Fabrigoule, M.2
Boulay, V.3
Dinarello, C.4
Bongrand, P.5
Farnarier, C.6
-
49
-
-
0022470963
-
Thrombin-induced chemotaxis and aggregation of neutrophils
-
Bizios R., Lai L., Fenton J., Malik A.B. Thrombin-induced chemotaxis and aggregation of neutrophils. J Cell Physiol 1986, 128:485-490.
-
(1986)
J Cell Physiol
, vol.128
, pp. 485-490
-
-
Bizios, R.1
Lai, L.2
Fenton, J.3
Malik, A.B.4
-
50
-
-
0022337475
-
Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro
-
Zimmerman G., McIntyre T., Prescott S. Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. J Clin Invest 1985, 76:2235-2246.
-
(1985)
J Clin Invest
, vol.76
, pp. 2235-2246
-
-
Zimmerman, G.1
McIntyre, T.2
Prescott, S.3
-
51
-
-
0032529677
-
Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106)
-
Kaplanski G., Marin V., Fabrigoule M., Boulay V., Benoliel A., Bongrand P., Kaplanski S., Farnarier C. Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106). Blood 1998, 92:1259-1267.
-
(1998)
Blood
, vol.92
, pp. 1259-1267
-
-
Kaplanski, G.1
Marin, V.2
Fabrigoule, M.3
Boulay, V.4
Benoliel, A.5
Bongrand, P.6
Kaplanski, S.7
Farnarier, C.8
-
52
-
-
0034283288
-
Thrombin: A neuronal cell modulator
-
Turgeon V., Salman N., Houenou L. Thrombin: A neuronal cell modulator. Thromb Res 2001, 99:417-427.
-
(2001)
Thromb Res
, vol.99
, pp. 417-427
-
-
Turgeon, V.1
Salman, N.2
Houenou, L.3
-
53
-
-
0032508557
-
Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from
-
Lourbakos A., Chinni C., Thompson P., Potempa J., Travis J., Mackie E., Pike R. Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from. Porphyromonas gingivalis. FEBS Lett 1998, 435:45-48.
-
(1998)
Porphyromonas gingivalis. FEBS Lett
, vol.435
, pp. 45-48
-
-
Lourbakos, A.1
Chinni, C.2
Thompson, P.3
Potempa, J.4
Travis, J.5
Mackie, E.6
Pike, R.7
-
54
-
-
0026684801
-
Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo
-
Nierodzik M., Kajumo F., Karpatkin S. Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo. Cancer Res 1992, 52:3267-3272.
-
(1992)
Cancer Res
, vol.52
, pp. 3267-3272
-
-
Nierodzik, M.1
Kajumo, F.2
Karpatkin, S.3
-
55
-
-
0027201786
-
Thrombin increases the metastatic potential of tumor cells
-
Wojtukiewicz M.Z., Tang D.G., Ciarelli J.J., Nelson K.K., Walz D.A., Diglio C.A., Mammen E.F., Honn K.V. Thrombin increases the metastatic potential of tumor cells. Int J Cancer 1993, 54:793-806.
-
(1993)
Int J Cancer
, vol.54
, pp. 793-806
-
-
Wojtukiewicz, M.Z.1
Tang, D.G.2
Ciarelli, J.J.3
Nelson, K.K.4
Walz, D.A.5
Diglio, C.A.6
Mammen, E.F.7
Honn, K.V.8
-
56
-
-
0026029064
-
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo
-
Nierodzik M.L., Plotkin A., Kajumo F., Kartpatkin S. Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo. J Clin Invest 1991, 87:299-336.
-
(1991)
J Clin Invest
, vol.87
, pp. 299-336
-
-
Nierodzik, M.L.1
Plotkin, A.2
Kajumo, F.3
Kartpatkin, S.4
-
57
-
-
0025903807
-
Thrombin modulates phosphoinositide metabolism, cytosolic calcium, and impulse initiation in the heart
-
Steinberg S., Robinson R., Lieberman H., Stern D., Rosen M. Thrombin modulates phosphoinositide metabolism, cytosolic calcium, and impulse initiation in the heart. Cir Res 1991, 68:1216-1229.
-
(1991)
Cir Res
, vol.68
, pp. 1216-1229
-
-
Steinberg, S.1
Robinson, R.2
Lieberman, H.3
Stern, D.4
Rosen, M.5
-
58
-
-
0030060695
-
Arrythmogenic action of thrombin during myocardial reperfusion via release of inositol 1,4,5-triphosphate
-
Jacobsen A., Du X., Lambert K., Dart A., Woodcock E. Arrythmogenic action of thrombin during myocardial reperfusion via release of inositol 1,4,5-triphosphate. Circulation 1996, 93:23-26.
-
(1996)
Circulation
, vol.93
, pp. 23-26
-
-
Jacobsen, A.1
Du, X.2
Lambert, K.3
Dart, A.4
Woodcock, E.5
-
59
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu T., Hung D., Wheaton V., Coughlin S. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991, 64:1057-1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.1
Hung, D.2
Wheaton, V.3
Coughlin, S.4
-
60
-
-
0025784847
-
CDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca mobilization
-
Rasmussen U.B., et al. cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca mobilization. FEBS Lett 1991, 288:123-128.
-
(1991)
FEBS Lett
, vol.288
, pp. 123-128
-
-
Rasmussen, U.B.1
-
61
-
-
0025812324
-
Model systems for the study of seven-transmembrane segment receptors
-
Dohlman H., Thorner J., Caron M., et al. Model systems for the study of seven-transmembrane segment receptors. Annu Rev Biochem 1992, 60:651-688.
-
(1992)
Annu Rev Biochem
, vol.60
, pp. 651-688
-
-
Dohlman, H.1
Thorner, J.2
Caron, M.3
-
62
-
-
0028364862
-
Thrombin receptor activation. Confi rmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode
-
Chen J., Ishii M., Wang L., Ishii K., Coughlin S.R. Thrombin receptor activation. Confi rmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode. J Biol Chem 1994, 269:16041-16045.
-
(1994)
J Biol Chem
, vol.269
, pp. 16041-16045
-
-
Chen, J.1
Ishii, M.2
Wang, L.3
Ishii, K.4
Coughlin, S.R.5
-
63
-
-
0030979972
-
Protease-activated receptor 3 is a second thrombin receptor in humans
-
Ishihara H., Connolly A., Zeng D., Kahn M.L., Zheng W., Timmons C., Tram T., Coughlin S.R. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 1997, 386:502-506.
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
Connolly, A.2
Zeng, D.3
Kahn, M.L.4
Zheng, W.5
Timmons, C.6
Tram, T.7
Coughlin, S.R.8
-
64
-
-
0032499696
-
Cloning and characterization of human proteaseactivated receptor 4
-
Xu W., Andersen H., Whitmore T.E., Presnell S.R., Yee D.P., Shing A., Gilbert T., Davie E.W., Foster D.C. Cloning and characterization of human proteaseactivated receptor 4. Proc Natl Acad Sci USA 1998, 95:6642-6646.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6642-6646
-
-
Xu, W.1
Andersen, H.2
Whitmore, T.E.3
Presnell, S.R.4
Yee, D.P.5
Shing, A.6
Gilbert, T.7
Davie, E.W.8
Foster, D.C.9
-
65
-
-
15444346942
-
Interactions of mast cell tryptase with thrombin receptors and PAR-2
-
Molino M., Barnathan E.S., Numerof R., Clark J., Dreyer M., Cumashi A., Hoxie J.A., Schecter N., Woolkalis M., Brass L.F. Interactions of mast cell tryptase with thrombin receptors and PAR-2. J Biol Chem 1997, 272:4043-4049.
-
(1997)
J Biol Chem
, vol.272
, pp. 4043-4049
-
-
Molino, M.1
Barnathan, E.S.2
Numerof, R.3
Clark, J.4
Dreyer, M.5
Cumashi, A.6
Hoxie, J.A.7
Schecter, N.8
Woolkalis, M.9
Brass, L.F.10
-
66
-
-
0027933068
-
Molecular cloning of a potential proteinase activated receptor
-
Nystedt S., Emilsson K., Wahlestedt C., Sundelin J. Molecular cloning of a potential proteinase activated receptor. Proc Natl Acad Sci USA 1994, 91:9208-9212.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9208-9212
-
-
Nystedt, S.1
Emilsson, K.2
Wahlestedt, C.3
Sundelin, J.4
-
67
-
-
0034624973
-
Tissue factor-and factor X-dependent activation of PAR2 by factor VIIa
-
Camerer E., Huang W., Coughlin S.R. Tissue factor-and factor X-dependent activation of PAR2 by factor VIIa. Proc Natl Acad Sci USA 2000, 97:5255-5260.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5255-5260
-
-
Camerer, E.1
Huang, W.2
Coughlin, S.R.3
-
68
-
-
0026690665
-
Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation
-
Hung D.T., Vu T.-K., Wheaton V.I., Ishii K., Coughlin S.R. Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation. J Clin Invest 1992, 89:1350-1353.
-
(1992)
J Clin Invest
, vol.89
, pp. 1350-1353
-
-
Hung, D.T.1
Vu, T.-K.2
Wheaton, V.I.3
Ishii, K.4
Coughlin, S.R.5
-
69
-
-
0026051572
-
A 14 amino acid peptide derived from the amino terminus of the cleaved thrombin receptor elevates intracellular calcium and stimulates prostacyclin production in human endothelial cells
-
Ngaiza J., Jaffe E. A 14 amino acid peptide derived from the amino terminus of the cleaved thrombin receptor elevates intracellular calcium and stimulates prostacyclin production in human endothelial cells. Biochem Biophys Res Commun 1991, 179:1656-1661.
-
(1991)
Biochem Biophys Res Commun
, vol.179
, pp. 1656-1661
-
-
Ngaiza, J.1
Jaffe, E.2
-
70
-
-
0026631543
-
Structure and function of the human platelet thrombin receptor. Studies using monoclonal antibodies directed against a defi ned domain within the receptor N terminus
-
Brass L., Vassallo R., Belmonte E., Ahuja M., Cichowski K., Hoxie J. Structure and function of the human platelet thrombin receptor. Studies using monoclonal antibodies directed against a defi ned domain within the receptor N terminus. J Biol Chem 1992, 267:13795-13798.
-
(1992)
J Biol Chem
, vol.267
, pp. 13795-13798
-
-
Brass, L.1
Vassallo, R.2
Belmonte, E.3
Ahuja, M.4
Cichowski, K.5
Hoxie, J.6
-
71
-
-
0029026320
-
Determinants of thrombin receptor cleavage receptor domains involved, specificity, and role of the
-
Ishii K., Gertstzen R.E., Zheng Y.W., Welsh J., Turck C.W., Coughlin S.R. Determinants of thrombin receptor cleavage receptor domains involved, specificity, and role of the. J Biol Chem 1995, 270:16435-16440.
-
(1995)
J Biol Chem
, vol.270
, pp. 16435-16440
-
-
Ishii, K.1
Gertstzen, R.E.2
Zheng, Y.W.3
Welsh, J.4
Turck, C.W.5
Coughlin, S.R.6
-
72
-
-
0026072517
-
Domains specifying thrombin-receptor interaction
-
Vu T., Wheaton V., Hung D., Charo I., Coughlin S. Domains specifying thrombin-receptor interaction. Nature (Lond) 1991, 353:674-677.
-
(1991)
Nature (Lond)
, vol.353
, pp. 674-677
-
-
Vu, T.1
Wheaton, V.2
Hung, D.3
Charo, I.4
Coughlin, S.5
-
73
-
-
0026003287
-
The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity
-
Liu L.-W., Vu T.-K., Esmon C., Coughlin S. The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity. J Biol Chem 1991, 266:16977-16980.
-
(1991)
J Biol Chem
, vol.266
, pp. 16977-16980
-
-
Liu, L.-W.1
Vu, T.-K.2
Esmon, C.3
Coughlin, S.4
-
74
-
-
0023096623
-
The regulation of natural anticoagulant pathways
-
Esmon C.T. The regulation of natural anticoagulant pathways. Science 1987, 235:1348-1352.
-
(1987)
Science
, vol.235
, pp. 1348-1352
-
-
Esmon, C.T.1
-
75
-
-
0025291082
-
Recombinant human protein C derivatives: Altered response to calcium resulting in enhanced activation by thrombin
-
Ehrlich H., Grinnell B.W., Jaskunas S., Esmon C.T., Yan S., Bang N. Recombinant human protein C derivatives: Altered response to calcium resulting in enhanced activation by thrombin. EMBO J 1990, 9:2367-2373.
-
(1990)
EMBO J
, vol.9
, pp. 2367-2373
-
-
Ehrlich, H.1
Grinnell, B.W.2
Jaskunas, S.3
Esmon, C.T.4
Yan, S.5
Bang, N.6
-
76
-
-
0025923430
-
Glu-192-Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin
-
LeBonniec B., Esmon C.T. Glu-192-Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin. Proc Natl Acad Sci USA 1991, 88:7371-7375.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7371-7375
-
-
LeBonniec, B.1
Esmon, C.T.2
-
77
-
-
0028209977
-
Crystallographic structures of thrombin complexed with thrombin receptor peptides: Existence of expected and novel binding modes
-
Mathews I.I., Padmanabhan K.P., Ganesh V., Tulinsky A., Ishii M., Chen J., Turck C.W., Coughlin S.R., Fenton J.W. Crystallographic structures of thrombin complexed with thrombin receptor peptides: Existence of expected and novel binding modes. Biochemistry 1994, 33:3266-3279.
