-
1
-
-
0029916122
-
A human peptidyl-prolyl isomerase essential for regulation of mitosis
-
DOI 10.1038/380544a0
-
Lu, K.P., Hanes, S.D. and Hunter, T. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature 1996, 380(6574): 544-7. (Pubitemid 26111332)
-
(1996)
Nature
, vol.380
, Issue.6574
, pp. 544-547
-
-
Lu, K.P.1
Hanes, S.D.2
Hunter, T.3
-
2
-
-
0642347849
-
The peptidyl-prolyl isomerase Pin1
-
Joseph, J.D., Yeh, E.S., Swenson, K.I., Means, A.R. and Winkler, K.E. The peptidyl-prolyl isomerase Pin1. Prog Cell Cycle Res 2003, 5: 477-487
-
(2003)
Prog Cell Cycle Res
, vol.5
, pp. 477-487
-
-
Joseph, J.D.1
Yeh, E.S.2
Swenson, K.I.3
Means, A.R.4
Winkler, K.E.5
-
3
-
-
0031438929
-
Sequence-specific and phosphorylation dependent proline isomerization: A potential mitotic regulatory mechanism
-
DOI 10.1126/science.278.5345.1957
-
Yaffe, M.B., Schutkowski, M., Shen, M. et al. Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science 1997, 278(5345): 1957-1960 (Pubitemid 28013239)
-
(1997)
Science
, vol.278
, Issue.5345
, pp. 1957-1960
-
-
Yaffe, M.B.1
Schutkowski, M.2
Shen, M.3
Zhou, X.Z.4
Stukenberg, P.T.5
Rahfeld, J.-U.6
Xu, J.7
Kuang, J.8
Kirschner, M.W.9
Fischer, G.10
Cantley, L.C.11
Lu, K.P.12
-
4
-
-
0036535975
-
Pinning down proline-directed phosphorylation signaling
-
Lu, K.P., Liou, Y.C. and Zhou, X.Z. Pinning down proline-directed phosphorylation signaling. Trends Cell Biol 2002, 12(4): 164-172
-
(2002)
Trends Cell Biol
, vol.12
, Issue.4
, pp. 164-172
-
-
Lu, K.P.1
Liou, Y.C.2
Zhou, X.Z.3
-
5
-
-
0008233581
-
Structural and functional analysis of the mitotic rotamase Pinl suggests substrate recognition is phosphorylation dependent
-
Ranganathan, R., Lu, K.P., Hunter, T. and Noel, J.P. Structural and functional analysis of the mitotic rotamase Pinl suggests substrate recognition is phosphorylation dependent. Cell 1997, 89(6): 875-886
-
(1997)
Cell
, vol.89
, Issue.6
, pp. 875-886
-
-
Ranganathan, R.1
Lu, K.P.2
Hunter, T.3
Noel, J.P.4
-
6
-
-
34548660854
-
Prolyl cis-trans isomerization as a molecular timer
-
DOI 10.1038/nchembio.2007.35, PII NCHEMBIO200735
-
Lu, K.P., Finn, G., Lee, T.H. and Nicholson, L.K. Prolyl cis-trans isomerization as a molecular timer. Nat Chem Biol 2007, 3(10): 619-629 (Pubitemid 47417709)
-
(2007)
Nature Chemical Biology
, vol.3
, Issue.10
, pp. 619-629
-
-
Lu, K.P.1
Finn, G.2
Lee, T.H.3
Nicholson, L.K.4
-
9
-
-
33745800493
-
Theoretical and experimental investigation of the energetics of cis-trans proline isomerization in peptide models
-
DOI 10.1021/jp060642u
-
Schroeder, O.E., Carper, E., Wind, J.J., Poutsma, J.L., Etzkorn, F.A. and Poutsma, J.C. Theoretical and experimental investigation of the energetics of cis-trans proline isomerization in peptide models. J Phys Chem A 2006, 110(20): 6522-6530 (Pubitemid 44020306)
-
(2006)
Journal of Physical Chemistry a
, vol.110
, Issue.20
, pp. 6522-6530
-
-
Schroeder, O.E.1
Carper, E.2
Wind, J.J.3
Poutsma, J.L.4
Etzkorn, F.A.5
Poutsma, J.C.6
-
10
-
-
0035947078
-
Pin1 acts catalytically to promote a conformational change in Cdc25
-
Stukenberg, P.T. and Kirschner, M.W. Pin1 acts catalytically to promote a conformational change in Cdc25. Mol Cell 2001, 7(5): 1071-83.
