메뉴 건너뛰기




Volumn 99, Issue 5, 2000, Pages 417-427

Thrombin: A neuronal cell modulator

Author keywords

Nervous system; Neuronal degeneration; Neuronal development; PAR; Thrombin

Indexed keywords

CELL RECEPTOR; MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 1; PROTHROMBIN; THROMBIN; THROMBIN INHIBITOR; THROMBIN RECEPTOR;

EID: 0034283288     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(00)00300-5     Document Type: Review
Times cited : (25)

References (117)
  • 1
    • 0023517177 scopus 로고
    • Thrombin is a potent mitogen for rat astroblasts but not for oligodendroblasts and neuroblasts in primary culture
    • Perraud F, Besnard F, Sensenbrenner M, Labourdette G. Thrombin is a potent mitogen for rat astroblasts but not for oligodendroblasts and neuroblasts in primary culture. Int J Dev Neurosci 1987;5:181-8.
    • (1987) Int J Dev Neurosci , vol.5 , pp. 181-188
    • Perraud, F.1    Besnard, F.2    Sensenbrenner, M.3    Labourdette, G.4
  • 2
    • 0011811083 scopus 로고
    • Thrombin modulates and reverses neuroblastoma neurite outgrowth
    • Gurwitz D, Cunningham D. Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc Natl Acad Sci USA 1988;85:3440-4.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 3440-3444
    • Gurwitz, D.1    Cunningham, D.2
  • 3
    • 0025189336 scopus 로고
    • Neurite out-growth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition
    • Gurwitz D, Cunningham D. Neurite out-growth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition. J Cell Physiol 1990;142:155-62.
    • (1990) J Cell Physiol , vol.142 , pp. 155-162
    • Gurwitz, D.1    Cunningham, D.2
  • 4
    • 0026519282 scopus 로고
    • Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors
    • Suidan HS, Stone SR, Hemmings BA, Monard D. Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors. Neuron 1992;8:363-75.
    • (1992) Neuron , vol.8 , pp. 363-375
    • Suidan, H.S.1    Stone, S.R.2    Hemmings, B.A.3    Monard, D.4
  • 5
    • 0028085095 scopus 로고
    • Thrombin receptor peptides induce changes in neonatal murine astrocytes in culture
    • Beecher KL, Andersen TT, Fenton JWII, Festoff BW. Thrombin receptor peptides induce changes in neonatal murine astrocytes in culture. J Neurosci Res 1994;37:108-15.
    • (1994) J Neurosci Res , vol.37 , pp. 108-115
    • Beecher, K.L.1    Andersen, T.T.2    Fenton, J.W.I.I.3    Festoff, B.W.4
  • 6
    • 17344365478 scopus 로고    scopus 로고
    • Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation
    • Turgeon VL, Lloyd ED, Wang S, Festoff BW, Houenou LJ. Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation. J Neurosci 1998;18:6882-91.
    • (1998) J Neurosci , vol.18 , pp. 6882-6891
    • Turgeon, V.L.1    Lloyd, E.D.2    Wang, S.3    Festoff, B.W.4    Houenou, L.J.5
  • 7
    • 0032945017 scopus 로고    scopus 로고
    • Activation of the protease-activated thrombin receptor (PAR)-1 induces motoneuron degeneration in the developing avian embryo
    • Turgeon VL, Milligan CE, Houenou LJ. Activation of the protease-activated thrombin receptor (PAR)-1 induces motoneuron degeneration in the developing avian embryo. J Neuropath Exper Neurol 1999;58:499-504.
    • (1999) J Neuropath Exper Neurol , vol.58 , pp. 499-504
    • Turgeon, V.L.1    Milligan, C.E.2    Houenou, L.J.3
  • 8
    • 0023851616 scopus 로고
    • A glia-derived nexin promotes neurite outgrowth in cultured chick sympathetic neurons
    • Zurn AD, Nick H, Monard D. A glia-derived nexin promotes neurite outgrowth in cultured chick sympathetic neurons. Dev Neurosci 1988;10:17-24.
    • (1988) Dev Neurosci , vol.10 , pp. 17-24
    • Zurn, A.D.1    Nick, H.2    Monard, D.3
  • 9
    • 0024842164 scopus 로고
    • Purification of a serum factor which reverses dibutyryl cAMP induced differentiation
    • Grabham PW, Grand RJ, Gallimore PH. Purification of a serum factor which reverses dibutyryl cAMP induced differentiation. Cell Signal. 1989;1:269-81.
    • (1989) Cell Signal. , vol.1 , pp. 269-281
    • Grabham, P.W.1    Grand, R.J.2    Gallimore, P.H.3
  • 10
    • 0024465346 scopus 로고
    • Modulation of morphological differentiation of human neuroepithelial cells by serine proteases: Independent from blood coagulation
    • Grand RJ, Grabham PW, Gallimore MJ, Gallimore PH. Modulation of morphological differentiation of human neuroepithelial cells by serine proteases: independent from blood coagulation. EMBO 1989;8:2209-15.
    • (1989) EMBO , vol.8 , pp. 2209-2215
    • Grand, R.J.1    Grabham, P.W.2    Gallimore, M.J.3    Gallimore, P.H.4
  • 11
    • 0028027214 scopus 로고
    • Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid beta-protein precursor
    • Davis-Salinas J, Saporito-Irwin SM, Donovan FM, Cunningham DD, Van Nostrand WE. Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid beta-protein precursor. J Biol Chem 1994;269:22623-7.