-
(1994)
Biochemistry
, vol.33
, pp. 3266-3279
-
-
Mathews, I.I.1
Padmanabhan, K.P.2
Ganesh, V.3
Tulinsky, A.4
Ishii, M.5
Chen, J.6
Turck, C.W.7
Coughlin, S.R.8
Fenton, J.W.9
-
78
-
-
0028283850
-
Specificity of the thrombin receptor for agonist peptide is defi ned by its extracellular surface
-
Gertstzen R.E., Chen J.I., Ishii M., Ishii K., Wang L., Nanevicz T., Turck C.W., Vu T.-K., Coughlin S.R. Specificity of the thrombin receptor for agonist peptide is defi ned by its extracellular surface. Nature 1994, 368:648.
-
(1994)
Nature
, vol.368
, pp. 648
-
-
Gertstzen, R.E.1
Chen, J.I.2
Ishii, M.3
Ishii, K.4
Wang, L.5
Nanevicz, T.6
Turck, C.W.7
Vu, T.-K.8
Coughlin, S.R.9
-
79
-
-
0027155450
-
The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation
-
Bahou W., Coller B., Potter C., Norton K., Kutok J., Goligorsky M. The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation. J Clin Invest 1993, 91:1405-1413.
-
(1993)
J Clin Invest
, vol.91
, pp. 1405-1413
-
-
Bahou, W.1
Coller, B.2
Potter, C.3
Norton, K.4
Kutok, J.5
Goligorsky, M.6
-
80
-
-
0030066317
-
Thrombin receptor activating mutations. Alteration of an extracellular agonist recognition domain causes constitutive signaling
-
Nanevicz T., Wang L., Chen M., Ishii M., Coughlin S.R. Thrombin receptor activating mutations. Alteration of an extracellular agonist recognition domain causes constitutive signaling. J Biol Chem 1996, 271:702-706.
-
(1996)
J Biol Chem
, vol.271
, pp. 702-706
-
-
Nanevicz, T.1
Wang, L.2
Chen, M.3
Ishii, M.4
Coughlin, S.R.5
-
81
-
-
0034608013
-
Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 thrombin-cleaved PAR1
-
O'Brien P.J., et al. Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 thrombin-cleaved PAR1. J Biol Chem 2000, 275:13502-13509.
-
(2000)
J Biol Chem
, vol.275
, pp. 13502-13509
-
-
O'Brien, P.J.1
-
82
-
-
0027155450
-
The thrombin receptor extracellular domain contains sites crucial for peptide ligandinduced activation
-
Bahou W.F., Coller B.S., Potter C.L., Norton K.J., Kutok J.L., Goligorsky M.S. The thrombin receptor extracellular domain contains sites crucial for peptide ligandinduced activation. J Clin Invest 1993, 91:1405-1413.
-
(1993)
J Clin Invest
, vol.91
, pp. 1405-1413
-
-
Bahou, W.F.1
Coller, B.S.2
Potter, C.L.3
Norton, K.J.4
Kutok, J.L.5
Goligorsky, M.S.6
-
83
-
-
0026629249
-
Tethered ligand agonist peptides: Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function
-
Scarborough R., Naughton M., Teng W., Hung D., Rose J., Vu T., Wheaton V., Turck C., Coughlin S. Tethered ligand agonist peptides: Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function. J Biol Chem 1992, 267:13146-14149.
-
(1992)
J Biol Chem
, vol.267
, pp. 13146-14149
-
-
Scarborough, R.1
Naughton, M.2
Teng, W.3
Hung, D.4
Rose, J.5
Vu, T.6
Wheaton, V.7
Turck, C.8
Coughlin, S.9
-
84
-
-
0027488033
-
Immunologic analysis of the cloned platelet thrombin receptor activation mechanism: Evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment
-
Norton K.J., Scarborough R.M., Kutok J.L., Escobedo M.A., Nannizzi L., Coller B.S. Immunologic analysis of the cloned platelet thrombin receptor activation mechanism: Evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment. Blood 1993, 82:2125-2136.
-
(1993)
Blood
, vol.82
, pp. 2125-2136
-
-
Norton, K.J.1
Scarborough, R.M.2
Kutok, J.L.3
Escobedo, M.A.4
Nannizzi, L.5
Coller, B.S.6
-
85
-
-
0027527732
-
Substituting isoserine for serine in the thrombin receptor activation peptide SFLLRN confers resistance to aminopeptidase Minduced cleavage and inactivation
-
Coller B.S., Springer K.T., Scudder L.E., Kutok J.L., Ceruso M., Prestwich G.D. Substituting isoserine for serine in the thrombin receptor activation peptide SFLLRN confers resistance to aminopeptidase Minduced cleavage and inactivation. J Biol Chem 1993, 268:20741-20743.
-
(1993)
J Biol Chem
, vol.268
, pp. 20741-20743
-
-
Coller, B.S.1
Springer, K.T.2
Scudder, L.E.3
Kutok, J.L.4
Ceruso, M.5
Prestwich, G.D.6
-
86
-
-
0026775223
-
Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides
-
Vassallo J., Kieber-Emmons T., Cichowski K., Brass L.F. Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J Biol Chem 1992, 267:6081-6085.
-
(1992)
J Biol Chem
, vol.267
, pp. 6081-6085
-
-
Vassallo, J.1
Kieber-Emmons, T.2
Cichowski, K.3
Brass, L.F.4
-
87
-
-
0030868767
-
Release of the thrombin receptor (PAR-1) N-terminus from the surface of human platelets activated by thrombin
-
Ramachandran B., Klufas A., Molino M., Ahuja M., Hoxie J.A., Brass L.F. Release of the thrombin receptor (PAR-1) N-terminus from the surface of human platelets activated by thrombin. Thromb Haemost 1997, 78:1119-1124.
-
(1997)
Thromb Haemost
, vol.78
, pp. 1119-1124
-
-
Ramachandran, B.1
Klufas, A.2
Molino, M.3
Ahuja, M.4
Hoxie, J.A.5
Brass, L.F.6
-
88
-
-
0032539850
-
The cleaved peptide of the thrombin receptor is a strong platelet agonist
-
Furman M.I., Lu L., Benoit S.E., Becker R.C., Barnard M.R., Michelson A.D. The cleaved peptide of the thrombin receptor is a strong platelet agonist. Proc Natl Acad Sci USA 1998, 95:3082-3087.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3082-3087
-
-
Furman, M.I.1
Lu, L.2
Benoit, S.E.3
Becker, R.C.4
Barnard, M.R.5
Michelson, A.D.6
-
89
-
-
0028059276
-
Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes
-
Suidan H.S., Bouvier J., Schaerer E., Stone S.R., Monard D., Tschopp J. Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes. Proc Natl Acad Sci USA 1994, 91:8112-8116.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8112-8116
-
-
Suidan, H.S.1
Bouvier, J.2
Schaerer, E.3
Stone, S.R.4
Monard, D.5
Tschopp, J.6
-
90
-
-
0034090334
-
Meizothrombin, an intermediate of prothrombin activation stimulates human glioblastoma cells by interaction with PAR-1 type thrombin receptors
-
Kaufmann R., Zieger M., Tausch S., Henklein P., Nowak G. Meizothrombin, an intermediate of prothrombin activation stimulates human glioblastoma cells by interaction with PAR-1 type thrombin receptors. J Neurosci Res 2000, 59:643-648.
-
(2000)
J Neurosci Res
, vol.59
, pp. 643-648
-
-
Kaufmann, R.1
Zieger, M.2
Tausch, S.3
Henklein, P.4
Nowak, G.5
-
91
-
-
0026026907
-
Receptor and G protein-mediated responses to thrombin in HEL cells
-
Brass L.F., Manning D.R., Williams A.G., Woolkalis M.J., Poncz M. Receptor and G protein-mediated responses to thrombin in HEL cells. J Biol Chem 1991, 266:958-965.
-
(1991)
J Biol Chem
, vol.266
, pp. 958-965
-
-
Brass, L.F.1
Manning, D.R.2
Williams, A.G.3
Woolkalis, M.J.4
Poncz, M.5
-
92
-
-
0030947907
-
Endothelial cell thrombin receptors and PAR-2: Two protease-activated receptors located in a single cellular environment
-
Molino M., Woolkalis M.J., Reavey-Cantwell J., Practico D., Andrade-Gordon P., Brass L. Endothelial cell thrombin receptors and PAR-2: Two protease-activated receptors located in a single cellular environment. J Biol Chem 1997, 272:11133-11141.
-
(1997)
J Biol Chem
, vol.272
, pp. 11133-11141
-
-
Molino, M.1
Woolkalis, M.J.2
Reavey-Cantwell, J.3
Practico, D.4
Andrade-Gordon, P.5
Brass, L.6
-
93
-
-
0035874536
-
Gene induction by coagulation factor Xa is mediated by activation of proteaseactivated receptor 1
-
Riewald M., Kravchenko V., Petrovan R., O'Brien P., Brass L., Ulevitch R., Ruf W. Gene induction by coagulation factor Xa is mediated by activation of proteaseactivated receptor 1. Blood 2001, 97:3109-3116.
-
(2001)
Blood
, vol.97
, pp. 3109-3116
-
-
Riewald, M.1
Kravchenko, V.2
Petrovan, R.3
O'Brien, P.4
Brass, L.5
Ulevitch, R.6
Ruf, W.7
-
94
-
-
0029018204
-
Proteolysis of the human platelet and endothelial cell throm-bin receptor by neutrophil-derived cathepsin
-
Molino M., Blanchard N., Belmonte E., Tarver A.P., Abrams C., Hoxie J.A., Cerletti C., Brass L.F. Proteolysis of the human platelet and endothelial cell throm-bin receptor by neutrophil-derived cathepsin. J Biol Chem 1995, 270:11168-11175.
-
(1995)
J Biol Chem
, vol.270
, pp. 11168-11175
-
-
Molino, M.1
Blanchard, N.2
Belmonte, E.3
Tarver, A.P.4
Abrams, C.5
Hoxie, J.A.6
Cerletti, C.7
Brass, L.F.8
-
95
-
-
0029779961
-
Plasmin-platelet interaction involves cleavage of functional thrombin receptor
-
Kimura M., Andersen T.T., Fenton J.W., Bahou W.F., Aviv A. Plasmin-platelet interaction involves cleavage of functional thrombin receptor. Am J Physiol 1996, 271:C54-C60.
-
(1996)
Am J Physiol
, vol.271
-
-
Kimura, M.1
Andersen, T.T.2
Fenton, J.W.3
Bahou, W.F.4
Aviv, A.5
-
96
-
-
0030968521
-
Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: Evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor
-
Renesto P., Si-Tahar M., Moniatte M., Balloy V., Van Dorsselaer A., Pidard D., Chignard M. Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: Evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor. Blood 1997, 89:1944-1953.
-
(1997)
Blood
, vol.89
, pp. 1944-1953
-
-
Renesto, P.1
Si-Tahar, M.2
Moniatte, M.3
Balloy, V.4
Van Dorsselaer, A.5
Pidard, D.6
Chignard, M.7
-
97
-
-
0032510949
-
The human proteinase-activated receptor-3 (PAR-3) gene. Identifi cation within a PAR gene cluster and characterization in vascular endothelial cells and platelets
-
Schmidt V.A., Nierman W.C., Maglott D.R., Cupit L.D., Moskowitz K.A., Wainer J.A., Bahou W.F. The human proteinase-activated receptor-3 (PAR-3) gene. Identifi cation within a PAR gene cluster and characterization in vascular endothelial cells and platelets. J Biol Chem 1998, 273:15061-15068.
-
(1998)
J Biol Chem
, vol.273
, pp. 15061-15068
-
-
Schmidt, V.A.1
Nierman, W.C.2
Maglott, D.R.3
Cupit, L.D.4
Moskowitz, K.A.5
Wainer, J.A.6
Bahou, W.F.7
-
98
-
-
0033001930
-
Proteolytically activated receptor-3. A member of an emerging gene family of protease receptors expressed on vascular endothelial cells and platelets
-
Cupit L.D., Schmidt V.A., Bahou W.F. Proteolytically activated receptor-3. A member of an emerging gene family of protease receptors expressed on vascular endothelial cells and platelets. Trends Cardiovasc Med 1999, 9:42-48.
-
(1999)
Trends Cardiovasc Med
, vol.9
, pp. 42-48
-
-
Cupit, L.D.1
Schmidt, V.A.2
Bahou, W.F.3
-
99
-
-
0037783288
-
Extracellular mediators in atherosclerosis and thrombosis: Lessons from thrombin receptor knockout mice
-
Major C.D., Santulli R.J., Derian C.K., Andrade-Gordon P. Extracellular mediators in atherosclerosis and thrombosis: Lessons from thrombin receptor knockout mice. Arterioscler Thromb Vasc Biol 2003, 23:931-939.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 931-939
-
-
Major, C.D.1
Santulli, R.J.2
Derian, C.K.3
Andrade-Gordon, P.4
-
100
-
-
0032514474
-
A dual thrombin receptor system for platelet activation
-
Kahn M.L., Zheng Y.W., Huang W., Bigornia V., Zeng D., Moff S., Farese J., Tam C., Coughlin S.R. A dual thrombin receptor system for platelet activation. Nature 1998, 394:690-694.
