-
1
-
-
0030887862
-
RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination
-
Agrawal A., and Schatz D.G. RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination. Cell 89 (1997) 43-53
-
(1997)
Cell
, vol.89
, pp. 43-53
-
-
Agrawal, A.1
Schatz, D.G.2
-
2
-
-
0036713424
-
Cancer predisposition and hematopoietic failure in Rad50(S/S) mice
-
Bender C.F., Sikes M.L., Sullivan R., Huye L.E., Le Beau M.M., Roth D.B., Mirzoeva O.K., Oltz E.M., and Petrini J.H. Cancer predisposition and hematopoietic failure in Rad50(S/S) mice. Genes Dev. 16 (2002) 2237-2251
-
(2002)
Genes Dev.
, vol.16
, pp. 2237-2251
-
-
Bender, C.F.1
Sikes, M.L.2
Sullivan, R.3
Huye, L.E.4
Le Beau, M.M.5
Roth, D.B.6
Mirzoeva, O.K.7
Oltz, E.M.8
Petrini, J.H.9
-
3
-
-
46249131123
-
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
-
Bennardo N., Cheng A., Huang N., and Stark J.M. Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet. 4 (2008) e1000110
-
(2008)
PLoS Genet.
, vol.4
-
-
Bennardo, N.1
Cheng, A.2
Huang, N.3
Stark, J.M.4
-
4
-
-
0032247578
-
Hairpin coding end opening is mediated by RAG1 and RAG2 proteins
-
Besmer E., Mansilia-Soto J., Cassard S., Sawchuk D.J., Brown G., Sadofsky M., Lewis S.M., Nussenzweig M.C., and Cortes P. Hairpin coding end opening is mediated by RAG1 and RAG2 proteins. Mol. Cell 2 (1998) 817-828
-
(1998)
Mol. Cell
, vol.2
, pp. 817-828
-
-
Besmer, E.1
Mansilia-Soto, J.2
Cassard, S.3
Sawchuk, D.J.4
Brown, G.5
Sadofsky, M.6
Lewis, S.M.7
Nussenzweig, M.C.8
Cortes, P.9
-
5
-
-
0028960511
-
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation
-
Blunt T., Finnie N.J., Taccioli G.E., Smith G.C.M., Demengeot J., Gottlieb T.M., Mizuta R., Varghese A.J., Alt F.W., Jeggo P.A., and Jackson S.P. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 80 (1995) 813-823
-
(1995)
Cell
, vol.80
, pp. 813-823
-
-
Blunt, T.1
Finnie, N.J.2
Taccioli, G.E.3
Smith, G.C.M.4
Demengeot, J.5
Gottlieb, T.M.6
Mizuta, R.7
Varghese, A.J.8
Alt, F.W.9
Jeggo, P.A.10
Jackson, S.P.11
-
6
-
-
0029881698
-
p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes
-
Bogue M.A., Zhu C., Aguilar-Cordova E., Donehower L.A., and Roth D.B. p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes. Genes Dev. 10 (1996) 553-565
-
(1996)
Genes Dev.
