The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells

EMBO Journal

Volumn 20, Issue 22, 2001, Pages 6540-6549

  Niedernhofer, Laura J ^a   Essers, Jeroen ^a   Weeda, Geert ^a   Beverloo, Berna ^a   De Wit, Jan ^a   Muijtjens, Manja ^a   Odijk, Hanny ^a   Hoeijmakers, Jan H J ^a   Kanaar, Roland ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

D loops; Double strand breaks; Heterology; Homologous recombination

Indexed keywords

ENDONUCLEASE; PROTEIN ERCC1 XPF; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DNA REPAIR; DNA STRUCTURE; ENZYME SPECIFICITY; EXCISION REPAIR; GENE TARGETING; GENETIC RECOMBINATION; MOLECULAR STABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

ANIMALS; CELL LINE; CLONING, MOLECULAR; DNA DAMAGE; DNA REPAIR; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; EMBRYO; ENDONUCLEASES; EXONS; GAMMA RAYS; GENE LIBRARY; GENE TARGETING; GENOTYPE; HELA CELLS; HUMANS; IMMUNOBLOTTING; METHYL METHANESULFONATE; MICE; MODELS, GENETIC; MUTAGENS; PROTEINS; RECOMBINATION, GENETIC; SISTER CHROMATID EXCHANGE; STEM CELLS;

ANIMALIA; MAMMALIA;

EID: 0035890270     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.22.6540     Document Type: Article

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