-
(1998)
Nature
, vol.394
, pp. 690-694
-
-
Kahn, M.L.1
Zheng, Y.W.2
Huang, W.3
Bigornia, V.4
Zeng, D.5
Moff, S.6
Farese, J.7
Tam, C.8
Coughlin, S.R.9
-
101
-
-
0034629468
-
Cathepsin G activates protease-activated receptor-4 in human platelets
-
Sambrano G.R., et al. Cathepsin G activates protease-activated receptor-4 in human platelets. J Biol Chem 2000, 275:6819-6823.
-
(2000)
J Biol Chem
, vol.275
, pp. 6819-6823
-
-
Sambrano, G.R.1
-
102
-
-
0034733558
-
Structure-function analysis of proteaseactivated receptor 4 tethered ligand peptides. Determinants of specificity and utility in assays of receptor function
-
Faruqi T., Weiss E., Shapiro M.J., Huang W., Coughlin S.R. Structure-function analysis of proteaseactivated receptor 4 tethered ligand peptides. Determinants of specificity and utility in assays of receptor function. J Biol Chem 2000, 19728-19734.
-
(2000)
J Biol Chem
, pp. 19728-19734
-
-
Faruqi, T.1
Weiss, E.2
Shapiro, M.J.3
Huang, W.4
Coughlin, S.R.5
-
103
-
-
0029113121
-
Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
-
Nystedt S., Emilsson K., Larsson A.K., Strombeck B., Sundelin J. Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur J Biochem 1995, 232:84-89.
-
(1995)
Eur J Biochem
, vol.232
, pp. 84-89
-
-
Nystedt, S.1
Emilsson, K.2
Larsson, A.K.3
Strombeck, B.4
Sundelin, J.5
-
104
-
-
0030783689
-
Mitogenic responses mediated through the proteinase activated receptor-2 are induced by mast cell á-and α-tryptases
-
Mirza H., Schmidt V., Derian C., Jesty J., Bahou W. Mitogenic responses mediated through the proteinase activated receptor-2 are induced by mast cell á-and α-tryptases. Blood 1997, 90:3914-3922.
-
(1997)
Blood
, vol.90
, pp. 3914-3922
-
-
Mirza, H.1
Schmidt, V.2
Derian, C.3
Jesty, J.4
Bahou, W.5
-
105
-
-
0031806683
-
Differential expression of functional protease-activated receptor-2 (PAR-2) in human vascular smooth muscle cells
-
Molino M., Raghunath P., KuO A., Ahuja M., Hoxie J., Brass L., Barnathan E. Differential expression of functional protease-activated receptor-2 (PAR-2) in human vascular smooth muscle cells. Arterioscl, Thromb Vasc Biol 1998, 18:825-832.
-
(1998)
Arterioscl, Thromb Vasc Biol
, vol.18
, pp. 825-832
-
-
Molino, M.1
Raghunath, P.2
KuO, A.3
Ahuja, M.4
Hoxie, J.5
Brass, L.6
Barnathan, E.7
-
106
-
-
0030003829
-
The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. Molecular characterization and evidence for functional coupling to the thrombin receptor
-
Mirza H., Yatsula V., Bahou W.F. The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. Molecular characterization and evidence for functional coupling to the thrombin receptor. J Clin Invest 1996, 97:1705-1714.
-
(1996)
J Clin Invest
, vol.97
, pp. 1705-1714
-
-
Mirza, H.1
Yatsula, V.2
Bahou, W.F.3
-
107
-
-
0033926445
-
Expression of protease-activated receptor-2 during development
-
Jenkins A.L., Chinni C., DeNiesse M., Blackhart B.D. Expression of protease-activated receptor-2 during development. Dev Dyn 2000, 218:465-471.
-
(2000)
Dev Dyn
, vol.218
, pp. 465-471
-
-
Jenkins, A.L.1
Chinni, C.2
DeNiesse, M.3
Blackhart, B.D.4
-
108
-
-
0033971235
-
Agonists of proteinase-activated receptor 2 induce infl ammation by a neurogenic mechanism
-
Steinhoff M., Vergnolle N., Young S., Tognetto M., Amadesi S., Ennes H., Trevisani M., Hollenberg M., Wallace J., Caughey G.H., Mitchell S., Williams L., Geppetti P., Mayer E., Bunnett N. Agonists of proteinase-activated receptor 2 induce infl ammation by a neurogenic mechanism. Nat Med 2000, 6:151-158.
-
(2000)
Nat Med
, vol.6
, pp. 151-158
-
-
Steinhoff, M.1
Vergnolle, N.2
Young, S.3
Tognetto, M.4
Amadesi, S.5
Ennes, H.6
Trevisani, M.7
Hollenberg, M.8
Wallace, J.9
Caughey, G.H.10
Mitchell, S.11
Williams, L.12
Geppetti, P.13
Mayer, E.14
Bunnett, N.15
-
109
-
-
0032792955
-
Characterization of the infl ammatory response to proteinase-activated receptor-2 (PAR-2) -activating peptides in the rat paw
-
Vergnolle N., Hollenberg M.D., Sharkey K., Wallace J. Characterization of the infl ammatory response to proteinase-activated receptor-2 (PAR-2) -activating peptides in the rat paw. Br J Pharm 1999, 127:1053-1090.
-
(1999)
Br J Pharm
, vol.127
, pp. 1053-1090
-
-
Vergnolle, N.1
Hollenberg, M.D.2
Sharkey, K.3
Wallace, J.4
-
110
-
-
0033545627
-
A protective role for protease-activated receptors in the airways
-
Cocks T., Fong B., Chow J., Anderson G., Frauman A., Goldie R., Henry P., Carr M., Hamilton R., Moffatt J. A protective role for protease-activated receptors in the airways. Nature 1999, 398:156-160.
-
(1999)
Nature
, vol.398
, pp. 156-160
-
-
Cocks, T.1
Fong, B.2
Chow, J.3
Anderson, G.4
Frauman, A.5
Goldie, R.6
Henry, P.7
Carr, M.8
Hamilton, R.9
Moffatt, J.10
-
111
-
-
0032929826
-
Increased expression of protease activated receptor-2 (PAR-2) in balloon-injured rat carotid artery
-
Damiano B.P., D'Andrea M.R., de Gavavilla L., Cheung W.M., Andrade-Gordon P. Increased expression of protease activated receptor-2 (PAR-2) in balloon-injured rat carotid artery. Thromb Haemost 1999, 81:808-814.
-
(1999)
Thromb Haemost
, vol.81
, pp. 808-814
-
-
Damiano, B.P.1
D'Andrea, M.R.2
de Gavavilla, L.3
Cheung, W.M.4
Andrade-Gordon, P.5
-
112
-
-
0032867472
-
Evidence for selective effects of chronic hypertension on cerebral artery vasodilation to protease-activated receptor-2 activation
-
Sobey C., Moffatt J., Cocks T. Evidence for selective effects of chronic hypertension on cerebral artery vasodilation to protease-activated receptor-2 activation. Stroke 1999, 30:1933-1940.
-
(1999)
Stroke
, vol.30
, pp. 1933-1940
-
-
Sobey, C.1
Moffatt, J.2
Cocks, T.3
-
113
-
-
3042697246
-
Thrombin's faces revealed: Cellular effects include induction of neoangiogenesis
-
Bahou W.F. Thrombin's faces revealed: Cellular effects include induction of neoangiogenesis. J Thromb Haemost 2003, 1:2078-2080.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 2078-2080
-
-
Bahou, W.F.1
-
114
-
-
0022311436
-
Thrombin-elicited contractile responses of aortic smooth muscle
-
Walz D.A., Anderson G.F., Ciaglowski R.E., Aiken M., Fenton J.W. Thrombin-elicited contractile responses of aortic smooth muscle. Proc Soc Exp Biol Med 1985, 180:518-526.
-
(1985)
Proc Soc Exp Biol Med
, vol.180
, pp. 518-526
-
-
Walz, D.A.1
Anderson, G.F.2
Ciaglowski, R.E.3
Aiken, M.4
Fenton, J.W.5
-
115
-
-
0033529539
-
An integrated study of fibrinogen during blood coagulation
-
Brummel K., Butenas S., Mann K.G. An integrated study of fibrinogen during blood coagulation. J Biol Chem 1999, 274:22862-22870.
-
(1999)
J Biol Chem
, vol.274
, pp. 22862-22870
-
-
Brummel, K.1
Butenas, S.2
Mann, K.G.3
-
117
-
-
0025563384
-
Hirudin, heparin and placebo during deep arterial injury in the pig: The in vivo role of thrombin in platelet-mediated thrombosis
-
Heras M., Chesebro J., Webster M., Mruk J., Grill D., Penny W., Bowie E.J.W., Badimon L., Fuster V. Hirudin, heparin and placebo during deep arterial injury in the pig: The in vivo role of thrombin in platelet-mediated thrombosis. Circulation 1990, 82:1476-1484.
-
(1990)
Circulation
, vol.82
, pp. 1476-1484
-
-
Heras, M.1
Chesebro, J.2
Webster, M.3
Mruk, J.4
Grill, D.5
Penny, W.6
Bowie, E.J.W.7
Badimon, L.8
Fuster, V.9
-
118
-
-
0030999569
-
Interaction of a thrombin inhibitor and a platelet GP IIb/IIIa antagonist in vivo: Evidence that thrombin mediates platelet aggregation and subsequent thromboxane A2 formation during coronary thrombolysis
-
Practico D., Murphy N., Fitzgerald D. Interaction of a thrombin inhibitor and a platelet GP IIb/IIIa antagonist in vivo: Evidence that thrombin mediates platelet aggregation and subsequent thromboxane A2 formation during coronary thrombolysis. J Pharmacol Exp Ther 1997, 281:1178-1185.
-
(1997)
J Pharmacol Exp Ther
, vol.281
, pp. 1178-1185
-
-
Practico, D.1
Murphy, N.2
Fitzgerald, D.3
-
119
-
-
0037310962
-
Blockade of the thrombin receptor protease-activated receptor-1 with a smallmolecule antagonist prevents thrombus formation and vascular occlusion in nonhuman primates
-
Derian C.K., Damiano B.P., Addo M.F., Darrow A.L., D'Andrea M.R., Nedelman M., Zhang H.C., Maryanoff B.E., Andrade-Gordon P. Blockade of the thrombin receptor protease-activated receptor-1 with a smallmolecule antagonist prevents thrombus formation and vascular occlusion in nonhuman primates. J Pharmacol Exp Ther 2003, 304:855-861.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 855-861
-
-
Derian, C.K.1
Damiano, B.P.2
Addo, M.F.3
Darrow, A.L.4
D'Andrea, M.R.5
Nedelman, M.6
Zhang, H.C.7
Maryanoff, B.E.8
Andrade-Gordon, P.9
-
120
-
-
0029057398
-
An antibody against the exosite of the cloned thrombin receptor inhibits experimental arterial thrombosis in the African green monkey
-
Cook J., Sitko G., Bednar B., Condra C., Mellott M., Feng D., Nutt R., Shafer J., Gould R., Connolly T. An antibody against the exosite of the cloned thrombin receptor inhibits experimental arterial thrombosis in the African green monkey. Circulation 1995, 91:2961-2971.
-
(1995)
Circulation
, vol.91
, pp. 2961-2971
-
-
Cook, J.1
Sitko, G.2
Bednar, B.3
Condra, C.4
Mellott, M.5
Feng, D.6
Nutt, R.7
Shafer, J.8
Gould, R.9
Connolly, T.10
-
121
-
-
0033960184
-
Protective effect of a thrombin receptor (protease-activated receptor 1) gene polymorphism toward venous thromboembolism
-
Arnaud E., Nicaud V., Poirier O., Rendu F., Alhenc-Gelas M., Fiessinger J., Emmerich J., Aiach M. Protective effect of a thrombin receptor (protease-activated receptor 1) gene polymorphism toward venous thromboembolism. Arterioscl Thromb Vasc Biol 2000, 20:585-592.
-
(2000)
Arterioscl Thromb Vasc Biol
, vol.20
, pp. 585-592
-
-
Arnaud, E.1
Nicaud, V.2
Poirier, O.3
Rendu, F.4
Alhenc-Gelas, M.5
Fiessinger, J.6
Emmerich, J.7
Aiach, M.8
-
122
-
-
0026497368
-
Thrombin receptor expression in normal and atherosclerotic human arteries
-
Nelken N.A., Soifer S.J., O'Keefe J., Vu -K.H., Charo I.F., Coughlin S.R. Thrombin receptor expression in normal and atherosclerotic human arteries. J Clin Invest 1992, 90:1614-1621.
-
(1992)
J Clin Invest
, vol.90
, pp. 1614-1621
-
-
Nelken, N.A.1
Soifer, S.J.2
O'Keefe, J.3
Vu, -K.H.4
Charo, I.F.5
Coughlin, S.R.6
-
123
-
-
0028936787
-
Role of the thrombin receptor in restenosis and atherosclerosis
-
Baykal D., Schmedtje J., Runge M. Role of the thrombin receptor in restenosis and atherosclerosis. Am J Cardiol 1995, 75:82B-87B.