, vol.10
, pp. 553-565
-
-
Bogue, M.A.1
Zhu, C.2
Aguilar-Cordova, E.3
Donehower, L.A.4
Roth, D.B.5
-
7
-
-
0030837472
-
V(D)J recombination in Ku86-deficient mice: Distinct effects on coding, signal, and hybrid joint formation
-
Bogue M.A., Wang C., Zhu C., and Roth D.B. V(D)J recombination in Ku86-deficient mice: Distinct effects on coding, signal, and hybrid joint formation. Immunity 7 (1997) 37-47
-
(1997)
Immunity
, vol.7
, pp. 37-47
-
-
Bogue, M.A.1
Wang, C.2
Zhu, C.3
Roth, D.B.4
-
8
-
-
0032438115
-
Analysis of variable (diversity) joining recombination in DNA-dependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation
-
Bogue M.A., Jhappan C., and Roth D.B. Analysis of variable (diversity) joining recombination in DNA-dependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation. Proc. Natl. Acad. Sci. USA 95 (1998) 15559-15564
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15559-15564
-
-
Bogue, M.A.1
Jhappan, C.2
Roth, D.B.3
-
9
-
-
0020663062
-
A severe combined immunodeficiency mutation in the mouse
-
Bosma G.C., Custer R.P., and Bosma M.J. A severe combined immunodeficiency mutation in the mouse. Nature 301 (1983) 527-530
-
(1983)
Nature
, vol.301
, pp. 527-530
-
-
Bosma, G.C.1
Custer, R.P.2
Bosma, M.J.3
-
10
-
-
33747097562
-
ATM stabilizes DNA double-strand-break complexes during V(D)J recombination
-
Bredemeyer A.L., Sharma G.G., Huang C.-Y., Helmink B.A., Walker L.M., Khor K.C., Nuskey B., Sullivan K.E., Pandita T.K., Bassing C.H., and Sleckman B.P. ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature 442 (2006) 466-470
-
(2006)
Nature
, vol.442
, pp. 466-470
-
-
Bredemeyer, A.L.1
Sharma, G.G.2
Huang, C.-Y.3
Helmink, B.A.4
Walker, L.M.5
Khor, K.C.6
Nuskey, B.7
Sullivan, K.E.8
Pandita, T.K.9
Bassing, C.H.10
Sleckman, B.P.11
-
11
-
-
0031664401
-
Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11
-
Bressan D.A., Olivares H.A., Nelms B.E., and Petrini J.H. Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11. Genetics 150 (1998) 591-600
-
(1998)
Genetics
, vol.150
, pp. 591-600
-
-
Bressan, D.A.1
Olivares, H.A.2
Nelms, B.E.3
Petrini, J.H.4
-
12
-
-
52949109260
-
Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation
-
Buis J., Wu Y., Deng Y., Leddon J., Westfield G., Eckersdorff M., Sekiguchi J.M., Chang S., and Ferguson D.O. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell 135 (2008) 85-96
-
(2008)
Cell
, vol.135
, pp. 85-96
-
-
Buis, J.1
Wu, Y.2
Deng, Y.3
Leddon, J.4
Westfield, G.5
Eckersdorff, M.6
Sekiguchi, J.M.7
Chang, S.8
Ferguson, D.O.9
-
13
-
-
0032076248
-
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
-
Carney J.P., Maser R.S., Olivares H., Davis E.M., Le Beau M., Yates III J.R., Hays L., Morgan W.F., and Petrini J.H. The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response. Cell 93 (1998) 477-486
-
(1998)
Cell
, vol.93
, pp. 477-486
-
-
Carney, J.P.1
Maser, R.S.2
Olivares, H.3
Davis, E.M.4
Le Beau, M.5
Yates III, J.R.6
Hays, L.7
Morgan, W.F.8
Petrini, J.H.9
-
14
-
-
0026018228
-
T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor delta gene recombination
-
Carroll A.M., and Bosma M.J. T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor delta gene recombination. Genes Dev. 5 (1991) 1357-1366
-
(1991)
Genes Dev.
