메뉴 건너뛰기




Volumn 9, Issue 1-2, 1999, Pages 42-48

Proteolytically activated receptor-3: A member of an emerging gene family of protease receptors expressed on vascular endothelial cells and platelets

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEINASE ACTIVATED RECEPTOR 3; SERINE PROTEINASE; UNCLASSIFIED DRUG;

EID: 0033001930     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(99)00005-5     Document Type: Article
Times cited : (34)

References (39)
  • 2
    • 0027155450 scopus 로고
    • The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation
    • Bahou W., Coller B., Potter C., Norton K., Kutok J., Goligorsky M. The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation. J Clin Invest. 91:1993;1405-1413.
    • (1993) J Clin Invest , vol.91 , pp. 1405-1413
    • Bahou, W.1    Coller, B.2    Potter, C.3    Norton, K.4    Kutok, J.5    Goligorsky, M.6
  • 3
    • 0027983873 scopus 로고
    • Identification of a thrombin receptor sequence specifying activation-dependent responses
    • Bahou W., Kutok J., Wong A., Potter C., Coller B. Identification of a thrombin receptor sequence specifying activation-dependent responses. Blood. 84:1994;4195-4202.
    • (1994) Blood , vol.84 , pp. 4195-4202
    • Bahou, W.1    Kutok, J.2    Wong, A.3    Potter, C.4    Coller, B.5
  • 4
    • 0027258993 scopus 로고
    • Chromosomal assignment of the human thrombin receptor gene: Localization to region q13 of chromosome 5
    • Bahou W.F., Nierman W.C., Durkin A.S., Potter C.L., Demetrick D.J. Chromosomal assignment of the human thrombin receptor gene. localization to region q13 of chromosome 5 Blood. 82:1993;1532-1537.
    • (1993) Blood , vol.82 , pp. 1532-1537
    • Bahou, W.F.1    Nierman, W.C.2    Durkin, A.S.3    Potter, C.L.4    Demetrick, D.J.5
  • 5
    • 0030478946 scopus 로고    scopus 로고
    • Molecular characterization of proteolytically activated receptors: Insights from the thrombin receptor and proteinase activated receptor-2 (PAR-2) genes
    • Bahou W.F., Schmidt V.A. Molecular characterization of proteolytically activated receptors. insights from the thrombin receptor and proteinase activated receptor-2 (PAR-2) genes Platelets. 7:1996;253-260.
    • (1996) Platelets , vol.7 , pp. 253-260
    • Bahou, W.F.1    Schmidt, V.A.2
  • 6
    • 0026631543 scopus 로고
    • Structure and function of the human platelet thrombin receptor. Studies using monoclonal antibodies directed against a defined domain within the receptor N terminus
    • Brass L., Vassallo R., Belmonte E., Ahuja M., Cichowski K., Hoxie J. Structure and function of the human platelet thrombin receptor. Studies using monoclonal antibodies directed against a defined domain within the receptor N terminus. J Biol Chem. 267:1992;13,795-13,798.
    • (1992) J Biol Chem , vol.267 , pp. 13
    • Brass, L.1    Vassallo, R.2    Belmonte, E.3    Ahuja, M.4    Cichowski, K.5    Hoxie, J.6
  • 7
    • 0029847188 scopus 로고    scopus 로고
    • 2+ oscillations in madin-darby canine kidney cells only when proteolytically active
    • 2+ oscillations in madin-darby canine kidney cells only when proteolytically active. J Biol Chem. 271:1996;29,034-29,042.
    • (1996) J Biol Chem , vol.271 , pp. 29
    • Camerer, E.1    Rottingen, J.2    Iversen, J.3    Prydz, H.4
  • 8
    • 0028946244 scopus 로고
    • Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences
    • Chaikoff E.L., Caban R., Yan C., Runge M.S. Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences. J Biol Chem. 270:1995;7431-7436.
    • (1995) J Biol Chem , vol.270 , pp. 7431-7436
    • Chaikoff, E.L.1    Caban, R.2    Yan, C.3    Runge, M.S.4
  • 9
    • 0027529258 scopus 로고
    • Human plasmin induces a receptor-mediated arachidonate release coupled with G proteins in endothelial cells
    • Chang W.C., Shi G.Y., Chow Y.H.et al. Human plasmin induces a receptor-mediated arachidonate release coupled with G proteins in endothelial cells. Am J Physiol. 264:1993;C271-C281.