    • (1994) J Biol Chem , vol.269 , pp. 22623-22627
    • Davis-Salinas, J.1    Saporito-Irwin, S.M.2    Donovan, F.M.3    Cunningham, D.D.4    Van Nostrand, W.E.5
  • 13
    • 0026520206 scopus 로고
    • Involvement of the 'tethered-ligand' receptor in thrombin inhibition of platelet adenylate cyclase
    • Seiler SM, Michel IM, Fenton JWII. Involvement of the 'tethered-ligand' receptor in thrombin inhibition of platelet adenylate cyclase. Biochem Biophys Res Comm 1992;182:1296-1302.
    • (1992) Biochem Biophys Res Comm , vol.182 , pp. 1296-1302
    • Seiler, S.M.1    Michel, I.M.2    Fenton, J.W.I.I.3
  • 14
    • 0027510492 scopus 로고
    • Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: A possible involvement of thrombin
    • Neveu I, Jehan F, Jandrot-Perrus M, Wion D, Brachet P. Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: a possible involvement of thrombin. J Neurochem 1993;60:858-67.
    • (1993) J Neurochem , vol.60 , pp. 858-867
    • Neveu, I.1    Jehan, F.2    Jandrot-Perrus, M.3    Wion, D.4    Brachet, P.5
  • 15
    • 0024383352 scopus 로고
    • Differential phenotypic expression induced in cultured rat astroblasts by acidic fibroblast growth factor, epidermal growth factor and thrombin
    • Loret C, Sensenbrenner M, Labourdette G. Differential phenotypic expression induced in cultured rat astroblasts by acidic fibroblast growth factor, epidermal growth factor and thrombin. J Biol Chem 1989;264:8319-27.
    • (1989) J Biol Chem , vol.264 , pp. 8319-8327
    • Loret, C.1    Sensenbrenner, M.2    Labourdette, G.3
  • 16
    • 0025255579 scopus 로고
    • Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1
    • Cavanaugh KP, Gurwitz D, Cunningham DD, Bradshaw RA. Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J Neurochem 1990;54:1735-43.
    • (1990) J Neurochem , vol.54 , pp. 1735-1743
    • Cavanaugh, K.P.1    Gurwitz, D.2    Cunningham, D.D.3    Bradshaw, R.A.4
  • 18
    • 0028239957 scopus 로고
    • Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development
    • Soifer SJ, Peters KG, O'Keefe J, Coughlin SR. Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development. Amer J Pathol 1994;144:60-9.
    • (1994) Amer J Pathol , vol.144 , pp. 60-69
    • Soifer, S.J.1    Peters, K.G.2    O'Keefe, J.3    Coughlin, S.R.4
  • 19
    • 0022924096 scopus 로고
    • Thrombin interaction with central nervous system tissue and implication of these interactions
    • Means ED, Anderson DK. Thrombin interaction with central nervous system tissue and implication of these interactions. Annals NY Acad Sci 1986;485:314-22.
    • (1986) Annals NY Acad Sci , vol.485 , pp. 314-322
    • Means, E.D.1    Anderson, D.K.2
  • 20
    • 0028914068 scopus 로고
    • Cellular localization of thrombin receptor mRNA in rat brain: Expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA
    • Weinstein JR, Gold SJ, Cunningham DD, Gall CM. Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J Neurosci 1995;15:2906-19.
    • (1995) J Neurosci , vol.15 , pp. 2906-2919
    • Weinstein, J.R.1    Gold, S.J.2    Cunningham, D.D.3    Gall, C.M.4
  • 21
    • 0021083331 scopus 로고
    • Thrombin binding to human brain and spinal cord
    • McKinney M, Snider RM, Richelson E. Thrombin binding to human brain and spinal cord. May Clin Proc 1983;58:829-31.
    • (1983) May Clin Proc , vol.58 , pp. 829-831
    • McKinney, M.1    Snider, R.M.2    Richelson, E.3
  • 22
    • 0026748742 scopus 로고
    • Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers
    • Jalink K, Moolenaar WH. Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers. J Cell Biol 1992;118:411-9.
    • (1992) J Cell Biol , vol.118 , pp. 411-419
    • Jalink, K.1    Moolenaar, W.H.2
  • 23
    • 0029072476 scopus 로고
    • Exogenous thrombin inhibits neuritogenesis in cultured neuroblastoma cells but not in rat hippocampal neurons
    • Brewer G. Exogenous thrombin inhibits neuritogenesis in cultured neuroblastoma cells but not in rat hippocampal neurons. Brain Res 1995;683:258-63.
    • (1995) Brain Res , vol.683 , pp. 258-263
    • Brewer, G.1
  • 24
    • 0029938079 scopus 로고    scopus 로고
    • Thrombin causes cell spreading and redistribution of β-amyloid immunoreactivity in cultured hippocampal neurons
    • Brewer GJ. Thrombin causes cell spreading and redistribution of β-amyloid immunoreactivity in cultured hippocampal neurons. J Neurochem 1996;67:119-30.
    • (1996) J Neurochem , vol.67 , pp. 119-130
    • Brewer, G.J.1
  • 25
    • 0026782001 scopus 로고
    • The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase
    • Hung DT, Wong YH, Vu T-KH, Coughlin SR. The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase. J Biol Chem 1992;267:20831-4.
    • (1992) J Biol Chem , vol.267 , pp. 20831-20834
    • Hung, D.T.1    Wong, Y.H.2    Vu, T.-K.H.3    Coughlin, S.R.4
  • 27
    • 16944366731 scopus 로고    scopus 로고
    • Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities
    • Donovan FM, Pike CJ, Cotman CW, Cunningham DD. Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. J Neurosci 1997;15:5316-26.