, vol.5
, pp. 1357-1366
-
-
Carroll, A.M.1
Bosma, M.J.2
-
15
-
-
0034623860
-
Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX
-
Chen H.T., Bhandoola A., Difilippantonio M.J., Zhu J., Brown M.J., Tai X., Rogakou E.P., Brotz T.M., Bonner W.M., Ried T., and Nussenzweig A. Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX. Science 290 (2000) 1962-1965
-
(2000)
Science
, vol.290
, pp. 1962-1965
-
-
Chen, H.T.1
Bhandoola, A.2
Difilippantonio, M.J.3
Zhu, J.4
Brown, M.J.5
Tai, X.6
Rogakou, E.P.7
Brotz, T.M.8
Bonner, W.M.9
Ried, T.10
Nussenzweig, A.11
-
16
-
-
34848843525
-
Rag mutations reveal robust alternative end joining
-
Corneo B., Wendland R.L., Deriano L., Cui X., Klein I.A., Wong S.Y., Arnal S., Holub A.J., Weller G.R., Pancake B.A., et al. Rag mutations reveal robust alternative end joining. Nature 449 (2007) 483-486
-
(2007)
Nature
, vol.449
, pp. 483-486
-
-
Corneo, B.1
Wendland, R.L.2
Deriano, L.3
Cui, X.4
Klein, I.A.5
Wong, S.Y.6
Arnal, S.7
Holub, A.J.8
Weller, G.R.9
Pancake, B.A.10
-
17
-
-
0035930329
-
Human Rad50/Mre11 is a flexible complex that can tether DNA ends
-
de Jager M., van Noort J., van Gent D.C., Dekker C., Kanaar R., and Wyman C. Human Rad50/Mre11 is a flexible complex that can tether DNA ends. Mol. Cell 8 (2001) 1129-1135
-
(2001)
Mol. Cell
, vol.8
, pp. 1129-1135
-
-
de Jager, M.1
van Noort, J.2
van Gent, D.C.3
Dekker, C.4
Kanaar, R.5
Wyman, C.6
-
18
-
-
34250200743
-
Defective signal joint recombination in fanconi anemia fibroblasts reveals a role for Rad50 in V(D)J recombination
-
Donahue S.L., Tabah A.A., Schmitz K., Aaron A., and Campbell C. Defective signal joint recombination in fanconi anemia fibroblasts reveals a role for Rad50 in V(D)J recombination. J. Mol. Biol. 370 (2007) 449-458
-
(2007)
J. Mol. Biol.
, vol.370
, pp. 449-458
-
-
Donahue, S.L.1
Tabah, A.A.2
Schmitz, K.3
Aaron, A.4
Campbell, C.5
-
19
-
-
0032167446
-
A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for Ku in V(D)J recombination
-
Gao Y., Chaudhuri J., Zhu C., Davidson L., Weaver D.T., and Alt F.W. A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for Ku in V(D)J recombination. Immunity 9 (1998) 367-376
-
(1998)
Immunity
, vol.9
, pp. 367-376
-
-
Gao, Y.1
Chaudhuri, J.2
Zhu, C.3
Davidson, L.4
Weaver, D.T.5
Alt, F.W.6
-
20
-
-
33748089029
-
DNA-PK autophosphorylation facilitates Artemis endonuclease activity
-
Goodarzi A.A., Yu Y., Riballo E., Douglas P., Walker S.A., Ye R., Harer C., Marchetti C., Morrice N., Jeggo P.A., and Lees-Miller S.P. DNA-PK autophosphorylation facilitates Artemis endonuclease activity. EMBO J. 25 (2006) 3880-3889
-
(2006)
EMBO J.
, vol.25
, pp. 3880-3889
-
-
Goodarzi, A.A.1
Yu, Y.2
Riballo, E.3
Douglas, P.4
Walker, S.A.5
Ye, R.6
Harer, C.7
Marchetti, C.8
Morrice, N.9
Jeggo, P.A.10
Lees-Miller, S.P.11
-
21
-
-
2942525595
-
Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells
-
Guirouilh-Barbat J., Huck S., Bertrand P., Pirzio L., Desmaze C., Sabatier L., and Lopez B.S. Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells. Mol. Cell 14 (2004) 611-623
-
(2004)
Mol. Cell
, vol.14
, pp. 611-623
-
-
Guirouilh-Barbat, J.1
Huck, S.2
Bertrand, P.3
Pirzio, L.4
Desmaze, C.5
Sabatier, L.6
Lopez, B.S.7
-
22
-
-
38049187905
-
Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends
-
Guirouilh-Barbat J., Rass E., Plo I., Bertrand P., and Lopez B.S. Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends. Proc. Natl. Acad. Sci. USA 104 (2007) 20902-20907
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20902-20907
-
-
Guirouilh-Barbat, J.1
Rass, E.2
Plo, I.3
Bertrand, P.4
Lopez, B.S.5
-
24
-
-
0035085624
-
Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome
-
Harfst E., Cooper S., Neubauer S., Distel L., and Grawunder U. Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome. Mol. Immunol. 37 (2000) 915-929
-
(2000)
Mol. Immunol.