    • (1993) Am J Physiol , vol.264
    • Chang, W.C.1    Shi, G.Y.2    Chow, Y.H.3
  • 10
    • 0030008312 scopus 로고    scopus 로고
    • Role of the thrombin receptor in development and evidence for a second receptor
    • Connolly A.J., Ishihara H., Kahn M.L., Farese R.V., Coughlin S.R. Role of the thrombin receptor in development and evidence for a second receptor. Nature. 38:1996;516-519.
    • (1996) Nature , vol.38 , pp. 516-519
    • Connolly, A.J.1    Ishihara, H.2    Kahn, M.L.3    Farese, R.V.4    Coughlin, S.R.5
  • 11
    • 0014191175 scopus 로고
    • Actions of thrombin and other coagulant and proteolytic enzymes on platelets
    • Davey M.E., Luscher S.R. Actions of thrombin and other coagulant and proteolytic enzymes on platelets. Nature. 216:1967;857-858.
    • (1967) Nature , vol.216 , pp. 857-858
    • Davey, M.E.1    Luscher, S.R.2
  • 12
    • 0028283850 scopus 로고
    • Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface
    • Gerstzen R.E., Chen J., Ishii M.et al. Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface. Nature. 368:1994;648-651.
    • (1994) Nature , vol.368 , pp. 648-651
    • Gerstzen, R.E.1    Chen, J.2    Ishii, M.3
  • 13
    • 0030030210 scopus 로고    scopus 로고
    • Protease-mediated signalling-new paradigms for cell regulation and drug development
    • Hollenberg M.D. Protease-mediated signalling-new paradigms for cell regulation and drug development. Trends Pharmacol Sci. 17:1996;3-6.
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 3-6
    • Hollenberg, M.D.1
  • 15
    • 0030979972 scopus 로고    scopus 로고
    • Protease-activated receptor 3 is a second thrombin receptor in humans
    • Ishihara H., Connolly A.J., Zeng D.et al. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature. 386:1997;502-506.
    • (1997) Nature , vol.386 , pp. 502-506
    • Ishihara, H.1    Connolly, A.J.2    Zeng, D.3
  • 16
    • 0032101592 scopus 로고    scopus 로고
    • Antibodies to protease-activated receptor 3 inhibit activation of mouse platelets by thrombin
    • Ishihara H., Zeng D., Connolly A.J., Tam C., Coughlin S.R. Antibodies to protease-activated receptor 3 inhibit activation of mouse platelets by thrombin. Blood. 91:1998;4152-4157.
    • (1998) Blood , vol.91 , pp. 4152-4157
    • Ishihara, H.1    Zeng, D.2    Connolly, A.J.3    Tam, C.4    Coughlin, S.R.5
  • 17
    • 0032514474 scopus 로고    scopus 로고
    • A dual thrombin receptor system for platelet activation
    • a
    • Kahn M.L., Zhang Y., Huang W.et al. A dual thrombin receptor system for platelet activation. Nature. 394:1998;690-694. a.
    • (1998) Nature , vol.394 , pp. 690-694
    • Kahn, M.L.1    Zhang, Y.2    Huang, W.3
  • 18
    • 0032483456 scopus 로고    scopus 로고
    • Gene and locus structure and chromosomal localization of the protease-activated receptor gene family
    • b
    • Kahn M.L., Hammes S.R., Botka C., Coughlin S.R. Gene and locus structure and chromosomal localization of the protease-activated receptor gene family. J Biol Chem. 273:1998;23,290-23,296. b.
    • (1998) J Biol Chem , vol.273 , pp. 23
    • Kahn, M.L.1    Hammes, S.R.2    Botka, C.3    Coughlin, S.R.4
  • 19
    • 0027733860 scopus 로고
    • Degranulation of human platelets by the thrombin receptor peptide SFLLRN: Comparison with degranulation by thrombin
    • Kinlough-Rathbone R.L., Perry D.W., Guccione M.A., Rand M.L., Packham M.A. Degranulation of human platelets by the thrombin receptor peptide SFLLRN. comparison with degranulation by thrombin Thromb Haemost. 70:1993;1019-1023.