-
(2001)
Mol Cell
, vol.7
, Issue.5
, pp. 1071-1083
-
-
Stukenberg, P.T.1
Kirschner, M.W.2
-
11
-
-
0037073713
-
Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage
-
DOI 10.1074/jbc.C200538200
-
Wulf, G.M., Liou, Y.C., Ryo, A., Lee, S.W. and Lu, K.P. Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage. J Biol Chem 2002, 277(50): 47976-47979 (Pubitemid 35470742)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.50
, pp. 47976-47979
-
-
Wulf, G.M.1
Liou, Y.-C.2
Ryo, A.3
Lee, S.W.4
Lu, K.P.5
-
12
-
-
27744536481
-
Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells
-
DOI 10.1074/jbc.M504548200
-
Eckerdt, F., Yuan, J., Saxena, K. et al. Polo-like kinase 1-mediated phosphorylation stabilizes Pinl by inhibiting its ubiquitination in human cells. J Biol Chem 2005, 280(44): 36575-36583 (Pubitemid 41587733)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.44
, pp. 36575-36583
-
-
Eckerdt, F.1
Yuan, J.2
Saxena, K.3
Martin, B.4
Kappel, S.5
Lindenau, C.6
Kramer, A.7
Neumann, S.8
Daum, S.9
Fischer, G.10
Dikic, I.11
Kaufmann, M.12
Strebhardt, K.13
-
13
-
-
0033638180
-
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
-
Zhou, X.Z., Kops, O., Werner, A. et al. Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins. Mol Cell 2000, 6(4): 873-883
-
(2000)
Mol Cell
, vol.6
, Issue.4
, pp. 873-883
-
-
Zhou, X.Z.1
Kops, O.2
Werner, A.3
-
14
-
-
0032741457
-
Phosphorylation-dependent prolyl isomerization: A novel signaling regulatory mechanism
-
Zhou, X.Z., Lu, P.J., Wulf, G. and Lu, K.P. Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism. Cell Mol Life Sci 1999, 56(9-10): 788-806.
-
(1999)
Cell Mol Life Sci
, vol.56
, Issue.9-10
, pp. 788-806
-
-
Zhou, X.Z.1
Lu, P.J.2
Wulf, G.3
Lu, K.P.4
-
15
-
-
0032031634
-
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins
-
Shen, M., Stukenberg, P.T., Kirschner, M.W. and Lu, K.P. The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Genes Dev 1998, 12(5): 706-720 (Pubitemid 28134302)
-
(1998)
Genes and Development
, vol.12
, Issue.5
, pp. 706-720
-
-
Shen, M.1
Stukenberg, P.T.2
Kirschner, M.W.3
Lu, K.P.4
-
16
-
-
37549060330
-
New insights into mitotic chromosome condensation: A role for the prolyl isomerase Pin1
-
Xu, Y.X. and Manley, J.L. New insights into mitotic chromosome condensation: a role for the prolyl isomerase Pin1. Cell Cycle 2007, 6(23): 2896-2901
-
(2007)
Cell Cycle
, vol.6
, Issue.23
, pp. 2896-2901
-
-
Xu, Y.X.1
Manley, J.L.2
-
17
-
-
34247196176
-
The prolyl isomerase Pin1 functions in mitotic chromosome condensation
-
Xu, Y.X. and Manley, J.L. The prolyl isomerase Pin1 functions in mitotic chromosome condensation. Mol Cell 2007, 26(2): 287-300.
-
(2007)
Mol Cell
, vol.26
, Issue.2
, pp. 287-300
-
-
Xu, Y.X.1
Manley, J.L.2
-
18
-
-
33846002376
-
betatrcp
-
DOI 10.1038/sj.embor.7400853, PII 7400853
-
Bernis, C., Vigneron, S., Burgess, A. et al. Pin1 stabilizes Emi1 during G2 phase by preventing its association with SCF(betatrcp). EMBO Rep 2007, 8(1): 91-98 (Pubitemid 46043806)
-
(2007)
EMBO Reports
, vol.8
, Issue.1
, pp. 91-98
-
-
Bernis, C.1
Vigneron, S.2
Burgess, A.3
Labbe, J.-C.4
Fesquet, D.5
Castro, A.6
Lorca, T.7
-
19
-
-
0033854422
-
Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis
-
Rippmann, J.F., Hobbie, S., Daiber, C. et al. Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis. Cell Growth Differ 2000, 11(7): 409-416 (Pubitemid 30619568)
-
(2000)
Cell Growth and Differentiation
, vol.11
, Issue.7
, pp. 409-416
-
-
Rippmann, J.F.1
Hobbie, S.2
Daiber, C.3
Guilliard, B.4
Bauer, M.5
Birk, J.6
Nar, H.7
Garin-Chesa, P.8
Rettig, W.J.9
Schnapp, A.10
-
20
-
-
0034050649
-
Requirement of the prolyl isomerase Pin1 for the replication checkpoint