-
(1995)
Am J Cardiol
, vol.75
-
-
Baykal, D.1
Schmedtje, J.2
Runge, M.3
-
124
-
-
0027967395
-
Characterization of thrombin receptor expression during vascular lesion formation
-
Wilcox J., Rodriguez J., Subramanian R., Ollerenshaw J., Zhong C., Hayzer D., Horaist C., Hanson S., Lumdsen A., Salam T., et al. Characterization of thrombin receptor expression during vascular lesion formation. Circ Res 1994, 75:1029-1038.
-
(1994)
Circ Res
, vol.75
, pp. 1029-1038
-
-
Wilcox, J.1
Rodriguez, J.2
Subramanian, R.3
Ollerenshaw, J.4
Zhong, C.5
Hayzer, D.6
Horaist, C.7
Hanson, S.8
Lumdsen, A.9
Salam, T.10
-
125
-
-
0032538866
-
Differential regulation of protease activated receptor-1 and tissue plasminogen activator expression by shear stress in vascular smooth muscle cells
-
Papadaki M., Ruef J., Nguyen K., Li F., Patterson C., Eskin S., McIntire L., Runge M. Differential regulation of protease activated receptor-1 and tissue plasminogen activator expression by shear stress in vascular smooth muscle cells. Circ Res 1998, 83:1027-1034.
-
(1998)
Circ Res
, vol.83
, pp. 1027-1034
-
-
Papadaki, M.1
Ruef, J.2
Nguyen, K.3
Li, F.4
Patterson, C.5
Eskin, S.6
McIntire, L.7
Runge, M.8
-
126
-
-
0028946244
-
Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences
-
Chaikoff E.L., Caban R., Yan C., Rao G., Runge M. Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences. J Biol Chem 1995, 270:7431-7436.
-
(1995)
J Biol Chem
, vol.270
, pp. 7431-7436
-
-
Chaikoff, E.L.1
Caban, R.2
Yan, C.3
Rao, G.4
Runge, M.5
-
127
-
-
0031053192
-
Intimal hyperplasia following vascular injury is not inhibited by an antisense thrombin receptor oligodeoxynucleotide
-
Herbert J., Guy A., Lamarche I., Mares A., Savi P., Dol F. Intimal hyperplasia following vascular injury is not inhibited by an antisense thrombin receptor oligodeoxynucleotide. J Cell Physiol 1997, 170:106-114.
-
(1997)
J Cell Physiol
, vol.170
, pp. 106-114
-
-
Herbert, J.1
Guy, A.2
Lamarche, I.3
Mares, A.4
Savi, P.5
Dol, F.6
-
128
-
-
0032543264
-
Antibody to thrombin receptor inhibits neointimal smooth muscle cell accumulation without causing inhibition of platelet aggregation or altering hemostatic parameters after angioplasty in rat
-
Takada M., Tanaka H., Yamada T., Ito O., Kogushi M., Yanagimachi M., Kawamura T., Musha T., Yoshida F., Ito M., Kobayashi H., Yoshitake S., Saito I. Antibody to thrombin receptor inhibits neointimal smooth muscle cell accumulation without causing inhibition of platelet aggregation or altering hemostatic parameters after angioplasty in rat. Circ Res 1998, 82:980-987.
-
(1998)
Circ Res
, vol.82
, pp. 980-987
-
-
Takada, M.1
Tanaka, H.2
Yamada, T.3
Ito, O.4
Kogushi, M.5
Yanagimachi, M.6
Kawamura, T.7
Musha, T.8
Yoshida, F.9
Ito, M.10
Kobayashi, H.11
Yoshitake, S.12
Saito, I.13
-
129
-
-
0033396454
-
Altered vascular injury responses in mice defi cient in protease-activated receptor-1
-
Cheung W.M., D'Andrea M.R., Andrade-Gordon P., Damiano B.P. Altered vascular injury responses in mice defi cient in protease-activated receptor-1. Arterioscler Thromb Vasc Biol 1999, 19:3014-3024.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 3014-3024
-
-
Cheung, W.M.1
D'Andrea, M.R.2
Andrade-Gordon, P.3
Damiano, B.P.4
-
130
-
-
0034651718
-
Introduction: Are natural anticoagulants candidates for modulating the infl ammatory response to endotoxin?
-
Esmon C.T. Introduction: Are natural anticoagulants candidates for modulating the infl ammatory response to endotoxin?. Blood 2000, 95:1113-1116.
-
(2000)
Blood
, vol.95
, pp. 1113-1116
-
-
Esmon, C.T.1
-
131
-
-
0023684353
-
Regulation of thrombin generation and functions
-
Fenton J. Regulation of thrombin generation and functions. Semin Thromb Hemost 1988, 14:234-240.
-
(1988)
Semin Thromb Hemost
, vol.14
, pp. 234-240
-
-
Fenton, J.1
-
132
-
-
0022924087
-
Thrombin-cellular interactions
-
Shuman M. Thrombin-cellular interactions. Ann NY Acad Sci 1986, 485:229-238.
-
(1986)
Ann NY Acad Sci
, vol.485
, pp. 229-238
-
-
Shuman, M.1
-
133
-
-
0032525041
-
Potential mechanisms for a proinfl ammatory vascular cytokine response to coagulation activation
-
Johnson K., Choi Y., DeGroot E., Samuels I., Creasey A., Aarden L. Potential mechanisms for a proinfl ammatory vascular cytokine response to coagulation activation. J Immunol 1998, 160:5130-5135.
-
(1998)
J Immunol
, vol.160
, pp. 5130-5135
-
-
Johnson, K.1
Choi, Y.2
DeGroot, E.3
Samuels, I.4
Creasey, A.5
Aarden, L.6
-
134
-
-
0029862685
-
Thrombin functions as an infl ammatory mediator through activation of its receptor
-
Cirino G., et al. Thrombin functions as an infl ammatory mediator through activation of its receptor. J Exp Med 1996, 183:821-827.
-
(1996)
J Exp Med
, vol.183
, pp. 821-827
-
-
Cirino, G.1
-
135
-
-
0027511564
-
T cell proliferative responses and cytokine production
-
Naldini A., Carney D.H., Bocci V., Klimpel K., Assuncion M., Soares L., Kimpel G. T cell proliferative responses and cytokine production. Cell Immunol 1993, 147:367-377.
-
(1993)
Cell Immunol
, vol.147
, pp. 367-377
-
-
Naldini, A.1
Carney, D.H.2
Bocci, V.3
Klimpel, K.4
Assuncion, M.5
Soares, L.6
Kimpel, G.7
-
136
-
-
0020570701
-
Monocyte chemotaxis: Stimulation by specific exosite region in thrombin
-
Bar-Shavit R., Kahn A., Wilner G.D., et al. Monocyte chemotaxis: Stimulation by specific exosite region in thrombin. Science 1983, 220:728-731.
-
(1983)
Science
, vol.220
, pp. 728-731
-
-
Bar-Shavit, R.1
Kahn, A.2
Wilner, G.D.3
-
137
-
-
0020662680
-
Chemotactic response of monocytes to thrombin
-
Bar-Shavit R., Kahn A., Fenton J.W., Wilner G.D. Chemotactic response of monocytes to thrombin. J Cell Biol 1983, 96:282-285.
-
(1983)
J Cell Biol
, vol.96
, pp. 282-285
-
-
Bar-Shavit, R.1
Kahn, A.2
Fenton, J.W.3
Wilner, G.D.4
-
138
-
-
0025729812
-
Mitogenic effects of coagulation factor XII and factor XIIa on Hep G2 cells
-
Schmeidler-Sapiro K.T., Ratnoff O.D., Gordon E.M. Mitogenic effects of coagulation factor XII and factor XIIa on Hep G2 cells. Proc Natl Acad Sci USA 1991, 88:4382-4385.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4382-4385
-
-
Schmeidler-Sapiro, K.T.1
Ratnoff, O.D.2
Gordon, E.M.3
-
139
-
-
0033571257
-
Tissue factor and factor VIIa receptor/ ligand interactions induce proinfl ammatory effects in macrophages
-
Cunningham M., Romas P., Hutchinson P., Holdsworth S., Tipping P. Tissue factor and factor VIIa receptor/ ligand interactions induce proinfl ammatory effects in macrophages. Blood 1999, 94:3413-3420.
-
(1999)
Blood
, vol.94
, pp. 3413-3420
-
-
Cunningham, M.1
Romas, P.2
Hutchinson, P.3
Holdsworth, S.4
Tipping, P.5
-
140
-
-
0028965560
-
2+ signals in J82 cells, transfected GDS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor
-
2+ signals in J82 cells, transfected GDS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor. J Biol Chem 1995, 270:4650-4660.
-
(1995)
J Biol Chem
, vol.270
, pp. 4650-4660
-
-
Rottingen, J.1
Enden, T.2
Camerer, E.3
Iversen, J.4
Prydz, H.5
-
141
-
-
0029847188
-
2+ oscillations in Madin-Darby canine kidney cells only when proteolytically active
-
2+ oscillations in Madin-Darby canine kidney cells only when proteolytically active. J Biol Chem 1996, 271:29042.
-
(1996)
J Biol Chem
, vol.271
, pp. 29042
-
-
Camerer, E.1
Rottingen, J.2
Iversen, J.3
Prydz, H.4
-
142
-
-
0029989386
-
Effector cell protease receptor-1 is a vascular receptor for coagulation factor Xa
-
Nicholson A.C., Nachman R.L., Altieri D.C., Summers B.D., Ruf W., Edgington T.S., Hajjar D.P. Effector cell protease receptor-1 is a vascular receptor for coagulation factor Xa. J Biol Chem 1996, 271:28407-28413.
-
(1996)
J Biol Chem
, vol.271
, pp. 28407-28413
-
-
Nicholson, A.C.1
Nachman, R.L.2
Altieri, D.C.3
Summers, B.D.4
Ruf, W.5
Edgington, T.S.6
Hajjar, D.P.7
-
143
-
-
15844401726
-
The proteinase-activated receptor 2 is induced by infl ammatory mediators in human endothelial cells
-
Nystedt S., Ramakrishnan S., Sundelin J. The proteinase-activated receptor 2 is induced by infl ammatory mediators in human endothelial cells. J Biol Chem 1996, 271:14910-14915.
-
(1996)
J Biol Chem
, vol.271
, pp. 14910-14915
-
-
Nystedt, S.1
Ramakrishnan, S.2
Sundelin, J.3
-
144
-
-
0034648757
-
Thrombin signalling and proteaseactivated receptors
-
Coughlin S.R. Thrombin signalling and proteaseactivated receptors. Nature 2000, 407:258-264.
-
(2000)
Nature
, vol.407
, pp. 258-264
-
-
Coughlin, S.R.1
-
145
-
-
0023122016
-
Protein C prevents the coagulopathic and lethal effects of E. coli infusion in the baboon
-
Taylor J., Chang A., Esmon C.T., D'Angelo A., Vigano-D'angelo S., Blick K. Protein C prevents the coagulopathic and lethal effects of E. coli infusion in the baboon. J Clin Invest 1987, 97:918-925.
-
(1987)
J Clin Invest
, vol.97
, pp. 918-925
-
-
Taylor, J.1
Chang, A.2
Esmon, C.T.3
D'Angelo, A.4
Vigano-D'angelo, S.5
Blick, K.6
-
146
-
-
0025904459
-
Lethal, E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody
-
1991
-
Taylor J., Chang A., Ruf W., Morrissey J., Hinshaw L., Catlett R., Blick K., Edginton T. Lethal, E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody. Circ Shock 1991, 33-127134. 1991.
-
(1991)
Circ Shock
, pp. 33-127134
-
-
Taylor, J.1
Chang, A.2
Ruf, W.3
Morrissey, J.4
Hinshaw, L.5
Catlett, R.6
Blick, K.7
Edginton, T.8
-
147
-
-
0034614895
-
Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal infl ammation in crescentic glomemlonephritis
-
Cunningham M., Rondeau E., Chen X., Coughlin S.R., Holdsworth S., Tipping P. Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal infl ammation in crescentic glomemlonephritis. J Exp Med 2000, 191:455-462.
-
(2000)
J Exp Med
, vol.191
, pp. 455-462
-
-
Cunningham, M.1
Rondeau, E.2
Chen, X.3
Coughlin, S.R.4
Holdsworth, S.5
Tipping, P.6
-
148
-
-
0032793201
-
Alpha-Thrombin stimulates contraction of human bronchial rings by activation of protease-activated receptors
-
Hauck R., Schulz C., Schomig A., Hoffman R., Panettieri J. alpha-Thrombin stimulates contraction of human bronchial rings by activation of protease-activated receptors. Am J Phys 1999, 277:L22-L29.
-
(1999)
Am J Phys
, vol.277
-
-
Hauck, R.1
Schulz, C.2
Schomig, A.3
Hoffman, R.4
Panettieri, J.5
-
149
-
-
0032061273
-
Protease-activated receptors and their role in IL-6 and NF-IL-6 expression in human gingival fi broblasts
-
Hou L., Ravenall S., Macey M., Harriott P., Kapas S., Howells G.L. Protease-activated receptors and their role in IL-6 and NF-IL-6 expression in human gingival fi broblasts. J Periodontal Res 1998, 33:205-211.
