The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells: Comparison with the thrombin receptor

Journal of Biological Chemistry

Volumn 271, Issue 25, 1996, Pages 14910-14915

  Nystedt, Sverker ^a   Ramakrishnan, Vanitha ^b   Sundelin, Johan ^a  

^a LUND UNIVERSITY   (Sweden)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYCLIC AMP; FORSKOLIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1ALPHA; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEINASE ACTIVATED RECEPTOR 2; THROMBIN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE INDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; INFLAMMATION; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR GENE;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; BLOTTING, NORTHERN; CELL ADHESION MOLECULES; CELL LINE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DNA PROBES; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; FORSKOLIN; HUMANS; INFLAMMATION; INTERLEUKIN-1; KINETICS; LIPOPOLYSACCHARIDES; RECEPTOR, PAR-2; RECEPTORS, CELL SURFACE; RECEPTORS, THROMBIN; RECOMBINANT PROTEINS; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS;

BACTERIA (MICROORGANISMS); RICKETTSIA SP. PAR;

EID: 15844401726     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.25.14910     Document Type: Article

References (31)

1. Pober, J. S., and Cotran, R. S. (1990) Transplantation 50, 427-451
2. Springer, T. A. (1995) Anna. Rev. Physiol. 57, 827-872
3. Nawroth, P. P., and Stern, D. M. (1986) J. Exp. Med. 163, 740-745
4. Moore, K. L., Esmon, C. T., and Esmon, N. L. (1989) Blood 73, 159-165
5. Bevilacqua, M. P., Pober, J. S., Majeau, G. R., Cotran, R. S., and Gimbrone, M. A., Jr. (1984) J. Eicp. Med. 160, 618-623
6. Moore, K. L., Andreoli, S. P., Esmon, N. L., Esmon, C. T., and Bang, N. U. (1989) J. Clin. Invest. 79, 124-130
7. Rollins, B. R., Yoshimura, T., Leonard, E. J., and Pober, J. S. (1990) Am. J. Pathol. 136, 1229-1233
8. Strieter, R. M., Kunkel, S. L., Showell, H. J., Remick, D. G., Phan, S. H., Ward, P. A., and Marks, R. M. (1989) Science 243, 1467-1469
9. Bevilacqua, M. P., Stengelin, S., Gimbrone, M. A., Jr., and Seed, B. (1989) Science 243, 1160-1165
10. Pober, J. S., Gimbrone, M. A., Jr., Lapierre, L. A., Mendrick, D. L., Fiers, W., Rothlein, R., and Springer, T. A. (1986) J. Immunol. 137, 1893-1896
11. Osborn, L., Hession, C., Tizard, R., Vassallo, C., Luhowskyj, S., Chi-Rosso, G., and Lobb, R. (1989) Cell 59, 1203-1211
12. Royall, J. A., Berkow, R. L., Beckman, J. S., Cunningham, M. C., Matalon, S., and Freeman, B. A. (1989) Am. J. Physiol. 257, L399-L410
13. Berman, R. S., Frew, J. D., and Martin, W. (1993) Br. J. Pharmacol. 110, 1282-1284
14. Nystedt, S., Emilsson, K., Wahlestedt, C., and Sundelin, J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9208-9212
15. Nystedt, S., Larsson, A.-K., Åberg, H., and Sundelin, J. (1995) J. Biol. Chem. 270, 5950-5955
16. Nystedt, S., Emilsson, K., Larsson, A.-K., Strömbeck, B., and Sundelin, J. (1995) Eur. J. Biochem. 232, 84-89
17. Vu, T.-K: H., Hung, D. T., Wheaton, V. I., and Coughlin, S. R. (1991) Cell 64, 1057-1068
18. Rasmussen, U. B., Vouret-Craviari, V., Jallat, S., Schlesinger, Y., Pagès, G., Pavirani, A., Lecocq, J.-P., Pouysségur, J., and Van Obberghen-Schilling, E. (1991) FEBS Lett. 288, 123-128
19. Vu, T.-K. H., Wheaton, V. I., Hung, D. T., Charo, I., and Coughlin, S. R. (1991) Nature 353, 674-677
20. Chen, J., Ishii, M., Wang, L., Ishii, K., and Coughlin, S. R. (1994) J. Biol. Chem. 269, 16041-16045
21. Jaffe, E. A., Nachman, R. L., Becker, C. G., and Minick, C. R. (1973) J. Clin. Invest. 52, 2745-2756
22. Xie, W., and Rothblum, L. I. (1991) BioTechmques 11, 325-327
23. Norton, K. J., Scarborough, R. M., Kutok, J. L., Escobedo, M.-A., Nannizzi, L., and Coller, B. S. (1993) Blood 82, 2125-2136
24. Pober, J. S., Slowik, M. R., De Luca, L. G., and Ritchie, A. J. (1993) J. Immunol. 150, 5114-5123
25. Koga, S., Morris, S. Ogawa, S., Liao, H., Bilezikian, J. P., Chen, G., Thompson, W. J., Ashikaga, T., Brett, J., Stern, D. M., and Pinsky, D. J. (1995) Am. J. Physiol. 268, C1104-C1113
26. DeLuca, L. G., Johnson, D. R., Whitley, M. Z., Collins, T., and Pober, J. S. (1994) J. Biol. Chem. 269, 19193-19196
27. Hein, L., Ishii, K., Coughlin, S. R., and Kobilka, B. K. (1994) J. Biol. Chem. 269, 27719-27726
28. Horvat, R., and Palade, G. E. (1995) J. Cell Sci. 108, 1155-1164
29. Woolkalis, M. J., DeMelfi, T. M., Jr., Blanchard, N., Hoxie, J. A., and Brass, L. F. (1995) J. Biol. Chem. 270, 9868-9875
30. Soifer, S. J., Peters, K. G., O'Keefe, J., and Coughlin, S. R. (1994) Am. J. Pathol. 144, 60-69
31. Zacharias, U., Xu, Y., Hagège, J., Sraer, J.-D., Brass, L. F., and Rondeau, E. (1995) J. Biol. Chem. 270, 545-550