    • (1997) J Neurosci , vol.15 , pp. 5316-5326
    • Donovan, F.M.1    Pike, C.J.2    Cotman, C.W.3    Cunningham, D.D.4
  • 28
    • 0030848953 scopus 로고    scopus 로고
    • Thrombin receptor on rat primary hippocampal neurons: Coupled calcium and cAMP responses
    • Yang Y, Haruhiko A, Fenton JWII, Brewer G. Thrombin receptor on rat primary hippocampal neurons: coupled calcium and cAMP responses. Brain Res 1997;761:11-8.
    • (1997) Brain Res , vol.761 , pp. 11-18
    • Yang, Y.1    Haruhiko, A.2    Fenton, J.W.I.I.3    Brewer, G.4
  • 29
    • 0033573465 scopus 로고    scopus 로고
    • Thrombin-induced growth cone collapse: Involvement of phospholipase A2 and eicosanoid generation
    • De la Houssaye BA, Mikule K, Nikolic D, Pfenninger KH. Thrombin-induced growth cone collapse: involvement of phospholipase A2 and eicosanoid generation. J Neurosci 1999;19:10843-55.
    • (1999) J Neurosci , vol.19 , pp. 10843-10855
    • De La Houssaye, B.A.1    Mikule, K.2    Nikolic, D.3    Pfenninger, K.H.4
  • 30
    • 0026002929 scopus 로고
    • Production of thrombin and antithrombin III by brain and astroglial cell cultures
    • Deschepper CF, Bigorma V, Berens ME, Lapointe MC. Production of thrombin and antithrombin III by brain and astroglial cell cultures. Mol Brain Res 1991;11:355-8.
    • (1991) Mol Brain Res , vol.11 , pp. 355-358
    • Deschepper, C.F.1    Bigorma, V.2    Berens, M.E.3    Lapointe, M.C.4
  • 31
    • 0018311434 scopus 로고
    • The role of serine proteases in the blood coagulation cascade
    • Davie EW, Fujikawa K, Kurachi K, Kisiel W. The role of serine proteases in the blood coagulation cascade. Adv Enzymol Res 1989;48:277-318.
    • (1989) Adv Enzymol Res , vol.48 , pp. 277-318
    • Davie, E.W.1    Fujikawa, K.2    Kurachi, K.3    Kisiel, W.4
  • 32
    • 0033041111 scopus 로고    scopus 로고
    • PAR-1 type thrombin receptors are involved in thrombin-induced calcium signaling in human meningioma cells
    • Kaufman R, Patt S, Kraft R, Zieger M, Henklein P, Neupert G, Nowak G. PAR-1 type thrombin receptors are involved in thrombin-induced calcium signaling in human meningioma cells. J Neurooncol 1999;42:131-6.
    • (1999) J Neurooncol , vol.42 , pp. 131-136
    • Kaufman, R.1    Patt, S.2    Kraft, R.3    Zieger, M.4    Henklein, P.5    Neupert, G.6    Nowak, G.7
  • 33
    • 0021227227 scopus 로고
    • Activation of cyclic nucleotide formation in murine neuroblastoma N1E-115 cells by modified human thrombin
    • Snider RM, McKinney MJ, Fenton JWII, Richelson E. Activation of cyclic nucleotide formation in murine neuroblastoma N1E-115 cells by modified human thrombin. J Biol Chem 1984;259:9031-78.
    • (1984) J Biol Chem , vol.259 , pp. 9031-9078
    • Snider, R.M.1    McKinney, M.J.2    Fenton, J.W.I.I.3    Richelson, E.4
  • 35
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mecha-nism of receptor activation
    • Vu TH, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mecha-nism of receptor activation. Cell 1991;64:1057-68.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.H.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 36
    • 0033969081 scopus 로고    scopus 로고
    • Determination of the putative binding sites for thrombin receptor activating peptide through a hydropathic complementary approach
    • Suttner J, Dyr JE, Doleckova L. Determination of the putative binding sites for thrombin receptor activating peptide through a hydropathic complementary approach. Thromb Haemost 2000;83:165-70.
    • (2000) Thromb Haemost , vol.83 , pp. 165-170
    • Suttner, J.1    Dyr, J.E.2    Doleckova, L.3
  • 37
    • 0030829885 scopus 로고    scopus 로고
    • The role of thrombin-like serine proteases in the development, plasticity and pathology of the nervous system
    • Turgeon VL and Houenou J. The role of thrombin-like serine proteases in the development, plasticity and pathology of the nervous system. Brain Res Rev 1997;25:85-93.
    • (1997) Brain Res Rev , vol.25 , pp. 85-93
    • Turgeon, V.L.1    Houenou, J.2
  • 38
    • 0033071821 scopus 로고    scopus 로고
    • Thrombin and trypsin receptors: The same mechanism of signaling on cellular surfaces
    • Olejar T, Nouza K. Thrombin and trypsin receptors: the same mechanism of signaling on cellular surfaces. Bratisl Lek Listy 1999;100:75-9.
    • (1999) Bratisl Lek Listy , vol.100 , pp. 75-79
    • Olejar, T.1    Nouza, K.2
  • 39
    • 0033001930 scopus 로고    scopus 로고
    • Proteolytically activated receptor-3. A member of an emerging gene family of protease receptors expressed on vascular endothelial cells and platelets
    • Cupit LD, Schmidt VA, Bahou WF. Proteolytically activated receptor-3. A member of an emerging gene family of protease receptors expressed on vascular endothelial cells and platelets. Trends Cardiovas Med 1999;9:42-8.
