-
1
-
-
0020570701
-
Monocyte chemotaxis: Stimulation by specific exosite region in thrombin
-
Bar-Shavit R, Mudd M, Wilner G, Mann K, Fenton JW II. 1983. Monocyte chemotaxis: stimulation by specific exosite region in thrombin. Science 220:728-731.
-
(1983)
Science
, vol.220
, pp. 728-731
-
-
Bar-Shavit, R.1
Mudd, M.2
Wilner, G.3
Mann, K.4
Fenton J.W. II5
-
2
-
-
0028085095
-
Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture
-
Beecher KL, Andersen TT, Fenton JW II. 1994. Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture. J Neurosci Res 37:108-115.
-
(1994)
J Neurosci Res
, vol.37
, pp. 108-115
-
-
Beecher, K.L.1
Andersen, T.T.2
Fenton J.W. II3
-
3
-
-
0021264972
-
Structure-function relationship in human alpha- and gamma-thrombin
-
Berliner LJ. 1984. Structure-function relationship in human alpha- and gamma-thrombin. Mol Cell Biochem 61:159-172.
-
(1984)
Mol Cell Biochem
, vol.61
, pp. 159-172
-
-
Berliner, L.J.1
-
4
-
-
0002906957
-
Platelet membrane proteins: Composition and receptor function
-
Gordon J, editor. Amsterdam: Elsevier/North Holland
-
Berndt M, Philipps D. 1981. Platelet membrane proteins: composition and receptor function. In: Gordon J, editor. Platelets in biology and pathology. Amsterdam: Elsevier/North Holland 198:43-47.
-
(1981)
Platelets in Biology and Pathology
, vol.198
, pp. 43-47
-
-
Berndt, M.1
Philipps, D.2
-
5
-
-
0028067683
-
The anion-binding exosite is critical for the high affinity binding of the thrombin receptor
-
Blackhart BD, Cuenco G, Toda T, Scaborough RM, Wolf DL, Ramakrishnan V. 1994. The anion-binding exosite is critical for the high affinity binding of the thrombin receptor. Growth Factors 11:17-28.
-
(1994)
Growth Factors
, vol.11
, pp. 17-28
-
-
Blackhart, B.D.1
Cuenco, G.2
Toda, T.3
Scaborough, R.M.4
Wolf, D.L.5
Ramakrishnan, V.6
-
6
-
-
0025255579
-
Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1
-
Cavanaugh KP, Gurwitz D, Cunningham DD, Bradshaw RA. 1990. Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J Neurochem 54:1735-1743.
-
(1990)
J Neurochem
, vol.54
, pp. 1735-1743
-
-
Cavanaugh, Kp.1
Gurwitz, D.2
Cunningham, D.D.3
Bradshaw, R.A.4
-
7
-
-
0030612752
-
The G12 coupled thrombin receptor stimulates mitogenesis through the sh2 domain
-
Collins LR, Ricketts WA, Olefsky JM, Brown JH. 1997. The G12 coupled thrombin receptor stimulates mitogenesis through the SH2 domain. Oncogene 15:595-600.
-
(1997)
Oncogene
, vol.15
, pp. 595-600
-
-
Collins, L.R.1
Ricketts, W.A.2
Olefsky, J.M.3
Brown, J.H.4
-
8
-
-
0028243478
-
Characterization of a stable form of human meizothrombin derived from recombinant prothrombin (R 155A, R271A, R284A)
-
Coté HCF, Stevens WK, Bajzar L, Banfield DK, Nesheim ME, MacGillivray RTM. 1994. Characterization of a stable form of human meizothrombin derived from recombinant prothrombin (R 155A, R271A, R284A). J Biol Chem 269:11374-11380.
-
(1994)
J Biol Chem
, vol.269
, pp. 11374-11380
-
-
Coté, H.C.F.1
Stevens, W.K.2
Bajzar, L.3
Banfield, D.K.4
Nesheim, M.E.5
Macgillivray, R.T.M.6
-
10
-
-
0025857712
-
Prothrombin mRNA is expressed by cells of the nervous system
-
Dihanich M, Kaser M, Reinhard E, Cunningham D, Monard D. 1991. Prothrombin mRNA is expressed by cells of the nervous system. Neuron 6:575-581.