-
DOI 10.1126/science.287.5458.1644
-
Winkler, K.E., Swenson, K.I., Kornbluth, S. and Means, A.R. Requirement of the prolyl isomerase Pin1 for the replication checkpoint. Science 2000, 287(5458): 1644-1647 (Pubitemid 30127764)
-
(2000)
Science
, vol.287
, Issue.5458
, pp. 1644-1647
-
-
Winkler, K.E.1
Swenson, K.I.2
Kornbluth, S.3
Means, A.R.4
-
21
-
-
0037022355
-
Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes
-
DOI 10.1073/pnas.032404099
-
Liou, Y.C., Ryo, A., Huang, H.K. et al. Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes. Proc Natl Acad Sci U S A 2002, 99(3): 1335-1340 (Pubitemid 34136494)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.3
, pp. 1335-1340
-
-
Liou, Y.-C.1
Ryo, A.2
Huang, H.-K.3
Lu, P.-J.4
Bronson, R.5
Fujimori, F.6
Uchida, T.7
Hunter, T.8
Lu, K.P.9
-
22
-
-
0037351048
-
Prolyl isomerase Pin1: A catalyst for oncogenesis and a potential therapeutic target in cancer
-
DOI 10.1242/jcs.00276
-
Ryo, A., Liou, Y.C., Lu, K.P. and Wulf, G. Prolyl Isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. J Cell Sci 2003, 116(Pt 5): 773-783 (Pubitemid 36367627)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.5
, pp. 773-783
-
-
Ryo, A.1
Liou, Y.-C.2
Lu, K.P.3
Wulf, G.4
-
23
-
-
0035796405
-
Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1
-
DOI 10.1093/emboj/20.13.3459
-
Wulf, G.M., Ryo, A., Wulf, G.C. et al. Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. Embo J 2001, 20(13): 3459-3472 (Pubitemid 32634353)
-
(2001)
EMBO Journal
, vol.20
, Issue.13
, pp. 3459-3472
-
-
Wulf, G.M.1
Ryo, A.2
Wulf, G.G.3
Lee, S.W.4
Niu, T.5
Petkova, V.6
Lu, K.P.7
-
24
-
-
27444440554
-
Regulation of the transcriptional activity of c-Fos by ERK: A novel role for the prolyl isomerase Pin1
-
DOI 10.1074/jbc.C500353200
-
Monje, P., Hernandez-Losa, J., Lyons, R.J., Castellone, M.D. and Gutkind, J.S. Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase Pin1. J Biol Chem 2005, 280(42): 35081-35084 (Pubitemid 41532693)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.42
, pp. 35081-35084
-
-
Monje, P.1
Hernandez-Losa, J.2
Lyons, R.J.3
Castellone, M.D.4
Gutkind, J.S.5
-
25
-
-
18644384283
-
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults
-
DOI 10.1038/nature01120
-
Zacchi, P., Gostissa, M., Uchida, T. et al. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature 2002, 419(6909): 853-857 (Pubitemid 35238573)
-
(2002)
Nature
, vol.419
, Issue.6909
, pp. 853-857
-
-
Zacchi, P.1
Gostissa, M.2
Uchida, T.3
Salvagno, C.4
Avolio, F.5
Volinia, S.6
Ronai, Z.7
Blandino, G.8
Schneider, C.9
Del Sal, G.10
-
26
-
-
18644384688
-
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response
-
DOI 10.1038/nature01116
-
Zheng, H., You, H., Zhou, X.Z. et al. The prolyl Isomerase Pin1 is a regulator of p53 in genotoxic response. Nature 2002, 419(6909): 849-53. (Pubitemid 35238572)
-
(2002)
Nature
, vol.419
, Issue.6909
, pp. 849-853
-
-
Zheng, H.1
You, H.2
Zhou, X.Z.3
Murray, S.A.4
Uchida, T.5
Wulf, G.6
Gu, L.7
Tang, X.8
Lu, K.P.9
Xiao, Z.-X.J.10
-
27
-
-
2942547565
-
Pin1 links the activities of c-Abl and p300 in regulating p73 function
-
DOI 10.1016/j.molcel.2004.05.007, PII S1097276504002904
-
Mantovani, F., Piazza, S., Gostissa, M. et al. Pin1 Write the activities of c-Abl and p300 in regulating p73 function. Mol Cell 2004, 14(5): 625-636 (Pubitemid 38739084)
-
(2004)
Molecular Cell
, vol.14
, Issue.5
, pp. 625-636
-
-
Mantovani, F.1
Piazza, S.2
Gostissa, M.3
Strano, S.4
Zacchi, P.5
Mantovani, R.6
Blandino, G.7
Del Sal, G.8
-
28
-
-
27144480681
-
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1)
-
Yi, P., Wu, R.C., Sandquist, J. et al. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol 2005, 25(21): 9687-9699