    • (1999) Trends Cardiovas Med , vol.9 , pp. 42-48
    • Cupit, L.D.1    Schmidt, V.A.2    Bahou, W.F.3
  • 40
    • 0008123513 scopus 로고
    • Regulation of phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by pertussis toxin-sensitive guanine nucleotide-binding protein
    • Brass LF. Regulation of phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by pertussis toxin-sensitive guanine nucleotide-binding protein. J Biol Chem 1986;261:16833-47.
    • (1986) J Biol Chem , vol.261 , pp. 16833-16847
    • Brass, L.F.1
  • 41
    • 0030032791 scopus 로고    scopus 로고
    • Cellular consequences of thrombin-receptor activation
    • Grand RJA, Turnell AS, Grabham PW. Cellular consequences of thrombin-receptor activation. Biochem J 1996;313:353-68.
    • (1996) Biochem J , vol.313 , pp. 353-368
    • Grand, R.J.A.1    Turnell, A.S.2    Grabham, P.W.3
  • 42
    • 0023629566 scopus 로고
    • Growth inhibition by protein kinase C late in mitogenesis
    • Herang CL, Ives HE. Growth inhibition by protein kinase C late in mitogenesis. Nature 1987;329:849-50.
    • (1987) Nature , vol.329 , pp. 849-850
    • Herang, C.L.1    Ives, H.E.2
  • 44
    • 0028021308 scopus 로고
    • Inhibition of lysophosphatidate - And thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho
    • Jalink K, van Corven EJ, Hengeveld T, Morii N, Narumiya S, Moolenaar WH. Inhibition of lysophosphatidate - and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol 1994;126:801-10.
    • (1994) J Cell Biol , vol.126 , pp. 801-810
    • Jalink, K.1    Van Corven, E.J.2    Hengeveld, T.3    Morii, N.4    Narumiya, S.5    Moolenaar, W.H.6
  • 45
    • 33646310531 scopus 로고
    • Activation of Src family kinase activity by the G-protein coupled thrombin receptor in growth responsive fibroblasts
    • Chen Y. Activation of Src family kinase activity by the G-protein coupled thrombin receptor in growth responsive fibroblasts. J Biol Chem 1995;269:27327-77.
    • (1995) J Biol Chem , vol.269 , pp. 27327-27377
    • Chen, Y.1
  • 46
    • 0033532076 scopus 로고    scopus 로고
    • Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of G1-linked Ras/ mitogen-activated protein kinase pathway
    • Ellis CA, Malik AB, Gilchrist A, Hamm H, Sandoval R, Voyno-Yasenetskaya T, Tiruppathi C. Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of G1-linked Ras/ mitogen-activated protein kinase pathway. J Biol Chem 1999;274:13718-27.
    • (1999) J Biol Chem , vol.274 , pp. 13718-13727
    • Ellis, C.A.1    Malik, A.B.2    Gilchrist, A.3    Hamm, H.4    Sandoval, R.5    Voyno-Yasenetskaya, T.6    Tiruppathi, C.7
  • 47
    • 0025217864 scopus 로고
    • Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes
    • Oppenheim RW, Prevette D, Tytell M, Homma S. Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: evidence for the role of cell death genes. Dev Biol 1990;138:104-13.
    • (1990) Dev Biol , vol.138 , pp. 104-113
    • Oppenheim, R.W.1    Prevette, D.2    Tytell, M.3    Homma, S.4
  • 48
    • 0028286296 scopus 로고
    • Motoneurons deprived of trophic support in vitro require new gene expression to undergo programmed cell death
    • Milligan CE, Oppenheim RW, Schwartz LM. Motoneurons deprived of trophic support in vitro require new gene expression to undergo programmed cell death. J Neurobiol 1994;25:1005-16.
    • (1994) J Neurobiol , vol.25 , pp. 1005-1016
    • Milligan, C.E.1    Oppenheim, R.W.2    Schwartz, L.M.3
  • 51
    • 0031813736 scopus 로고    scopus 로고
    • Thrombin is a death signal that activates intracellular death protease pathways in motor neurons
    • Smirnova IV. Zhang SX, Citron BA, Arnold PM, Festoff BW. Thrombin is a death signal that activates intracellular death protease pathways in motor neurons. J Neurobiol 1998;36:64-80.
    • (1998) J Neurobiol , vol.36 , pp. 64-80
    • Smirnova, I.V.1    Zhang, S.X.2    Citron, B.A.3    Arnold, P.M.4    Festoff, B.W.5
  • 52
    • 0030984171 scopus 로고    scopus 로고
    • Inhibitors of trypsin-like serine proteases inhibit processing of the caspase nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support
    • Stefanis L, Troy CM, Haiquing Q, Lloyd A. Inhibitors of trypsin-like serine proteases inhibit processing of the caspase nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support. J Neurochem 1997;69:1425-37.
    • (1997) J Neurochem , vol.69 , pp. 1425-1437
    • Stefanis, L.1    Troy, C.M.2    Haiquing, Q.3    Lloyd, A.4
  • 53
    • 0033036882 scopus 로고    scopus 로고
    • Prevention of motoneuron degeneration induced by thrombin with different neurotrophic agents in highly enriched cultures
    • Turgeon VL, Houenou LJ. Prevention of motoneuron degeneration induced by thrombin with different neurotrophic agents in highly enriched cultures. J Comp Neurol 1999;38:571-80.