-
(1998)
J Periodontal Res
, vol.33
, pp. 205-211
-
-
Hou, L.1
Ravenall, S.2
Macey, M.3
Harriott, P.4
Kapas, S.5
Howells, G.L.6
-
150
-
-
0037247658
-
Essential role for proteinase-activated receptor-2 in arthritis
-
Ferrell W.R., Lockhart J.C., Kelso E.B., Dunning L., Plevin R., Meek S.E., Smith A.J., Hunter G.D., McLean J.S., McGarry F., Ramage R., Jiang L., Kanke T., Kawagoe J. Essential role for proteinase-activated receptor-2 in arthritis. J Clin Invest 2003, 111:35-41.
-
(2003)
J Clin Invest
, vol.111
, pp. 35-41
-
-
Ferrell, W.R.1
Lockhart, J.C.2
Kelso, E.B.3
Dunning, L.4
Plevin, R.5
Meek, S.E.6
Smith, A.J.7
Hunter, G.D.8
McLean, J.S.9
McGarry, F.10
Ramage, R.11
Jiang, L.12
Kanke, T.13
Kawagoe, J.14
-
151
-
-
0033639115
-
Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing infl ammation
-
Ehrlich J., Boyle E., Labriola J., Kovacich J., Santucci R., Fearns C., Morgan E., Yun W., Luther T., Kojikawa O., Martin T., Pohlman T., Vernier E., Mackman N. Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing infl ammation. Am J Pathol 2000, 157:1849-1862.
-
(2000)
Am J Pathol
, vol.157
, pp. 1849-1862
-
-
Ehrlich, J.1
Boyle, E.2
Labriola, J.3
Kovacich, J.4
Santucci, R.5
Fearns, C.6
Morgan, E.7
Yun, W.8
Luther, T.9
Kojikawa, O.10
Martin, T.11
Pohlman, T.12
Vernier, E.13
Mackman, N.14
-
152
-
-
0037163104
-
Proteaseactivated receptor-2 stimulates angiogenesis and accelerates hemodynamic recovery in a mouse model of hindlimb ischemia
-
Milia A.F., Salis M.B., Stacca T., Pinna A., Madeddu P., Trevisani M., Geppetti P., Emanueli C. Proteaseactivated receptor-2 stimulates angiogenesis and accelerates hemodynamic recovery in a mouse model of hindlimb ischemia. Circ Res 2002, 91:346-352.
-
(2002)
Circ Res
, vol.91
, pp. 346-352
-
-
Milia, A.F.1
Salis, M.B.2
Stacca, T.3
Pinna, A.4
Madeddu, P.5
Trevisani, M.6
Geppetti, P.7
Emanueli, C.8
-
153
-
-
0035923526
-
Proteinase-activated receptor 2 is an anti-infl ammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis
-
Fiorucci S., Mencarelli A., Palazzetti B., Distrutti E., Vergnolle N., Hollenberg M.D., Wallace J.L., Morelli A., Cirino G. Proteinase-activated receptor 2 is an anti-infl ammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis. Proc Natl Acad Sci USA 2001, 98:13936-13941.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13936-13941
-
-
Fiorucci, S.1
Mencarelli, A.2
Palazzetti, B.3
Distrutti, E.4
Vergnolle, N.5
Hollenberg, M.D.6
Wallace, J.L.7
Morelli, A.8
Cirino, G.9
-
154
-
-
0027258993
-
Chromosomal assignment of the human thrombin receptor gene: Localization to region q13 of chromosome 5
-
Bahou W.F., Nierman W.C., Durkin A.S., Potter C.L., Demetrick D.J. Chromosomal assignment of the human thrombin receptor gene: Localization to region q13 of chromosome 5. Blood 1993, 82:1532-1537.
-
(1993)
Blood
, vol.82
, pp. 1532-1537
-
-
Bahou, W.F.1
Nierman, W.C.2
Durkin, A.S.3
Potter, C.L.4
Demetrick, D.J.5
-
155
-
-
0029919173
-
Genomic cloning and characterization of the human thrombin receptor gene: Evidence for a novel gene family that includes PAR-2
-
Schmidt V., Vitale E., Bahou W. Genomic cloning and characterization of the human thrombin receptor gene: Evidence for a novel gene family that includes PAR-2. J Biol Chem 1996, 271:9307-9312.
-
(1996)
J Biol Chem
, vol.271
, pp. 9307-9312
-
-
Schmidt, V.1
Vitale, E.2
Bahou, W.3
-
156
-
-
0032483456
-
Gene and locus structure and chromosomal localization of the protease-activated receptor gene family
-
Kahn M.L., Hammes S.R., Botka C., Coughlin S.R. Gene and locus structure and chromosomal localization of the protease-activated receptor gene family. J Biol Chem 1998, 273:23290-23296.
-
(1998)
J Biol Chem
, vol.273
, pp. 23290-23296
-
-
Kahn, M.L.1
Hammes, S.R.2
Botka, C.3
Coughlin, S.R.4
-
157
-
-
0013588997
-
Protease-activated receptor genes are clustered on 5q13
-
Guyonett D., Boissear J., Arvelier B., Nurden A. Protease-activated receptor genes are clustered on 5q13. Blood 1998, 92:25.
-
(1998)
Blood
, vol.92
, pp. 25
-
-
Guyonett, D.1
Boissear, J.2
Arvelier, B.3
Nurden, A.4
-
158
-
-
0038620337
-
IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization
-
Schmidt V.A., Scudder L., Devoe C.E., Bernards A., Cupit L.D., Bahou W.F. IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization. Blood 2003, 101:3021-3028.
-
(2003)
Blood
, vol.101
, pp. 3021-3028
-
-
Schmidt, V.A.1
Scudder, L.2
Devoe, C.E.3
Bernards, A.4
Cupit, L.D.5
Bahou, W.F.6
-
159
-
-
0032486191
-
Shotgun sequencing of the human genome
-
Venter J., Adams M., Sutton G., Kerlavage A., Smith H., Hunkapiller M. Shotgun sequencing of the human genome. Science 1998, 280:1540-1542.
-
(1998)
Science
, vol.280
, pp. 1540-1542
-
-
Venter, J.1
Adams, M.2
Sutton, G.3
Kerlavage, A.4
Smith, H.5
Hunkapiller, M.6
-
160
-
-
0030946582
-
The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13
-
Schmidt V.A., Nierman W.C., Feldblyum T.V., Maglott D.R., Bahou W.F. The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13. Br J Haematol 1997, 97:523-529.
-
(1997)
Br J Haematol
, vol.97
, pp. 523-529
-
-
Schmidt, V.A.1
Nierman, W.C.2
Feldblyum, T.V.3
Maglott, D.R.4
Bahou, W.F.5
-
161
-
-
3943058758
-
Distinct PAR/IQGAP expression patterns during murine development: Implications for thrombin-associated cytoskeletal reorganization
-
Cupit L.D., Schmidt V.A., Miller F., Bahou W.F. Distinct PAR/IQGAP expression patterns during murine development: Implications for thrombin-associated cytoskeletal reorganization. Mamm Genome 2004, 15:618-629.
-
(2004)
Mamm Genome
, vol.15
, pp. 618-629
-
-
Cupit, L.D.1
Schmidt, V.A.2
Miller, F.3
Bahou, W.F.4
-
162
-
-
0025183708
-
Basic local alignment search tool
-
Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J Mol Biol 1990, 215:403-410.
-
(1990)
J Mol Biol
, vol.215
, pp. 403-410
-
-
Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
-
163
-
-
0030008312
-
Role of the thrombin receptor in development and evidence for a second receptor
-
Connolly A., Ishihara H., Kahn M.L., Farese R.V., Coughlin S.R. Role of the thrombin receptor in development and evidence for a second receptor. Nature 1996, 38:516-519.
-
(1996)
Nature
, vol.38
, pp. 516-519
-
-
Connolly, A.1
Ishihara, H.2
Kahn, M.L.3
Farese, R.V.4
Coughlin, S.R.5
-
164
-
-
8044253419
-
Biological consequences of thrombin receptor defi-ciency in mice
-
Darrow A.L., Fung-Leung W., Ye R.D., Santulli R.J., Cheung W.M., Derian C.K., Burns C.L., Damiano B.P., Zhou L., Keena C.M., Peterson P., Andrade-Gordon P. Biological consequences of thrombin receptor defi-ciency in mice. Thromb Haemost 1996, 76:860-866.
-
(1996)
Thromb Haemost
, vol.76
, pp. 860-866
-
-
Darrow, A.L.1
Fung-Leung, W.2
Ye, R.D.3
Santulli, R.J.4
Cheung, W.M.5
Derian, C.K.6
Burns, C.L.7
Damiano, B.P.8
Zhou, L.9
Keena, C.M.10
Peterson, P.11
Andrade-Gordon, P.12
-
165
-
-
0028040603
-
Species variability in platelet and other cellular respon siveness to thrombin receptor-derived peptides
-
Connolly T.M., Condra C., Feng D.-M., Cook J.J., Stranieri M.T., Reilly C.F., Nutt R.F., Gould R.J. Species variability in platelet and other cellular respon siveness to thrombin receptor-derived peptides. Thromb Haemost 1994, 72:627-633.
-
(1994)
Thromb Haemost
, vol.72
, pp. 627-633
-
-
Connolly, T.M.1
Condra, C.2
Feng, D.-M.3
Cook, J.J.4
Stranieri, M.T.5
Reilly, C.F.6
Nutt, R.F.7
Gould, R.J.8
-
166
-
-
0029016907
-
Species differences in platelet responses to thrombin and SFLLKN. Receptor-mediated calcium mobilization and aggregation and regulation by protein kinases
-
Derian C.K., Santulli R.J., Tomko K.A., Haertlein B., Andrade-Gordon P. Species differences in platelet responses to thrombin and SFLLKN. Receptor-mediated calcium mobilization and aggregation and regulation by protein kinases. Thromb Res 1995, 6:505-519.
-
(1995)
Thromb Res
, vol.6
, pp. 505-519
-
-
Derian, C.K.1
Santulli, R.J.2
Tomko, K.A.3
Haertlein, B.4
Andrade-Gordon, P.5
-
167
-
-
0027231364
-
Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets
-
Kinlough-Rathbone R.L., Rand M., Packham M.A. Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets. Blood 1993, 82:103-106.
-
(1993)
Blood
, vol.82
, pp. 103-106
-
-
Kinlough-Rathbone, R.L.1
Rand, M.2
Packham, M.A.3
-
168
-
-
0029854371
-
Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V
-
Cui J., O'Shea K.S., Purkayastha A., Saunders T.L., Ginsburg D. Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V. Nature (Lond) 1996, 384:66-68.
-
(1996)
Nature (Lond)
, vol.384
, pp. 66-68
-
-
Cui, J.1
O'Shea, K.S.2
Purkayastha, A.3
Saunders, T.L.4
Ginsburg, D.5
-
169
-
-
0032560553
-
Prothrombin defi ciency results in embryonic and neonatal lethality in mice
-
Sun W.Y., Witte D.P., Degen J.L., Colbert M.C., Burkart M.C., Holmbäck K., Xiao Q., Bugge H., Degen S.J. Prothrombin defi ciency results in embryonic and neonatal lethality in mice. Proc Natl Acad Sci USA 1998, 95:7597-7602.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7597-7602
-
-
Sun, W.Y.1
Witte, D.P.2
Degen, J.L.3
Colbert, M.C.4
Burkart, M.C.5
Holmbäck, K.6
Xiao, Q.7
Bugge, H.8
Degen, S.J.9
-
170
-
-
0032560579
-
Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin defi ciency in mice
-
Xue J., Wu Q., Westfi eld L.A., Tuley E.A., Lu D., Zhang Q., Shim K., Zheng X., Sadler J.E. Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin defi ciency in mice. Proc Natl Acad Sci USA 1998, 95:7603-7607.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7603-7607
-
-
Xue, J.1
Wu, Q.2
Westfi, E.L.A.3
Tuley, E.A.4
Lu, D.5
Zhang, Q.6
Shim, K.7
Zheng, X.8
Sadler, J.E.9
-
171
-
-
0029908545
-
Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation
-
Bugge H., Xiao Q., Kombrinck K., Flock M., Holmbäck K., Danton M., Colbert M.C., et al. Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation. Proc Natl Acad Sci USA 1996, 93:6258-6263.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6258-6263
-
-
Bugge, H.1
Xiao, Q.2
Kombrinck, K.3
Flock, M.4
Holmbäck, K.5
Danton, M.6
Colbert, M.C.7
-
172
-
-
9544227474
-
Role of tissue factor in embryonic blood vessel development
-
Carmeliet P., Mackman N., Moons Luther T., Gressens P., Van Vlaenderen I., Demunc K., Kasper M., Breier G., Evrard P., Muller M., Risau W., Edgington T., Coleen D. Role of tissue factor in embryonic blood vessel development. Nature 1996, 383:73-75.
-
(1996)
Nature
, vol.383
, pp. 73-75
-
-
Carmeliet, P.1
Mackman, N.2
Moons, L.T.3
Gressens, P.4
Van Vlaenderen, I.5
Demunc, K.6
Kasper, M.7
Breier, G.8
Evrard, P.9
Muller, M.10
Risau, W.11
Edgington, T.12
Coleen, D.13
-
173
-
-
0029794555
-
Targeted disruption of the murine tissue factor gene results in embryonic lethality
-
Toomey J., Kratzer K., Lasky N., Stanton J., Broze J. Targeted disruption of the murine tissue factor gene results in embryonic lethality. Blood 1996, 88:1583-1587.