-
(2005)
Mol Cell Biol
, vol.25
, Issue.21
, pp. 9687-9699
-
-
Yi, P.1
Wu, R.C.2
Sandquist, J.3
-
29
-
-
4644283087
-
Pinning down transcription: Regulation of RNA polymerase II activity during the cell cycle
-
Xu, Y.X. and Manley, J.L. Pinning down transcription: regulation of RNA polymerase II activity during the cell cycle. Cell Cycle 2004, 3(4): 432-435
-
(2004)
Cell Cycle
, vol.3
, Issue.4
, pp. 432-435
-
-
Xu, Y.X.1
Manley, J.L.2
-
30
-
-
34547132819
-
The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage
-
DOI 10.1074/jbc.M610282200
-
De Nicola, F., Bruno, T., Iezzi, S. et al. The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage. J Biol Chem 2007, 282(27): 19685-19691 (Pubitemid 47100057)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.27
, pp. 19685-19691
-
-
De Nicola, F.1
Bruno, T.2
Iezzi, S.3
Di Padova, M.4
Floridi, A.5
Passananti, C.6
Del Sal, G.7
Fanciulli, M.8
-
31
-
-
20744432450
-
Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage
-
DOI 10.1128/MCB.25.13.5380-5388.2005
-
Berger, M., Stahl, N., Del Sal, G. and Haupt, Y. Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage. Mol Cell Biol 2005, 25(13): 5380-5388 (Pubitemid 40853575)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.13
, pp. 5380-5388
-
-
Berger, M.1
Stahl, N.2
Del Sal, G.3
Haupt, Y.4
-
32
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
DOI 10.1016/S0014-5793(97)01480-4, PII S0014579397014804
-
Honda, R., Tanaka, H. and Yasuda, H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 1997, 420(1): 25-27 (Pubitemid 28037193)
-
(1997)
FEBS Letters
, vol.420
, Issue.1
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
33
-
-
1942533406
-
Prevalent Overexpression of Prolyl Isomerase Pin1 in Human Cancers
-
Bao, L., Kimzey, A., Sauter, G., Sowadski, J.M., Lu, K.P. and Wang, D.G. Prevalent overexpression of prolyl Isomerase Pin1 in human cancers. Am J Pathol 2004, 164(5): 1727-1737 (Pubitemid 38529775)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.5
, pp. 1727-1737
-
-
Bao, L.1
Kimzey, A.2
Sauter, G.3
Sowadski, J.M.4
Lu, K.P.5
Wang, D.-G.6
-
34
-
-
0042476570
-
Pin1 regulates the timing of mammalian primordial germ cell proliferation
-
DOI 10.1242/dev.00584
-
Atchison, F.W., Capel, B. and Means, A.R. Pin1 regulates the timing of mammalian primordial germ cell proliferation. Development 2003, 130(15): 3579-3586 (Pubitemid 37010020)
-
(2003)
Development
, vol.130
, Issue.15
, pp. 3579-3586
-
-
Atchison, F.W.1
Capel, B.2
Means, A.R.3
-
35
-
-
40849126563
-
Induction of vascular endothelial growth factor by peptidyl-prolyl isomerase Pin1 in breast cancer cells
-
Kim, M.R., Choi, H.S., Heo, T.H., Hwang, S.W. and Kang, K.W. Induction of vascular endothelial growth factor by peptidyl-prolyl isomerase Pin1 in breast cancer cells. Biochem Biophys Res Commun 2008, 369(2): 547-553
-
(2008)
Biochem Biophys Res Commun
, vol.369
, Issue.2
, pp. 547-553
-
-
Kim, M.R.1
Choi, H.S.2
Heo, T.H.3
Hwang, S.W.4
Kang, K.W.5
-
36
-
-
38549132438
-
Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 ce11s
-
DOI 10.1128/MCB.01848-07
-
Reineke, E.L., Lam, M., Liu, Q. et al. Degradation of the tumor suppressor PML by Pinl contributes to the cancer phenotype of breast cancer MDA-MB-231 cells. Mol Cell Biol 2008, 28(3): 997-1006. (Pubitemid 351160056)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.3
, pp. 997-1006
-
-
Reineke, E.L.1
Lam, M.2
Liu, Q.3
Liu, Y.4
Stanya, K.J.5
Chang, K.-S.6
Means, A.R.7
Kao, H.-Y.8
-
37
-
-
4444309643
-
Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis
-
Wulf, G., Garg, P., Liou, Y.C., Iglehart, D. and Lu, K.P. Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis. Embo J 2004, 23(16): 3397-3407