    • (1999) J Comp Neurol , vol.38 , pp. 571-580
    • Turgeon, V.L.1    Houenou, L.J.2
  • 54
    • 0029760923 scopus 로고    scopus 로고
    • Forging a path to cell death
    • Barinaga M. Forging a path to cell death. Science 1996;273:735-7.
    • (1996) Science , vol.273 , pp. 735-737
    • Barinaga, M.1
  • 55
    • 0030929149 scopus 로고    scopus 로고
    • Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: Control of neuronal morphology
    • Gebbink M, Kranenburg O, Poland M, van Horck, FPG, Houssa B, Moolenaar WH. Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology. J Cell Biol 1997;137:1603-13.
    • (1997) J Cell Biol , vol.137 , pp. 1603-1613
    • Gebbink, M.1    Kranenburg, O.2    Poland, M.3    Van Horck, F.P.G.4    Houssa, B.5    Moolenaar, W.H.6
  • 56
    • 0031042493 scopus 로고    scopus 로고
    • Rho, Rac, and Cdc42 GTPases regulate the organization of the actin cytoskeleton
    • Tapon N, Hall A. Rho, Rac, and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr Opin Cell Biol 1997;9:86-92.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 86-92
    • Tapon, N.1    Hall, A.2
  • 57
    • 0030866898 scopus 로고    scopus 로고
    • Role of a new Rho family member in cell migration and axon guidance in C. elegans
    • Zipkin LD, Kindt RM, Kenyon CJ. Role of a new Rho family member in cell migration and axon guidance in C. elegans. Cell 1997;90:883-94.
    • (1997) Cell , vol.90 , pp. 883-894
    • Zipkin, L.D.1    Kindt, R.M.2    Kenyon, C.J.3
  • 58
    • 0018932068 scopus 로고
    • Protease-nexin: A cellular component that links thrombin and plasminogen activator and mediates their binding to cells
    • Baker JB, Low DA, Simmer RL, Cunningham DD. Protease-nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells. Cell 1980;21:37-45.
    • (1980) Cell , vol.21 , pp. 37-45
    • Baker, J.B.1    Low, D.A.2    Simmer, R.L.3    Cunningham, D.D.4
  • 59
    • 0019797849 scopus 로고
    • Released protease-nexin regulates cellular binding, internalization and degradation of serine proteases
    • Low DA, Baker JB, Koone WC, Cunningham DD. Released protease-nexin regulates cellular binding, internalization and degradation of serine proteases. Proc Natl Acad Sci USA 1981;78:2340-4.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 2340-2344
    • Low, D.A.1    Baker, J.B.2    Koone, W.C.3    Cunningham, D.D.4
  • 61
    • 0023838532 scopus 로고
    • Immunochemical identification of the serine protease inhibitor alpha-1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease
    • Abraham CR, Slekow D, Potter H. Immunochemical identification of the serine protease inhibitor alpha-1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 1988;52:487-501.
    • (1988) Cell , vol.52 , pp. 487-501
    • Abraham, C.R.1    Slekow, D.2    Potter, H.3
  • 62
    • 0026706235 scopus 로고
    • The inhibition of thrombin and chymotrypsin by heparin-cofactor III
    • Struss D, Storck J, Zimmerman RE. The inhibition of thrombin and chymotrypsin by heparin-cofactor III. Thromb Res 1992;68:45-56.
    • (1992) Thromb Res , vol.68 , pp. 45-56
    • Struss, D.1    Storck, J.2    Zimmerman, R.E.3
  • 63
    • 0024336393 scopus 로고
    • The neurotrophic theory and naturally occurring motoneuron death
    • Oppenheim RW. The neurotrophic theory and naturally occurring motoneuron death. TINS 1989;12:252-5.
    • (1989) TINS , vol.12 , pp. 252-255
    • Oppenheim, R.W.1
  • 64
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim RW. Cell death during development of the nervous system. Ann Rev Neurosci 1991;14:453-501.
    • (1991) Ann Rev Neurosci , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 65
    • 0024270305 scopus 로고
    • The regulation of intramuscular nerve branching during normal development and following activity blockade
    • Dahm LM, Landmesser LT. The regulation of intramuscular nerve branching during normal development and following activity blockade. Dev Biol 1988;130:621-44.
    • (1988) Dev Biol , vol.130 , pp. 621-644
    • Dahm, L.M.1    Landmesser, L.T.2
  • 66
    • 0026490521 scopus 로고
    • The relationship of intramuscular nerve branching and synaptogenesis to motoneuron survival
    • Landmesser LT. The relationship of intramuscular nerve branching and synaptogenesis to motoneuron survival. J Neurobiol 1992;23:1131-9.
    • (1992) J Neurobiol , vol.23 , pp. 1131-1139
    • Landmesser, L.T.1
  • 67
    • 0023472748 scopus 로고
    • Chronic application of curare does not increase the level of motoneuron survival-promoting activity in limb muscle extracts during the naturally occurring motoneuron cell death period
    • Tanaka H. Chronic application of curare does not increase the level of motoneuron survival-promoting activity in limb muscle extracts during the naturally occurring motoneuron cell death period. Dev Biol 1987;124:347-57.
