The human TREX2 3′ → 5→-exonuclease structure suggests a mechanism for efficient nonprocessive DNA catalysis

Journal of Biological Chemistry

Volumn 280, Issue 15, 2005, Pages 15212-15218

  Perrino, Fred W ^a   Harvey, Scott ^a   McMillin, Sara ^a   Hollis, Thomas ^a  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BINDING ENERGY; CATALYSIS; CELLS; DNA; MOLECULAR BIOLOGY; STRUCTURE (COMPOSITION);

ACTIVE SITES; BINDING CAPACITY; NUCLEOTIDES; SEQUENCE IDENTITY;

PROTEINS;

ALANINE; ARGININE; BACTERIAL PROTEIN; DNA; DNA Q PROTEIN; EXONUCLEASE; PROTEIN; TREX 2 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; DIMERIZATION; DNA BINDING; DNA FLANKING REGION; DNA STRAND; DNA STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENETIC CONSERVATION; INDUCED MUTATION; PRIORITY JOURNAL; PROTEIN FAMILY; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

ALANINE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ARGININE; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DNA; DNA MUTATIONAL ANALYSIS; DNA POLYMERASE III; DNA REPAIR; ELECTRONS; ESCHERICHIA COLI PROTEINS; EXODEOXYRIBONUCLEASES; EXONUCLEASES; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHOPROTEINS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINATION, GENETIC; SEQUENCE HOMOLOGY, AMINO ACID;

BACTERIA (MICROORGANISMS);

EID: 17644407757     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500108200     Document Type: Article

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