, vol.37
, pp. 915-929
-
-
Harfst, E.1
Cooper, S.2
Neubauer, S.3
Distel, L.4
Grawunder, U.5
-
25
-
-
63449084054
-
MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
-
Helmink B.A., Bredemeyer A.L., Lee B.S., Huang C.Y., Sharma G.G., Walker L.M., Bednarski J.J., Lee W.L., Pandita T.K., Bassing C.H., and Sleckman B.P. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. J. Exp. Med. 206 (2009) 669-679
-
(2009)
J. Exp. Med.
, vol.206
, pp. 669-679
-
-
Helmink, B.A.1
Bredemeyer, A.L.2
Lee, B.S.3
Huang, C.Y.4
Sharma, G.G.5
Walker, L.M.6
Bednarski, J.J.7
Lee, W.L.8
Pandita, T.K.9
Bassing, C.H.10
Sleckman, B.P.11
-
26
-
-
0023659483
-
Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V(D)J joining signals
-
Hesse J.E., Lieber M.R., Gellert M., and Mizuuchi K. Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V(D)J joining signals. Cell 49 (1987) 775-783
-
(1987)
Cell
, vol.49
, pp. 775-783
-
-
Hesse, J.E.1
Lieber, M.R.2
Gellert, M.3
Mizuuchi, K.4
-
27
-
-
0030964130
-
A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage
-
Hiom K., and Gellert M. A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage. Cell 88 (1997) 65-72
-
(1997)
Cell
, vol.88
, pp. 65-72
-
-
Hiom, K.1
Gellert, M.2
-
28
-
-
0032084698
-
Assembly of a 12/23 paired signal complex: A critical control point in V(D)J recombination
-
Hiom K., and Gellert M. Assembly of a 12/23 paired signal complex: A critical control point in V(D)J recombination. Mol. Cell 1 (1998) 1011-1019
-
(1998)
Mol. Cell
, vol.1
, pp. 1011-1019
-
-
Hiom, K.1
Gellert, M.2
-
29
-
-
0035906860
-
Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase
-
Hopfner K.P., Karcher A., Craig L., Woo T.T., Carney J.P., and Tainer J.A. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell 105 (2001) 473-485
-
(2001)
Cell
, vol.105
, pp. 473-485
-
-
Hopfner, K.P.1
Karcher, A.2
Craig, L.3
Woo, T.T.4
Carney, J.P.5
Tainer, J.A.6
-
30
-
-
0036682314
-
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair
-
Hopfner K.P., Craig L., Moncalian G., Zinkel R.A., Usui T., Owen B.A., Karcher A., Henderson B., Bodmer J.L., McMurray C.T., et al. The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair. Nature 418 (2002) 562-566
-
(2002)
Nature
, vol.418
, pp. 562-566
-
-
Hopfner, K.P.1
Craig, L.2
Moncalian, G.3
Zinkel, R.A.4
Usui, T.5
Owen, B.A.6
Karcher, A.7
Henderson, B.8
Bodmer, J.L.9
McMurray, C.T.10
-
31
-
-
0037086702
-
Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair
-
Kang J., Bronson R.T., and Xu Y. Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J. 21 (2002) 1447-1455
-
(2002)
EMBO J.
, vol.21
, pp. 1447-1455
-
-
Kang, J.1
Bronson, R.T.2
Xu, Y.3
-
32
-
-
0024791338
-
Junctional sequences of T cell receptor gÎ genes: Implications for gÎ T cell lineages and for a novel intermediate of V(D)J joining
-
Lafaille J.J., DeCloux A., Bonneville M., Takagaki Y., and Tonegawa S. Junctional sequences of T cell receptor gÎ genes: Implications for gÎ T cell lineages and for a novel intermediate of V(D)J joining. Cell 59 (1989) 859-870
-
(1989)
Cell
, vol.59
, pp. 859-870
-
-
Lafaille, J.J.1
DeCloux, A.2
Bonneville, M.3
Takagaki, Y.4
Tonegawa, S.5
-
33
-
-
0033380368
-
Mutational analysis of RAG-1 and RAG-2 identifies three active site amino acids in RAG-1 critical for both cleavage steps of V(D)J recombination
-
Landree M.A., Wibbenmeyer J.A., and Roth D.B. Mutational analysis of RAG-1 and RAG-2 identifies three active site amino acids in RAG-1 critical for both cleavage steps of V(D)J recombination. Genes Dev. 13 (1999) 3059-3069
-
(1999)
Genes Dev.
