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Volumn 23, Issue 2, 2003, Pages 733-743

Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT PROTEIN;

EID: 0037221249     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.2.733-743.2003     Document Type: Article
Times cited : (96)

References (54)
  • 1
    • 0028928854 scopus 로고
    • Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase
    • Araki, K., M. Araki, J. Miyazaki, and P. Vassalli. 1995. Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. Proc. Natl. Acad. Sci. USA 92:160-164.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 160-164
    • Araki, K.1    Araki, M.2    Miyazaki, J.3    Vassalli, P.4
  • 2
    • 0030818573 scopus 로고    scopus 로고
    • Distribution of the Rad51 recombinase in human and mouse spermatocytes
    • Barlow, A. L., F. E. Benson, S. C. West, and M. A. Hulten. 1997. Distribution of the Rad51 recombinase in human and mouse spermatocytes. EMBO J. 16:5207-5215.
    • (1997) EMBO J. , vol.16 , pp. 5207-5215
    • Barlow, A.L.1    Benson, F.E.2    West, S.C.3    Hulten, M.A.4
  • 3
    • 0031829611 scopus 로고    scopus 로고
    • Crossing over analysis at pachytene in man
    • Barlow, A. L., and M. A. Hulten. 1998. Crossing over analysis at pachytene in man. Eur. J. Hum. Genet. 6:350-358.
    • (1998) Eur. J. Hum. Genet. , vol.6 , pp. 350-358
    • Barlow, A.L.1    Hulten, M.A.2
  • 4
    • 0036088977 scopus 로고    scopus 로고
    • The Mouse Genome Database (MGD): The model organism database for the laboratory mouse
    • Blake, J. A., J. E. Richardson, C. J. Bult, J. A. Kadin, and J. T. Eppig. 2002. The Mouse Genome Database (MGD): The model organism database for the laboratory mouse. Nucleic Acids Res. 30:113-115.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 113-115
    • Blake, J.A.1    Richardson, J.E.2    Bult, C.J.3    Kadin, J.A.4    Eppig, J.T.5
  • 5
    • 0025315699 scopus 로고
    • A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae
    • Cao, L., E. Alani, and N. Kleckner. 1990. A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae. Cell 61:1089-1101.
    • (1990) Cell , vol.61 , pp. 1089-1101
    • Cao, L.1    Alani, E.2    Kleckner, N.3
  • 8
    • 0032922005 scopus 로고    scopus 로고
    • The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast
    • Chen, W., and S. Jinks-Robertson. 1999. The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast. Genetics 151:1299-1313.
    • (1999) Genetics , vol.151 , pp. 1299-1313
    • Chen, W.1    Jinks-Robertson, S.2
  • 11
    • 0035695023 scopus 로고    scopus 로고
    • Recombination at double-strand breaks and DNA ends: Conserved mechanisms from phage to humans
    • Cromie, G. A., J. C. Connelly, and D. R. Leach. 2001. Recombination at double-strand breaks and DNA ends: Conserved mechanisms from phage to humans. Mol. Cell 8:1163-1174.
    • (2001) Mol. Cell , vol.8 , pp. 1163-1174
    • Cromie, G.A.1    Connelly, J.C.2    Leach, D.R.3
  • 12
    • 0035081417 scopus 로고    scopus 로고
    • Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells
    • Elliott, B., and M. Jasin. 2001. Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells. Mol. Cell. Biol, 21:2671-2682.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2671-2682
    • Elliott, B.1    Jasin, M.2
  • 13
    • 0028859379 scopus 로고
    • Somatic intragenic recombination within the mutated locus BLM can correct the high sister-chromatid exchange phenotype of Bloom syndrome cells
    • Ellis, N. A., D. J. Lennon, M. Proytcheva, B. Alhadeff, E. E. Henderson, and J. German. 1995. Somatic intragenic recombination within the mutated locus BLM can correct the high sister-chromatid exchange phenotype of Bloom syndrome cells. Am. J. Hum. Genet. 57:1019-1027.