-
(1996)
Blood
, vol.88
, pp. 1583-1587
-
-
Toomey, J.1
Kratzer, K.2
Lasky, N.3
Stanton, J.4
Broze, J.5
-
174
-
-
0030775316
-
Mice lacking factor VII develop normally but suffer fatal perinatal bleeding
-
Rosen E., Chan J., Idusogie E., et al. Mice lacking factor VII develop normally but suffer fatal perinatal bleeding. Nature 1997, 390:290-294.
-
(1997)
Nature
, vol.390
, pp. 290-294
-
-
Rosen, E.1
Chan, J.2
Idusogie, E.3
-
175
-
-
0033950264
-
Blood coagulation factor X defi ciency causes partial embryonic lethality and fatal neonatal bleeding in mice
-
Dewerchin M., Liang Z., Moons L., Carmeliet P., Castellino F., Collen D., Rosen E. Blood coagulation factor X defi ciency causes partial embryonic lethality and fatal neonatal bleeding in mice. Thromb Haemost 2000, 83:185-190.
-
(2000)
Thromb Haemost
, vol.83
, pp. 185-190
-
-
Dewerchin, M.1
Liang, Z.2
Moons, L.3
Carmeliet, P.4
Castellino, F.5
Collen, D.6
Rosen, E.7
-
176
-
-
0029093003
-
The absence of the blood clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system
-
Rosenberg R.D. The absence of the blood clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system. Thromb Haemost 1996, 74:52-57.
-
(1996)
Thromb Haemost
, vol.74
, pp. 52-57
-
-
Rosenberg, R.D.1
-
177
-
-
0029822021
-
The thrombin receptor is present in myoblasts and its expression is repressed upon fusion
-
Suidan H.S., Niclou S.P., Dreessen J., Beltraminelli N., Monard D. The thrombin receptor is present in myoblasts and its expression is repressed upon fusion. J Biol Chem 1996, 271:29162-29169.
-
(1996)
J Biol Chem
, vol.271
, pp. 29162-29169
-
-
Suidan, H.S.1
Niclou, S.P.2
Dreessen, J.3
Beltraminelli, N.4
Monard, D.5
-
178
-
-
0030841124
-
Protease-activated G protein-coupled receptors on human platelets and endothelial cells
-
Brass L.F., Molino M. Protease-activated G protein-coupled receptors on human platelets and endothelial cells. Thromb Haemost 1997, 78:234-241.
-
(1997)
Thromb Haemost
, vol.78
, pp. 234-241
-
-
Brass, L.F.1
Molino, M.2
-
179
-
-
0028239957
-
Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development
-
Soifer S., Peters K., O'Keefe J., Coughlin S.R. Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development. Am J Pathol 1991, 144:60-69.
-
(1991)
Am J Pathol
, vol.144
, pp. 60-69
-
-
Soifer, S.1
Peters, K.2
O'Keefe, J.3
Coughlin, S.R.4
-
180
-
-
0035979691
-
A role for thrombin receptor signaling in endothelial cells during embryonic development
-
Griffin C., Srinivasan Y., Zheng Y.-W., Huang W., Coughlin S.R. A role for thrombin receptor signaling in endothelial cells during embryonic development. Science 2001, 293:1666-1669.
-
(2001)
Science
, vol.293
, pp. 1666-1669
-
-
Griffin, C.1
Srinivasan, Y.2
Zheng, Y.-W.3
Huang, W.4
Coughlin, S.R.5
-
181
-
-
0028804964
-
Thrombin induces cell surface activation of gelatinase A in vascular endothelial cells: Physiological regulation of angiogenesis
-
Zucker S., Conner C., DiMassimo B., Ende H., Bahou W. Thrombin induces cell surface activation of gelatinase A in vascular endothelial cells: Physiological regulation of angiogenesis. J Biol Chem 1995, 270:23730-23738.
-
(1995)
J Biol Chem
, vol.270
, pp. 23730-23738
-
-
Zucker, S.1
Conner, C.2
DiMassimo, B.3
Ende, H.4
Bahou, W.5
-
182
-
-
0034743550
-
Factor VIIIa-induced gene expression: Potential implications in pathophysiology
-
Rao L., Pendurthi U. Factor VIIIa-induced gene expression: Potential implications in pathophysiology. Trends Cardiovasc Med 2001, 11:14-21.
-
(2001)
Trends Cardiovasc Med
, vol.11
, pp. 14-21
-
-
Rao, L.1
Pendurthi, U.2
-
183
-
-
0031041906
-
Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation
-
Molino M., Bainton D.F., Hoxie J., Coughlin S.R., Brass L.F. Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation. J Biol Chem 1997, 272:6011-6017.
-
(1997)
J Biol Chem
, vol.272
, pp. 6011-6017
-
-
Molino, M.1
Bainton, D.F.2
Hoxie, J.3
Coughlin, S.R.4
Brass, L.F.5
-
184
-
-
0029849778
-
Cleavage of the thrombin receptor: Identifi cation of potential activators and inactivators
-
Parry M., Myles T., Tschopp J., Stone S.R. Cleavage of the thrombin receptor: Identifi cation of potential activators and inactivators. Biochem J 1996, 320:335-341.
-
(1996)
Biochem J
, vol.320
, pp. 335-341
-
-
Parry, M.1
Myles, T.2
Tschopp, J.3
Stone, S.R.4
-
185
-
-
0028843436
-
Contrasting effects of thrombin and the thrombin receptor peptide, SFLLRN, on aggregation and release of 14C-serotinin by human platelets pretreated with chymotrypsin or serratia marcescens protease
-
Kinlough-Rathbone R.L., Perry D.W., Packham M.A. Contrasting effects of thrombin and the thrombin receptor peptide, SFLLRN, on aggregation and release of 14C-serotinin by human platelets pretreated with chymotrypsin or serratia marcescens protease. Thromb Haemost 1995, 73:122-125.
-
(1995)
Thromb Haemost
, vol.73
, pp. 122-125
-
-
Kinlough-Rathbone, R.L.1
Perry, D.W.2
Packham, M.A.3
-
186
-
-
0026441167
-
Thrombin receptor 14-amino acid peptide binds to endothelial cells and stimulates calcium transients
-
Tiruppathi C., Lum H., Andersen T.T., Fenton J.W., Malik A.B. Thrombin receptor 14-amino acid peptide binds to endothelial cells and stimulates calcium transients. Am J Physiol 1992, 263:L595-L601.
-
(1992)
Am J Physiol
, vol.263
-
-
Tiruppathi, C.1
Lum, H.2
Andersen, T.T.3
Fenton, J.W.4
Malik, A.B.5
-
187
-
-
0028009801
-
Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases
-
Ishii K., Chen J., Ishii M., Koch W.J., Freedman N.J., Lefkowitz R.J., Coughlin S.R. Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases. J Biol Chem 1994, 269:1125-1130.
-
(1994)
J Biol Chem
, vol.269
, pp. 1125-1130
-
-
Ishii, K.1
Chen, J.2
Ishii, M.3
Koch, W.J.4
Freedman, N.J.5
Lefkowitz, R.J.6
Coughlin, S.R.7
-
188
-
-
0028907488
-
Regulation of thrombin receptors on human umbilical vein endothelial cells
-
Woolkalis M.J., DeMelfi J., Blanchard N., Hoxie J.A., Brass L.F. Regulation of thrombin receptors on human umbilical vein endothelial cells. J Biol Chem 1995, 270:9868-9875.
-
(1995)
J Biol Chem
, vol.270
, pp. 9868-9875
-
-
Woolkalis, M.J.1
DeMelfi, J.2
Blanchard, N.3
Hoxie, J.A.4
Brass, L.F.5
-
189
-
-
0028959546
-
The functional thrombin receptor is associated with the plasma lemma and a large endosomal network in cultured human umbilical vein endothelial cells
-
Horvat R., Palade G. The functional thrombin receptor is associated with the plasma lemma and a large endosomal network in cultured human umbilical vein endothelial cells. J Cell Sci 1995, 108:1155-1164.
-
(1995)
J Cell Sci
, vol.108
, pp. 1155-1164
-
-
Horvat, R.1
Palade, G.2
-
190
-
-
0026782001
-
The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate both phosphoinositide hydrolysis and inhibit adenylyl cyclase
-
Hung D.T., Wong Y.H., Vu T.K.H., Coughlin S.R. The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate both phosphoinositide hydrolysis and inhibit adenylyl cyclase. J Biol Chem 1992, 353:20831-20834.
-
(1992)
J Biol Chem
, vol.353
, pp. 20831-20834
-
-
Hung, D.T.1
Wong, Y.H.2
Vu, T.K.H.3
Coughlin, S.R.4
-
191
-
-
0032910168
-
Organization and regulation of mitogen-activated protein kinase signaling pathways
-
Garrington T., Johnson G. Organization and regulation of mitogen-activated protein kinase signaling pathways. Current Opinion in Cell Biology 1999, 11:211-218.
-
(1999)
Current Opinion in Cell Biology
, vol.11
, pp. 211-218
-
-
Garrington, T.1
Johnson, G.2
-
192
-
-
0032568868
-
Direct stimulation of the guanine nucleotide exchange activity of p115RhoGEF by Gá
-
Hart M.J., et al. Direct stimulation of the guanine nucleotide exchange activity of p115RhoGEF by Gá. Science 1998, 280:2112-2114.
-
(1998)
Science
, vol.280
, pp. 2112-2114
-
-
Hart, M.J.1
-
193
-
-
0032569051
-
RhoGEF, a GTPase-activating protein for Galpha2 and Galpha3
-
Kozasa T., et al. RhoGEF, a GTPase-activating protein for Galpha2 and Galpha3. Science 1998, 280:2109-2111.
-
(1998)
Science
, vol.280
, pp. 2109-2111
-
-
Kozasa, T.1
-
194
-
-
0033593667
-
Activation of G12/G13 results in shape change and rho/rho kinase-mediated myosin light chain phosphorylation in mouse platelets
-
Klages B., Brandt U., Simon M.I., Schultz G., Offermanns S. Activation of G12/G13 results in shape change and rho/rho kinase-mediated myosin light chain phosphorylation in mouse platelets. J Cell Biol 1999, 144:745-754.
-
(1999)
J Cell Biol
, vol.144
, pp. 745-754
-
-
Klages, B.1
Brandt, U.2
Simon, M.I.3
Schultz, G.4
Offermanns, S.5
-
195
-
-
0029090212
-
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
-
Stoyanov B., et al. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science 1995, 269:690-693.
-
(1995)
Science
, vol.269
, pp. 690-693
-
-
Stoyanov, B.1
-
196
-
-
0027945789
-
Crystal structure at 2.2. A resolution of the pleckstrin homology domain from human dynamin
-
Ferguson K., Lemmon M., Schlessinger J., Sigler P. Crystal structure at 2.2. A resolution of the pleckstrin homology domain from human dynamin. Cell 1994, 79:199-209.
-
(1994)
Cell
, vol.79
, pp. 199-209
-
-
Ferguson, K.1
Lemmon, M.2
Schlessinger, J.3
Sigler, P.4
-
197
-
-
0028286304
-
Solution structure of a pleckstrinhomology domain
-
Yoon H., Hajduk P., Petros A., Olejniczak E., Meadows R., Fesik S. Solution structure of a pleckstrinhomology domain. Nature 1994, 369:672-675.
-
(1994)
Nature
, vol.369
, pp. 672-675
-
-
Yoon, H.1
Hajduk, P.2
Petros, A.3
Olejniczak, E.4
Meadows, R.5
Fesik, S.6
-
198
-
-
0028021882
-
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
-
Harlan J., Hajduk P., Yoon H., Fesik S. Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature 1994, 371:168-170.
-
(1994)
Nature
, vol.371
, pp. 168-170
-
-
Harlan, J.1
Hajduk, P.2
Yoon, H.3
Fesik, S.4
-
199
-
-
0029117595
-
Thrombin receptor ligation and activated Rac uncap actin fi lament barbed ends through phosphoinositide synthesis in permeabilized human platelets
-
Hartwig J., Bokoch G., Carpenter C., Janmey P., Taylor L., Toker A., Stossel T. Thrombin receptor ligation and activated Rac uncap actin fi lament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell 1995, 82:643-653.
-
(1995)
Cell
, vol.82
, pp. 643-653
-
-
Hartwig, J.1
Bokoch, G.2
Carpenter, C.3
Janmey, P.4
Taylor, L.5
Toker, A.6
Stossel, T.7
-
200
-
-
0030877837
-
Signaling through G proteins in platelets to the integrins and beyond
-
Brass L.F., Manning D.R., Cichowski K., Abrams C. Signaling through G proteins in platelets to the integrins and beyond. Thromb Haemost 1997, 78:581-589.
-
(1997)
Thromb Haemost
, vol.78
, pp. 581-589
-
-
Brass, L.F.1
Manning, D.R.2
Cichowski, K.3
Abrams, C.4
-
201
-
-
0023792637
-
Purifi cation and characterization of membrane-bound phospholipase C specifi c for phosphoinositides from human platelets
-
Banno Y., Yada Y., Nozawa Y. Purifi cation and characterization of membrane-bound phospholipase C specifi c for phosphoinositides from human platelets. J Biol Chem 1988, 263:11459-11465.