-
(2004)
Embo J
, vol.23
, Issue.16
, pp. 3397-3407
-
-
Wulf, G.1
Garg, P.2
Liou, Y.C.3
Iglehart, D.4
Lu, K.P.5
-
38
-
-
2942588392
-
PIN1 overexpression and beta-catenin gene mutations are distinct oncogenic events in human hepatocellular carcinoma
-
DOI 10.1038/sj.onc.1207493
-
Pang, R., Yuen, J., Yuen, M.F. et al. PIN1 overexpression and beta-catenin gene mutations are distinct oncogenic events in human hepatocellular carcinoma. Oncogene 2004, 23(23): 4182-4186 (Pubitemid 38747951)
-
(2004)
Oncogene
, vol.23
, Issue.23
, pp. 4182-4186
-
-
Pang, R.1
Yuen, J.2
Yuen, M.F.3
Lai, C.L.4
Lee, T.K.W.5
Man, K.6
Poon, R.T.P.7
Fan, S.T.8
Wong, C.M.9
Ng, I.O.L.10
Kwong, Y.L.11
Tse, E.12
-
39
-
-
33947303068
-
Pin1 Interacts with a Specific Serine-Proline Motif of Hepatitis B Virus X-Protein to Enhance Hepatocarcinogenesis
-
DOI 10.1053/j.gastro.2006.12.030, PII S0016508506026801
-
Pang, R., Lee, T.K., Poon, R.T. et al. Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. Gastroenterology 2007, 132(3): 1088-1103 (Pubitemid 46440863)
-
(2007)
Gastroenterology
, vol.132
, Issue.3
, pp. 1088-1103
-
-
Pang, R.1
Lee, T.K.W.2
Poon, R.T.P.3
Fan, S.T.4
Wong, K.B.5
Kwong, Y.6
Tse, E.7
-
40
-
-
33847626362
-
Overexpression of Pin1 in non-small cell lung cancer (NSCLC) and its correlation with lymph node metastases
-
DOI 10.1016/j.lungcan.2006.11.024, PII S0169500206006258
-
He, J., Zhou, F., Shao, K. et al. Overexpression of Pinl in non-small cell lung cancer (NSCLC) and its correlation with lymph node metas- tases. Lung Cancer 2007, 56(1): 51-58 (Pubitemid 46356645)
-
(2007)
Lung Cancer
, vol.56
, Issue.1
, pp. 51-58
-
-
He, J.1
Zhou, F.2
Shao, K.3
Hang, J.4
Wang, H.5
Rayburn, E.6
Xiao, Z.-X.7
Lee, S.W.8
Xue, Q.9
Feng, X.-L.10
Shi, S.-S.11
Zhang, C.-Y.12
Zhang, S.13
-
41
-
-
34247464252
-
Prolyl isomerase Pin1 expression predicts prognosis in patients with esophageal squamous cell carcinoma and correlates with cyclinD1 expression
-
Fukuchi, M., Fukai, Y., Kimura, H. et al. Prolyl isomerase Pin1 expression predicts prognosis in patients with esophageal squamous cell carcinoma and correlates with cyclinD1 expression. Int J Oncol 2006, 29(2): 329-334
-
(2006)
Int J Oncol
, vol.29
, Issue.2
, pp. 329-334
-
-
Fukuchi, M.1
Fukai, Y.2
Kimura, H.3
-
42
-
-
33749173169
-
Pin1 contributes to cervical tumorigenesis by regulating cyclin D1 expression
-
Li, H., Wang, S., Zhu, T. et al. Pin1 contributes to cervical tumorigenesis by regulating cyclin D1 expression. Oncol Rep 2006, 16(3): 491-496
-
(2006)
Oncol Rep
, vol.16
, Issue.3
, pp. 491-496
-
-
Li, H.1
Wang, S.2
Zhu, T.3
-
43
-
-
33747127543
-
High Pin1 expression is associated with tumor progression in colorectal cancer
-
DOI 10.1002/jso.20510
-
Kuramochi, J., Arai, T., Ikeda, S., Kumagai, J., Uetake, H. and Sugihara, K. High Pin1 expression is associated with tumor progression in colorectal cancer. J Surg Oncol 2006, 94(2): 155-160 (Pubitemid 44267198)
-
(2006)
Journal of Surgical Oncology
, vol.94
, Issue.2
, pp. 155-160
-
-
Kuramochi, J.1
Arai, T.2
Ikeda, S.3
Kumagai, J.4
Uetake, H.5
Sugihara, K.6
-
44
-
-
31344433667
-
Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase pin1-mediated abrogation of the androgen receptor-beta-catenin interaction
-
DOI 10.1128/MCB.26.3.929-939.2006
-
Chen, S.Y., Wulf, G., Zhou, X.Z., Rubin, M.A., Lu, K.P. and Balk, S.P. Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction. Mol Cell Biol 2006, 26(3): 929-39. (Pubitemid 43146487)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.3
, pp. 929-939
-
-
Chen, S.-Y.1
Wulf, G.2
Zhou, X.Z.3
Rubin, M.A.4
Lu, K.P.5
Balk, S.P.6
-
45
-
-
11144356374
-