    • (1987) Dev Biol , vol.124 , pp. 347-357
    • Tanaka, H.1
  • 68
    • 0025720489 scopus 로고
    • Regulation of putative muscle-derived neurotrophic factors by muscle activity and innervation: In vivo and in vitro studies
    • Houenou LJ, McNanaman JL, Prevette D, Oppenheim RW. Regulation of putative muscle-derived neurotrophic factors by muscle activity and innervation: in vivo and in vitro studies. J Neurosci 1991;11:2829-37.
    • (1991) J Neurosci , vol.11 , pp. 2829-2837
    • Houenou, L.J.1    McNanaman, J.L.2    Prevette, D.3    Oppenheim, R.W.4
  • 69
    • 0027254498 scopus 로고
    • Biological studies of a putative avian muscle-derived neurotrophic factor that prevents naturally occurring motoneuron death in vivo
    • Oppenheim RW, Prevetter D, Haverkemp LJ, Houenou LJ, Yin QW, McNamaman J. Biological studies of a putative avian muscle-derived neurotrophic factor that prevents naturally occurring motoneuron death in vivo. J Neurobiol 1993;24:1065-79.
    • (1993) J Neurobiol , vol.24 , pp. 1065-1079
    • Oppenheim, R.W.1    Prevetter, D.2    Haverkemp, L.J.3    Houenou, L.J.4    Yin, Q.W.5    McNamaman, J.6
  • 70
    • 0023698784 scopus 로고
    • Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth
    • Monard D. Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth. TINS 1988;11:541-4.
    • (1988) TINS , vol.11 , pp. 541-544
    • Monard, D.1
  • 71
    • 0008119150 scopus 로고
    • Neuron-target cell interaction may involve protease-inhibitor interactions
    • 662Abst
    • Pittman RN. Neuron-target cell interaction may involve protease-inhibitor interactions. Soc Neurosci 1984;10:662 Abst.
    • (1984) Soc Neurosci , vol.10
    • Pittman, R.N.1
  • 72
    • 0019517250 scopus 로고
    • Development of the neuromuscular junction: Inductive interactions between cells
    • Dennis MJ. Development of the neuromuscular junction: inductive interactions between cells. Ann Rev Neurosci 1981;4:43-68.
    • (1981) Ann Rev Neurosci , vol.4 , pp. 43-68
    • Dennis, M.J.1
  • 73
    • 0023611560 scopus 로고
    • Plasminogen activators and inhibitors, roles in muscle and neuromuscular regeneration
    • Festoff BW, Hantai D. Plasminogen activators and inhibitors, roles in muscle and neuromuscular regeneration. Prog Brain Res 1987;71:423-431.
    • (1987) Prog Brain Res , vol.71 , pp. 423-431
    • Festoff, B.W.1    Hantai, D.2
  • 74
    • 78651127719 scopus 로고
    • Chemoaffinity in the orderly growth of nerve fiber patterns and connections
    • Sperry RW. Chemoaffinity in the orderly growth of nerve fiber patterns and connections. Proc Natl Acad Sci, USA 1963;50:703-704.
    • (1963) Proc Natl Acad Sci, USA , vol.50 , pp. 703-704
    • Sperry, R.W.1
  • 75
    • 0025076352 scopus 로고
    • Plasminogen activators and their inhibitors in the neuromuscular system I: Developmental regulation of plasminogen activator isoforms during in vitro myogenesis in two cell lines
    • Festoff BW, Rao JS, Maben C, Hantai D. Plasminogen activators and their inhibitors in the neuromuscular system I: Developmental regulation of plasminogen activator isoforms during in vitro myogenesis in two cell lines. J Cell Physiol 1990;144:262-271.
    • (1990) J Cell Physiol , vol.144 , pp. 262-271
    • Festoff, B.W.1    Rao, J.S.2    Maben, C.3    Hantai, D.4
  • 77
    • 0022203159 scopus 로고
    • Tranglutaminase activity in the rat brain: Characterization, distribution, and changes with age
    • Gilad GM, Varon LE. Tranglutaminase activity in the rat brain: characterization, distribution, and changes with age. J Neurochem 1985;45:1522-1526.
    • (1985) J Neurochem , vol.45 , pp. 1522-1526
    • Gilad, G.M.1    Varon, L.E.2
  • 78
    • 6844241936 scopus 로고    scopus 로고
    • Effects of thrombin and protease nexin-1 on peripheral nerve regeneration
    • Lee P, Spector JG, Derby A, Roufa DG. Effects of thrombin and protease nexin-1 on peripheral nerve regeneration. Ann Otol Rhinol Laryngol 1998;107:61-9.
    • (1998) Ann Otol Rhinol Laryngol , vol.107 , pp. 61-69
    • Lee, P.1    Spector, J.G.2    Derby, A.3    Roufa, D.G.4
  • 80
    • 0026656903 scopus 로고
    • Biphasic increase in c-jun mRNA is required for induction of AP-1-mediator gene transcription: Differentiation effects of muscarinic and thrombin receptor activation
    • Trejo J, Chambord JC, Karin M, Brown JH. Biphasic increase in c-jun mRNA is required for induction of AP-1-mediator gene transcription: differentiation effects of muscarinic and thrombin receptor activation. Mol Cell Biol 1992;12:4742-50.
    • (1992) Mol Cell Biol , vol.12 , pp. 4742-4750
    • Trejo, J.1    Chambord, J.C.2    Karin, M.3    Brown, J.H.4
  • 82
    • 0029914487 scopus 로고    scopus 로고
    • Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by β-amyloid in vitro
    • Pike CJ, Vaughan PJ, Cunningham DD, Cotman CW. Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by β-amyloid in vitro. J Neurochem 1996;66:1374-82.