    • (1993) Thromb Haemost , vol.70 , pp. 1019-1023
    • Kinlough-Rathbone, R.L.1    Perry, D.W.2    Guccione, M.A.3    Rand, M.L.4    Packham, M.A.5
  • 20
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
    • Liotta L.A., Steeg P.S., Stetler-Stevenson W.G. Cancer metastasis and angiogenesis. an imbalance of positive and negative regulation Cell. 64:1991;327-336.
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.A.1    Steeg, P.S.2    Stetler-Stevenson, W.G.3
  • 21
    • 0030783689 scopus 로고    scopus 로고
    • Mitogenic responses mediated through the proteinase activated receptor-2 are induced by mast cell α- And β- tryptases
    • Mirza H., Schmidt V., Derian C., Jesty J., Bahou W. Mitogenic responses mediated through the proteinase activated receptor-2 are induced by mast cell α- and β- tryptases. Blood. 90:1997;3914-3922.
    • (1997) Blood , vol.90 , pp. 3914-3922
    • Mirza, H.1    Schmidt, V.2    Derian, C.3    Jesty, J.4    Bahou, W.5
  • 22
    • 0030003829 scopus 로고    scopus 로고
    • The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. Molecular characterization and evidence for functional coupling to the thrombin receptor
    • Mirza H., Yatsula V., Bahou W.F. The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. Molecular characterization and evidence for functional coupling to the thrombin receptor. J Clin Invest. 97:1996;1705-1714.
    • (1996) J Clin Invest , vol.97 , pp. 1705-1714
    • Mirza, H.1    Yatsula, V.2    Bahou, W.F.3
  • 23
    • 0026051572 scopus 로고
    • A 14 amino acid peptide derived from the amino terminus of the cleaved thrombin receptor elevates intracellular calcium and stimulates prostacyclin production in human endothelial cells
    • Ngaiza J., Jaffe E. A 14 amino acid peptide derived from the amino terminus of the cleaved thrombin receptor elevates intracellular calcium and stimulates prostacyclin production in human endothelial cells. Biochem Biophys Res Comm. 179:1991;1656-1661.
    • (1991) Biochem Biophys Res Comm , vol.179 , pp. 1656-1661
    • Ngaiza, J.1    Jaffe, E.2
  • 24
    • 0027488033 scopus 로고
    • Immunologic analysis of the cloned platelet thrombin receptor activation mechanism: Evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment
    • Norton K.J., Scarborough R.M., Kutok J.L., Escobedo M.A., Nannizzi L., Coller B.S. Immunologic analysis of the cloned platelet thrombin receptor activation mechanism. evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment Blood. 82:1993;2125-2136.
    • (1993) Blood , vol.82 , pp. 2125-2136
    • Norton, K.J.1    Scarborough, R.M.2    Kutok, J.L.3    Escobedo, M.A.4    Nannizzi, L.5    Coller, B.S.6
  • 25
    • 0029113121 scopus 로고
    • Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
    • Nystedt S., Emilsson K., Larsson A.K., Strombeck B., Sundelin J. Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur J Biochem. 232:1995;84-89.
    • (1995) Eur J Biochem , vol.232 , pp. 84-89
    • Nystedt, S.1    Emilsson, K.2    Larsson, A.K.3    Strombeck, B.4    Sundelin, J.5
  • 26
    • 15844401726 scopus 로고    scopus 로고
    • The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor
    • Nystedt S., Ramakrishnan S., Sundelin J. The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor. J Biol Chem. 271:1996;14,910-14,915.
    • (1996) J Biol Chem , vol.271 , pp. 14
    • Nystedt, S.1    Ramakrishnan, S.2    Sundelin, J.3
  • 27
    • 0030968521 scopus 로고    scopus 로고
    • Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G and proteinase 3: Evidence for distinct cleavage sites within the amino terminal domain of the thrombin receptor
    • Renesto P., Si-Tahar M., Moniatte M.et al. Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G and proteinase 3. evidence for distinct cleavage sites within the amino terminal domain of the thrombin receptor Blood. 89:1997;1944-1953.
    • (1997) Blood , vol.89 , pp. 1944-1953
    • Renesto, P.1    Si-Tahar, M.2    Moniatte, M.3
  • 28
    • 0030883750 scopus 로고    scopus 로고
    • Cloning of PAR3 cDNA from human platelets, and human erythroleukemic and human promo-nocytic cell lines. (Letter to the editor)
    • Scase T.J., Heath M.F., Evans R.J. Cloning of PAR3 cDNA from human platelets, and human erythroleukemic and human promo-nocytic cell lines. (Letter to the editor). Blood. 90:1997;2113-2114.