-
(1991)
Neuron
, vol.6
, pp. 575-581
-
-
Dihanich, M.1
Kaser, M.2
Reinhard, E.3
Cunningham, D.4
Monard, D.5
-
11
-
-
0019729451
-
Thrombin specificity
-
Fenton JW. 1981. Thrombin specificity. Ann N Y Acad Sci 370:468-495.
-
(1981)
Ann N Y Acad Sci
, vol.370
, pp. 468-495
-
-
Fenton, J.W.1
-
12
-
-
0030007646
-
Thrombin, its receptor and protease nexin 1, its potent serpin, in the nervous system
-
Festoff BW, Smirnova IV, Ma JX, Citron BA. 1996. Thrombin, its receptor and protease nexin 1, its potent serpin, in the nervous system. Semin Thromb Hemost 22:267-271.
-
(1996)
Semin Thromb Hemost
, vol.22
, pp. 267-271
-
-
Festoff, B.W.1
Smirnova, I.V.2
Ma, J.X.3
Citron, B.A.4
-
14
-
-
0019305915
-
Thrombin active-site regions required for fibroblast receptor binding and initiation of cell division
-
Glenn K, Carney D, Fenton J, Cunningham D. 1980. Thrombin active-site regions required for fibroblast receptor binding and initiation of cell division. J Biol Chem 255:6609-6616.
-
(1980)
J Biol Chem
, vol.255
, pp. 6609-6616
-
-
Glenn, K.1
Carney, D.2
Fenton, J.3
Cunningham, D.4
-
15
-
-
0023829715
-
Plasminogen activator and inhibitor activity in human glioblastoma cells and modulation by sodium pyruvate
-
Gross JL, Behrens DL, Mullins DE, Korublith PL, Dexter DL. 1988. Plasminogen activator and inhibitor activity in human glioblastoma cells and modulation by sodium pyruvate. Cancer Res 48:291-296.
-
(1988)
Cancer Res
, vol.48
, pp. 291-296
-
-
Gross, J.L.1
Behrens, D.L.2
Mullins, D.E.3
Korublith, P.L.4
Dexter, D.L.5
-
17
-
-
0011811083
-
Thrombin modulates and reverses neuroblastoma neurite outgrowth
-
Gurwitz D, Cunningham D. 1988. Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc Natl Acad Sci USA 85:3440-3444.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 3440-3444
-
-
Gurwitz, D.1
Cunningham, D.2
-
18
-
-
0000194758
-
Thrombin generation, an essential step in haemostasis and thrombosis
-
Bloom AL, Forbes CD, Thomas DP, Tuddenhani EGD, editors. Edinburgh: Churchill Livingstone.
-
Hemker HC. 1993. Thrombin generation, an essential step in haemostasis and thrombosis. In: Bloom AL, Forbes CD, Thomas DP, Tuddenhani EGD, editors. Haemostasis and thrombosis. Edinburgh: Churchill Livingstone. p. 477-490.
-
(1993)
Haemostasis and Thrombosis
, pp. 477-490
-
-
Hemker, H.C.1
-
19
-
-
0027990395
-
Serine proteases and their serpin inhibitors in Alzheimer's disease
-
Ho GJ, Smirnova IV, Akaaboune M, Hantai D, Festoff BW. 1994. Serine proteases and their serpin inhibitors in Alzheimer's disease. Biomed Pharmacother 48:296-304.
-
(1994)
Biomed Pharmacother
, vol.48
, pp. 296-304
-
-
Ho, G.J.1
Smirnova, I.V.2
Akaaboune, M.3
Hantai, D.4
Festoff, B.W.5
-
20
-
-
0030979972
-
Protease-activated receptor 3 is a second thrombin receptor in humans
-
Ishihara H, Conolly AW, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, Coughlin SR. 1997. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 386:502-506.