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 1019-1027
    • Ellis, N.A.1    Lennon, D.J.2    Proytcheva, M.3    Alhadeff, B.4    Henderson, E.E.5    German, J.6
  • 14
    • 0025362253 scopus 로고
    • Molecular evidence that homologous recombination occurs in proliferating human somatic cells
    • Groden, J., Y. Nakamura, and J. German. 1990. Molecular evidence that homologous recombination occurs in proliferating human somatic cells. Proc. Natl. Acad. Sci. USA 87:4315-4319.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4315-4319
    • Groden, J.1    Nakamura, Y.2    German, J.3
  • 15
    • 0033020244 scopus 로고    scopus 로고
    • Mitotic recombination map of 13cen-13q14 derived from an investigation of loss of heterozygosity in retinoblastomas
    • Hagstrom, S. A., and T. P. Dryja. 1999. Mitotic recombination map of 13cen-13q14 derived from an investigation of loss of heterozygosity in retinoblastomas. Proc. Natl. Acad. Sci. USA 96:2952-2957.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2952-2957
    • Hagstrom, S.A.1    Dryja, T.P.2
  • 16
    • 0034613170 scopus 로고    scopus 로고
    • The relationship between homology length and crossing over during the repair of a broken chromosome
    • Inbar, O., B. Liefshitz, G. Bitan, and M. Kupiec. 2000. The relationship between homology length and crossing over during the repair of a broken chromosome. J. Biol. Chem. 275:30833-30838.
    • (2000) J. Biol. Chem. , vol.275 , pp. 30833-30838
    • Inbar, O.1    Liefshitz, B.2    Bitan, G.3    Kupiec, M.4
  • 17
    • 0000840620 scopus 로고    scopus 로고
    • Double-strand break repair and homologous recombination in mammalian cells
    • J. A. Nickoloff and M. F. Hoekstra (ed.), Humana Press, Totowa, N.J.
    • Jasin, M. 2001. Double-strand break repair and homologous recombination in mammalian cells, p. 207-235. In J. A. Nickoloff and M. F. Hoekstra (ed.), DNA damage and repair, vol. 3. Humana Press, Totowa, N.J.
    • (2001) DNA Damage and Repair , vol.3 , pp. 207-235
    • Jasin, M.1
  • 18
    • 0002698563 scopus 로고    scopus 로고
    • LOH and mitotic recombination
    • M. Ehrlich (ed.). Eaton Publishing, Natick, Mass
    • Jasin, M. 2000. LOH and mitotic recombination, p. 191-209. In M. Ehrlich (ed.), DNA Alterations in Cancer. Eaton Publishing, Natick, Mass.
    • (2000) DNA Alterations in Cancer , pp. 191-209
    • Jasin, M.1
  • 19
    • 0034600975 scopus 로고    scopus 로고
    • Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
    • Johnson, R. D., and M. Jasin. 2000. Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. EMBO J. 19:3398-3407.
    • (2000) EMBO J. , vol.19 , pp. 3398-3407
    • Johnson, R.D.1    Jasin, M.2
  • 20
    • 0035223878 scopus 로고    scopus 로고
    • Mechanism and control of meiotic recombination initiation
    • Keeney, S. 2001. Mechanism and control of meiotic recombination initiation. Curr. Top. Dev. Biol. 52:1-53.
    • (2001) Curr. Top. Dev. Biol. , vol.52 , pp. 1-53
    • Keeney, S.1
  • 22
    • 0027422291 scopus 로고
    • Site-specific recombinases: Tools for genome engineering
    • Kilby, N. J., M. R. Snaith, and J. A. Murray. 1993. Site-specific recombinases: Tools for genome engineering. Trends Genet. 9:413-421.
    • (1993) Trends Genet. , vol.9 , pp. 413-421
    • Kilby, N.J.1    Snaith, M.R.2    Murray, J.A.3
  • 23
    • 0030459140 scopus 로고    scopus 로고
    • The role of DNA methylation in cancer genetic and epigenetics
    • Laird, P. W., and R. Jaenisch. 1996. The role of DNA methylation in cancer genetic and epigenetics. Annu. Rev. Genet. 30:441-464.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 441-464
    • Laird, P.W.1    Jaenisch, R.2
  • 24
    • 3142544243 scopus 로고
    • Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome
    • Langlois, R. G., W. L. Bigbee, R. H. Jensen, and J. German. 1989. Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome. Proc. Natl. Acad. Sci. USA 86:670-674.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 670-674
    • Langlois, R.G.1    Bigbee, W.L.2    Jensen, R.H.3    German, J.4
  • 25
    • 0026335851 scopus 로고
    • Loss of constitutional heterozygosity in human cancer
    • Lasko, D., W. Cavenee, and M. Nordenskjold. 1991. Loss of constitutional heterozygosity in human cancer. Annu. Rev. Genet. 25:281-314.
    • (1991) Annu. Rev. Genet. , vol.25 , pp. 281-314
    • Lasko, D.1    Cavenee, W.2    Nordenskjold, M.3
  • 26
    • 0035093218 scopus 로고    scopus 로고
    • Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity
    • Lefebvre, L., N. Dionne, J. Karaskova, J. A. Squire, and A. Nagy. 2001. Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity. Nat. Genet. 27:257-258.
