-
1
-
-
0029112841
-
Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface
-
Esmon CT. Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface. FASEB J 1995; 9: 946-55.
-
(1995)
FASEB J
, vol.9
, pp. 946-955
-
-
Esmon, C.T.1
-
2
-
-
0029014036
-
An allosteric switch controls the procoagulant and anticoagulant activities of thrombin
-
Dang QD, Vindigni A, Di Cera E. An allosteric switch controls the procoagulant and anticoagulant activities of thrombin. Proc Natl Acad Sci USA 1995; 92: 5977-5981.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5977-5981
-
-
Dang, Q.D.1
Vindigni, A.2
Di Cera, E.3
-
3
-
-
0026476381
-
Thrombin is a Na(+)-activated enzyme
-
Wells CM, Di Cera E. Thrombin is a Na(+)-activated enzyme. Biochemistry 1992; 31: 11721-11730.
-
(1992)
Biochemistry
, vol.31
, pp. 11721-11730
-
-
Wells, C.M.1
Di Cera, E.2
-
5
-
-
0029785840
-
+-induced allosteric regulation of catalytic activity in serine proteases
-
+-induced allosteric regulation of catalytic activity in serine proteases. Proc Natl Acad Sci USA 1996; 93: 10653-10656.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10653-10656
-
-
Dang, Q.D.1
Di Cera, E.2
-
6
-
-
0025951949
-
Single amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin
-
Wu Q, Sheehan JP, Tsiang M, Lentz SR, Birktoft JJ, Sadler JE. Single amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin. Proc Natl Acad Sci USA 1991; 88: 6775-6779.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 6775-6779
-
-
Wu, Q.1
Sheehan, J.P.2
Tsiang, M.3
Lentz, S.R.4
Birktoft, J.J.5
Sadler, J.E.6
-
7
-
-
0029017360
-
Functional mapping of the surface residues of thrombin
-
Tsiang M, Jain AK, Dunn KE, Rojas ME, Leung LLK, Gibbs CS. Functional mapping of the surface residues of thrombin. J Biol Chem 1995; 270: 16854-16863.
-
(1995)
J Biol Chem
, vol.270
, pp. 16854-16863
-
-
Tsiang, M.1
Jain, A.K.2
Dunn, K.E.3
Rojas, M.E.4
Leung, L.L.K.5
Gibbs, C.S.6
-
10
-
-
0027972583
-
-
Gan ZR, Li Y, Chen Z, Lewis SD, Shafer JA. J Biol Chem 1994; 269: 1301-1305.
-
(1994)
J Biol Chem
, vol.269
, pp. 1301-1305
-
-
Gan, Z.R.1
Li, Y.2
Chen, Z.3
Lewis, S.D.4
Shafer, J.A.5
-
11
-
-
0028811156
-
Conversion of thrombin into an anticoagulant by protein engineering
-
Gibbs CS, Coutre SE, Tsiang M, Li WX, Jain AK, Dunn KE, Law VS, Mao CT, Matsumura SY, Mejza SJ, Paborsky LR, Leung LLK. Conversion of thrombin into an anticoagulant by protein engineering. Nature 1995; 378: 413-416.
-
(1995)
Nature
, vol.378
, pp. 413-416
-
-
Gibbs, C.S.1
Coutre, S.E.2
Tsiang, M.3
Li, W.X.4
Jain, A.K.5
Dunn, K.E.6
Law, V.S.7
Mao, C.T.8
Matsumura, S.Y.9
Mejza, S.J.10
Paborsky, L.R.11
Leung, L.L.K.12
-
12
-
-
12644264319
-
Protein engineering thrombin for optimal specificity and potency of anticoagulant activity in vivo
-
Tsiang M, Paborsky LR, Li WX, Jain AK, Mao CT, Dunn KE, Lee DW, Matsumura SY, Matteucci M, Coutre SE, Leung LLK, Gibbs CS. Protein engineering thrombin for optimal specificity and potency of anticoagulant activity in vivo. Biochemistry 1996; 35: 16449-16457.
-
(1996)
Biochemistry
, vol.35
, pp. 16449-16457
-
-
Tsiang, M.1
Paborsky, L.R.2
Li, W.X.3
Jain, A.K.4
Mao, C.T.5
Dunn, K.E.6
Lee, D.W.7
Matsumura, S.Y.8
Matteucci, M.9
Coutre, S.E.10
Leung, L.L.K.11
Gibbs, C.S.12
-
13
-
-
0023199871
-
Ligands which effect human protein C activation by thrombin
-
Musci G, Berliner LJ. Ligands which effect human protein C activation by thrombin. J Biol Chem 1987; 262:13889-13891
-
(1987)
J Biol Chem
, vol.262
, pp. 13889-13891
-
-
Musci, G.1
Berliner, L.J.2
-
14
-
-
0029817671
-
Enhanced protein C activtion and inhibition of fibrinogen cleavage by a thrombin modulator
-
Berg DT, Wiley MR, Grinnell BW. Enhanced protein C activtion and inhibition of fibrinogen cleavage by a thrombin modulator. Science 1996; 273: 1389-1391.
-
(1996)
Science
, vol.273
, pp. 1389-1391
-
-
Berg, D.T.1
Wiley, M.R.2
Grinnell, B.W.3
-
15
-
-
0028328512
-
Recombinant soluble human thrombomodulin: A randomized, blinded assessment of prevention of venous thrombosis and effects on hemostatic parameters in a rat model
-
Solis MM, Vitti M, Cook J, Young D, Glaser C, Light D, Morser J, Wydro R, Yu S, Fink L, et al. Recombinant soluble human thrombomodulin: a randomized, blinded assessment of prevention of venous thrombosis and effects on hemostatic parameters in a rat model. Thromb Res 1994; 73: 385-394
-
(1994)
Thromb Res
, vol.73
, pp. 385-394
-
-
Solis, M.M.1
Vitti, M.2
Cook, J.3
Young, D.4
Glaser, C.5
Light, D.6
Morser, J.7
Wydro, R.8
Yu, S.9
Fink, L.10
-
16
-
-
0029148565
-
Antithrombotic action of endogenous porcine protein C activated with a latent porcine thrombin preparation
-
McBane RD, Wysokinski WE, Chesebro JH, Owen WG. Antithrombotic action of endogenous porcine protein C activated with a latent porcine thrombin preparation. Thromb. Haemostasis 1995; 74: 879-885
-
(1995)
Thromb. Haemostasis
, vol.74
, pp. 879-885
-
-
McBane, R.D.1
Wysokinski, W.E.2
Chesebro, J.H.3
Owen, W.G.4
|