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
Conolly, A.W.2
Zeng, D.3
Kahn, M.L.4
Zheng, Y.W.5
Timmons, C.6
Tram, T.7
Coughlin, S.R.8
-
21
-
-
0032514474
-
A dual thrombin receptor system for platelet activation
-
Kahn ML, Zheng YW, Huang W, Bigornia V, Zeng DW, Moff S, Farese RV, Tam C, Couhlin SR. 1998. A dual thrombin receptor system for platelet activation. Nature 349:690-694.
-
(1998)
Nature
, vol.349
, pp. 690-694
-
-
Kahn, M.L.1
Zheng, Y.W.2
Huang, W.3
Bigornia, V.4
Zeng, D.W.5
Moff, S.6
Farese, R.V.7
Tam, C.8
Couhlin, S.R.9
-
22
-
-
0033559805
-
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
-
Kahn ML, Nakanishi-Matsui, Shapiro MJ, Ishihara I, Coughlin SH. 1999. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest 103:879-887.
-
(1999)
J Clin Invest
, vol.103
, pp. 879-887
-
-
Kahn, M.L.1
Nakanishi-Matsui2
Shapiro, M.J.3
Ishihara, I.4
Coughlin, S.H.5
-
23
-
-
0030448707
-
6 cells
-
6 cells. J Neurosci Res 46:641-651.
-
(1996)
J Neurosci Res
, vol.46
, pp. 641-651
-
-
Kaufmann, R.1
Lindschau, C.2
Höer, A.3
Adomeit, A.4
Haller, H.5
Liebmann, C.6
Oberdisse, E.7
Henklein, P.8
Nowak, G.9
-
24
-
-
0032498917
-
Functional thrombin receptor PAR1 in primary cultures of human glioblastoma cells
-
Kaufmann R, Patt S, Schafberg H, Kalff R, Neupert G, Nowak G. 1998a. Functional thrombin receptor PAR1 in primary cultures of human glioblastoma cells. NeuroReport 9:709-712.
-
(1998)
Neuroreport
, vol.9
, pp. 709-712
-
-
Kaufmann, R.1
Patt, S.2
Schafberg, H.3
Kalff, R.4
Neupert, G.5
Nowak, G.6
-
25
-
-
0031733527
-
Intermediates of prothrombin activation induce intracellular calcium mobilization in rat aortic smooth muscle cells
-
Kaufmann R, Hoffmann J, Ramakrishnan V, Nowak G.1998b. Intermediates of prothrombin activation induce intracellular calcium mobilization in rat aortic smooth muscle cells. Thromb Haemost 80:1018-1021.
-
(1998)
Thromb Haemost
, vol.80
, pp. 1018-1021
-
-
Kaufmann, R.1
Hoffmann, J.2
Ramakrishnan, V.3
Nowak, G.4
-
26
-
-
0033041111
-
PAR 1-type thrombin receptors are involved in thrombin-induced calcium signaling in human meningioma cells
-
Kaufmann R, Patt S, Kraft R, Zieger M, Henklein P, Neupert G, Nowak G. 1999. PAR 1-type thrombin receptors are involved in thrombin-induced calcium signaling in human meningioma cells. J Neuro-Oncol 42:131-136.
-
(1999)
J Neuro-oncol
, vol.42
, pp. 131-136
-
-
Kaufmann, R.1
Patt, S.2
Kraft, R.3
Zieger, M.4
Henklein, P.5
Neupert, G.6
Nowak, G.7
-
27
-
-
0022975591
-
The prothrombinase-catalyzed activation of prothrombin proceeds through the intermediate meizothrombin in an ordered, sequential reaction
-
Krishnaswamy S, Mann KG, Nesheim ME. 1986. The prothrombinase-catalyzed activation of prothrombin proceeds through the intermediate meizothrombin in an ordered, sequential reaction. J Biol Chem 261: 8977-8984.
-
(1986)
J Biol Chem
, vol.261
, pp. 8977-8984
-
-
Krishnaswamy, S.1
Mann, K.G.2
Nesheim, M.E.3
-
28
-
-
0032562675
-
Requirement for rho-mediated myosin light chain phosphorylation in thrombm-stimulated cell rounding and its dissociation from mitogenesis
-
Majumdar M, Seasholtz TM, Goldstein D, de Lanerolle P, Brown JH. 1998. Requirement for rho-mediated myosin light chain phosphorylation in thrombm-stimulated cell rounding and its dissociation from mitogenesis. J Biol Chem 237:10099-10106.