    • (2001) Nat. Genet. , vol.27 , pp. 257-258
    • Lefebvre, L.1    Dionne, N.2    Karaskova, J.3    Squire, J.A.4    Nagy, A.5
  • 28
    • 0036338128 scopus 로고    scopus 로고
    • Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells
    • Liu, P., N. A. Jenkins, and N. G. Copeland. 2002. Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells. Nat. Genet. 30:66-72.
    • (2002) Nat. Genet. , vol.30 , pp. 66-72
    • Liu, P.1    Jenkins, N.A.2    Copeland, N.G.3
  • 31
    • 0029947714 scopus 로고    scopus 로고
    • Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication
    • Malkova, A., E. L. Ivanov, and J. E. Haber. 1996. Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication. Proc. Natl. Acad. Sci. USA 93:7131-7136.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7131-7136
    • Malkova, A.1    Ivanov, E.L.2    Haber, J.E.3
  • 32
    • 0034687691 scopus 로고    scopus 로고
    • HO endonuclease-induced recombination in yeast meiosis resembles Spo11-induced events
    • Malkova, A., F. Klein, W. Y. Leung, and J. E. Haber. 2000. HO endonuclease-induced recombination in yeast meiosis resembles Spo11-induced events. Proc. Natl. Acad. Sci. USA 97:14500-14505.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14500-14505
    • Malkova, A.1    Klein, F.2    Leung, W.Y.3    Haber, J.E.4
  • 33
    • 0037089080 scopus 로고    scopus 로고
    • The time course and chromosomal localization of recombination-related proteins at meiosis in the mouse are compatible with models that can resolve the early DNA-DNA interactions without reciprocal recombination
    • Moens, P. B., N. K. Kolas, M. Tarsounas, E. Marcon, P. E. Cohen, and B. Spyropoulos. 2002, The time course and chromosomal localization of recombination-related proteins at meiosis in the mouse are compatible with models that can resolve the early DNA-DNA interactions without reciprocal recombination, J. Cell Sci. 115:1611-1622.
    • (2002) J. Cell Sci. , vol.115 , pp. 1611-1622
    • Moens, P.B.1    Kolas, N.K.2    Tarsounas, M.3    Marcon, E.4    Cohen, P.E.5    Spyropoulos, B.6
  • 34
    • 0035874894 scopus 로고    scopus 로고
    • Homology-directed DNA repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation
    • Moynahan, M. E., T. Y. Cui, and M. Jasin. 2001. Homology-directed DNA repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. Cancer Res. 61:4842-4850.
    • (2001) Cancer Res. , vol.61 , pp. 4842-4850
    • Moynahan, M.E.1    Cui, T.Y.2    Jasin, M.3
  • 35
    • 0030797563 scopus 로고    scopus 로고
    • Loss of heterozygosity induced by a chromosomal double-strand break
    • Moynahan, M. E., and M. Jasin. 1997. Loss of heterozygosity induced by a chromosomal double-strand break. Proc. Natl. Acad. Sci. USA 94:8988-8993.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8988-8993
    • Moynahan, M.E.1    Jasin, M.2
  • 36
    • 0035099044 scopus 로고    scopus 로고
    • BRCA2 is required for homology-directed repair of chromosomal breaks
    • Moynahan, M. E., A. J. Pierce, and M. Jasin. 2001. BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell 7:263-272.
    • (2001) Mol. Cell , vol.7 , pp. 263-272
    • Moynahan, M.E.1    Pierce, A.J.2    Jasin, M.3
  • 37
    • 0028197257 scopus 로고
    • Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair
    • Nassif, N., J. Penney, S. Pal, W. R. Engels, and G. B. Gloor. 1994. Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair. Mol. Cell. Biol. 14:1613-1625.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1613-1625
    • Nassif, N.1    Penney, J.2    Pal, S.3    Engels, W.R.4    Gloor, G.B.5
  • 38
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Pâques, F., and J. E. Haber. 1999. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 63:349-404.
    • (1999) Microbiol. Mol. Biol. Rev. , vol.63 , pp. 349-404
    • Pâques, F.1    Haber, J.E.2
  • 39
    • 0035893363 scopus 로고    scopus 로고
    • Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
    • Pierce, A. J., P. Hu, M. Han, N. Ellis, and M. Jasin. 2001, Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev. 15:3237-3242.