, vol.13
, pp. 3059-3069
-
-
Landree, M.A.1
Wibbenmeyer, J.A.2
Roth, D.B.3
-
34
-
-
1942421722
-
RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination
-
Lee G.S., Neiditch M.B., Salus S.S., and Roth D.B. RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination. Cell 117 (2004) 171-184
-
(2004)
Cell
, vol.117
, pp. 171-184
-
-
Lee, G.S.1
Neiditch, M.B.2
Salus, S.S.3
Roth, D.B.4
-
35
-
-
34548401682
-
Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining
-
Lee K., and Lee S.E. Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining. Genetics 176 (2007) 2003-2014
-
(2007)
Genetics
, vol.176
, pp. 2003-2014
-
-
Lee, K.1
Lee, S.E.2
-
36
-
-
0024255703
-
Novel strand exchanges in V(D)J recombination
-
Lewis S.M., Hesse J.E., Mizuuchi K., and Gellert M. Novel strand exchanges in V(D)J recombination. Cell 55 (1988) 1099-1107
-
(1988)
Cell
, vol.55
, pp. 1099-1107
-
-
Lewis, S.M.1
Hesse, J.E.2
Mizuuchi, K.3
Gellert, M.4
-
37
-
-
13544259957
-
Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation
-
Li L., Salido E., Zhou Y., Bhattacharyya S., Yannone S.M., Dunn E., Meneses J., Feeney A.J., and Cowan M.J. Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation. J. Immunol. 174 (2005) 2420-2428
-
(2005)
J. Immunol.
, vol.174
, pp. 2420-2428
-
-
Li, L.1
Salido, E.2
Zhou, Y.3
Bhattacharyya, S.4
Yannone, S.M.5
Dunn, E.6
Meneses, J.7
Feeney, A.J.8
Cowan, M.J.9
-
38
-
-
0036850786
-
The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development
-
Liang H.E., Hsu L.Y., Cado D., Cowell L.G., Kelsoe G., and Schlissel M.S. The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development. Immunity 17 (2002) 639-651
-
(2002)
Immunity
, vol.17
, pp. 639-651
-
-
Liang, H.E.1
Hsu, L.Y.2
Cado, D.3
Cowell, L.G.4
Kelsoe, G.5
Schlissel, M.S.6
-
39
-
-
0037169325
-
The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
-
Lobachev K.S., Gordenin D.A., and Resnick M.A. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell 108 (2002) 183-193
-
(2002)
Cell
, vol.108
, pp. 183-193
-
-
Lobachev, K.S.1
Gordenin, D.A.2
Resnick, M.A.3
-
40
-
-
0037155703
-
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
-
Ma Y., Pannicke U., Schwarz K., and Lieber M.R. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108 (2002) 781-794
-
(2002)
Cell
, vol.108
, pp. 781-794
-
-
Ma, Y.1
Pannicke, U.2
Schwarz, K.3
Lieber, M.R.4
-
41
-
-
0242468933
-
Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences
-
Ma J.L., Kim E.M., Haber J.E., and Lee S.E. Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences. Mol. Cell. Biol. 23 (2003) 8820-8828
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8820-8828
-
-
Ma, J.L.1
Kim, E.M.2
Haber, J.E.3
Lee, S.E.4
-
42
-
-
0032085295
-
The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks
-
Paull T.T., and Gellert M. The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks. Mol. Cell 1 (1998) 969-979
-
(1998)
Mol. Cell
, vol.1
, pp. 969-979
-
-
Paull, T.T.1
Gellert, M.2
-
43
-
-
0034612307
-
A mechanistic basis for Mre11-directed DNA joining at microhomologies
-
Paull T.T., and Gellert M. A mechanistic basis for Mre11-directed DNA joining at microhomologies. Proc. Natl. Acad. Sci. USA 97 (2000) 6409-6414