Cyclin D1 overexpression in thyroid tumours from a radio-contaminated area and its correlation with Pin1 and aberrant beta-catenin expression
-
DOI 10.1002/path.1534
-
Nakashima, M., Meirmanov, S., Naruke, Y. et al. Cyclin D1 overexpression in thyroid tumours from a radio-contaminated area and its correlation with Pin1 and aberrant beta-catenin expression. J Pathol 2004, 202(4): 446-455 (Pubitemid 38456163)
-
(2004)
Journal of Pathology
, vol.202
, Issue.4
, pp. 446-455
-
-
Nakashima, M.1
Meirmanov, S.2
Naruke, Y.3
Kondo, H.4
Saenko, V.5
Rogounovitch, T.6
Shimizu-Yoshida, Y.7
Takamura, N.8
Namba, H.9
Ito, M.10
Abrosimov, A.11
Lushnikov, E.12
Roumiantsev, P.13
Tsyb, A.14
Yamashita, S.15
Sekine, I.16
-
46
-
-
0038825052
-
Pin1 is overexpressed in oral squamous cell carcinoma and its levels correlate with cyclin D1 overexpression
-
Miyashita, H., Mori, S., Motegi, K., Fukumoto, M. and Uchida, T. Pin1 is overexpressed in oral squamous cell carcinoma and its levels correlate with cyclin D1 overexpression. Oncol Rep 2003, 10(2): 455-461
-
(2003)
Oncol Rep
, vol.10
, Issue.2
, pp. 455-461
-
-
Miyashita, H.1
Mori, S.2
Motegi, K.3
Fukumoto, M.4
Uchida, T.5
-
47
-
-
1542577405
-
Expression status of Pin1 and cyclins in oral squamous cell carcinoma: Pin1 correlates with Cyclin D1 mRNA expression and clinical significance of cyclins
-
Miyashita, H., Uchida, T., Mori, S., Echigo, S. and Motegi, K. Expression status of Pin1 and cyclins in oral squamous cell carcinoma: Pin1 correlates with Cyclin D1 mRNA expression and clinical significance of cyclins. Oncol Rep 2003, 10(4): 1045-1048
-
(2003)
Oncol Rep
, vol.10
, Issue.4
, pp. 1045-1048
-
-
Miyashita, H.1
Uchida, T.2
Mori, S.3
Echigo, S.4
Motegi, K.5
-
48
-
-
0023150161
-
Role of transcriptional and posttranscriptional regulation in expression of histone genes in Saccharomyces cerevisiae
-
Lycan, D.E., Osley, M.A. and Hereford, L.M. Role of transcriptional and posttranscriptional regulation in expression of histone genes in Saccharomyces cerevisiae. Mol Cell Biol 1987, 7(2): 614-621
-
(1987)
Mol Cell Biol
, vol.7
, Issue.2
, pp. 614-621
-
-
Lycan, D.E.1
Osley, M.A.2
Hereford, L.M.3
-
49
-
-
0043069764
-
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
-
DOI 10.1038/nature01832
-
Liou, Y.C., Sun, A., Ryo, A. et al. Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. Nature 2003, 424(6948): 556-561 (Pubitemid 36975777)
-
(2003)
Nature
, vol.424
, Issue.6948
, pp. 556-561
-
-
Liou, Y.-C.1
Sun, A.2
Ryo, A.3
Zhou, X.Z.4
Yu, Z.-X.5
Huang, H.-K.6
Uchida, T.7
Bronson, R.8
Bing, G.9
Li, X.10
Hunter, T.11
Lu, K.P.12
-
50
-
-
33645300736
-
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production
-
Pastorino, L., Sun, A., Lu, P.J. et al. The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. Nature 2006, 440(7083): 528-534
-
(2006)
Nature
, vol.440
, Issue.7083
, pp. 528-534
-
-
Pastorino, L.1
Sun, A.2
Lu, P.J.3
-
51
-
-
24644444767
-
Pin1 promotes production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein
-
DOI 10.1016/j.bbrc.2005.08.130, PII S0006291X05018401
-
Akiyama, H., Shin, R.W., Uchida, C., Kitamoto, T. and Uchida, T. Pin1 promotes production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein. Biochem Biophys Res Commun 2005, 336(2): 521-529 (Pubitemid 41267260)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.336
, Issue.2
, pp. 521-529
-
-
Akiyama, H.1
Shin, R.-W.2
Uchida, C.3
Kitamoto, T.4
Uchida, T.5
-
52
-
-
39049193441
-
Pin1 flips Alzheimer's switch
-
Etzkorn, F.A. Pin1 flips Alzheimer's switch. ACS Chem Biol 2006, 1(4): 214-216
-
(2006)
ACS Chem Biol
, vol.1
, Issue.4
, pp. 214-216
-
-
Etzkorn, F.A.1
-
53
-
-
0036786838
-
Substrate-based design of reversible Pin1 inhibitors
