Evidence for selective effects of chronic hypertension on cerebral artery vasodilatation to protease-activated receptor-2 activation

Stroke

Volumn 30, Issue 9, 1999, Pages 1933-1941

  Sobey, Christopher G ^a   Moffatt, James D ^a   Cocks, Thomas M ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Basilar artery; Endothelium; Nitric oxide; Thrombin

Indexed keywords

ACETYLCHOLINE; ARGININE; BRADYKININ; NITRIC OXIDE; PROTEINASE; TRYPSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DILATATION; ARTICLE; BASILAR ARTERY; BRAIN ARTERY; BRAIN CIRCULATION; CONTROLLED STUDY; HYPERTENSION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; RAT;

EID: 0032867472     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.30.9.1933     Document Type: Article

References (44)

1. Vu T-KH, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 1991;64:1057-1068.
2. Gerszten RE, Chen J, Ishii M, Wang L, Nanevicz T, Turck CW, Vu T-KH, Coughlin SR. Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface. Nature. 1994;368: 648-651.
3. Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, Coughlin SR. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature. 1997:386:502-506.
4. Kahn ML, Zheng Y-W, Huang W, Bigornia V, Zeng D, Moff S, Farese RVJ, Tarn C, Coughlin SR. A dual thrombin receptor system for platelet activation. Nature. 1998:394:690-694.
5. Dery O, Corvera CD, Steinhoff M, Bunnelt NW. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol. 1998;274:CH29-C1452.
6. 2, in rat vascular and gastric muscle. Can J Physiol Phannacol. 1995:73:1203-1207.
7. Hwa JJ, Ghibaudi L, Williams P, Chintala M, Zhang R, Chatterjee M, Sybertz E. Evidence for the presence of a proteinase-activated receptor distinct from the thrombin receptor in vascular endothelial cells. Circ Res. 1996;78:581-588.
8. Molino M, Woolkalis MJ, Reavey-Cantwell J, Pratico D, Andrade-Gordon P, Barnathan ES, Brass LF. Endothelial cell thrombin receptors and PAR-2: two protease-activated receptors located in a single cellular environment. J Biol Cliem. 1997;272:11133-11141.
9. Emilsson K, Wahlestedt C, Sun M-K, Nystedt S, Owman C, Sundelin J. Vascular effects of proteinase-aclivatcd receptor2 agonist peptide. J Vasc Res. 1997:34:267-272.
10. Katusic ZS, Shepherd JT, Vanhoutte PM. Vasopressin causes endothelium-dependent relaxations of the canine basilar artery. Circ Res. 1984;55: 575-579.
11. White RP, Shirasawa Y, Robertson JT. Comparison of responses elicited by alpha-thrombin in isolated canine basilar, coronary, mesenteric, and renal arteries. Blood Vessels. 1984;2l:12-22.
12. Maramatsu I, Laniyonu A, Moore GJ, Hollenberg MD. Vascular actions of thrombin receptor peptide. Can J Physiol Phannacol. 1992;70: 996-1003.
13. Nystedt S, Emilsson K, Wahlestedt C, Sundelin J. Molecular cloning of a potential proteinase activated receptor. Proc Nail Acad Sei USA. 1994:91:9208-9212.
14. D'Andréa MR, Derian CK, Leturcq D, Baker SM, Brunmark A, Ling P, Darrow AL, Santulli RJ, Brass LF, Andrade-Gordon P. Characterization of protease-activated receptor-2 immunoreactivity in normal human tissues. J Histochem Cytochem. 1998:46:157-164.
15. Saifeddine M, Al-Ani B, Cheng C-H, Wang L, Hollenberg MD. Rat proteinase-activated receptor-2 (PAR-2): cDNA sequence and activity of receptor-derived peptides in gastric and vascular tissue. Br J Phannacol. 1996;118:521-530.
16. Hollenberg MD, Saifeddine M, Al-Ani B. Proteinase-activated receptor-2 in rat aorta: structural requirements for agonist activity of receptoractivating peptides. Molec Phannacol. 1996;49:229-233.
17. Hamilton JR, Nguyen PB, Cocks TM. Atypical protease-activated receptor mediates endothelium-dependent relaxation of human coronary arteries. Circ Res. 1998:82:1306-1311.
18. Moffatt JD, Cocks TM. Endothelium-dependent and -independent responses to protease-activated receptor-2 (PAR-2) activation in mouse isolated renal arteries. Br J Phannacol. 1998:125:591-594.
19. White RP. Comparison of the inhibitory effects of antithrombin HI, a2-macroglobulin, and thrombin in human basilar arteries: relevance to cerebral vasospasm. J Cereb Blood Flow Metab. 1987;7:68-73.
20. Hatake K, Wakabayashi I, Kakishita E, Hishida S. Impairment of endothelium-dependent relaxation in human basilar artery after subarachnoid hemorrhage. Stroke. 1992:23:1111-1117.