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6409-6414
-
-
Paull, T.T.1
Gellert, M.2
-
44
-
-
0025294780
-
T cell receptor gene rearrangements in functional T cell clones from severe combined immunodeficient (scid) mice: Reversion of the scid phenotype in individual lymphocyte progenitors
-
Petrini J.H., Carroll A.M., and Bosma M.J. T cell receptor gene rearrangements in functional T cell clones from severe combined immunodeficient (scid) mice: Reversion of the scid phenotype in individual lymphocyte progenitors. Proc. Natl. Acad. Sci. USA 87 (1990) 3450-3453
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3450-3453
-
-
Petrini, J.H.1
Carroll, A.M.2
Bosma, M.J.3
-
45
-
-
0028801363
-
Formation and resolution of double-strand break intermediates in V(D)J rearrangement
-
Ramsden D.A., and Gellert M. Formation and resolution of double-strand break intermediates in V(D)J rearrangement. Genes Dev. 9 (1995) 2409-2420
-
(1995)
Genes Dev.
, vol.9
, pp. 2409-2420
-
-
Ramsden, D.A.1
Gellert, M.2
-
46
-
-
0036932453
-
Leaky scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice
-
Rooney S., Sekiguchi J.M., Zhu C., Cheng H., Manis J., Whitlow S., DeVido J., Foy D., Chaudhuri J., Lombard D., and Alt F.W. Leaky scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice. Mol. Cell 10 (2002) 1379-1390
-
(2002)
Mol. Cell
, vol.10
, pp. 1379-1390
-
-
Rooney, S.1
Sekiguchi, J.M.2
Zhu, C.3
Cheng, H.4
Manis, J.5
Whitlow, S.6
DeVido, J.7
Foy, D.8
Chaudhuri, J.9
Lombard, D.10
Alt, F.W.11
-
47
-
-
0141720776
-
Restraining the V(D)J recombinase
-
Roth D.B. Restraining the V(D)J recombinase. Nat. Rev. Immunol. 3 (2003) 656-666
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 656-666
-
-
Roth, D.B.1
-
48
-
-
0022976432
-
Nonhomologous recombination in mammalian cells: Role for short sequence homologies in the joining reaction
-
Roth D.B., and Wilson J.H. Nonhomologous recombination in mammalian cells: Role for short sequence homologies in the joining reaction. Mol. Cell. Biol. 6 (1986) 4295-4304
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 4295-4304
-
-
Roth, D.B.1
Wilson, J.H.2
-
49
-
-
0026792892
-
V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
-
Roth D.B., Menetski J.P., Nakajima P.B., Bosma M.J., and Gellert M. V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes. Cell 70 (1992) 983-991
-
(1992)
Cell
, vol.70
, pp. 983-991
-
-
Roth, D.B.1
Menetski, J.P.2
Nakajima, P.B.3
Bosma, M.J.4
Gellert, M.5
-
50
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori A.A., Lukas C., Coates J., Mistrik M., Fu S., Bartek J., Baer R., Lukas J., and Jackson S.P. Human CtIP promotes DNA end resection. Nature 450 (2007) 509-514
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
Bartek, J.6
Baer, R.7
Lukas, J.8
Jackson, S.P.9
-
51
-
-
0035697242
-
Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs
-
Sekiguchi J.A., Whitlow S., and Alt F.W. Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs. Mol. Cell 8 (2001) 1383-1390
-
(2001)
Mol. Cell
, vol.8
, pp. 1383-1390
-
-
Sekiguchi, J.A.1
Whitlow, S.2
Alt, F.W.3
-
52
-
-
0032973315
-
DNA hairpin opening mediated by the RAG1 and RAG2 proteins
-
Shockett P.E., and Schatz D.G. DNA hairpin opening mediated by the RAG1 and RAG2 proteins. Mol. Cell. Biol. 19 (1999) 4159-4166