-
Zhang, Y., Fussel, S., Reimer, U., Schutkowski, M. and Fischer, G. Substrate-based design of reversible Pin1 inhibitors. Biochemistry 2002, 41(39): 11868-11877
-
(2002)
Biochemistry
, vol.41
, Issue.39
, pp. 11868-11877
-
-
Zhang, Y.1
Fussel, S.2
Reimer, U.3
Schutkowski, M.4
Fischer, G.5
-
54
-
-
33645680245
-
Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries
-
Wildemann, D., Erdmann, F., Alvarez, B.H. et al. Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries. J Med Chem 2006, 49(7): 2147-2150
-
(2006)
J Med Chem
, vol.49
, Issue.7
, pp. 2147-2150
-
-
Wildemann, D.1
Erdmann, F.2
Alvarez, B.H.3
-
55
-
-
9644302270
-
Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere
-
Wang, X.J., Xu, B., Mullins, A.B., Neiler, F.K. and Etzkorn, F.A. Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere. J Am Chem Soc 2004, 126(47): 15533-15542 (Pubitemid 39577489)
-
(2004)
Journal of the American Chemical Society
, vol.126
, Issue.47
, pp. 15533-15542
-
-
Wang, X.J.1
Xu, B.2
Mullins, A.B.3
Neiler, F.K.4
Etzkorn, F.A.5
-
56
-
-
35648979497
-
A phosphorylated prodrug for the inhibition of Pin1
-
Zhao, S. and Etzkorn, F.A. A phosphorylated prodrug for the inhibition of Pin1. Bioorg Med Chem Lett 2007, 17(23): 6615-6618
-
(2007)
Bioorg Med Chem Lett
, vol.17
, Issue.23
, pp. 6615-6618
-
-
Zhao, S.1
Etzkorn, F.A.2
-
58
-
-
33751234234
-
Aryl indanyl ketones: Efficient inhibitors of the human peptidyl prolyl cis/trans isomerase Pin1
-
Daum, S., Erdmann, F., Fischer, G. et al. Aryl indanyl ketones: efficient inhibitors of the human peptidyl prolyl cis/trans isomerase Pin1. Angew Chem Int Ed Engl 2006, 45(44): 7454-7458
-
(2006)
Angew Chem Int Ed Engl
, vol.45
, Issue.44
, pp. 7454-7458
-
-
Daum, S.1
Erdmann, F.2
Fischer, G.3
-
59
-
-
43049124394
-
Novel spiroannulated 3-benzofuranones. Synthesis and inhibition of the human peptidyl prolyl cis/trans isomerase Pin1
-
Braun, M., Hessamian-Alinejad, A., Lacroix, B.F.d., Alvarez, B.H. and Fischer, G. Novel spiroannulated 3-benzofuranones. Synthesis and inhibition of the human peptidyl prolyl cis/trans isomerase Pin1 Molecules 2008, 13: 995-1003.
-
(2008)
Molecules
, vol.13
, pp. 995-1003
-
-
Braun, M.1
Hessamian-Alinejad, A.2
Lacroix, B.F.D.3
Alvarez, B.H.4
Fischer, G.5
-
60
-
-
34250677715
-
A novel synthesis of highly substituted perhydropyrrolizines, perhydroindolizines, and pyrrolidines: Inhibition of the peptidyl-prolyl cis/trans isomerase (PPIase) Pin1
-
DOI 10.1002/hlca.200790028
-
Siegrist, R., Zürcher, M., Baumgartner, C. et al. A novel synthesis of highly substituted perhydropyrrolizines, perhydroindolizines, and pyrrolidines: Inhibition of the peptidyl-prolyl cis/trans isomerase (PPIase) Pin1. Helv Chim Acta 2007, 90: 217-259 (Pubitemid 46931558)
-
(2007)
Helvetica Chimica Acta
, vol.90
, Issue.2
, pp. 217-259
-
-
Siegrist, R.1
Zurcher, M.2
Baumgartner, C.3
Seiler, P.4
Diederich, F.5
Daum, S.6
Fischer, G.7
Klein, C.8
Dangl, M.9
Schwaiger, M.10
-
61
-
-
22744432396
-
Control of protein-protein interactions: Structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides
-
DOI 10.1021/jm0500119
-
Smet, C., Duckert, J.F., Wieruszeski, J.M. et al. Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides. J Med Chem 2005, 48(15): 4815-5523 (Pubitemid 41033124)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.15
, pp. 4815-4823
-
-
Smet, C.1
Duckert, J.-F.2
Wieruszeski, J.-M.3
Landrieu, I.4
Buee, L.5
Lippens, G.6
Deprez, B.7
-
62
-
-
37849032065
-
Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins
-
Li, M., Stukenberg, P.T. and Brautigan, D.L. Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins. Biochemistry 2008, 47(1): 292-300.