    • (1997) Blood , vol.90 , pp. 2113-2114
    • Scase, T.J.1    Heath, M.F.2    Evans, R.J.3
  • 30
    • 0029919173 scopus 로고    scopus 로고
    • Genomic cloning and characterization of the human thrombin receptor gene: Evidence for a novel gene family that includes PAR-2
    • Schmidt V., Vitale E., Bahou W. Genomic cloning and characterization of the human thrombin receptor gene. evidence for a novel gene family that includes PAR-2 J Biol Chem. 271:1996;9307-9312.
    • (1996) J Biol Chem , vol.271 , pp. 9307-9312
    • Schmidt, V.1    Vitale, E.2    Bahou, W.3
  • 31
    • 0030946582 scopus 로고    scopus 로고
    • The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13
    • Schmidt V.A., Nierman W.C., Feldblyum T.V., Maglott D.R., Bahou W.F. The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13. Br J Haematol. 97:1997;523-529.
    • (1997) Br J Haematol , vol.97 , pp. 523-529
    • Schmidt, V.A.1    Nierman, W.C.2    Feldblyum, T.V.3    Maglott, D.R.4    Bahou, W.F.5
  • 32
    • 0032510949 scopus 로고    scopus 로고
    • The human proteinase-activated receptor-3 (PAR-3) gene
    • Schmidt V.A., Nierman W.C., Maglott D.R.et al. The human proteinase-activated receptor-3 (PAR-3) gene. J Biol Chem. 273:1998;15,061-15,068.
    • (1998) J Biol Chem , vol.273 , pp. 15
    • Schmidt, V.A.1    Nierman, W.C.2    Maglott, D.R.3
  • 33
    • 0022924087 scopus 로고
    • Thrombin cellular interactions
    • Shuman M.A. Thrombin cellular interactions. Ann NY Acad Sci. 485:1988;228-239.
    • (1988) Ann NY Acad Sci , vol.485 , pp. 228-239
    • Shuman, M.A.1
  • 34
    • 0028059276 scopus 로고
    • Granzyme A released upon stimulation of cytoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes
    • Suidan H.S., Bouvier J., Schaerer E., Stone S.R., Monard D., Tschopp J. Granzyme A released upon stimulation of cytoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes. Proc Natl Acad Sci USA. 91:1994;8112-8116.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8112-8116
    • Suidan, H.S.1    Bouvier, J.2    Schaerer, E.3    Stone, S.R.4    Monard, D.5    Tschopp, J.6
  • 35
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice
    • Thompson J.D., Higgins D.G., Gibson T.J. CLUSTAL W. improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice Nucl Acids Res. 22:1994;4673-4680.
    • (1994) Nucl Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 36
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu T., Hung D., Wheaton V., Coughlin S. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 64:1991;1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.1    Hung, D.2    Wheaton, V.3    Coughlin, S.4
  • 37
    • 0026072517 scopus 로고
    • Domains specifying thrombin-receptor interaction
    • Vu T., Wheaton V., Hung D., Charo I., Coughlin S. Domains specifying thrombin-receptor interaction. Nature. 353:1991;674-677.
    • (1991) Nature , vol.353 , pp. 674-677
    • Vu, T.1    Wheaton, V.2    Hung, D.3    Charo, I.4    Coughlin, S.5
  • 38
    • 0032499696 scopus 로고    scopus 로고
    • Cloning and characterization of human protease-activated receptor 4
    • Xu W., Andersen H., Whitmore T.E.et al. Cloning and characterization of human protease-activated receptor 4. Proc Natl Acad Sci USA. 95:1998;6642-6646.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6642-6646
    • Xu, W.1    Andersen, H.2    Whitmore, T.E.3
  • 39
    • 0026802136 scopus 로고
    • Molecular cloning of the rat vascular smooth muscle thrombin receptor. Evidence for in vivo regulation by basic fibroblast growth factor
    • Zhong C., Hayzer D., Corson M., Runge M. Molecular cloning of the rat vascular smooth muscle thrombin receptor. Evidence for in vivo regulation by basic fibroblast growth factor. J Biol Chem. 267:1992;16,975-16,979.
    • (1992) J Biol Chem , vol.267 , pp. 16
    • Zhong, C.1    Hayzer, D.2    Corson, M.3    Runge, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.