    • (1996) J Neurochem , vol.66 , pp. 1374-1382
    • Pike, C.J.1    Vaughan, P.J.2    Cunningham, D.D.3    Cotman, C.W.4
  • 83
    • 0002906957 scopus 로고
    • Platelet membrane proteins: Composition and receptor functions
    • Gordon J, editor. Amsterdam: Elsevier
    • Berndt M, Phillips D. Platelet membrane proteins: composition and receptor functions. In: Gordon J, editor. Platelets in biology and pathology. Amsterdam: Elsevier; 1981. p. 43-7.
    • (1981) Platelets in Biology and Pathology , pp. 43-47
    • Berndt, M.1    Phillips, D.2
  • 84
    • 0021091174 scopus 로고
    • Rector-mediated chemotactic response of a macrophage cell line (J774) to thrombin
    • Bar-Shavit R, Kahn A, Fenton JWII, Wilner GD. Rector-mediated chemotactic response of a macrophage cell line (J774) to thrombin. Lab Invest 1983;49:702-7.
    • (1983) Lab Invest , vol.49 , pp. 702-707
    • Bar-Shavit, R.1    Kahn, A.2    Fenton, J.W.I.I.3    Wilner, G.D.4
  • 85
    • 0019305915 scopus 로고
    • Thrombin active site regions required for fibroblast receptor binding and initiation of cell division
    • Glenn KC, Carney DH, Fenton JW, Cunningham DD. Thrombin active site regions required for fibroblast receptor binding and initiation of cell division. J Biol Chem 1980;225:6609-16.
    • (1980) J Biol Chem , vol.225 , pp. 6609-6616
    • Glenn, K.C.1    Carney, D.H.2    Fenton, J.W.3    Cunningham, D.D.4
  • 86
    • 0029134929 scopus 로고
    • Opposing actions of thrombin and protease nexin-1 on amyloid β-peptide toxicity and on accumulation of peroxides and calcium in hippocampal neurons
    • Smith-Swintowsky VL, Zimmer S, Fenton JWII, Mattson MP. Opposing actions of thrombin and protease nexin-1 on amyloid β-peptide toxicity and on accumulation of peroxides and calcium in hippocampal neurons. J Neurochem 1995;65:1415-8.
    • (1995) J Neurochem , vol.65 , pp. 1415-1418
    • Smith-Swintowsky, V.L.1    Zimmer, S.2    Fenton, J.W.I.I.3    Mattson, M.P.4
  • 87
    • 0025500410 scopus 로고
    • Protease nexin-1. Localization in the human brain suggests a protective role against extravasated serine proteases
    • Choi BH, Suzuki M, Kim T, Wagner SL, Cunningham DD. Protease nexin-1. Localization in the human brain suggests a protective role against extravasated serine proteases. Amer J Pathol 1990;137:741-7.
    • (1990) Amer J Pathol , vol.137 , pp. 741-747
    • Choi, B.H.1    Suzuki, M.2    Kim, T.3    Wagner, S.L.4    Cunningham, D.D.5
  • 89
    • 0022924095 scopus 로고
    • Thrombin-induced alteration sin endothelial permeability
    • Malik AB, Lo SK, Bizios R. Thrombin-induced alteration sin endothelial permeability. Ann NY Acad Sci 1986;485:293-309.
    • (1986) Ann NY Acad Sci , vol.485 , pp. 293-309
    • Malik, A.B.1    Lo, S.K.2    Bizios, R.3
  • 91
    • 0026915263 scopus 로고
    • The blood brain barrier and cerebral microcirculation in Alzheimer's disease
    • Kalarai RN. The blood brain barrier and cerebral microcirculation in Alzheimer's disease. Cerebrovas Brain Metab Rev 1992;4:226-60.
    • (1992) Cerebrovas Brain Metab Rev , vol.4 , pp. 226-260
    • Kalarai, R.N.1
  • 92
    • 0026763045 scopus 로고
    • The prolonged presence of glial-derived nexin, a serine protease inhibitor, in the hippocampus after transient global ischemia
    • Hoffman MC, Nilson C, Scotti A, Reinhard E, Monard D. The prolonged presence of glial-derived nexin, a serine protease inhibitor, in the hippocampus after transient global ischemia. Neurosci 1992;49:397-408.
    • (1992) Neurosci , vol.49 , pp. 397-408
    • Hoffman, M.C.1    Nilson, C.2    Scotti, A.3    Reinhard, E.4    Monard, D.5
  • 93
    • 0027412354 scopus 로고
    • The glia-derived protease nexin-1 persists for over one year in rat brain area selectively lesioned by transient global ischemia
    • Nitsch C, Scotti AL, Monard D, Heim C, Sontag KH. The glia-derived protease nexin-1 persists for over one year in rat brain area selectively lesioned by transient global ischemia. Eur J Neurosci 1993;5:292-7.
    • (1993) Eur J Neurosci , vol.5 , pp. 292-297
    • Nitsch, C.1    Scotti, A.L.2    Monard, D.3    Heim, C.4    Sontag, K.H.5
  • 95
    • 0027468772 scopus 로고
    • Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors
    • Vaughan DJ, Cunningham DD. Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors. J Biol Chem 1993;268:3720-7.
    • (1993) J Biol Chem , vol.268 , pp. 3720-3727
    • Vaughan, D.J.1    Cunningham, D.D.2
  • 96
    • 0022999868 scopus 로고
    • Effects of proteases and their inhibitors in neurite outgrowth from neonatal mouse sensory ganglia in culture
    • Hawkins RL, Seeds NW. Effects of proteases and their inhibitors in neurite outgrowth from neonatal mouse sensory ganglia in culture. Brain Res 1986;398:63-70.