-
(2008)
Biochemistry
, vol.47
, Issue.1
, pp. 292-300
-
-
Li, M.1
Stukenberg, P.T.2
Brautigan, D.L.3
-
63
-
-
0028865511
-
Regulation of chromosome segregation by Glc8p, a structural homolog of mammalian inhibitor 2 that functions as both an activator and an inhibitor of yeast protein phosphatase 1
-
Tung, H.Y., Wang, W. and Chan, C.S. Regulation of chromosome segregation by Glc8p, a structural homolog of mammalian inhibitor 2 that functions as both an activator and an inhibitor of yeast protein phosphatase 1. Mol Cell Biol 1995, 15(11): 6064-6074
-
(1995)
Mol Cell Biol
, vol.15
, Issue.11
, pp. 6064-6074
-
-
Tung, H.Y.1
Wang, W.2
Chan, C.S.3
-
64
-
-
0032574832
-
Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone
-
DOI 10.1021/bi973162p
-
Hennig, L., Christner, C., Kipping, M. et al. Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomeroses by juglone. Biochemistry 1998, 37(17): 5953-5960 (Pubitemid 28196748)
-
(1998)
Biochemistry
, vol.37
, Issue.17
, pp. 5953-5960
-
-
Hennig, L.1
Christner, C.2
Kipping, M.3
Schelbert, B.4
Rucknagel, K.P.5
Grabley, S.6
Kullertz, G.7
Fischer, G.8
-
65
-
-
0035253619
-
Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription
-
Chao, S.H., Greenleaf, A.L. and Price, D.H. Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription. Nucleic Acids Res 2001, 29(3): 767-773
-
(2001)
Nucleic Acids Res
, vol.29
, Issue.3
, pp. 767-773
-
-
Chao, S.H.1
Greenleaf, A.L.2
Price, D.H.3
-
66
-
-
0025216877
-
Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis
-
Liu, J., Albers, M.W., Chen, C.M., Schreiber, S.L. and Walsh, C.T. Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis. Proc Natl Acad Sci U S A 1990, 87(6): 2304-2308 (Pubitemid 20105305)
-
(1990)
Proceedings of the National Academy of Sciences of the United States of America
, vol.87
, Issue.6
, pp. 2304-2308
-
-
Liu, J.1
Albers, M.W.2
Chen, C.3
Schreiber, S.L.4
Walsh, C.T.5
-
67
-
-
0037256548
-
Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation
-
DOI 10.1016/S1074-5521(02)00310-1
-
Uchida, T., Takamiya, M., Takahashi, M. et al. Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation. Chem Biol 2003, 10(1): 15-24. (Pubitemid 36154470)
-
(2003)
Chemistry and Biology
, vol.10
, Issue.1
, pp. 15-24
-
-
Uchida, T.1
Takamiya, M.2
Takahashi, M.3
Miyashita, H.4
Ikeda, H.5
Terada, T.6
Matsuo, Y.7
Shirouzu, M.8
Yokoyama, S.9
Fujimori, F.10
Hunter, T.11
-
68
-
-
34548490722
-
Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons
-
DOI 10.1091/mbc.E07-03-0237
-
Kesavapany, S., Patel, V., Zheng, Y.L. et al. Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons. Mol Biol Cell 2007, 18(9): 3645-3655 (Pubitemid 47378701)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.9
, pp. 3645-3655
-
-
Kesavapany, S.1
Patel, V.2
Zheng, Y.-L.3
Pareek, T.K.4
Bjelogrlic, M.5
Albers, W.6
Amin, N.7
Jaffe, H.8
Gutkind, J.S.9
Strong, M.J.10
Grant, P.11
Pant, H.C.12
-
69
-
-
13244271985
-
Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell line
-
DOI 10.1039/b414037k
-
Bayer, E., Thutewohl, M., Christner, C. et al. Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell line. Chem Commun (Camb) 2005, (4): 516-518 (Pubitemid 40187678)
-
(2005)
Chemical Communications
, Issue.4
, pp. 516-518
-
-
Bayer, E.1
Thutewohl, M.2
Christner, C.3
Tradler, T.4
Osterkamp, F.5
Waldmann, H.6
Bayer, P.7
-
70
-
-
0038334904
-
Identification of mono- And bisubstrate inhibitors of protein farnesyltransferase and inducers of apoptosis from a pepticinnamin e library
-
DOI 10.1016/S0968-0896(03)00160-3
-
Thutewohl, M., Kissau, L., Popkirova, B. et al. Identification of mono- and bisubstrate inhibitors of protein farnesyltransferase and inducers of apoptosis from a pepticinnamin E library. Bioorg Med Chem 2003, 11(12): 2617-26. (Pubitemid 36566622)
-
(2003)
Bioorganic and Medicinal Chemistry
, vol.11
, Issue.12
, pp. 2617-2626
-
-
Thutewohl, M.1
Kissau, L.2
Popkirova, B.3
Karaguni, I.-M.4
Nowak, T.5
Bate, M.6
Kuhlmann, J.7
Muller, O.8
Waldmann, H.9
-
71
-
-
0141457429
-
Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics
-
DOI 10.1016/S1535-6108(03)00218-6
-
Lu, K.P. Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics. Cancer Cell 2003, 4(3): 175-180 (Pubitemid 37163831)
-
(2003)
Cancer Cell
, vol.4
, Issue.3
, pp. 175-180
-
-
Lu, K.P.1
-
72
-
-
43449088839
-
Phosphorylation-specific prolyl isomerase Pin1 as a new diagnostic and therapeutic target for cancer
-
DOI 10.2174/156800908784293622
-
Finn, G. and Lu, K.P. Phosphorylation-specific prolyl isomerase Pin1 as a new diagnostic and therapeutic target for cancer. Curr Cancer Drug Targets 2008, 8(3): 223-229 (Pubitemid 351666858)
-
(2008)
Current Cancer Drug Targets
, vol.8
, Issue.3
, pp. 223-229
-
-
Finn, G.1
Kun, P.L.2
|