-
(1998)
J Biol Chem
, vol.237
, pp. 10099-10106
-
-
Majumdar, M.1
Seasholtz, T.M.2
Goldstein, D.3
De Lanerolle, P.4
Brown, J.H.5
-
29
-
-
0029143923
-
Mechanism of thrombin receptor agonist specifity. Chimeric receptors and complementary mutations identify an agonist recognition site
-
Nanevicz T, Ishii M, Wang L, Chen M, Chen J, Turck CW, Cohen F, Coughlin SR. 1995. Mechanism of thrombin receptor agonist specifity. Chimeric receptors and complementary mutations identify an agonist recognition site. J Biol Chem 270:21619-21625.
-
(1995)
J Biol Chem
, vol.270
, pp. 21619-21625
-
-
Nanevicz, T.1
Ishii, M.2
Wang, L.3
Chen, M.4
Chen, J.5
Turck, C.W.6
Cohen, F.7
Coughlin, S.R.8
-
30
-
-
0026684801
-
Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo
-
Nierodzik ML, Kajumo LR, Karpatkin S. 1992. Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo. Cancer Res 52:3267-3272.
-
(1992)
Cancer Res
, vol.52
, pp. 3267-3272
-
-
Nierodzik, M.L.1
Kajumo, L.R.2
Karpatkin, S.3
-
32
-
-
0024263049
-
Meizothrombin, a major product of factor xa-catalyzed prothrombin activation
-
Rosing J, Tans G. 1988. Meizothrombin, a major product of factor Xa-catalyzed prothrombin activation. Thromb Haemost 60:335-360.
-
(1988)
Thromb Haemost
, vol.60
, pp. 335-360
-
-
Rosing, J.1
Tans, G.2
-
33
-
-
0023010704
-
Formation of meizothrombin as an intermediate in factor Xa-catalyzed prothrombin activation
-
Rosing J, Zwaal RFA, Tans G. 1986. Formation of meizothrombin as an intermediate in factor Xa-catalyzed prothrombin activation. J Biol Chem 261:4224-4228.
-
(1986)
J Biol Chem
, vol.261
, pp. 4224-4228
-
-
Rosing, J.1
Zwaal, R.F.A.2
Tans, G.3
-
34
-
-
0025329390
-
The structure of a complex of recombinant hirudin and human α-thrombin
-
Rydel TJ, Ravichandran KG, Tulinsky A, Bode W, Huber R, Roitch C, Fenton II JW. 1990. The structure of a complex of recombinant hirudin and human α-thrombin. Science 249:277-280.
-
(1990)
Science
, vol.249
, pp. 277-280
-
-
Rydel, T.J.1
Ravichandran, K.G.2
Tulinsky, A.3
Bode, W.4
Huber, R.5
Roitch, C.6
Fenton J.W. II7
-
35
-
-
0030883750
-
Cloning of PAR3 from human platelets, and human erythroleukemic and human promonocytic cell lines
-
Scase TJ. Heath MF. Evans RJ. 1997. Cloning of PAR3 from human platelets, and human erythroleukemic and human promonocytic cell lines. Blood 90:2113-2114.
-
(1997)
Blood
, vol.90
, pp. 2113-2114
-
-
Scase, T.J.1
Heath, M.F.2
Evans, R.J.3
-
36
-
-
0028027469
-
Extravascular protcolysis and the nervous system: Serine protease/serpin balance
-
Smirnova IV, Ho GJ, Fenton JWI, Festoff BW. 1994. Extravascular protcolysis and the nervous system: serine protease/serpin balance. Semin Thromb Hemost 20:426-432.
-
(1994)
Semin Thromb Hemost
, vol.20
, pp. 426-432
-
-
Smirnova, I.V.1
Ho, G.J.2
Fenton, J.W.I.3
Festoff, B.W.4
-
37
-
-
0026519282
-
Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors
-
Suidan HS, Stone SR, Hemmings BA, Monard D. 1992. Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors. Neuron 8:363-375.