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4159-4166
-
-
Shockett, P.E.1
Schatz, D.G.2
-
53
-
-
34447288912
-
Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination
-
Soulas-Sprauel P., Le Guyader G., Rivera-Munoz P., Abramowski V., Olivier-Martin C., Goujet-Zalc C., Charneau P., and de Villartay J.P. Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination. J. Exp. Med. 204 (2007) 1717-1727
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1717-1727
-
-
Soulas-Sprauel, P.1
Le Guyader, G.2
Rivera-Munoz, P.3
Abramowski, V.4
Olivier-Martin, C.5
Goujet-Zalc, C.6
Charneau, P.7
de Villartay, J.P.8
-
54
-
-
0033544724
-
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder
-
Stewart G.S., Maser R.S., Stankovic T., Bressan D.A., Kaplan M.I., Jaspers N.G., Raams A., Byrd P.J., Petrini J.H., and Taylor A.M. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder. Cell 99 (1999) 577-587
-
(1999)
Cell
, vol.99
, pp. 577-587
-
-
Stewart, G.S.1
Maser, R.S.2
Stankovic, T.3
Bressan, D.A.4
Kaplan, M.I.5
Jaspers, N.G.6
Raams, A.7
Byrd, P.J.8
Petrini, J.H.9
Taylor, A.M.10
-
55
-
-
3242891189
-
The Mre11 complex and the metabolism of chromosome breaks: The importance of communicating and holding things together
-
Stracker T.H., Theunissen J.W., Morales M., and Petrini J.H. The Mre11 complex and the metabolism of chromosome breaks: The importance of communicating and holding things together. DNA Repair (Amst.) 3 (2004) 845-854
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 845-854
-
-
Stracker, T.H.1
Theunissen, J.W.2
Morales, M.3
Petrini, J.H.4
-
56
-
-
58249100111
-
Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability
-
Stracker T.H., Williams B.R., Deriano L., Theunissen J.W., Adelman C.A., Roth D.B., and Petrini J.H. Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability. Mol. Cell. Biol. 29 (2009) 503-514
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 503-514
-
-
Stracker, T.H.1
Williams, B.R.2
Deriano, L.3
Theunissen, J.W.4
Adelman, C.A.5
Roth, D.B.6
Petrini, J.H.7
-
57
-
-
4344571097
-
Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice
-
Talukder S.R., Dudley D.D., Alt F.W., Takahama Y., and Akamatsu Y. Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice. Nucleic Acids Res. 32 (2004) 4539-4549
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 4539-4549
-
-
Talukder, S.R.1
Dudley, D.D.2
Alt, F.W.3
Takahama, Y.4
Akamatsu, Y.5
-
58
-
-
0000770165
-
Nijmegen breakage syndrome. The International Nijmegen Breakage Syndrome Study Group
-
The International Nijmegen Breakage Syndrome Study Group
-
The International Nijmegen Breakage Syndrome Study Group. Nijmegen breakage syndrome. The International Nijmegen Breakage Syndrome Study Group. Arch. Dis. Child. 82 (2000) 400-406
-
(2000)
Arch. Dis. Child.
, vol.82
, pp. 400-406
-
-
-
59
-
-
33745192808
-
Methods for studying the cellular response to DNA damage: Influence of the Mre11 complex on chromosome metabolism
-
Theunissen J.W., and Petrini J.H. Methods for studying the cellular response to DNA damage: Influence of the Mre11 complex on chromosome metabolism. Methods Enzymol. 409 (2006) 251-284
-
(2006)
Methods Enzymol.