-
(1988)
J Biol Chem
, vol.263
, pp. 11459-11465
-
-
Banno, Y.1
Yada, Y.2
Nozawa, Y.3
-
202
-
-
0027397544
-
Inositol trisphosphate and calcium signalling
-
Berridge M.J. Inositol trisphosphate and calcium signalling. Nature 1993, 361:315-325.
-
(1993)
Nature
, vol.361
, pp. 315-325
-
-
Berridge, M.J.1
-
203
-
-
0026468420
-
Inositol-lipidspecifi c phospholipase C isoenzymes and their differential regulation by receptors
-
Cockcroft S., Thomas G.M. Inositol-lipidspecifi c phospholipase C isoenzymes and their differential regulation by receptors. Biochem J 1992, 288:1-14.
-
(1992)
Biochem J
, vol.288
, pp. 1-14
-
-
Cockcroft, S.1
Thomas, G.M.2
-
204
-
-
0024403320
-
Studies of inositol phospholipid-specific phospholipase C
-
Rhee S.G., Suh P.G., Ryu S.H., Lee S.Y. Studies of inositol phospholipid-specific phospholipase C. Science 1989, 244:546-550.
-
(1989)
Science
, vol.244
, pp. 546-550
-
-
Rhee, S.G.1
Suh, P.G.2
Ryu, S.H.3
Lee, S.Y.4
-
205
-
-
0025759035
-
Multiple forms of phosphoinositide-specific phospholipase C and different modes of activation
-
Rhee S.G., Kim H., Suh P.G., Choi W.C. Multiple forms of phosphoinositide-specific phospholipase C and different modes of activation. Biochem Soc Trans 1991, 19:337-341.
-
(1991)
Biochem Soc Trans
, vol.19
, pp. 337-341
-
-
Rhee, S.G.1
Kim, H.2
Suh, P.G.3
Choi, W.C.4
-
206
-
-
0019859255
-
Differential activation of platelet phospholipases by thrombin and ionophore A23187
-
Rittenhous-Simmons S. Differential activation of platelet phospholipases by thrombin and ionophore A23187. J Biol Chem 1981, 256:4153-4155.
-
(1981)
J Biol Chem
, vol.256
, pp. 4153-4155
-
-
Rittenhous-Simmons, S.1
-
207
-
-
0019131727
-
Evidence that the effects of thrombin on arachidonate metabolism in cultured human endothelial cells are not mediated by a high affinity receptor
-
Lollar D., Owen W. Evidence that the effects of thrombin on arachidonate metabolism in cultured human endothelial cells are not mediated by a high affinity receptor. J Biol Chem 1980, 255:8031-8034.
-
(1980)
J Biol Chem
, vol.255
, pp. 8031-8034
-
-
Lollar, D.1
Owen, W.2
-
208
-
-
0023525653
-
Selective uptake of [3H] arachidonic acid into the dense tubular system of human platelet
-
Laposata M., Krueger C., Saffi tz J. Selective uptake of [3H] arachidonic acid into the dense tubular system of human platelet. Blood 1987, 70:832-837.
-
(1987)
Blood
, vol.70
, pp. 832-837
-
-
Laposata, M.1
Krueger, C.2
Saffi, T.J.3
-
209
-
-
0029911368
-
P38Mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2
-
Kramer R., Roberts E., Um S., Borsch-Haubold A., Watson S. p38Mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2. J Biol Chem 1996, 271:27723-27729.
-
(1996)
J Biol Chem
, vol.271
, pp. 27723-27729
-
-
Kramer, R.1
Roberts, E.2
Um, S.3
Borsch-Haubold, A.4
Watson, S.5
-
210
-
-
0030756508
-
Defective platelet activation in G alpha (q) -defi cient mice
-
Offermanns S., Toombs C.F., Hu Y.H., Simon M.I. Defective platelet activation in G alpha (q) -defi cient mice. Nature 1997, 389:183-186.
-
(1997)
Nature
, vol.389
, pp. 183-186
-
-
Offermanns, S.1
Toombs, C.F.2
Hu, Y.H.3
Simon, M.I.4
-
211
-
-
0028179510
-
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets
-
Offermanns S., Laugwitz K., Spicher K., Schultz G. G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proc Natl Acad Sci USA 1994, 91:504-508.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 504-508
-
-
Offermanns, S.1
Laugwitz, K.2
Spicher, K.3
Schultz, G.4
-
212
-
-
0031015426
-
Vascular system defects and impaired cell chemokinesis as a result of G á13 defi ciency
-
Offermanns S., Mancino V., Revel J.-P., Simon M.I. Vascular system defects and impaired cell chemokinesis as a result of G á13 defi ciency. Science 1997, 275:533-536.
-
(1997)
Science
, vol.275
, pp. 533-536
-
-
Offermanns, S.1
Mancino, V.2
Revel, J.-P.3
Simon, M.I.4
-
213
-
-
0030968580
-
Rho GTPases and signaling networks
-
Van Aelst L., D'Souza-Schorey C. Rho GTPases and signaling networks. Genes Dev 1997, 11:2295-2322.
-
(1997)
Genes Dev
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
D'Souza-Schorey, C.2
-
214
-
-
0034142240
-
Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor
-
Azim A., Barkalow K., Chou J., Hartwig J. Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor. Blood 2000, 95:959-964.
-
(2000)
Blood
, vol.95
, pp. 959-964
-
-
Azim, A.1
Barkalow, K.2
Chou, J.3
Hartwig, J.4
-
215
-
-
0032695772
-
The elegant platelet: Signals controlling actin assembly
-
Hartwig J., Barkalow K., Azim A., Italiano J. The elegant platelet: Signals controlling actin assembly. Thromb Haemost 1999, 82:392.
-
(1999)
Thromb Haemost
, vol.82
, pp. 392
-
-
Hartwig, J.1
Barkalow, K.2
Azim, A.3
Italiano, J.4
-
216
-
-
0028264058
-
Involvement of phosphoinositide 3-kinase in insulin-or IGF-1-induced membrane ruffl ing
-
Kotani K., Yonezawa K., Hara K., Ueda H., Kitamura Y., Sakaue H., Ando A., Chavanieu A., Calas B., Grigorescu F. Involvement of phosphoinositide 3-kinase in insulin-or IGF-1-induced membrane ruffl ing. EMBO J 1994, 13:2313-2321.
-
(1994)
EMBO J
, vol.13
, pp. 2313-2321
-
-
Kotani, K.1
Yonezawa, K.2
Hara, K.3
Ueda, H.4
Kitamura, Y.5
Sakaue, H.6
Ando, A.7
Chavanieu, A.8
Calas, B.9
Grigorescu, F.10
-
217
-
-
0031004866
-
Massive actin polymerization induced by phosphatidylinositol-4-phosphate 5-kinase in vivo
-
Yoshikazu S., Ishihara H., Kizuki N., Asano T., Oka Y., Yazaki Y. Massive actin polymerization induced by phosphatidylinositol-4-phosphate 5-kinase in vivo. J Biol Chem 1997, 272:7578-7581.
-
(1997)
J Biol Chem
, vol.272
, pp. 7578-7581
-
-
Yoshikazu, S.1
Ishihara, H.2
Kizuki, N.3
Asano, T.4
Oka, Y.5
Yazaki, Y.6
-
218
-
-
0029050557
-
Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation
-
Kovacsovics T., Bachelot C., Toker A., Vlahos C., Duckworth B., Cantley L., Hartwig J. Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation. J Biol Chem 1995, 270:11358-11366.
-
(1995)
J Biol Chem
, vol.270
, pp. 11358-11366
-
-
Kovacsovics, T.1
Bachelot, C.2
Toker, A.3
Vlahos, C.4
Duckworth, B.5
Cantley, L.6
Hartwig, J.7
-
219
-
-
0034611727
-
PAR3 is a cofactor for PAR4 activation by thrombin
-
Nakanishi-Matsui M., Zheng Y.W., Sulciner D., Weiss E., Ludeman M., Coughlin S. PAR3 is a cofactor for PAR4 activation by thrombin. Nature 2000, 404:609-613.
-
(2000)
Nature
, vol.404
, pp. 609-613
-
-
Nakanishi-Matsui, M.1
Zheng, Y.W.2
Sulciner, D.3
Weiss, E.4
Ludeman, M.5
Coughlin, S.6
-
220
-
-
0034618268
-
AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration
-
AbdAlla S., Lother H., Quitterer U. AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. Nature 2000, 407:94-98.
-
(2000)
Nature
, vol.407
, pp. 94-98
-
-
AbdAlla, S.1
Lother, H.2
Quitterer, U.3
-
221
-
-
0033559805
-
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
-
Kahn M.L., Nakanishi-Matsui M., Shapiro M.J., Ishihara H., Coughlin S.R. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest 1999, 103:879-887.
-
(1999)
J Clin Invest
, vol.103
, pp. 879-887
-
-
Kahn, M.L.1
Nakanishi-Matsui, M.2
Shapiro, M.J.3
Ishihara, H.4
Coughlin, S.R.5
-
222
-
-
0034625055
-
Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets
-
Covic L., Gresser A., Kuliopulos A. Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets. Biochemistry 2000, 39:5458-5467.
-
(2000)
Biochemistry
, vol.39
, pp. 5458-5467
-
-
Covic, L.1
Gresser, A.2
Kuliopulos, A.3
-
223
-
-
0020692503
-
Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: Additional evidence in support of GPIb as a platelet receptor for von Willebrand factor
-
Coller B.S., Peerschke E., Scudder L.E., Sullivan C. Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: Additional evidence in support of GPIb as a platelet receptor for von Willebrand factor. Blood 1983, 61:99-110.
-
(1983)
Blood
, vol.61
, pp. 99-110
-
-
Coller, B.S.1
Peerschke, E.2
Scudder, L.E.3
Sullivan, C.4
-
224
-
-
0030742894
-
Platelet GPIb-V-1X complex
-
Clemetson K.J. Platelet GPIb-V-1X complex. Thromb Haemost 2001, 78:266-270.
-
(2001)
Thromb Haemost
, vol.78
, pp. 266-270
-
-
Clemetson, K.J.1
-
225
-
-
0021918266
-
Thrombin binds to a high affinity ~900,000 Dalton site in human platelets
-
Harmon J., Jamieson G. Thrombin binds to a high affinity ~900,000 Dalton site in human platelets. Biochemistry 1985, 24:58-64.
-
(1985)
Biochemistry
, vol.24
, pp. 58-64
-
-
Harmon, J.1
Jamieson, G.2
-
226
-
-
0022870417
-
The glycocalicin portion of platelet glycoprotein Ib expresses both high and moderate affinity receptor sites for thrombin. A soluble radioreceptor assay for the interaction of thrombin with platelets
-
Harmon J., Jamieson G. The glycocalicin portion of platelet glycoprotein Ib expresses both high and moderate affinity receptor sites for thrombin. A soluble radioreceptor assay for the interaction of thrombin with platelets. J Biol Chem 1986, 261:13224-13229.
-
(1986)
J Biol Chem
, vol.261
, pp. 13224-13229
-
-
Harmon, J.1
Jamieson, G.2
-
227
-
-
0026317444
-
Function of glycoprotein 1ba in platelet activation induced by α-thrombin
-
DeMarco L., Mazzucato M., Masotti A., Fenton J., Ruggeri Z. Function of glycoprotein 1ba in platelet activation induced by α-thrombin. J Biol Chem 1991, 265:23776.
-
(1991)
J Biol Chem
, vol.265
, pp. 23776
-
-
DeMarco, L.1
Mazzucato, M.2
Masotti, A.3
Fenton, J.4
Ruggeri, Z.5
-
228
-
-
0028181751
-
Localization and characterization of an alphathrombin-binding site on platelet glycoprotein Ib alpha
-
DeMarco L., Mazzucato M., Masotti A., Ruggeri Z.M. Localization and characterization of an alphathrombin-binding site on platelet glycoprotein Ib alpha. J Biol Chem 1994, 269:6478-6484.
-
(1994)
J Biol Chem
, vol.269
, pp. 6478-6484
-
-
DeMarco, L.1
Mazzucato, M.2
Masotti, A.3
Ruggeri, Z.M.4
-
229
-
-
0029963871
-
Mocarhagin, a novel cobra venom metalloproteinase, cleaves the platelet von Willebrand factor receptor glycoprotein Ibá. Identifi cation of the sulfated tyrosine/anionic sequence Tyr-276-Glu-282 of glycoprotein Ibá as a binding site for von Willebrand factor and α-thrombin
-
Ward C.M., Andrews R.K., Smith A.I., Berndt M.C. Mocarhagin, a novel cobra venom metalloproteinase, cleaves the platelet von Willebrand factor receptor glycoprotein Ibá. Identifi cation of the sulfated tyrosine/anionic sequence Tyr-276-Glu-282 of glycoprotein Ibá as a binding site for von Willebrand factor and α-thrombin. Biochemistry 1996, 35:4929-4938.
-
(1996)
Biochemistry
, vol.35
, pp. 4929-4938
-
-
Ward, C.M.1
Andrews, R.K.2
Smith, A.I.3
Berndt, M.C.4
-
230
-
-
0031893823
-
Characterization of the initial α-thrombin interaction with glycoprotein Ibá in relation to platelet activation
-
Mazzucato M., DeMarco L., Masotti A., Pradella P., Bahou W.F., Ruggeri Z.M. Characterization of the initial α-thrombin interaction with glycoprotein Ibá in relation to platelet activation. J Biol Chem 1998, 273:1880-1887.