-
(1992)
Neuron
, vol.8
, pp. 363-375
-
-
Suidan, H.S.1
Stone, S.R.2
Hemmings, B.A.3
Monard, D.4
-
39
-
-
0025840544
-
Meizothrombin formation during factor Xa-catalyzed prothrombin activation. Formation in a purified system and in plasma
-
Tans G, Janssen-Claessen T, Hemker HC, Zwall RFA, Rosing J. 1991. Meizothrombin formation during factor Xa-catalyzed prothrombin activation. Formation in a purified system and in plasma. J Biol Chem 266: 21864-21873.
-
(1991)
J Biol Chem
, vol.266
, pp. 21864-21873
-
-
Tans, G.1
Janssen-Claessen, T.2
Hemker, H.C.3
Zwall, R.F.A.4
Rosing, J.5
-
40
-
-
0027980113
-
Plasmin modulates die thrombin-evoked calcium response in C6 glioma cells
-
Turner JS, Redpath GT, Humphries JE, Gonias SL, Vandenberg SR. 1994. Plasmin modulates die thrombin-evoked calcium response in C6 glioma cells. Biochem J 297:175-179.
-
(1994)
Biochem J
, vol.297
, pp. 175-179
-
-
Turner, J.S.1
Redpath, G.T.2
Humphries, J.E.3
Gonias, S.L.4
Vandenberg, S.R.5
-
41
-
-
0032100686
-
1-inducing protease-activated receptors (PAR-1 and PAR-2) in rat astrocytes and C6 glioma cells
-
1-inducing protease-activated receptors (PAR-1 and PAR-2) in rat astrocytes and C6 glioma cells. Neuroscience 86:597-609.
-
(1998)
Neuroscience
, vol.86
, pp. 597-609
-
-
Ubl, J.J.1
Vöhringer, C.2
Reiser, G.3
-
42
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel mechanism of receptor activation
-
Vu T-K, Hung DT, Wheaton VI, Coughlin SR. 1991. Molecular cloning of a functional thrombin receptor reveals a novel mechanism of receptor activation. Cell 64:1057-1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.-K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
43
-
-
0343196695
-
Neuroligand-triggered calcium signalling in cultured human glioma cells
-
Weidt P, Möller T, Labrakakis C, Patt S, Kettenmann H. 1997. Neuroligand-triggered calcium signalling in cultured human glioma cells. Neurosci Lett 228:91-94.
-
(1997)
Neurosci Lett
, vol.228
, pp. 91-94
-
-
Weidt, P.1
Möller, T.2
Labrakakis, C.3
Patt, S.4
Kettenmann, H.5
-
44
-
-
0029145574
-
Morphologic, immunologic, biochemical, and cytogenetic characteristics of the human glioblastoma-derived cell line, SNB-19
-
Welch WC, Morrison RS, Gross JL, Gollin SM, Kitson RB, Goldfarb RH, Giuliano KA, Bradley MK, Kornblith PL. 1995. Morphologic, immunologic, biochemical, and cytogenetic characteristics of the human glioblastoma-derived cell line, SNB-19. In Vitro Cell Dev Biol-Animal 31:610-616.
-
(1995)
In Vitro Cell Dev Biol-Animal
, vol.31
, pp. 610-616
-
-
Welch, W.C.1
Morrison, R.S.2
Gross, J.L.3
Gollin, S.M.4
Kitson, R.B.5
Goldfarb, R.H.6
Giuliano, K.A.7
Bradley, M.K.8
Kornblith, P.L.9
-
45
-
-
0032499696
-
Cloning and characterization of human protease-activated receptor 4
-
Xu W-F, Andersen H, Whitmore TE, Presnell SR, Yee DP, Ching A, Gilbert T, Davie EA, Foster CA. 1998. Cloning and characterization of human protease-activated receptor 4. Proc Natl Acad Sci USA 95:6642-6664.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6642-6664
-
-
Xu, W.-F.1
Andersen, H.2
Whitmore, T.E.3
Presnell, S.R.4
Yee, D.P.5
Ching, A.6
Gilbert, T.7
Davie, E.A.8
Foster, C.A.9
|