    • (1986) Brain Res , vol.398 , pp. 63-70
    • Hawkins, R.L.1    Seeds, N.W.2
  • 97
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • Glenner GC, Wong CW. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 1984;120:885-890.
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 885-890
    • Glenner, G.C.1    Wong, C.W.2
  • 100
    • 0027407570 scopus 로고
    • Generation of β-amyloid in the secretory pathway in neuronal and non neuronal cells
    • Busciglio J, Gabuzda DH, Matsudaira P, Yanker BA. Generation of β-amyloid in the secretory pathway in neuronal and non neuronal cells. Proc Natl Acad Sci, USA 1993;90:2092-6.
    • (1993) Proc Natl Acad Sci, USA , vol.90 , pp. 2092-2096
    • Busciglio, J.1    Gabuzda, D.H.2    Matsudaira, P.3    Yanker, B.A.4
  • 101
    • 0025753852 scopus 로고
    • The molecular pathology of Alzheimer's disease
    • Selkoe DJ. The molecular pathology of Alzheimer's disease. Neuron 1991;6:487-98.
    • (1991) Neuron , vol.6 , pp. 487-498
    • Selkoe, D.J.1
  • 102
    • 0026772783 scopus 로고
    • Proteolytic processing of amyloid beta protein precursor (APP) by thrombin
    • Igarashi K, Murai H, Asaka J. Proteolytic processing of amyloid beta protein precursor (APP) by thrombin. Biochem Biophys Res Commun 1992;185:1000-1004.
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 1000-1004
    • Igarashi, K.1    Murai, H.2    Asaka, J.3
  • 105
    • 0026454599 scopus 로고
    • Thrombin accumulation in brains of patients with Alzheimer's disease
    • Akiyama H, Ikeda K, Kondo H, McGeer PI. Thrombin accumulation in brains of patients with Alzheimer's disease. Neurosci Lett 1992;146:152-154.
    • (1992) Neurosci Lett , vol.146 , pp. 152-154
    • Akiyama, H.1    Ikeda, K.2    Kondo, H.3    McGeer, P.I.4
  • 108
    • 0024363137 scopus 로고
    • Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage
    • Siman R, Noszek JC, Kegerise C. Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage. J Neurosci 1989;9:1579-90.
    • (1989) J Neurosci , vol.9 , pp. 1579-1590
    • Siman, R.1    Noszek, J.C.2    Kegerise, C.3
  • 109
    • 0025071270 scopus 로고
    • Differential vulnerability of microtubule components in cerebral ischemia
    • Yanagihara Y, Brengman JM, Mushynski WE. Differential vulnerability of microtubule components in cerebral ischemia. Acta Neuropath 1990;80:499-505.
    • (1990) Acta Neuropath , vol.80 , pp. 499-505
    • Yanagihara, Y.1    Brengman, J.M.2    Mushynski, W.E.3
  • 110
    • 0026570528 scopus 로고
    • Beta-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydell RE. Beta-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992;12:376-89.
    • (1992) J Neurosci , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydell, R.E.6
  • 113
    • 0023875264 scopus 로고
    • Neurite outgrowth in individual neurons of a neuronal population is differentially regulated by calcium and cyclic AMP
    • Mattson MP, Taylor-Hunter A, Kater SB. Neurite outgrowth in individual neurons of a neuronal population is differentially regulated by calcium and cyclic AMP. J Neurosci 1988;8:1704-11.
    • (1988) J Neurosci , vol.8 , pp. 1704-1711
    • Mattson, M.P.1    Taylor-Hunter, A.2    Kater, S.B.3
  • 114
    • 0024345451 scopus 로고
    • Fibroblast growth factor and glutamate: Opposing roles in the generation and degeneration of hippocampal neuroarchitecture
    • Mattson MP, Murrain M, Guthrie, Kater SB. Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture. J Neurosci 1989;9:3728-40.
    • (1989) J Neurosci , vol.9 , pp. 3728-3740
    • Mattson, M.P.1    Murrain, M.2    Guthrie3    Kater, S.B.4
  • 115
    • 0028175579 scopus 로고
    • Secreted forms of β-amyloid precursor protein modulate dendritic outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons
    • Mattson MP. Secreted forms of β-amyloid precursor protein modulate dendritic outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons. J Neurobiol 1993;25:439-50.
    • (1993) J Neurobiol , vol.25 , pp. 439-450
    • Mattson, M.P.1
  • 116
    • 0021811514 scopus 로고
    • Calcium-dependent transglutaminase of rat sympathetic ganglion in development and after nerve injury
    • Gilad GM, Varon LE, Gilad VH. Calcium-dependent transglutaminase of rat sympathetic ganglion in development and after nerve injury. J Neurochem 1985;44:1385-1390.
    • (1985) J Neurochem , vol.44 , pp. 1385-1390
    • Gilad, G.M.1    Varon, L.E.2    Gilad, V.H.3
  • 117
    • 0029012029 scopus 로고
    • Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults
    • Vaughan PJ, Pike CJ, Cotman CW, Cunningham DD. Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J Neurosci 1995;157:5389-5401.
    • (1995) J Neurosci , vol.157 , pp. 5389-5401
    • Vaughan, P.J.1    Pike, C.J.2    Cotman, C.W.3    Cunningham, D.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.