    • (2001) Genes Dev. , vol.15 , pp. 3237-3242
    • Pierce, A.J.1    Hu, P.2    Han, M.3    Ellis, N.4    Jasin, M.5
  • 40
    • 0034971182 scopus 로고    scopus 로고
    • Interchromosomal gene conversion at an endogenous human cell locus
    • Quintana, P. J., E. A. Neuwirth, and A. J. Grosovsky. 2001. Interchromosomal gene conversion at an endogenous human cell locus. Genetics 158:757-767.
    • (2001) Genetics , vol.158 , pp. 757-767
    • Quintana, P.J.1    Neuwirth, E.A.2    Grosovsky, A.J.3
  • 41
    • 0035369401 scopus 로고    scopus 로고
    • Fragile and unstable chromosomes in cancer: Causes and consequences
    • Richards, R. I. 2001. Fragile and unstable chromosomes in cancer: Causes and consequences. Trends Genet. 17:339-345.
    • (2001) Trends Genet. , vol.17 , pp. 339-345
    • Richards, R.I.1
  • 42
    • 0034621854 scopus 로고    scopus 로고
    • Frequent chromosomal translocations induced by DNA double-strand breaks
    • Richardson, C., and M. Jasin. 2000. Frequent chromosomal translocations induced by DNA double-strand breaks. Nature 405:697-700.
    • (2000) Nature , vol.405 , pp. 697-700
    • Richardson, C.1    Jasin, M.2
  • 43
    • 0032535036 scopus 로고    scopus 로고
    • Double-strand break repair by interchromosomal recombination: Suppression of chromosomal translocations
    • Richardson, C., M. E. Moynahan, and M. Jasin. 1998. Double-strand break repair by interchromosomal recombination: Suppression of chromosomal translocations. Genes Dev. 12:3831-3842.
    • (1998) Genes Dev. , vol.12 , pp. 3831-3842
    • Richardson, C.1    Moynahan, M.E.2    Jasin, M.3
  • 44
    • 0033569602 scopus 로고    scopus 로고
    • Cloning, characterization, and localization of mouse and human SPO11
    • Romanienko, P. J., and R. D. Camerini-Otero. 1999. Cloning, characterization, and localization of mouse and human SPO11. Genomics 61:156-169.
    • (1999) Genomics , vol.61 , pp. 156-169
    • Romanienko, P.J.1    Camerini-Otero, R.D.2
  • 47
    • 0034975493 scopus 로고    scopus 로고
    • Mitotic recombination is suppressed by chromosomal divergence in hybrids of distantly related mouse strains
    • Shao, C., P. J. Stambrook, and J. A. Tischfield. 2001. Mitotic recombination is suppressed by chromosomal divergence in hybrids of distantly related mouse strains. Nat. Genet. 28:169-172.
    • (2001) Nat. Genet. , vol.28 , pp. 169-172
    • Shao, C.1    Stambrook, P.J.2    Tischfield, J.A.3
  • 48
    • 0035000154 scopus 로고    scopus 로고
    • Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break
    • Signon, L., A. Malkova, M. L. Naylor, H. Klein, and J. E. Haber. 2001. Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol. Cell. Biol. 21:2048-2056.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2048-2056
    • Signon, L.1    Malkova, A.2    Naylor, M.L.3    Klein, H.4    Haber, J.E.5
  • 49
    • 0037036354 scopus 로고    scopus 로고
    • ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair
    • Stark, J. M., P. Hu, A. J. Pierce, M. E. Moynahan, N. Ellis, and M. Jasin. 2002. ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair. J. Biol. Chem. 277:20185-20194.
    • (2002) J. Biol. Chem. , vol.277 , pp. 20185-20194
    • Stark, J.M.1    Hu, P.2    Pierce, A.J.3    Moynahan, M.E.4    Ellis, N.5    Jasin, M.6
  • 50
    • 0020541955 scopus 로고
    • The double-strand-break repair model for recombination
    • Szostak, J. W., T. L. Orr-Weaver, R. J. Rothstein, and F. W. Stahl. 1983. The double-strand-break repair model for recombination. Cell 33:25-35.
    • (1983) Cell , vol.33 , pp. 25-35
    • Szostak, J.W.1    Orr-Weaver, T.L.2    Rothstein, R.J.3    Stahl, F.W.4
  • 51
    • 0026771287 scopus 로고
    • Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs
    • te Riele, H., E. R. Maandag, and A. Berns. 1992. Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc. Natl. Acad. Sci. USA 89:5128-5132.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5128-5132
    • Te Riele, H.1    Maandag, E.R.2    Berns, A.3


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