, vol.409
, pp. 251-284
-
-
Theunissen, J.W.1
Petrini, J.H.2
-
60
-
-
0346156075
-
Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice
-
Theunissen J.W., Kaplan M.I., Hunt P.A., Williams B.R., Ferguson D.O., Alt F.W., and Petrini J.H. Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice. Mol. Cell 12 (2003) 1511-1523
-
(2003)
Mol. Cell
, vol.12
, pp. 1511-1523
-
-
Theunissen, J.W.1
Kaplan, M.I.2
Hunt, P.A.3
Williams, B.R.4
Ferguson, D.O.5
Alt, F.W.6
Petrini, J.H.7
-
61
-
-
38049125555
-
The endless tale of non-homologous end-joining
-
Weterings E., and Chen D.J. The endless tale of non-homologous end-joining. Cell Res. 18 (2008) 114-124
-
(2008)
Cell Res.
, vol.18
, pp. 114-124
-
-
Weterings, E.1
Chen, D.J.2
-
62
-
-
0037117410
-
A murine model of Nijmegen breakage syndrome
-
Williams B.R., Mirzoeva O.K., Morgan W.F., Lin J., Dunnick W., and Petrini J.H. A murine model of Nijmegen breakage syndrome. Curr. Biol. 12 (2002) 648-653
-
(2002)
Curr. Biol.
, vol.12
, pp. 648-653
-
-
Williams, B.R.1
Mirzoeva, O.K.2
Morgan, W.F.3
Lin, J.4
Dunnick, W.5
Petrini, J.H.6
-
64
-
-
34748863465
-
IgH class switching and translocations use a robust non-classical end-joining pathway
-
Yan C.T., Boboila C., Souza E.K., Franco S., Hickernell T.R., Murphy M., Gumaste S., Geyer M., Zarrin A.A., Manis J.P., et al. IgH class switching and translocations use a robust non-classical end-joining pathway. Nature 449 (2007) 478-482
-
(2007)
Nature
, vol.449
, pp. 478-482
-
-
Yan, C.T.1
Boboila, C.2
Souza, E.K.3
Franco, S.4
Hickernell, T.R.5
Murphy, M.6
Gumaste, S.7
Geyer, M.8
Zarrin, A.A.9
Manis, J.P.10
-
65
-
-
0000858524
-
V(D)J rearrangement in Nijmegen breakage syndrome
-
Yeo T.C., Xia D., Hassouneh S., Yang X.O., Sabath D.E., Sperling K., Gatti R.A., Concannon P., and Willerford D.M. V(D)J rearrangement in Nijmegen breakage syndrome. Mol. Immunol. 37 (2000) 1131-1139
-
(2000)
Mol. Immunol.
, vol.37
, pp. 1131-1139
-
-
Yeo, T.C.1
Xia, D.2
Hassouneh, S.3
Yang, X.O.4
Sabath, D.E.5
Sperling, K.6
Gatti, R.A.7
Concannon, P.8
Willerford, D.M.9
-
66
-
-
27544434114
-
The Mre11/Rad50/Xrs2 complex and non-homologous end-joining of incompatible ends in S. cerevisiae
-
Zhang X., and Paull T.T. The Mre11/Rad50/Xrs2 complex and non-homologous end-joining of incompatible ends in S. cerevisiae. DNA Repair (Amst.) 4 (2005) 1281-1294
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 1281-1294
-
-
Zhang, X.1
Paull, T.T.2
-
67
-
-
0030576534
-
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
-
Zhu C., Bogue M.A., Lim D.-S., Hasty P., and Roth D.B. Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86 (1996) 379-389
-
(1996)
Cell
, vol.86
, pp. 379-389
-
-
Zhu, C.1
Bogue, M.A.2
Lim, D.-S.3
Hasty, P.4
Roth, D.B.5
-
68
-
-
0037188898
-
Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations
-
Zhu C., Mills K.D., Ferguson D.O., Lee C., Manis J., Fleming J., Gao Y., Morton C.C., and Alt F.W. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell 109 (2002) 811-821
-
(2002)
Cell
, vol.109
, pp. 811-821
-
-
Zhu, C.1
Mills, K.D.2
Ferguson, D.O.3
Lee, C.4
Manis, J.5
Fleming, J.6
Gao, Y.7
Morton, C.C.8
Alt, F.W.9
|