21. Sobey CG, Cocks TM. Activation of protease-activated receptor-2 (PAR-2) elicits nitric oxide-dependent dilatation of the basilar artery in vivo. Stroke. 1998:29:1439-1444.
22. Nystedt S, Ramakrishnan V, Sundelin J. The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells: comparison with the thrombin receptor. J Biol Chem. 1996:271: 14910-14915.
23. Faraci FM, Heistad DD. Regulation of the cerebral circulation: role of endothelium and potassium channels. Physiol Rev. 1998;78:53-97.
24. Lai FM, Cobuzzi A, Shepherd C, Tanikella T, Huffman A, Cervoni P. Endothelium-dependent basilar and aortic vascular responses in normotensive and coarctation hypertensive rats. Life Sei. 1989;45:607-614.
25. Màckert JL, Parsons AA, Wahl M, Schilling L. Mediation of endothelium-dependent relaxation: different response patterns in rat and rabbit basilar artery. Neural Res. 1997;19:521-526.
26. Mayhan WG. Impairment of endothelium-dependent dilatation of basilar artery during chronic hypertension. Am J Physiol. 1990;259: H1455-H1462.
27. Faraci FM, Heistad DD. Role of ATP-sensitive potassium channels in the basilar artery. Am J Physiol. 1993;264:H8-H13.
28. Sobey CG, Faraci FM. Effect of nitric oxide and potassium channel agonists and inhibitors on basilar artery diameter. Am J Physiol. 1997; 272:H256-H262.
29. Kitazono T, Faraci FM, Heistad DD. L-Arginine restores dilator responses of the basilar artery to acetylcholine during chronic hypertension. Hypertension. 1996:27:893-896.
30. Garland CJ, Plane F, Kemp BK, Cocks TM. Endothelium-dependent hyperpolarization: a role in the control of vascular tone. Trends Phannacol Sei. 1995;16:23-30.
31. Dora KA, Doyle MP, Duling BR. Elevation of intracellular calcium in smooth muscle causes endothelial cell generation of NO in arterioles. Proc Nail Acad Sei USA. 1997;94:6529-6534.
32. Laniyonu AA, Hollenberg MD. Vascular actions of thrombin receptorderived polypeptides: structure-activity profiles for contractile and relaxant effects in rat aorta. Br J Pharmacol. 1995;114:1680-1686.
33. Bono F, Lamarche I, Herbert JM. Induction of vascular smooth muscle cell growth by selective activation of the proteinase-activated receptor-2 (PAR-2). Biochem Biophys Res Commun. 1997;241:762-764.
34. Kitazono T, Heistad DD, Faraci FM. Enhanced responses of the basilar artery to activation of endothelin-B receptors in stroke-prone spontaneously hypertensive rats. Hypertension. 1995;25(pt l):490-494.
35. Nishimura Y, Usui H, Suzuki A, Kajimoto N, Yamanishi Y. Relaxant response of isolated basilar arteries to calcitonin gene-related peptide in stroke-prone spontaneously hypertensive rats. Jpn J Phannacol. 1992;59: 333-338.
36. Nishimura Y, Suzuki A. Relaxant effects of vasodilator peptides on isolated basilar arteries from stroke-prone spontaneously hypertensive rats. Clin Exp Phannacol Physiol. 1997;24:157-161.
37. Xu W-F, Anderson H, Whitmore TE, Presnell SR, Yee DP, Ching A, Gilbert T, Davie EW, Foster DC. Cloning and characterization of human protease activated receptor 4. Proc Natl Acad Sei USA. 1998;95: 6642-6646.
38. Edvinsson L, Cervos-Navaro J, Larsson L-I, Owman C, Ronnberg A-L. Regional distribution of mast cells containing histamine, dopamine, or 5-hydroxytryptamine in the mammalian brain. Neurology. 1977;27: 878-883.
39. Keller JT, Marfurt CF, Dimlich RVW, Tiemey BE. Sympathetic innervation of the rat supratentorial dura mater of the rat. J Comp Neural. 1989;290:310-321.
40. Schaeffer P, Mares A-M, Dol F, Bono F, Herbert J-M. Coagulation factor Xa induces endolhelium-dependent relaxations in rat aorta. Circ Res. 1997;81:824-828.
41. Cignarella A, Bertozzi D, Zaarour C, Puglisi L. Antithrombotie activity of nicardipine in spontaneously hypertensive rats. Phannacol Res. 1994;30: 273-280.
42. Kojima T, Doi K, Kishi M, Horiguchi Y. Comparison of plasma total plasmin activities in male and female hypertensive rats. Res Commun Mol Pathol Phannacol. 1995;88:233-236.
43. Lip GYH, Blann AD, Jones AF, Lip PL, Beevers DG. Relation of endothelium, thrombogenesis, and hemorheology in systemic hypertension to ethnicity and left ventricular hypertrophy. Am J Cordial. 1997;80:1566-1571.
44. Tomiyama H, Kimura Y, Mitsuhashi H, Kinouchi T, Yoshida H, Kushiro T, Doba N. Relationship between endothelial function and fibrinolysis in early hypertension. Hypertension. 1998;31(pt 2):321-327.