-
(1998)
J Biol Chem
, vol.273
, pp. 1880-1887
-
-
Mazzucato, M.1
DeMarco, L.2
Masotti, A.3
Pradella, P.4
Bahou, W.F.5
Ruggeri, Z.M.6
-
231
-
-
0028940892
-
Identi-fi cation of three tyrosine residues of glycoprotein Ibá with distinct roles in von Willebrand factor and α-thrombin binding
-
Marchese P., Murata M., Mazzucato M., Pradella P., DeMarco L., Ware J.A., Ruggeri Z.M. Identi-fi cation of three tyrosine residues of glycoprotein Ibá with distinct roles in von Willebrand factor and α-thrombin binding. J Biol Chem 1995, 270:9571-9578.
-
(1995)
J Biol Chem
, vol.270
, pp. 9571-9578
-
-
Marchese, P.1
Murata, M.2
Mazzucato, M.3
Pradella, P.4
DeMarco, L.5
Ware, J.A.6
Ruggeri, Z.M.7
-
232
-
-
0033534612
-
The platelet high affinity binding site for thrombin mimics hirudin, modulates thrombin-induced platelet activation, and is distinct from the glycoprotein Ib-IX-V complex
-
Hayes K., Tracy P.B. The platelet high affinity binding site for thrombin mimics hirudin, modulates thrombin-induced platelet activation, and is distinct from the glycoprotein Ib-IX-V complex. J Biol Chem 1999, 274:972-980.
-
(1999)
J Biol Chem
, vol.274
, pp. 972-980
-
-
Hayes, K.1
Tracy, P.B.2
-
233
-
-
0018190052
-
Platelet glycocalicin interaction with thrombin and role as thrombin receptor of the platelet surface
-
Okumura T., Hasitz M., Jamieson G.A. Platelet glycocalicin interaction with thrombin and role as thrombin receptor of the platelet surface. J Biol Chem 1978, 253:3435-3443.
-
(1978)
J Biol Chem
, vol.253
, pp. 3435-3443
-
-
Okumura, T.1
Hasitz, M.2
Jamieson, G.A.3
-
234
-
-
0030062966
-
2+] induced by alpha-thrombin
-
2+] induced by alpha-thrombin. Biochemistry 1996, 35:906-914.
-
(1996)
Biochemistry
, vol.35
, pp. 906-914
-
-
Greco, N.J.1
Tandon, N.N.2
Jones, G.D.3
Kornhauser, R.4
Jackson, B.5
Yammamoton, N.6
Tanoue, K.7
Jamieson, G.A.8
-
235
-
-
0031029996
-
Binding of thrombin to the Gprotein-linked receptor, and not to glycoprotein Ib, precedes thrombin-mediated platelet activation
-
Liu L., Freedman J., Hornstein A., Fenton J.W., Song Y., Ofosu F.A. Binding of thrombin to the Gprotein-linked receptor, and not to glycoprotein Ib, precedes thrombin-mediated platelet activation. J Biol Chem 1997, 272:1997-2004.
-
(1997)
J Biol Chem
, vol.272
, pp. 1997-2004
-
-
Liu, L.1
Freedman, J.2
Hornstein, A.3
Fenton, J.W.4
Song, Y.5
Ofosu, F.A.6
-
236
-
-
0026534991
-
The thrombin high-affinity binding site on platelets is a negative regulator of thrombin-induced platelet acivation. Structure-function studies using two mutant thrombins, Quick I and Quick II
-
Leong L., Henriksen R., Kermode J., Rittenhouse S.E., Tracy P.B. The thrombin high-affinity binding site on platelets is a negative regulator of thrombin-induced platelet acivation. Structure-function studies using two mutant thrombins, Quick I and Quick II. Biochemistry 1992, 31:2567-2576.
-
(1992)
Biochemistry
, vol.31
, pp. 2567-2576
-
-
Leong, L.1
Henriksen, R.2
Kermode, J.3
Rittenhouse, S.E.4
Tracy, P.B.5
-
237
-
-
0029897983
-
Defective thrombin-induced calcium changes and aggregation of Bernard-Soulier platelets are not associated with defi cient moderate-affinity receptors
-
McNicol A., Sutherland M., Zou R., Dronin J. Defective thrombin-induced calcium changes and aggregation of Bernard-Soulier platelets are not associated with defi cient moderate-affinity receptors. Arterioscl Thromb Vasc Biol 1996, 16:628-632.
-
(1996)
Arterioscl Thromb Vasc Biol
, vol.16
, pp. 628-632
-
-
McNicol, A.1
Sutherland, M.2
Zou, R.3
Dronin, J.4
-
239
-
-
0017408374
-
Platelet plasma membrane glycoproteins. Identifi cation of a proteolytic substrate for thrombin
-
Phillips D.R., Agin P.P. Platelet plasma membrane glycoproteins. Identifi cation of a proteolytic substrate for thrombin. Biochem Biophys Res Commun 1977, 75:940-947.
-
(1977)
Biochem Biophys Res Commun
, vol.75
, pp. 940-947
-
-
Phillips, D.R.1
Agin, P.P.2
-
240
-
-
0018409185
-
Action of thrombin on surface glycoproteins of human platelets
-
Mosher D., Vaheri A., Choate J., Gahmberg C. Action of thrombin on surface glycoproteins of human platelets. Blood 1979, 53:437-445.
-
(1979)
Blood
, vol.53
, pp. 437-445
-
-
Mosher, D.1
Vaheri, A.2
Choate, J.3
Gahmberg, C.4
-
241
-
-
0022254372
-
Glycoprotein V hydrolysis by thrombin. Lack of correlation with secretion
-
White G.C.I., Krupp C. Glycoprotein V hydrolysis by thrombin. Lack of correlation with secretion. Thromb Res 1985, 38:641-648.
-
(1985)
Thromb Res
, vol.38
, pp. 641-648
-
-
White, G.C.I.1
Krupp, C.2
-
242
-
-
0022499525
-
Glycoprotein V is not the thrombin activation receptor on human blood platelets
-
Bienz D., Schnippering W., Clemetson K.J. Glycoprotein V is not the thrombin activation receptor on human blood platelets. Blood 1986, 68:720-725.
-
(1986)
Blood
, vol.68
, pp. 720-725
-
-
Bienz, D.1
Schnippering, W.2
Clemetson, K.J.3
-
243
-
-
0033539692
-
Increased thrombin responsiveness in platelets from mice lacking glycoprotein
-
Ramakrishnan V., Reeves P., DeGuzman F., Deshpande U., Madrid-Ministri K., DuBridge R., Philipps D. Increased thrombin responsiveness in platelets from mice lacking glycoprotein. Proc Natl Acad Sci USA 1999, 96:13336-13341.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13336-13341
-
-
Ramakrishnan, V.1
Reeves, P.2
DeGuzman, F.3
Deshpande, U.4
Madrid-Ministri, K.5
DuBridge, R.6
Philipps, D.7
-
244
-
-
0035852682
-
A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V
-
Ramakrishnan V., DeGuzman F., Bao M., Hall S., Leung L.L., Philipps D. A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V. Proc Natl Acad Sci USA 2001, 98:1823-1828.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1823-1828
-
-
Ramakrishnan, V.1
DeGuzman, F.2
Bao, M.3
Hall, S.4
Leung, L.L.5
Philipps, D.6
-
245
-
-
0026457543
-
A stable metabolite, Arg-Pro-Pro-Gly-Phe of bradykinin in the degradation pathway in human plasma
-
Shima C., Majima M., Katori M. A stable metabolite, Arg-Pro-Pro-Gly-Phe of bradykinin in the degradation pathway in human plasma. Japan J Pharmacol 1992, 60:111-119.
-
(1992)
Japan J Pharmacol
, vol.60
, pp. 111-119
-
-
Shima, C.1
Majima, M.2
Katori, M.3
-
246
-
-
0026090569
-
High molecular weight kininogen inhibits thrombininduced platelet aggregation and cleavage of aggregin by inhibiting binding of thrombin to platelets
-
Puri R., Zhou F., Hu C., Colman R., Colman R. High molecular weight kininogen inhibits thrombininduced platelet aggregation and cleavage of aggregin by inhibiting binding of thrombin to platelets. Blood 1991, 77:500-507.
-
(1991)
Blood
, vol.77
, pp. 500-507
-
-
Puri, R.1
Zhou, F.2
Hu, C.3
Colman, R.4
Colman, R.5
-
247
-
-
0025834590
-
Low molecular weight kininogen binds to platelets to modulate thrombin-induced platelet activzation
-
Meloni F., Schmaier A. Low molecular weight kininogen binds to platelets to modulate thrombin-induced platelet activzation. J Biol Chem 1991, 266:6786-6794.
-
(1991)
J Biol Chem
, vol.266
, pp. 6786-6794
-
-
Meloni, F.1
Schmaier, A.2
-
248
-
-
0029814343
-
Bradykinin and its metabolite, Arg-Pro-Pro-Gly-Phe, and selective inhibitors of alpha-thrombin induced platelet activation
-
Hasan A., Amenta S., Schmaier A. Bradykinin and its metabolite, Arg-Pro-Pro-Gly-Phe, and selective inhibitors of alpha-thrombin induced platelet activation. Circulation 1996, 94:517-528.
-
(1996)
Circulation
, vol.94
, pp. 517-528
-
-
Hasan, A.1
Amenta, S.2
Schmaier, A.3
-
249
-
-
0029758276
-
Development of potent thrombin receptor antagonist peptides
-
Bernatowicz M., Klimas C., Hartl K., Peluso M., Alegretto N., Seiler S.M. Development of potent thrombin receptor antagonist peptides. J Med Chem 1996, 39:4879-4887.
-
(1996)
J Med Chem
, vol.39
, pp. 4879-4887
-
-
Bernatowicz, M.1
Klimas, C.2
Hartl, K.3
Peluso, M.4
Alegretto, N.5
Seiler, S.M.6
-
250
-
-
13044257730
-
Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tetheredligand receptor
-
Andrade-Gordon P., Maryanoff B.E., Derian C.K., Zhang H.C., Addo M.F., Darrow A.L., Eckardt A.J., Hoekstra W.J., McComsey D.F., Oksenberg D., Reynolds E.E., Santulli R.J., Scarborough R., Smit E.M., White K.B. Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tetheredligand receptor. Proc Natl Acad Sci USA 1999, 96:12257-12262.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12257-12262
-
-
Andrade-Gordon, P.1
Maryanoff, B.E.2
Derian, C.K.3
Zhang, H.C.4
Addo, M.F.5
Darrow, A.L.6
Eckardt, A.J.7
Hoekstra, W.J.8
McComsey, D.F.9
Oksenberg, D.10
Reynolds, E.E.11
Santulli, R.J.12
Scarborough, R.13
Smit, E.M.14
White, K.B.15
-
251
-
-
0037154270
-
Activation and inhibition of G protein-coupled receptors by cell-penetrating membranetethered peptides
-
Covic L., Gresser A.L., Talavera J., Swift S., Kuliopulos A. Activation and inhibition of G protein-coupled receptors by cell-penetrating membranetethered peptides. Proc Natl Acad Sci USA 2002, 99:643-648.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 643-648
-
-
Covic, L.1
Gresser, A.L.2
Talavera, J.3
Swift, S.4
Kuliopulos, A.5
-
252
-
-
0036797590
-
Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
-
Covic L., Misra M., Badar J., Singh C., Kuliopulos A. Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation. Nat Med 2002, 8:1161-1165.
-
(2002)
Nat Med
, vol.8
, pp. 1161-1165
-
-
Covic, L.1
Misra, M.2
Badar, J.3
Singh, C.4
Kuliopulos, A.5
-
253
-
-
0026575003
-
Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis
-
Cotecchia S., Ostrowski J., Kjelsberg M.A., Caron M.G., Lefkowitz R.J. Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis. J Biol Chem 1992, 267:1633-1639.
-
(1992)
J Biol Chem
, vol.267
, pp. 1633-1639
-
-
Cotecchia, S.1
Ostrowski, J.2
Kjelsberg, M.A.3
Caron, M.G.4
Lefkowitz, R.J.5
-
254
-
-
0031002654
-
The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors
-
Verall S., Ishii M., Wang M., Tram T., Coughlin S. The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors. J Biol Chem 1997, 272:6898-6902.
-
(1997)
J Biol Chem
, vol.272
, pp. 6898-6902
-
-
Verall, S.1
Ishii, M.2
Wang, M.3
Tram, T.4
Coughlin, S.5
-
255
-
-
0034616021
-
Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity
-
Rocheville M., Lange D.C., Kumar U., Patel S.C., Patel R.C., Patel Y.C. Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity. Science 2000, 288:154-157.
-
(2000)
Science
, vol.288
, pp. 154-157
-
-
Rocheville, M.1
Lange, D.C.2
Kumar, U.3
Patel, S.C.4
Patel, R.C.5
Patel, Y.C.6
-
256
-
-
0036797715
-
Attacked from within, blood thins
-
Bahou W.F. Attacked from within, blood thins. Nat Med 2002, 8:1082-1083.
-
(2002)
Nat Med
, vol.8
, pp. 1082-1083
-
-
Bahou, W.F.1
|